Peer-reviewed publications

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Bengtsen, M. B., Heide-Jørgensen, U., Borre, M., Knudsen, J. S. & Nørgaard, M. (2023). Acute urinary retention in men: 21-year trends in incidence, subsequent benign prostatic hyperplasia-related treatment and mortality: A Danish population-based cohort study. The Prostate, 83(1), 87-96. https://doi.org/10.1002/pros.24440

Nielsen, S. S. E., Holst, M. R., Langthaler, K., Bruun, E. H., Brodin, B. & Nielsen, M. S. (2023). Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells. Fluids and Barriers of the CNS, 20(1), 2. https://doi.org/10.1186/s12987-022-00404-1

Carrero, J. J., Fu, E. L., Vestergaard, S. V., Jensen, S. K., Gasparini, A., Mahalingasivam, V., Bell, S., Birn, H., Heide-Jørgensen, U., Clase, C. M., Cleary, F., Coresh, J., Dekker, F. W., Gansevoort, R. T., Hemmelgarn, B. R., Jager, K. J., Jafar, T. H., Kovesdy, C. P., Sood, M. M. ... Nitsch, D. (2023). Defining measures of kidney function in observational studies using routine health care data: methodological and reporting considerations. Kidney International, 103(1), 53-69. https://doi.org/10.1016/j.kint.2022.09.020

Rothemejer, F. H., Pi Lauritsen, N., Juhl, A. K., Schleimann, M. H., König, S., Søgaard, O. S., Bak, R. & Tolstrup, M. (2023). Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus. Viruses, 15(1). https://www.mdpi.com/1999-4915/15/1/202

Jensen, A. M. G., Kitago, Y., Fazeli, E., Vægter, C. B., Small, S. A., Petsko, G. A. & Andersen, O. M. (2023). Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer. Proceedings of the National Academy of Sciences of the United States of America, 120(4), e2212180120. https://doi.org/10.1073/pnas.2212180120

iPSYCH-Broad Consortium (2023). Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity. Scientific Reports, 13(1), 429. https://doi.org/10.1038/s41598-022-26845-0

Vad-Nielsen, J., Staunstrup, N. H., Lindkvist Kjeldsen, M., Dybdal, N., Flandin, G., Stradis, C. D., Daugaard, T. F., Larsen, T. V., Månsson, C. T., Doktor, T. K., Sørensen, B. S. & Nielsen, A. L. (2023). Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells. Translational lung cancer research, 12(1). https://doi.org/10.21037/tlcr-22-507

Nielsen, M. A., Køster, D., Greisen, S., Troldborg, A., Stengaard-Pedersen, K., Junker, P., Hørslev-Petersen, K., Hetland, M. L., Østergaard, M., Hvid, M., Leffler, H., Kragstrup, T. W. & Deleuran, B. (2023). Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis. Scandinavian Journal of Rheumatology, 52(1), 33-41. https://doi.org/10.1080/03009742.2021.1992860

Steffensen, E. H., Pedersen, L. H., Lou, S. & Vogel, I. (2023). Is the first-trimester combined screening result associated with the phenotype of Down syndrome? A population-based cohort study. Prenatal Diagnosis, 43(1), 51-61. https://doi.org/10.1002/pd.6284

Sahana, J., Cortés-Sánchez, J. L., Sandt, V., Melnik, D., Corydon, T. J., Schulz, H., Cai, Z., Evert, K., Grimm, D. & Wehland, M. (2023). Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells. International Journal of Molecular Sciences , 24(2). https://doi.org/10.3390/ijms24021181

Faraj, S. E., Valsecchi, W. M., Ferreira-Gomes, M., Centeno, M., Saint Martin, E. M. S., Fedosova, N., Rossi, J. P. F. C., Montes, M. & Rossi, R. C. (2023). Measurements of Na+-occluded intermediates during the catalytic cycle of the Na+/K+-ATPase provide novel insights into the mechanism of Na+ transport. Journal of Biological Chemistry. https://doi.org/10.1016/j.jbc.2022.102811

Lunding, M., Blauenfeldt, R., Just, J. & Drasbek, K. R. (2023). Remote Ischemic Conditioning induced miRNA responses in humans. Conditioning Medicine, 5(4), 112-122.

