Peer-reviewed publications

Peer-reviewed publications

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Emmanuel, T., Ignatov, B., Bertelsen, T., Litman, T., Nielsen, M. M., Brent, M. B., Touborg, T., Rønsholdt, A. B., Petersen, A., Boye, M., Kaaber, I., Sortebech, D., Lybæk, D., Steiniche, T., Bregnhøj, A., Eidsmo, L., Iversen, L. & Johansen, C. (2024). Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory. International Journal of Molecular Sciences , 25(11), Article 6086. https://doi.org/10.3390/ijms25116086
Becker, B., Wottawa, F., Bakr, M., Koncina, E., Mayr, L., Kugler, J., Yang, G., Windross, S. J., Neises, L., Mishra, N., Harris, D., Tran, F., Welz, L., Schwärzler, J., Bánki, Z., Stengel, S. T., Ito, G., Krötz, C., Coleman, O. I. ... Aden, K. (2024). Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut. iScience, 27(3), Article 109173. https://doi.org/10.1016/j.isci.2024.109173
Yang, Y., Fang, F., Arnberg, F. K., Kuja-Halkola, R., D'Onofrio, B. M., Larsson, H., Brikell, I., Chang, Z., Andreassen, O. A., Lichtenstein, P., Valdimarsdóttir, U. A. & Lu, D. (2024). Sex differences in clinically diagnosed psychiatric disorders over the lifespan: a nationwide register-based study in Sweden. The Lancet Regional Health - Europe, 47, Article 101105. https://doi.org/10.1016/j.lanepe.2024.101105
Pisanu, C., Congiu, D., Meloni, A., Paribello, P., Severino, G., Ardau, R., Chillotti, C., Als, T. D., Børglum, A. D., Del Zompo, M., Manchia, M. & Squassina, A. (2024). Sex differences in shared genetic determinants between severe mental disorders and metabolic traits. Psychiatry Research, 342, Article 116195. https://doi.org/10.1016/j.psychres.2024.116195
Al-Diab, O., Sünkel, C., Blanc, E., Catar, R. A., Ashraf, M. I., Zhao, H., Wang, P., Rinschen, M. M., Fritsche-Guenther, R., Grahammer, F., Bachmann, S., Beule, D., Kirwan, J. A., Rajewsky, N., Huber, T. B., Gürgen, D. & Kusch, A. (2024). Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin. Biology of Sex Differences, 15(1), 72. Article 72. https://doi.org/10.1186/s13293-024-00647-7
Qi, B., Graff, M., Bulik, C. M., North, K. E., Munn-Chernoff, M. A. & Grove, J. (2024). Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome-wide association studies. Brain and Behavior, 14(2), e3294. Article e3294. https://doi.org/10.1002/brb3.3294
Nielsen, T. T., Duan, J., Levey, D. F., Walters, G. B., Johnson, E. C., Thorgeirsson, T., Werge, T., Mortensen, P. B., Stefansson, H., Stefansson, K., Hougaard, D. M., Agrawal, A., Gelernter, J., Grove, J., Børglum, A. & Demontis, D. (2024). Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD. Nature Mental Health, 2(9), 1071-1083. Article 108535. https://doi.org/10.1038/s44220-024-00277-3
Bucheli, O. T. M., Rodrigues, D., Portmann, K., Linder, A., Thoma, M., Halin, C. & Eyer, K. (2024). Single-B cell analysis correlates high-lactate secretion with stress and increased apoptosis. Scientific Reports, 14(1), 8507. Article 8507. https://doi.org/10.1038/s41598-024-58868-0
Cham, L. B., Rosas-Umbert, M., Lin, L., Tolstrup, M. & Søgaard, O. S. (2024). Single-Cell Analysis Reveals That CD47 mRNA Expression Correlates with Immune Cell Activation, Antiviral Isgs, and Cytotoxicity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 58(4), 322-335. https://doi.org/10.33594/000000715
Wälchli, T., Ghobrial, M., Schwab, M., Takada, S., Zhong, H., Suntharalingham, S., Vetiska, S., Gonzalez, D. R., Wu, R., Rehrauer, H., Dinesh, A., Yu, K., Chen, E. L. Y., Bisschop, J., Farnhammer, F., Mansur, A., Kalucka, J., Tirosh, I., Regli, L. ... Radovanovic, I. (2024). Single-cell atlas of the human brain vasculature across development, adulthood and disease. Nature, 632(8025), 603-613. https://doi.org/10.1038/s41586-024-07493-y
