Smith, C. P., Lee, W.-K., Haley, M.
, Poulsen, S. B., Thévenod, F.
& Fenton, R. A. (2019).
Proximal tubule transferrin uptake is modulated by cellular iron and mediated by apical membrane megalin-cubilin complex and transferrin receptor 1.
Journal of Biological Chemistry,
294(17), 7025-7036.
https://doi.org/10.1074/jbc.RA118.006390
Trzaskowski, M., Mehta, D., Peyrot, W. J., Hawkes, D., Davies, D., Howard, D. M., Kemper, K. E., Sidorenko, J., Maier, R., Ripke, S.
, Mattheisen, M., Baune, B. T., Grabe, H. J., Heath, A. C., Jones, L., Jones, I., Madden, P. A. F., McIntosh, A. M., Breen, G. ... Major Depress Disorder Working G (2019).
Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
180(6), 439-447.
https://doi.org/10.1002/ajmg.b.32713
Lipachev, N., Arnst, N., Melnikova, A., Jaalinoja, H., Kochneva, A., Zhigalov, A., Kulesskaya, N., Aganov, A., Mavlikeev, M., Rauvala, H., Kiyasov, A. P.
& Paveliev, M. (2019).
Quantitative changes in perineuronal nets in development and posttraumatic condition.
Journal of Molecular Histology,
50(3), 203-216.
https://doi.org/10.1007/s10735-019-09818-y
Toussaint, L., Indelicato, D. J., Stokkevåg, C. H.
, Lassen, Y. A., Pedro, C.
, Mikkelsen, R., Di Pinto, M., Li, Z., Flampouri, S.
, Vestergaard, A., Petersen, J. B. B., Schrøder, H., Høyer, M. & Muren, L. P. (2019).
Radiation doses to brain substructures associated with cognition in radiotherapy of pediatric brain tumors.
Acta Oncologica,
58(10), 1457-1462.
https://doi.org/10.1080/0284186X.2019.1629014
Cheng, L., Poulsen, S. B., Wu, Q., Esteva-Font, C., Olesen, E. T. B., Peng, L., Olde, B., Leeb-Lundberg, L. M. F.
, Pisitkun, T., Rieg, T.
, Dimke, H. & Fenton, R. A. (2019).
Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter.
Journal of the American Society of Nephrology : JASN,
30(8), 1454-1470.
https://doi.org/10.1681/ASN.2018101025
Søndergaard, A. M., Overgaard, C. B., Mazur, A., Postnov, D. D.
, Matchkov, V. V. & Aalkjaer, C. (2019).
Rat mesenteric small artery neurogenic dilatation is predominantly mediated by β1 -adrenoceptors in vivo.
The Journal of Physiology,
597(7), 1819-1831.
https://doi.org/10.1113/JP277368
Nassef, M. Z.
, Kopp, S., Wehland, M., Melnik, D., Sahana, J., Krüger, M.
, Corydon, T. J., Oltmann, H., Schmitz, B., Schütte, A., Bauer, T. J., Infanger, M.
& Grimm, D. (2019).
Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells.
International Journal of Molecular Sciences ,
20(13), Article 3156.
https://doi.org/10.3390/ijms20133156
Olsen, D., Kaas, M., Lundhede, J., Molgaard, S., Nykjær, A., Kjolby, M., Østergaard, S. D. & Glerup, S. (2019).
Reduced Alcohol Seeking and Withdrawal Symptoms in Mice Lacking the BDNF Receptor SorCS2.
Frontiers in Pharmacology,
10(MAY), Article 499.
https://doi.org/10.3389/fphar.2019.00499
Bilde, K., Olesen, R. H., Ernst, EH., Mamsen, L. S.
, Amoushahi, M., Lykke-Hartmann, K., Ernst, E. & Larsen, A. (2019).
Reduced hepatic metallothionein expression in first trimester fetuses in response to intrauterine smoking exposure – a consequence of low maternal zinc levels? Human Reproduction,
34(11), 2129-2143.
https://doi.org/10.1093/humrep/dez197
Larsen, J. B., Laursen, M. A., Hvas, C. L., Larsen, K. M., Thiel, S. & Hvas, A. M. (2019).
Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock.
Thrombosis and Haemostasis,
119(6), 952-961.
https://doi.org/10.1055/s-0039-1685140
Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T.
, Børglum, A., Mors, O., Nordentoft, M.
, Mortensen, P. B. & Hougaard, D. M. (2019).
Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders.
Translational Psychiatry,
9(1), Article 252.
https://doi.org/10.1038/s41398-019-0587-2
Ribeiro, D. E., Casarotto, P., Stanquini, L., Pinto e Silva, M. A.