Toth, A. E., Klepe, A., Lipka, D. V., Goldeman, C., Brodin, B. & Nielsen, M. S. (2023). SorLA in astrocytes regulates blood-brain barrier integrity. Frontiers in Drug Delivery. https://doi.org/10.3389/fddev.2022.1082689

Zhou, J., Rasmussen, N. L., Olsvik, H. L., Akimov, V., Hu, Z., Evjen, G., Kaeser-Pebernard, S., Sankar, D. S., Roubaty, C., Verlhac, P., van de Beck, N., Reggiori, F., Abudu, Y. P., Blagoev, B., Lamark, T., Johansen, T. & Dengjel, J. (2023). TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. The Journal of Cell Biology, 222(2). https://doi.org/10.1083/jcb.202108144

Vierbuchen, T., Agarwal, S., Johnson, J. L., Galia, L., Lei, X., Stein, K., Olagnier, D., Gaede, K. I., Herzmann, C., Holm, C. K., Heine, H., Pai, A., O'Hara Hall, A., Hoebe, K. & Fitzgerald, K. A. (2023). The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proceedings of the National Academy of Sciences of the United States of America, 120(1), e2213715120. https://doi.org/10.1073/pnas.2213715120

Lamarche, B. A., Thomsen, J. S., Andreasen, C. M., Lievers, W. B. & Andersen, T. L. (2022). 2D size of trabecular bone structure units (BSU) correlate more strongly with 3D architectural parameters than age in human vertebrae. Bone, 160, [116399]. https://doi.org/10.1016/j.bone.2022.116399

Götberg, M., Berntorp, K., Rylance, R., Christiansen, E. H., Yndigegn, T., Gudmundsdottir, I. J., Koul, S., Sandhall, L., Danielewicz, M., Jakobsen, L., Olsson, S. E., Olsson, H., Omerovic, E., Calais, F., Lindroos, P., Maeng, M., Venetsanos, D., James, S. K., Kåregren, A. ... Fröbert, O. (2022). 5-Year Outcomes of PCI Guided by Measurement of Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve. Journal of the American College of Cardiology, 79(10), 965-974. https://doi.org/10.1016/j.jacc.2021.12.030

Lindahl, L. M., Iversen, L., Ødum, N. & Kilian, M. (2022). Staphylococcus aureus and Antibiotics in Cutaneous T-Cell Lymphoma. Dermatology, 238(3), 551-553. https://doi.org/10.1159/000517829

Jovic, D., Yu, Y., Wang, D., Wang, K., Li, H., Xu, F., Liu, C., Liu, J. & Luo, Y. (2022). A Brief Overview of Global Trends in MSC-Based Cell Therapy. Stem Cell Reviews and Reports, 18(5), 1525-1545. https://doi.org/10.1007/s12015-022-10369-1

Volkmann, A., Koopman, G., Mooij, P., Verschoor, E. J., Verstrepen, B. E., Bogers, W. M. J. M., Idorn, M., Paludan, S. R., Vang, S., Nielsen, M. A., Sander, A. F., Schmittwolf, C., Hochrein, H. & Chaplin, P. (2022). A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques. Frontiers in Immunology, 13, [857440]. https://doi.org/10.3389/fimmu.2022.857440

Grimm, E., van der Hoeven, F., Sardella, D., Willig, K. I., Engel, U., Veits, N., Engel, R., Cavalcanti-Adam, E. A., Bestvater, F., Bordoni, L., Jennemann, R., Schönig, K., Schiessl, I. M. & Sandhoff, R. (2022). A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis. PLOS ONE, 17(9), [e0273660]. https://doi.org/10.1371/journal.pone.0273660

Herold, J. & Kalucka, J. (2022). A Rapid Adaptable Method for Isolation of Endothelial Cells from Human Adipose Tissue. In A. V. Benest (Ed.), Angiogenesis (pp. 235-250). Humana Press. Methods in Molecular Biology Vol. 2441 https://doi.org/10.1007/978-1-0716-2059-5_18

de Rooij, L. P. M. H., Becker, L. M. & Carmeliet, P. (2022). A Role for the Vascular Endothelium in Post-Acute COVID-19? Circulation, 145(20), 1503-1505. https://doi.org/10.1161/CIRCULATIONAHA.122.059231

Demir, F. & Huesgen, P. F. (2022). A User Guide to Validation, Annotation, and Evaluation of N-Terminome Datasets with MANTI. In Methods in Molecular Biology (pp. 271-283). Humana Press Inc. Methods in Molecular Biology Vol. 2447 https://doi.org/10.1007/978-1-0716-2079-3_22

Wichmann, T. O., Damkier, H. H. & Pedersen, M. (2022). A brief overview of the cerebrospinal fluid system and its implications for brain and spinal cord diseases. Frontiers in Human Neuroscience, 15, [737217]. https://doi.org/10.3389/fnhum.2021.737217

