Peer-reviewed publications

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Lopes-Rodrigues, V., Boxy, P., Sim, E., Park, D. I., Habeck, M., Carbonell, J., Andersson, A., Fernández-Suárez, D., Nissen, P., Nykjær, A. & Kisiswa, L. (2023). AraC interacts with p75^NTR transmembrane domain to induce cell death of mature neurons. Cell Death and Disease, 14(7), Article 440. https://doi.org/10.1038/s41419-023-05979-7

Einer, C., Munk, D. E., Park, E., Akdogan, B., Nagel, J., Lichtmannegger, J., Eberhagen, C., Rieder, T., Vendelbo, M. H., Michalke, B., Wimmer, R., Blutke, A., Feuchtinger, A., Dershwitz, P., DiSpirito, A. M., Islam, T., Castro, R. E., Min, B. K., Kim, T. W. ... Zischka, H. (2023). ARBM101 (Methanobactin SB2) Drains Excess Liver Copper via Biliary Excretion in Wilson's Disease Rats. Gastroenterology, 165(1), 187-200.e7. https://doi.org/10.1053/j.gastro.2023.03.216

Thunbo, M. Ø., Vendelbo, J. H., Witte, D. R., Larsen, A. & Pedersen, L. H. (2023). A rising tide of polypharmacy in pregnancy: The use of one or multiple prescription drugs in pregnancy in Denmark 1998-2018. Abstract from European Perinatal and Pediatric Epidemiology Conference (EPEC) 2023, Stockholm, Sweden.

The COVID-19 Host Genetics Initiative (2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621(7977), E7-E26. https://doi.org/10.1038/s41586-023-06355-3

Ghavami, M., Pedersen, J. G., Kjeldsen, R. B., Alstrup, A. K. O., Zhang, Z., Koulianou, V., Palmfeldt, J., Vorup-Jensen, T., Thamdrup, L. H. E. & Boisen, A. (2023). A self-unfolding proximity enabling device for oral delivery of macromolecules. Journal of Controlled Release, 361, 40-52. https://doi.org/10.1016/j.jconrel.2023.07.041

Yilmaz, Z., Quattlebaum, M. J., Pawar, P. S., Thornton, L. M., Bulik, C. M., Javaras, K. N., Yao, S., Lichtenstein, P., Larsson, H. & Baker, J. H. (2023). Associations Between Attention Deficit Hyperactivity Disorder Symptom Dimensions and Disordered Eating Symptoms in Adolescence: A Population-Based Twin Study. Behavior Genetics, 53(2), 143-153. https://doi.org/10.1007/s10519-022-10128-5

Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, T. & Ingason, A. (2023). Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study. The Lancet Psychiatry, 10(2), 129-138. https://doi.org/10.1016/S2215-0366(23)00004-4

Kim, D. W. & Blackshaw, S. (2023). A super Sonic circadian synchronizer. Science (New York, N.Y.), 380(6648), 896-897. https://doi.org/10.1126/science.adi3177

Sahana, U., Wehland, M., Simonsen, U., Schulz, H. & Grimm, D. (2023). A Systematic Review of the Effect of Vericiguat on Patients with Heart Failure. International Journal of Molecular Sciences , 24(14), Article 11826. https://doi.org/10.3390/ijms241411826

Chumpen Ramirez, S., Gómez-Sánchez, R., Verlhac, P., Hardenberg, R., Margheritis, E., Cosentino, K., Reggiori, F. & Ungermann, C. (2023). Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy. Autophagy, 19(5), 1459-1478. https://doi.org/10.1080/15548627.2022.2136340

Thygesen, M., Entezari, S., Houlind, N. K., Nielsen, T. H., Olsen, N. Ø., Skov, M., Nielsen, T. D., Tankisi, A., Rasmussen, M., Einarsson, H. B., Agger, P., Orlowski, D., Dyrskog, S. E., Thorup, L., Pedersen, M. & Rasmussen, M. M. (2023). A traumatic spinal cord injury critical care porcine model. Abstract from Eurospine 2023.

