Abood, A. A., Hellfritzsch, M. B., Møller-Madsen, B., Brüel, A., Westersø, T. S., Vedel-Smith, N. K., Rahbek, O. & Rölfing, J. D. (2022). Controlled rotation of long bones by guided growth: A proof of concept study of a novel plate in cadavers. Journal of Orthopaedic Research, 40(5), 1075-1082. https://doi.org/10.1002/jor.25148

Bjerre, H. L., Christensen, J. B., Buus, N. H., Simonsen, U. & Su, J. (2022). Correction: The role of aliskiren in the management of hypertension and major cardiovascular outcomes: a systematic review and meta-analysis (Journal of Human Hypertension, (2019), 33, 11, (795-806), 10.1038/s41371-018-0149-8). Journal of Human Hypertension, 36(10), 942. https://doi.org/10.1038/s41371-022-00739-0

Ferreira, N., Richner, M., van der Laan, A., Jul Christiansen, I. B., Vægter, C. B., Nyengaard, J. R., Halliday, G. M., Weis, J., Giasson, B. I., Mackenzie, I. R., Jensen, P. H. & Jan, A. (2022). Correction to: Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. Brain Communications, 4(2), fcac067. https://doi.org/10.1093/braincomms/fcac067

Abd El-Maksoud, A. A., Cheng, W., Petersen, S. V., Pandiselvam, R. & Guo, Z. (2022). Covalent phenolic acid-grafted β-lactoglobulin conjugates: Synthesis, characterization, and evaluation of their multifunctional properties. LWT - Food Science and Technology, 172, Article 114215. https://doi.org/10.1016/j.lwt.2022.114215

Thomsen, E. A., Skipper, K. A., Andersen, S., Haslund, D., Skov, T. W. & Mikkelsen, J. G. (2022). CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch. Molecular Therapy - Nucleic Acids, 29, 563-576. https://doi.org/10.1016/j.omtn.2022.08.005

Corsi, G. I., Qu, K., Alkan, F., Pan, X., Luo, Y. & Gorodkin, J. (2022). CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context. Nature Communications, 13(1), Article 3006. https://doi.org/10.1038/s41467-022-30515-0

Ravendran, S., Hernández, S. S., König, S. & Bak, R. O. (2022). CRISPR/Cas-Based Gene Editing Strategies for DOCK8 Immunodeficiency Syndrome. Frontiers in Genome Editing, 4, Article 793010. https://doi.org/10.3389/fgeed.2022.793010

Kanai, R., Cornelius, F., Vilsen, B. & Toyoshima, C. (2022). Cryoelectron microscopy of Na⁺,K⁺-ATPase in the two E2P states with and without cardiotonic steroids. Proceedings of the National Academy of Sciences, 119(15), Article e2123226119. https://doi.org/10.1073/pnas.2123226119

Kanai, R., Cornelius, F., Vilsen, B. & Toyoshima, C. (2022). Cryo-electron microscopy of Na⁺ ,K⁺ -ATPase reveals how the extracellular gate locks in the E2·2K⁺ state. FEBS Letters, 596(19), 2513-2524. https://doi.org/10.1002/1873-3468.14437

Neumann, C., Rosenbaek, L. L., Flygaard, R. K., Habeck, M., Karlsen, J. L., Wang, Y., Lindorff-Larsen, K., Gad, H. H., Hartmann, R., Lyons, J. A., Fenton, R. A. & Nissen, P. (2022). Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. The EMBO Journal, 41(23), Article e110169. https://doi.org/10.15252/embj.2021110169

Sedgwick, P. M., Hammer, A., Kesmodel, U. S. & Pedersen, L. H. (2022). Current controversies: Null hypothesis significance testing. Acta Obstetricia et Gynecologica Scandinavica, 101(6), 624-627. https://doi.org/10.1111/aogs.14366

Hansen, E., Grimm, D. & Wehland, M. (2022). Current Knowledge about the New Drug Firibastat in Arterial Hypertension. International Journal of Molecular Sciences , 23(3), Article 1459. https://doi.org/10.3390/ijms23031459