Wang, C., Zhang, B., Cong, Y., Du, X., Chen, S., Visser, L., Ruiz-Moreno, A., Zhang, L., Reggiori, F., Alexander, D. & Groves, M. R. (2024). Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells. ChemMedChem, 19(13), e202300688. Article e202300688. https://doi.org/10.1002/cmdc.202300688
Stefanucci, L., Moslemi, C., Tomé, A. R., Virtue, S., Bidault, G., Gleadall, N. S., Watson, L. P. E., Kwa, J. E., Burden, F., Farrow, S., Banasik, K., Bay, J., Boldsen, J. K., Brodersen, T., Brunak, S., Burgdorf, K., Chalmer, M. A., Didriksen, M., Dinh, K. M. ... Frontini, M. (2024). SMIM1 absence is associated with reduced energy expenditure and excess weight. Med, 5(9), 1083-1095.e6. https://doi.org/10.1016/j.medj.2024.05.015
Kaminska, P., Ovesen, P. L., Jakiel, M., Obrebski, T., Schmidt, V., Draminski, M., Bilska, A. G., Bieniek, M., Anink, J., Paterczyk, B., Jensen, A. M. G., Piatek, S., Andersen, O. M., Aronica, E., Willnow, T. E., Kaminska, B., Dabrowski, M. J. & Malik, A. R. (2024). SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment. EMBO Reports, 25(5), 2278-2305. https://doi.org/10.1038/s44319-024-00117-6
Orr, M. E., Kulasinghe, A., Kolar, G. R., Heyn, H., Plummer, J., Sommer Kristensen, L., Kjems, J., Mills, G., Garcia-Vallejo, J. J., Nijman, I. J., West, N. P. & Cox, A. (2024). Sounding an Alarm over Spatial Biology. Genetic Engineering and Biotechnology News, 44(3), 16-17. https://doi.org/10.1089/gen.44.03.07
Lemaitre, L., Adeniji, N., Suresh, A., Reguram, R., Zhang, J., Park, J., Reddy, A., Trevino, A. E., Mayer, A. T., Deutzmann, A., Hansen, A. S., Tong, L., Arjunan, V., Kambham, N., Visser, B. C., Dua, M. M., Bonham, C. A., Kothary, N., D’Angio, H. B. ... Dhanasekaran, R. (2024). Spatial analysis reveals targetable macrophage-mediated mechanisms of immune evasion in hepatocellular carcinoma minimal residual disease. Nature Cancer, 5(10), 1534-1556. https://doi.org/10.1038/s43018-024-00828-8
Jansen, N. A., Linnenbank, C., Schenke, M., Voskuyl, R. A., Jorge, M. S., Krivoshein, G., Breukel, C., Linssen, M. M., Claassens, J. W. C., Brouwers, C., van Heiningen, S. H., Heuck, A., Lykke-Hartmann, K., Tolner, E. A. & van den Maagdenberg, A. M. J. M. (2024). Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2. Neurobiology of Disease, 202, Article 106714. https://doi.org/10.1016/j.nbd.2024.106714
Steinwerth, P., Bertrand, J., Sandt, V., Marchal, S., Sahana, J., Bollmann, M., Schulz, H., Kopp, S., Grimm, D. & Wehland, M. (2024). Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor. Biomolecules, 14(1), Article 25. https://doi.org/10.3390/biom14010025
Liekniņa, I., Reimer, L., Panteļejevs, T., Lends, A., Jaudzems, K., El-Turabi, A., Gram, H., Hammi, A., Jensen, P. H. & Tārs, K. (2024). Structural basis of epitope recognition by anti-alpha-synuclein antibodies MJFR14-6-4-2. npj Parkinson's Disease , 10(1), Article 206. https://doi.org/10.1038/s41531-024-00822-y
Qin, Y., Poulsen, C., Narayanan, D., Chan, C. B., Chen, X., Montes, B. R., Tran, K. T., Mukminova, E., Lin, C., Gajhede, M., Bullock, A. N., Olagnier, D. & Bach, A. (2024). Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors. Journal of Medicinal Chemistry, 67(21), 18828-18864. https://doi.org/10.1021/acs.jmedchem.4c01221
Holst Hansen, K., Byeon, C. H., Liu, Q., Drace, T., Boesen, T., Conway, J. F., Andreasen, M. & Akbey, Ü. (2024). Structure of biofilm-forming functional amyloid PSMα1 from Staphylococcus aureus. Proceedings of the National Academy of Sciences (PNAS), 121(33), Article e2406775121. https://doi.org/10.1073/pnas.2406775121
Thunbo, M. Ø., Hulman, A., Witte, D. R., Liew, Z. & Pedersen, L. H. (2024). SuperLearner based prediction of fetal growth restriction in a Danish national birth cohort. Abstract from NorPEN (Nordic PharmacoEpidemiological Network) 16th Annual meeting, Copenhagen, Denmark.