Kristensen, S. E., Gadsbøll, K., Nicolaides, K. H., Vogel, I., Pedersen, L. H., Wright, A., Petersen, O. B. & Wright, D. (2023). Atypicality index: avoiding false reassurance in prenatal screening. Ultrasound in Obstetrics & Gynecology, 61(3), 333-338. https://doi.org/10.1002/uog.26135

Rajanathan, R., Pedersen, T. M., Guldbrandsen, H. O., Olesen, L. F., Thomsen, M. B., Bøtker, H. E. & Matchkov, V. V. (2023). Augmented Ouabain-Induced Vascular Response Reduces Cardiac Efficiency in Mice with Migraine-Associated Mutation in the Na⁺, K⁺-ATPase α₂-Isoform. Biomedicines, 11(2), Article 344. https://doi.org/10.3390/biomedicines11020344

ADHD Working Group of the Psychiatric Genomics Consortium (2023). Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics, 55(4), 730. https://doi.org/10.1038/s41588-023-01350-w

Vanker, M., Särekannu, K., Fekkar, A., Jørgensen, S. E., Haljasmägi, L., Kallaste, A., Kisand, K., Lember, M., Peterson, P., Menon, M., Hussell, T., Knight, S., Moore-Stanley, J., Bastard, P., Zhang, S. Y., Mogensen, T. H., Philippot, Q., Zhang, Q., Puel, A. ... Kisand, K. (2023). Autoantibodies Neutralizing Type III Interferons Are Uncommon in Patients with Severe Coronavirus Disease 2019 Pneumonia. Journal of Interferon & Cytokine Research, 43(9), 379-393. https://doi.org/10.1089/jir.2023.0003

Rasmussen, E. B., Thiele, L. S., Stengaard-Pedersen, K., Hetland, M. L., Hørslev-Petersen, K., Junker, P., Østergaard, M., Hansen, A. S., Hvid, M., Deleuran, B. & Greisen, S. R. (2023). Baseline serum levels of IgA anti-cyclic citrullinated protein antibodies in early rheumatoid arthritis predict radiographic progression after 11 years of treatment: a secondary analysis of the CIMESTRA study. Scandinavian Journal of Rheumatology, 52(5), 493-497. https://doi.org/10.1080/03009742.2022.2127245

Wibrand, C., Wittenborn, T. R., Voss, L. F., Winther, G., Jensen, L., Ferapontov, A., Fonager, S. V., Fahlquist-Hagert, C. & Degn, S. E. (2023). B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus. Frontiers in Immunology, 14, Article 1258046. https://doi.org/10.3389/fimmu.2023.1258046

Tveden-Nyborg, P., Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, J. (2023). BCPT 2023 policy for experimental and clinical studies. Basic and Clinical Pharmacology and Toxicology, 133(4), 391-396. https://doi.org/10.1111/bcpt.13944

Jeyaseelan, T., Romero-Ramos, M. & Petersen, C. C. (2023). Betrayal of the Markers. Cytometry. Part A, 103(9), 692-694. https://doi.org/10.1002/cyto.a.24781

Friis, S. J., Hansen, T. S., Poulsen, M., Gregersen, H., Brüel, A. & Vinge Nygaard, J. (2023). Biomechanical properties of the stomach: A comprehensive comparative analysis of human and porcine gastric tissue. Journal of the Mechanical Behavior of Biomedical Materials, 138, Article 105614. https://doi.org/10.1016/j.jmbbm.2022.105614

Pedersen, D. V., Gytz, H., Winkler, M. B. L., Zarantonello, A., Baumann, N., Hansen, A. G., Thiel, S., Andersen, G. R., Valerius, T. & Laursen, N. S. (2023). Bispecific Complement Engagers for Targeted Complement Activation. Journal of Immunology, 211(3), 403-413. https://doi.org/10.4049/jimmunol.2200952

Huysseune, A., Larsen, U. G., Larionova, D., Matthiesen, C. L., Petersen, S. V., Muller, M. & Witten, P. E. (2023). Bone Formation in Zebrafish: The Significance of DAF-FM DA Staining for Nitric Oxide Detection. Biomolecules, 13(12), Article 1780. https://doi.org/10.3390/biom13121780