Bisinski, D., Castro, I. G., Mari, M. C., Walter, S., Frohlich, F., Schuldiner, M. & González Montoro, A. (2022). Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis. Journal of Cell Biology, 221(8), Article e202103048. https://doi.org/10.1083/jcb.202103048

Greisen, S. R., Mikkelsen, C., Hetland, M. L., Østergaard, M., Hørslev-Petersen, K., Junker, P., Stengaard-Petersen, K. & Deleuran, B. (2022). CXCL13 predicts long-term radiographic status in early rheumatoid arthritis. Rheumatology (Oxford, England), 61(6), 2590-2595. https://doi.org/10.1093/rheumatology/keab763

Khatri, S., Hansen, J., Pedersen, N. B., Brandt-Clausen, I. P., Gram-Nielsen, S., Mendes, A. C., Chronakis, I. S., Keiding, U. B., Catrina, A. I., Rethi, B., Clausen, M. H., Kragstrup, T. & Astakhova, K. (2022). Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis. Biomacromolecules, 23(5), 2126–2137. https://doi.org/10.1021/acs.biomac.2c00144

Ataei-Nazari, S., Amoushahi, M., Madsen, J. F., Jensen, J., Heuck, A., Mohammadi-Sangcheshmeh, A. & Lykke-Hartmann, K. (2022). Cyclin-dependent kinase 6 (CDK6) as a potent regulator of the ovarian primordial-to-primary follicle transition. Frontiers in Cell and Developmental Biology, 10, Article 1036917. https://doi.org/10.3389/fcell.2022.1036917

Madsen, J. F. (2022). Cyclin-dependent kinase 6 (CDK6) as a potent regulator of the ovarian primordial-to-primary follicle transition. Frontiers in Cell and Developmental Biology.

D'Acierno, M., Resaz, R., Iervolino, A., Nielsen, R., Sardella, D., Siccardi, S., Costanzo, V., D'Apolito, L., Suzumoto, Y., Segalerba, D., Astigiano, S., Perna, A. F., Capasso, G., Eva, A. & Trepiccione, F. (2022). Dapagliflozin Prevents Kidney Glycogen Accumulation and Improves Renal Proximal Tubule Cell Functions in a Mouse Model of Glycogen Storage Disease Type 1b. Journal of the American Society of Nephrology : JASN, 33(10), 1864-1875. https://doi.org/10.1681/ASN.2021070935

Jaegers, J., Haferkamp, S., Arnolds, O., Moog, D., Wrobeln, A., Nocke, F., Cantore, M., Pütz, S., Hartwig, A., Franzkoch, R., Psathaki, O. E., Jastrow, H., Schauerte, C., Stoll, R., Kirsch, M. & Ferenz, K. B. (2022). Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity. Langmuir, 38(34), 10351-10361. https://doi.org/10.1021/acs.langmuir.1c03388

Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, M., Børglum, A. D., Hougaard, D. M., Werge, T., Rasmussen, S. & Benros, M. E. (2022). Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression. Science Advances, 8(26), eabi7293. Article eabi7293. https://doi.org/10.1126/sciadv.abi7293

Wolff, J. H. & Mikkelsen, J. G. (2022). Delivering genes with human immunodeficiency virus-derived vehicles: still state-of-the-art after 25 years. Journal of Biomedical Science, 29, Article 79. https://doi.org/10.1186/s12929-022-00865-4

Narayanan, D., Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, M. & Bach, A. (2022). Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery. Journal of Medicinal Chemistry, 65(21), 14481–14526. https://doi.org/10.1021/acs.jmedchem.2c00830

Cehofski, L. J., Kruse, A., Mæng, M. O., Sejergaard, B. F., Schlosser, A., Sorensen, G. L., Grauslund, J., Honoré, B. & Vorum, H. (2022). Dexamethasone Intravitreal Implant Is Active at the Molecular Level Eight Weeks after Implantation in Experimental Central Retinal Vein Occlusion. Molecules (Basel, Switzerland), 27(17), Article 5687. https://doi.org/10.3390/molecules27175687

Al-Absi, A.-R., Thambiappa, S. K., Khan, A. R., Glerup, S., Sanchez, C., Landau, A. M. & Nyengaard, J. R. (2022). Df(h22q11)/+ mouse model exhibits reduced binding levels of GABA_A receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus. Molecular and Cellular Neuroscience, 122, Article 103769. https://doi.org/10.1016/j.mcn.2022.103769