Gammelgaard Trans, J., Krogstrup, N. V., Oltean, M., Jespersen, B., Bodilsen Nielsen, M. & Birn, H. (2022). A comparison of four established GFR formulas to estimate measured GFR and changes in GFR in adult kidney transplant recipients. Scandinavian Journal of Clinical & Laboratory Investigation, 82(4), 296-303. https://doi.org/10.1080/00365513.2022.2084697

Sun, B., Ni, M., Tian, S., Guo, W., Cai, S., Sondergaard, M. T., Chen, Y., Mu, Y., Estillore, J. P., Wang, R., Chen, J., Overgaard, M. T., Fill, M., Ramos-Franco, J., Nyegaard, M. & Wayne Chen, S. R. (2022). A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice. Journal of Cellular Physiology, 237(8), 3305-3316. https://doi.org/10.1002/jcp.30783

Andersen, O. M., Bøgh, N., Landau, A. M., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P., Nyengaard, J. R., Jacobsen, K. R., Jørgensen, M. M., Holm, I. E., Kristensen, M. L., Alstrup, A. K. O., Hansen, E. S. S., Teunissen, C. E., Breidenbach, L., Droescher, M., Liu, Y., Pedersen, H. S. ... Sørensen, C. B. (2022). A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency. Cell Reports Medicine, 3(9), [100740]. https://doi.org/10.1016/j.xcrm.2022.100740

Ipsen, M. B., Sørensen, E. M. G., Thomsen, E. A., Weiss, S., Haldrup, J., Dalby, A., Palmfeldt, J., Bross, P., Rasmussen, M., Fredsøe, J., Klingenberg, S., Jochumsen, M. R., Bouchelouche, K., Ulhøi, B. P., Borre, M., Mikkelsen, J. G. & Sørensen, K. D. (2022). A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer. Oncogene, 41(37), 4271-4281. https://doi.org/10.1038/s41388-022-02427-2

Andreakos, E., Abel, L., Vinh, D. C., Kaja, E., Drolet, B. A., Zhang, Q., O’Farrelly, C., Novelli, G., Rodríguez-Gallego, C., Haerynck, F., Prando, C., Pujol, A., Casanova, J. L. & COVID Human Genetic Effort (2022). A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection. Nature Immunology, 23(2), 159-164. https://doi.org/10.1038/s41590-021-01030-z

Bernth Jensen, J. M., Hansen, A. T., Söderström, A., Jørgensen, C. S., Larsen, C. S., Skov Sørensen, U. B., Thiel, S. & Petersen, M. S. (2022). A low level of naturally occurring antibodies associates with functional antibody deficiency. Clinical Immunology, 241, [109070]. https://doi.org/10.1016/j.clim.2022.109070

Vilsen, B., Holm, R. & Nielsen, H. N. (2022). A novel super-efficient rescue mutation restoring the functional capability of Na,K-ATPase α3 in neurological disease. 58-59. Poster session presented at 16th International Conference on NA,K-ATPase and Related Transport ATPases, Banff, Canada.

Holm, R., Nielsen, H. N. & Vilsen, B. (2022). A novel super-efficient rescue mutation restoring the functional capability of Na,K-ATPase α3 in neurological disease.. Abstract from 16th International Conference on NA,K-ATPase and Related Transport ATPases, Banff, Canada.

Pirhaghi, M., Frank, S. A., Alam, P., Nielsen, J., Sereikaite, V., Gupta, A., Strømgaard, K., Andreasen, M., Sharma, D., Saboury, A. A. & Otzen, D. E. (2022). A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. Journal of Biological Chemistry, 298(12), [102688]. https://doi.org/10.1016/j.jbc.2022.102688

Antaki, D., Guevara, J., Maihofer, A. X., Klein, M., Gujral, M., Grove, J., Carey, C. E., Hong, O., Arranz, M. J., Hervas, A., Corsello, C., Vaux, K. K., Muotri, A. R., Iakoucheva, L. M., Courchesne, E., Pierce, K., Gleeson, J. G., Robinson, E. B., Nievergelt, C. M. & Sebat, J. (2022). A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nature Genetics, 54(9), 1284-1292. https://doi.org/10.1038/s41588-022-01064-5

Brent, M. B. (2022). A review of the skeletal effects of exposure to high altitude and potential mechanisms for hypobaric hypoxia-induced bone loss. Bone, 154, [116258]. https://doi.org/10.1016/j.bone.2021.116258

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H. ... Understanding Society Scientific Group (2022). A saturated map of common genetic variants associated with human height. Nature, 610(7933), 704–712. https://doi.org/10.1038/s41586-022-05275-y