Jordt, N., Kjærgaard, K. A., Thomsen, R. W., Borgquist, S. & Cronin-Fenton, D. (2023). Breast cancer and incidence of type 2 diabetes mellitus: a systematic review and meta-analysis. Breast Cancer Research and Treatment, 202(1), 11-22. https://doi.org/10.1007/s10549-023-07043-6, https://doi.org/10.1007/s10549-023-07043-6

Boxy, P., Nykjær, A. & Kisiswa, L. (2023). Building better brains: the pleiotropic function of neurotrophic factors in postnatal cerebellar development. Frontiers in Molecular Neuroscience, 16, Article 1181397. https://doi.org/10.3389/fnmol.2023.1181397

Højer Wang, L., Wehland, M., Wise, P. M., Infanger, M., Grimm, D. & Kreissl, M. C. (2023). Cabozantinib, Vandetanib, Pralsetinib and Selpercatinib as Treatment for Progressed Medullary Thyroid Cancer with a Main Focus on Hypertension as Adverse Effect. International Journal of Molecular Sciences , 24(3), Article 2312. https://doi.org/10.3390/ijms24032312

Hansen, J. S., Gustavsen, S., Roshanisefat, H., Kant, M., Biering-Sørensen, F., Andersen, C., Olsson, A., Chow, H. H., Asgari, N., Richter Hansen, J., Nielsen, H. H., Hansen, R. M., Petersen, T., Oturai, A. B., Sellebjerg, F. T., Sædder, E. A., Kasch, H., Rasmussen, P. V., Finnerup, N. B. & Svendsen, K. B. (2023). Cannabis-Based Medicine for Neuropathic Pain and Spasticity-A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial. Pharmaceuticals, 16(8), Article 1079. https://doi.org/10.3390/ph16081079

Lee, S., Toft, N. J., Axelsen, T. V., Espejo, M. S., Pedersen, T. M., Mele, M., Pedersen, H. L., Balling, E., Johansen, T., Burton, M., Thomassen, M., Vahl, P., Christiansen, P. M. & Boedtkjer, E. (2023). Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer. Breast Cancer Research, 25(1), Article 46. https://doi.org/10.1186/s13058-023-01644-1

Liu, B., Chen, R., Zhang, Y., Huang, J., Luo, Y., Rosthøj, S., Zhao, C. & Jäättelä, M. (2023). Cationic amphiphilic antihistamines inhibit STAT3 via Ca²⁺-dependent lysosomal H⁺ efflux. Cell Reports, 42(2), Article 112137. https://doi.org/10.1016/j.celrep.2023.112137

He, M., Roussak, K., Ma, F., Borcherding, N., Garin, V., White, M., Schutt, C., Jensen, T. I., Zhao, Y., Iberg, C. A., Shah, K., Bhatia, H., Korenfeld, D., Dinkel, S., Gray, J., Ulezko Antonova, A., Ferris, S., Donermeyer, D., Lindestam Arlehamn, C. ... Klechevsky, E. (2023). CD5 expression by dendritic cells directs T cell immunity and sustains immunotherapy responses. Science, 379(6633), Article eabg2752. https://doi.org/10.1126/science.abg2752

Månsson, C. T., Meldgaard, P., Stougaard, M., Nielsen, A. L. & Sørensen, B. S. (2023). Cell-free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients. Molecular Oncology, 17(5), 722-736. https://doi.org/10.1002/1878-0261.13394

Tse, D., Privitera, L., Norton, A. C., Gobbo, F., Spooner, P., Takeuchi, T., Martin, S. J. & Morris, R. G. M. (2023). Cell-type-specific optogenetic stimulation of the locus coeruleus induces slow-onset potentiation and enhances everyday memory in rats. Proceedings of the National Academy of Sciences (PNAS), 120(46), Article e2307275120. https://doi.org/10.1073/pnas.2307275120