Dyssekilde, J. R., Frederiksen, T. C., Christiansen, M. K., Hasle Sørensen, R., Pedersen, L. N., Loof Møller, P., Christensen, L. S., Larsen, J. M., Thomsen, K. K., Lindhardt, T. B., Böttcher, M., Molsted, S., Havndrup, O., Fischer, T., Møller, D. S., Henriksen, F. L., Johansen, J. B., Nielsen, J. C., Bundgaard, H. ... Jensen, H. K. (2022). Diagnostic Yield of Genetic Testing in Young Patients With Atrioventricular Block of Unknown Cause. Journal of the American Heart Association, 11(9), Article e025643. https://doi.org/10.1161/JAHA.121.025643

Svendsen, S. L., Kornvig, S., Berg, P., Jensen, I. S., de Araujo, I. B. B. A., Larsen, C. K., Leipziger, J. & Sorensen, M. V. (2022). Dietary K⁺ acts as a genuine diuretic. Acta Physiologica, 234(2), Article e13762. https://doi.org/10.1111/apha.13762

Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B. ... Demontis, D. (2022). Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder. Nature Genetics, 54(8), 1117-1124. https://doi.org/10.1038/s41588-022-01143-7

Frøbert, A. M., Toews, J. N. C., Nielsen, C. G., Brohus, M., Kindberg, J., Jessen, N., Fröbert, O., Hammond, G. L. & Overgaard, M. T. (2022). Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats. Physiological and Biochemical Zoology, 95(5), 365-378. https://doi.org/10.1086/721154

Liu, C. C., Kim, Y. J., Teh, R., Garcia, A., Hamilton, E. J., Cornelius, F., Baxter, R. C. & Rasmussen, H. H. (2022). Displacement of Native FXYD Protein From Na⁺/K⁺-ATPase With Novel FXYD Peptide Derivatives: Effects on Doxorubicin Cytotoxicity. Frontiers in Oncology, 12, Article 859216. https://doi.org/10.3389/fonc.2022.859216

Kristensen, M., Fenton, R. A. & Poulsen, S. B. (2022). Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na+ Channel and the NaCl Cotransporter. Frontiers in Physiology, 13, Article 800055. https://doi.org/10.3389/fphys.2022.800055

Mullins, N., Kang, J., Campos, A., Coleman, J. R., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M.-H., Watson, H. J., Adams, M., Awasthi, S., Ganda, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S. ... VA Million Vet Program (2022). Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry, 91(3), 313-327. https://doi.org/10.1016/j.biopsych.2021.05.029

Bromer, F. D., Brent, M. B., Thomsen, J. S. & Bruel, A. (2022). Drill-Hole Bone Defects in Animal Models of Bone Healing: Protocol for a Systematic Review. JMIR Research Protocols, 11(7), Article e34887. https://doi.org/10.2196/34887

Koch, E. & Demontis, D. (2022). Drug repurposing candidates to treat core symptoms in autism spectrum disorder. Frontiers in Pharmacology, 13, Article 995439. https://doi.org/10.3389/fphar.2022.995439

Van Der Horst, J., Rognant, S., Hellsten, Y., Aalkjær, C. & Jepps, T. A. (2022). Dynein Coordinates β2-Adrenoceptor-Mediated Relaxation in Normotensive and Hypertensive Rat Mesenteric Arteries. Hypertension, 79(10), 2214-2227. https://doi.org/10.1161/HYPERTENSIONAHA.122.19351

Wimberley, T., Brikell, I., Pedersen, E. M., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Privé, F., Thapar, A., Langley, K., Riglin, L., Simonsen, M., Nielsen, H. S., Børglum, A. D., Nordentoft, M., Mortensen, P. B. & Dalsgaard, S. (2022). Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychiatry, 83(1), Article 21m14033. https://doi.org/10.4088/JCP.21m14033

Skejø, C., Vestergaard, T. & Julsgaard, M. (2022). Editorial: safety of ustekinumab in pregnancy-are we there yet? Alimentary Pharmacology and Therapeutics, 55(4), 495-496. https://doi.org/10.1111/apt.16767