Dear, A. J., Meisl, G., Taylor, C. G., Palmiero, U. C., Stubbe, S. N., Liu, Q., Arosio, P., Linse, S., Knowles, T. P. J. & Andreasen, M. (2024). Surface effects on functional amyloid formation. Nanoscale, 16(34), 16172-16182. https://doi.org/10.1039/d4nr01496k
Comini, G., Kelly, R., Jarrin, S., Patton, T., Narasimhan, K., Pandit, A., Drummond, N., Kunath, T. & Dowd, E. (2024). Survival and maturation of human induced pluripotent stem cell-derived dopaminergic progenitors in the parkinsonian rat brain is enhanced by transplantation in a neurotrophin-enriched hydrogel. Journal of Neural Engineering, 21(2), Article 024002. https://doi.org/10.1088/1741-2552/ad33b2
Lunding, B. S., Bassi, M. R., Christensen, J. P., Thomsen, A. R., Sørensen, T. L., Vorum, H., Honoré, B., Nissen, M. H. & Steffensen, M. A. (2024). Systemic infection in aged mice causes upregulation of crystallin alpha A in the RPE/choroid. Experimental Eye Research, 245, Article 109984. https://doi.org/10.1016/j.exer.2024.109984
Bendstrup, E., Lynn, E. & Troldborg, A. (2024). Systemic Lupus Erythematosus-related Lung Disease. Seminars in Respiratory and Critical Care Medicine, 45(3), 386-396. https://doi.org/10.1055/s-0044-1782653
Daskalakis, N. P., Iatrou, A., Chatzinakos, C., Jajoo, A., Snijders, C., Wylie, D., DiPietro, C. P., Tsatsani, I., Chen, C.-Y., Pernia, C. D., Soliva-Estruch, M., Arasappan, D., Bharadwaj, R. A., Collado-Torres, L., Wuchty, S., Alvarez, V. E., Dammer, E. B., Deep-Soboslay, A., Duong, D. M. ... PTSD Working Group of Psychiatric Genomics Consortium** (2024). Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science, 384(6698), Article eadh3707. https://doi.org/10.1126/science.adh3707
Yuan, X., Ruan, W., Bobrow, B., Carmeliet, P. & Eltzschig, H. K. (2024). Targeting hypoxia-inducible factors: therapeutic opportunities and challenges. Nature Reviews Drug Discovery, 23(3), 175-200. https://doi.org/10.1038/s41573-023-00848-6
Unal, B., Kuzu, O. F., Jin, Y., Osorio, D., Kildal, W., Pradhan, M., Kung, S. H. Y., Oo, H. Z., Daugaard, M., Vendelbo, M., Patterson, J. B., Thomsen, M. K., Kuijjer, M. L. & Saatcioglu, F. (2024). Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer. Nature Communications, 15(1), Article 8895. https://doi.org/10.1038/s41467-024-53039-1
Muttuvelu, D. V., Cehofski, L. J., Utheim, T. P., Chen, X., Vorum, H., Rasmussen, M. L. R., Heegaard, S., Khan, A. M., Abduljabar, A. B. & Honoré, B. (2024). Tear film proteome changes following Tobradex® therapy in anterior blepharitis. Acta Ophthalmologica, 102(4), e565-e576. https://doi.org/10.1111/aos.15792
Younoussa, H., Gadji, M., Soumboundou, M., Colicchio, B., Said, A., Ndoye, N. A., Junker, S., Plesch, A., Heidingsfelder, L., Diagne, N. R., Dieterlen, A., Voisin, P., Carde, P., Jeandidier, E. & M’kacher, R. (2024). Telomere Dysfunction in Pediatric Patients with Differences/Disorders of Sexual Development. Biomedicines, 12(3), Article 565. https://doi.org/10.3390/biomedicines12030565
Skov, M., Ruijs, T. Q., Grønnebæk, T. S., Skals, M., Riisager, A., Winther, J. B., Dybdahl, K. L. T., Findsen, A., Morgen, J. J., Huus, N., Broch-Lips, M., Nielsen, O. B., de Cuba, C. M. K. E., Heuberger, J. A. A. C., de Kam, M. L., Tannemaat, M., Verschuuren, J. J. G. M., Knutsen, L. J. S., Kelly, N. M. ... Pedersen, T. H. (2024). The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis. Science Translational Medicine, 16(739). https://doi.org/10.1126/scitranslmed.adk9109