, Biojone, C., Wegener, G. & Joca, S. (2019).
Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model.
PeerJ.
Christensen, L. F. B., Jensen, K. F., Nielsen, J., Vad, B. S., Christiansen, G. & Otzen, D. E. (2019).
Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation.
ACS Omega,
4(2), 4029-4039.
https://doi.org/10.1021/acsomega.8b03590
Hsiao, J. H. T., Purushothuman, S.
, Jensen, P. H., Halliday, G. M. & Kim, W. S. (2019).
Reductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain.
Frontiers in Neuroscience,
13, Article 1187.
https://doi.org/10.3389/fnins.2019.01187
Høgild, M. L., Gudiksen, A., Pilegaard, H.
, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N. (2019).
Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men.
Physiological Reports,
7(21), Article e14285.
https://doi.org/10.14814/phy2.14285
Nielsen, M. B., Krogstrup, N. V., Oltean, M., Nieuwenhuijs-Moeke, G. J., Dor, F. J. M. F.
, Birn, H. & Jespersen, B. (2019).
Remote ischaemic conditioning and early changes in plasma creatinine as markers of one year kidney graft function-A follow-up of the CONTEXT study.
PLOS ONE,
14(12), Article e0226882.
https://doi.org/10.1371/journal.pone.0226882
Raikwar, N., Braverman, C., Snyder, P. M.
, Fenton, R. A., Meyerholz, D. K., Abboud, F. M. & Harwani, S. C. (2019).
Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention.
American Journal of Physiology: Heart and Circulatory Physiology,
317(3), H517-H530.
https://doi.org/10.1152/ajpheart.00234.2019
Damsgaard, C., Lauridsen, H., Funder, A. M. D., Thomsen, J. S., Desvignes, T., Crossley, II, D. A., Møller, P. R., Huong, D. T. T., Phuong, N. T., Detrich, H. W.
, Brüel, A., Wilkens, H., Warrant, E.
, Wang, T., Nyengaard, J. R., Berenbrink, M.
& Bayley, M. (2019).
Retinal oxygen supply shaped the functional evolution of the vertebrate eye.
eLife,
8, Article e52153.
https://doi.org/10.7554/eLife.52153
Njølstad, P. R., Andreassen, O. A., Brunak, S.
, Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A.
, Mortensen, P. B. ... Stefánsson, K. (2019).
Roadmap for a precision-medicine initiative in the Nordic region.
Nature Genetics,
51(6), 924-930.
https://doi.org/10.1038/s41588-019-0391-1
Gasse, C., Wimberley, T., Wang, Y.
, Mors, O., Børglum, A., Als, T. D., Werge, T., Nordentoft, M., Hougaard, D. M.
& Horsdal, H. T. (2019).
Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia.
Schizophrenia Research,
212, 79-85.
https://doi.org/10.1016/j.schres.2019.08.008
Storm, T., Burgoyne, T., Dunaief, J. L.
, Christensen, E. I., Futter, C.
& Nielsen, R. (2019).
Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.
Investigative Ophthalmology & Visual Science,
60(1), 322-330.
https://doi.org/10.1167/iovs.18-25667
Bach, A., Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, H., Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N.
, Lykke-Hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, K. (2019).
Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor.
Neuropharmacology,
150, 100-111.
https://doi.org/10.1016/j.neuropharm.2019.02.035
George, A. F., Jang, K. S.
, Nyegaard, M., Neidleman, J., Spitzer, T., Xie, G., Chen, J., Herzig, E., Greene, W. C., Giudice, L. C. & Roan, N. R. (2019).
Seminal plasma promotes decidualization of endometrial stromal fibroblasts and induces a potent transcriptional response involving IL-11 induction. Abstract from Society for the Study of Reproduction annual meeting in San Jose , San Jose, California, United States.
Nassef, M. Z.
, Kopp, S., Melnik, D., Corydon, T. J., Sahana, J., Krüger, M.
, Wehland, M., Bauer, T. J., Liemersdorf, C., Hemmersbach, R., Infanger, M.
& Grimm, D. (2019).
Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells.
International Journal of Molecular Sciences ,
20(22), Article 5730.
https://doi.org/10.3390/ijms20225730
Leng, L., Sun, J.
, Huang, J., Gong, F., Yang, L., Zhang, S., Yuan, X.
, Fang, F., Xu, X.
, Luo, Y., Bolund, L., Peters, B. A., Lu, G., Jiang, T., Xu, F. & Lin, G. (2019).
Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development.
Cell Stem Cell,
25(5), 697-712.e6.
https://doi.org/10.1016/j.stem.2019.09.004
Muscolini, M., Castiello, L., Palermo, E., Zevini, A., Ferrari, M.