Accelerating Medicines Partnership (AMP): RA/SLE, Zhang, F., Raychaudhuri, S., Brenner, M., Buckley, C., Thyagarajan, M., Accelerating Medicines Partnership Program RA SLE Network, Shiekh, Z., Compeyrot-Lacassagne, S., Chippington, S., Coles, M., Al-Abadi, E., Filer, A., Tissue Research in Childhood Onset Inflammatory Arthritis (TRICIA) Consortium, R Wedderburn, L. & Croft, A. (2023). Cellular Deconstruction of Stromal and Myeloid Cell Compartments in the Inflamed Synovium of Juvenile Idiopathic Arthritis. Abstract from ACR Convergence 2023, San Diego, California, United States. https://acrabstracts.org/abstract/cellular-deconstruction-of-stromal-and-myeloid-cell-compartments-in-the-inflamed-synovium-of-juvenile-idiopathic-arthritis/

Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Brodin, B. (2023). Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line. Fluids and Barriers of the CNS, 20(1), Article 96. https://doi.org/10.1186/s12987-023-00501-9

Walker, M. R., Idorn, M., Bennett, A., Søgaard, M., Salanti, A., Ditlev, S. B. & Barfod, L. (2023). Characterization of SARS-CoV-2 humoral immune response in a subject with unique sampling: A case report. Immunity, Inflammation and Disease, 11(6), Article e910. https://doi.org/10.1002/iid3.910

Simonsen, U. & Lykkesfeldt, J. (2023). Charting a new course: A vision for the future as editors-in-chief. Basic and Clinical Pharmacology and Toxicology, 133(4), 390. https://doi.org/10.1111/bcpt.13942

Ieamviteevanich, P., Daneshvar, E., Pinitsoontorn, S., Hazrati, H., Ding, L. & Bhatnagar, A. (2023). Chemical-free fabrication of carbon fiber aerogels from egg boxes for the removal of pharmaceutically active compounds in aqueous solution. Journal of Water Process Engineering, 53, Article 103801. https://doi.org/10.1016/j.jwpe.2023.103801

Okkels, N., Horsager, J., Pavese, N., Brooks, D. J. & Borghammer, P. (2023). Cholinergic Imaging and Dementia. In Molecular Imaging of Neurodegenerative Disorders (pp. 127-144). Springer International Publishing. https://doi.org/10.1007/978-3-031-35098-6_8

Bingham, M. A., Neijman, K., Yang, C. R., Aponte, A., Mak, A., Kikuchi, H., Jung, H. J., Poll, B. G., Raghuram, V., Park, E., Chou, C. L., Chen, L., Leipziger, J., Knepper, M. A. & Dona, M. (2023). Circadian gene expression in mouse renal proximal tubule. American Journal of Physiology: Renal Physiology, 324(3), F301-F314. https://doi.org/10.1152/ajprenal.00231.2022

Tolomeo, D., Traversa, D., Venuto, S., Ebbesen, K., Garcia Rodriguez, J. L., Tamma, G., Ranieri, M., Simonetti, G., Ghetti, M., Paganelli, M., Visci, G., Liso, A., Kok, K., Muscarella, L. A., Fabrizio, F. P., Frassanito, M. A., Lamanuzzi, A., Saltarella, I., Solimando, A. G. ... Storlazzi, C. T. (2023). circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in Small Cell Lung Cancer. Genes, Chromosomes & Cancer, 62(7), 377-391. https://doi.org/10.1002/gcc.23121

Jeppesen, L. D., Hatt, L., Singh, R., Schelde, P., Ravn, K., Toft, C. L., Laursen, M. B., Hedegaard, J., Christensen, I. B., Nicolaisen, B. H., Andreasen, L., Pedersen, L. H., Vogel, I. & Lildballe, D. L. (2023). Clinical interpretation of cell-based non-invasive prenatal testing for monogenic disorders including repeat expansion disorders: potentials and pitfalls. Frontiers in Genetics, 14, Article 1188472. https://doi.org/10.3389/fgene.2023.1188472