Zhang, S., Jiang, H. & Wu, Q. (2022). Editorial: Exploring the subcellular proteome and its post-translational modifications. Frontiers in Molecular Biosciences, 9, Article 994961. https://doi.org/10.3389/fmolb.2022.994961

Brent, M. B., Simonsen, U., Thomsen, J. S. & Brüel, A. (2022). Effect of Acetazolamide and Zoledronate on Simulated High Altitude-Induced Bone Loss. Frontiers in Endocrinology, 13, Article 831369. https://doi.org/10.3389/fendo.2022.831369

Vestergaard, S. V., Heide-Jørgensen, U., Birn, H. & Christiansen, C. F. (2022). Effect of the Refitted Race-Free eGFR Formula on the CKD Prevalence and Mortality in the Danish Population. Clinical Journal of American Society of Nephrology. , 17(3), 426-428. https://doi.org/10.2215/CJN.14491121

Lauritsen, K. M., Voigt, J. H., Pedersen, S. B., Hansen, T. K., Møller, N., Jessen, N., Gormsen, L. C. & Søndergaard, E. (2022). Effects of SGLT2 inhibition on lipid transport in adipose tissue in type 2 diabetes. Endocrine Connections, 11(4), Article e210558. https://doi.org/10.1530/EC-21-0558

ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group (2022). Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial. The Lancet Infectious Diseases, 22(5), 622-635. https://doi.org/10.1016/S1473-3099(21)00751-9

Porpiglia, E., Mai, T., Kraft, P., Holbrook, C. A., de Morree, A., Gonzalez, V. D., Hilgendorf, K. I., Frésard, L., Trejo, A., Bhimaraju, S., Jackson, P. K., Fantl, W. J. & Blau, H. M. (2022). Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. Cell Stem Cell, 29(12), 1653-1668.e8. https://doi.org/10.1016/j.stem.2022.10.009

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature Communications, 13(1), Article 3620. https://doi.org/10.1038/s41467-022-31388-z

Xue, J., Thomas, L., Murali, S. K., Levi, M., Fenton, R. A., Dominguez Rieg, J. A. & Rieg, T. (2022). Enhanced phosphate absorption in intestinal epithelial cell-specific NHE3 knockout mice. Acta Physiologica (Print), 234(2), Article e13756. https://doi.org/10.1111/apha.13756

Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E. ... Nievergelt, C. M. (2022). Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biological Psychiatry, 91(7), 626-636. https://doi.org/10.1016/j.biopsych.2021.09.020

Bińkowski, J., Taryma-Leśniak, O., Łuczkowska, K., Niedzwiedź, A., Lechowicz, K., Strapagiel, D., Jarczak, J., Davalos, V., Pujol, A., Esteller, M., Kotfis, K., Machaliński, B., Parczewski, M. & Wojdacz, T. K. (2022). Epigenetic activation of antiviral sensors and effectors of interferon response pathways during SARS-CoV-2 infection. Biomedicine and Pharmacotherapy, 153, Article 113396. https://doi.org/10.1016/j.biopha.2022.113396

Kresse, J.-C., Mutsaers, H. A. M., Jensen, M. S., Tingskov, S. J., Gebauer Madsen, M., Nejsum, L. N., Prætorius Øhrwald, H. & Nørregaard, R. (2022). EP₁ receptor antagonism mitigates early and late stage renal fibrosis. Acta Physiologica (Print), 234(3), Article e13780. https://doi.org/10.1111/apha.13780

Comerma Steffensen, S. G., Prat Duran, J., Mogensen, S., Sobrano Fais, R., Pinilla, E. & Simonsen, U. (2022). Erectile Dysfunction and Altered Contribution of KCa1.1 and KCa2.3 Channels in the Penile Tissue of Type-2 Diabetic db/db Mice. Journal of Sexual Medicine, 19(5), 697-710. https://doi.org/10.1016/j.jsxm.2022.02.021

DBDS Genomic Consortium (2022). Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: A Danish genome-wide association study. Joint Bone Spine, 89(4), Article 105357. https://doi.org/10.1016/j.jbspin.2022.105357