Yde, J., Wu, Q., Borg, J. F., Fenton, R. A. & Moeller, H. B. (2022). A systems-level analysis of bile acids effects on rat colon epithelial cells. American Journal of Physiology - Gastrointestinal and Liver Physiology, 322(1), G34-G48. https://doi.org/10.1152/ajpgi.00178.2021

Gao, Z., Ravendran, S., Mikkelsen, N. S., Haldrup, J., Cai, H., Ding, X., Paludan, S. R., Thomsen, M. K., Mikkelsen, J. G. & Bak, R. O. (2022). A truncated reverse transcriptase enhances prime editing by split AAV vectors. Molecular Therapy, 30(9), 2942-2951. https://doi.org/10.1016/j.ymthe.2022.07.001

Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O'Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A. ... Kazak, L. (2022). ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism, 4(11), 1459-1473. https://doi.org/10.1038/s42255-022-00667-w

Ernst, C., Aalkjær, C. & Bek, T. (2022). ATP induced calcium signaling activity in perivascular cells differ at different vascular branch levels in the porcine retina. Microvascular Research, 139, [104256]. https://doi.org/10.1016/j.mvr.2021.104256

Agrawal, A., Ellegaard, M., Haanes, K. A., Wang, N., Gartland, A., Ding, M., Praetorius, H. & Jørgensen, N. R. (2022). Absence of P2Y₂ Receptor Does Not Prevent Bone Destruction in a Murine Model of Muscle Paralysis-Induced Bone Loss. Frontiers in Endocrinology, 13, [850525]. https://doi.org/10.3389/fendo.2022.850525

Rinschen, M. M., Palygin, O., El-Meanawy, A., Domingo-Almenara, X., Palermo, A., Dissanayake, L. V., Golosova, D., Schafroth, M. A., Guijas, C., Demir, F., Jaegers, J., Gliozzi, M. L., Xue, J., Hoehne, M., Benzing, T., Kok, B. P., Saez, E., Bleich, M., Himmerkus, N. ... Staruschenko, A. (2022). Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension. Nature Communications, 13(1), [4099]. https://doi.org/10.1038/s41467-022-31670-0

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J. ... Vilhjálmsson, B. J. (2022). Accounting for age of onset and family history improves power in genome-wide association studies. American Journal of Human Genetics, 109(3), 417-432. https://doi.org/10.1016/j.ajhg.2022.01.009

Ring, T., Rees, S. E. & Frische, S. (2022). Acid content and buffer-capacity: a charge-balance perspective. Scandinavian Journal of Clinical and Laboratory Investigation, 82(5), 356-362. https://doi.org/10.1080/00365513.2022.2092903

Imenez Silva, P. H., Unwin, R., Hoorn, E. J., Ortiz, A., Trepiccione, F., Nielsen, R., Pesic, V., Hafez, G., Fouque, D., Massy, Z. A., De Zeeuw, C. I., Capasso, G., Wagner, C. A. & CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) (2022). Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease. Nephrology Dialysis Transplantation, 37(Supplement 2), ii4-ii12. https://doi.org/10.1093/ndt/gfab216

Wu, A., Wolley, M. J., Wu, Q., Cowley, D., Palmfeldt, J., Welling, P. A., Fenton, R. A. & Stowasser, M. (2022). Acute Intravenous NaCl and Volume Expansion Reduces Sodium-Chloride Cotransporter Abundance and Phosphorylation in Urinary Extracellular Vesicles. Kidney360, 3(5), 910-921. https://doi.org/10.34067/KID.0000362022

Andersen, C. U., Nielsen, L. P., Møller, J. M. & Olesen, A. E. (2022). Acute drug poisonings leading to hospitalization. Basic and Clinical Pharmacology and Toxicology, 130(2), 328-336. https://doi.org/10.1111/bcpt.13688

Ernstsen, C. V., Login, F. H., Schelde, A-S. B., Therkildsen, J. R., Møller-Jensen, J., Nørregaard, R., Prætorius Øhrwald, H. & Nejsum, L. N. (2022). Acute pyelonephritis: increased plasma membrane targeting of renal aquaporin-2. Acta Physiologica, 234(2), [e13760]. https://doi.org/10.1111/apha.13760

AlZaim, I., Eid, A. H., Abd-Elrahman, K. S. & El-Yazbi, A. F. (2022). Adipose tissue mitochondrial dysfunction and cardiometabolic diseases: On the search for novel molecular targets. Biochemical Pharmacology, 206, [115337]. https://doi.org/10.1016/j.bcp.2022.115337

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