Wang, R., Singaraju, A., Marks, K. E., Shakib, L., Dunlap, G., Adejoorin, I., Greisen, S. R., Chen, L., Tirpack, A. K., Aude, C., Fein, M. R., Todd, D. J., MacFarlane, L., Goodman, S. M., DiCarlo, E. F., Massarotti, E. M., Sparks, J. A., Jonsson, A. H., Brenner, M. B. ... Rao, D. A. (2023). Clonally expanded CD38^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis. Science Immunology, 8(85), Article eadd1591. https://doi.org/10.1126/sciimmunol.add1591

Ehlers, T. S., van der Horst, J., Møller, S., Piil, P. K., Gliemann, L., Aalkjær, C., Jepps, T. A. & Hellsten, Y. (2023). Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension. British Journal of Clinical Pharmacology, 89(7), 2179-2189. https://doi.org/10.1111/bcp.15688

Krogager, M. E., Dahl, R. H., Poulsgaard, L., Fugleholm, K., Sehested, T., Mikkelsen, R., Tranum-Jensen, J., Mathiesen, T. I. & Benndorf, G. (2023). Combined cone-beam CT imaging and microsurgical dissection of cadaver specimens to study cerebral venous anatomy: a technical note. Surgical and Radiologic Anatomy, 45(9), 1177-1184. https://doi.org/10.1007/s00276-023-03195-8

Andersen, F. D., Steffensen, S. C., Vistisen, S. T., Pinilla, E., Pedersen, T. M., Matchkov, V., Simonsen, U. & Andersen, C. U. (2023). Combined effects of methadone and quetiapine on respiratory rate, haemodynamic variables, and temperature in conscious rats. Addiction Biology, 28(9), Article e13320. https://doi.org/10.1111/adb.13320

Galdos, F. X., Lee, C., Lee, S., Paige, S., Goodyer, W., Xu, S., Samad, T., Escobar, G. V., Darsha, A., Beck, A., Bak, R. O., Porteus, M. H. & Wu, S. M. (2023). Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation. eLife, 12, Article e80075. https://doi.org/10.7554/eLife.80075

Møller, P. L., Rohde, P. D., Dahl, J. N., Rasmussen, L. D., Schmidt, S. E., Nissen, L., McGilligan, V., Bentzon, J. F., Gudbjartsson, D. F., Stefansson, K., Holm, H., Winther, S., Bøttcher, M. & Nyegaard, M. (2023). Combining Polygenic and Proteomic Risk Scores With Clinical Risk Factors to Improve Performance for Diagnosing Absence of Coronary Artery Disease in Patients With De Novo Chest Pain. Circulation: Genomic and Precision Medicine, 16(5), 442-451. Article e004053. https://doi.org/10.1161/CIRCGEN.123.004053

Vestergaard, S. V., Ulrichsen, S. P., Dahl, C. M., Marcussen, T. & Christiansen, C. F. (2023). Comorbidity, Criminality, and Costs of Patients Treated for Gambling Disorder in Denmark. Journal of Gambling Studies, 39(4), 1765-1780. https://doi.org/10.1007/s10899-023-10255-6

Nielsen, S. Y., Murra, M., Pedersen, L. H., Khalil, M. R., Hvidman, L., Helmig, R. B., Møller, J. K., Kirkeby, M., Rosbjerg, A.-M. & Henriksen, T. B. (2023). Comparatively low rates of COVID-19 in women admitted in labor and their newborns prior to routine vaccination of pregnant women: insights from Denmark. The Journal of Maternal-Fetal & Neonatal Medicine, 36(2), Article 2229933. https://doi.org/10.1080/14767058.2023.2229933

Antonsen, K. W., Friis, H. N., Sorensen, B. S., Etzerodt, A., Moestrup, S. K. & Møller, H. J. (2023). Comparison of culture media reveals that non-essential amino acids strongly affect the phenotype of human monocyte-derived macrophages. Immunology, 170(3), 344-358. https://doi.org/10.1111/imm.13670

Zhao, X., Qu, K., Curci, B., Yang, H., Bolund, L., Lin, L. & Luo, Y. (2023). Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations. Biomolecules, 13(5), Article 870. https://doi.org/10.3390/biom13050870

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