, Olagnier, D. & Hiscott, J. (2019).
SIRT1 modulates the sensitivity of prostate cancer cells to vesicular stomatitis virus oncolysis.
Journal of Virology,
93, Article e00626-19.
https://doi.org/10.1128/JVI.00626-19
Sieljacks, P., Wang, J., Grønnebæk, T. S., Rindom, E., Jakobsgaard, J. E., Herskind, J. H., Gravholt, A.
, Møller, A. B., Musci, R.
, de Paoli, F. V., Hamilton, K. L., Miller, B. F.
& Vissing, K. (2019).
Six Weeks of Low-Load Blood Flow Restricted and High-Load Resistance Exercise Training Produce Similar Increases in Cumulative Myofibrillar Protein Synthesis and Ribosomal Biogenesis in Healthy Males.
Frontiers in Physiology,
10(MAY), Article 649.
https://doi.org/10.3389/fphys.2019.00649
Paetzold, B., Willis, J. R., Pereira de Lima, J., Knödlseder, N.
, Brüggemann, H., Quist, S. R., Gabaldón, T. & Güell, M. (2019).
Skin microbiome modulation induced by probiotic solutions.
Microbiome,
7(1), Article 95.
https://doi.org/10.1186/s40168-019-0709-3
Staehr, C., Hangaard, L., Bouzinova, E. V., Kim, S., Rajanathan, R., Boegh Jessen, P., Luque, N., Xie, Z.
, Lykke-Hartmann, K., Sandow, S. L.
, Aalkjær, C. & Matchkov, V. V. (2019).
Smooth muscle Ca2+ sensitization causes hypercontractility of middle cerebral arteries in mice bearing the familial hemiplegic migraine type 2 associated mutation.
Journal of Cerebral Blood Flow and Metabolism,
39(8), 1570-1587. Article 0271678X18761712.
https://doi.org/10.1177/0271678X18761712
Warrier, V., Toro, R., Won, H., Leblond, C. S., Cliquet, F., Delorme, R., De Witte, W., Bralten, J., Chakrabarti, B.
, Børglum, A. D., Grove, J., Poelmans, G., Hinds, D. A., Bourgeron, T.
& Baron-Cohen, S. (2019).
Social and non-social autism symptoms and trait domains are genetically dissociable.
Communications Biology,
2(1), Article 328.
https://doi.org/10.1038/s42003-019-0558-4
Malik, A. R., Szydlowska, K., Nizinska, K., Asaro, A., van Vliet, E. A., Popp, O., Dittmar, G., Fritsche-Guenther, R., Kirwan, J. A.
, Nykjaer, A., Lukasiuk, K., Aronica, E. & Willnow, T. E. (2019).
SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.
Cell Reports,
26(10), 2792-2804.e6.
https://doi.org/10.1016/j.celrep.2019.02.027
Pietilä, M., Sahgal, P., Peuhu, E., Jäntti, N. Z., Paatero, I., Närvä, E., Al-Akhrass, H., Lilja, J., Georgiadou, M.
, Andersen, O. M., Padzik, A., Sihto, H., Joensuu, H., Blomqvist, M., Saarinen, I., Boström, P. J., Taimen, P. & Ivaska, J. (2019).
SORLA regulates endosomal trafficking and oncogenic fitness of HER2.
Nature Communications,
10(1), 1-16. Article 2340.
https://doi.org/10.1038/s41467-019-10275-0
Richner, M., Pallesen, L. T., Ulrichsen, M., Poulsen, E. T., Holm, T. H., Login, H., Castonguay, A., Lorenzo, L.-E.
, Gonçalves, N. P., Andersen, O. M., Lykke-Hartmann, K., Enghild, J. J., Rønn, L. C. B., Malik, I. J., De Koninck, Y., Bjerrum, O. J.
, Vægter, C. B. & Nykjær, A. (2019).
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.
Science Advances,
5(6), Article eaav9946.
https://doi.org/10.1126/sciadv.aav9946
Etzerodt, A., Tsalkitzi, K.
, Maniecki, M., Damsky, W., Delfini, M., Baudoin, E., Moulin, M., Bosenberg, M.
, Graversen, J. H., Auphan-Anezin, N.
, Moestrup, S. K. & Lawrence, T. (2019).
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of Experimental Medicine,
216(10), 2394-2411.
https://doi.org/10.1084/jem.20182124
Ruesink, H., Reimer, L., Gregersen, E., Moeller, A., Betzer, C. & Jensen, P. H. (2019).
Stabilization of α-synuclein oligomers using formaldehyde.
PLOS ONE,
14(10), Article e0216764.
https://doi.org/10.1371/journal.pone.0216764
Bruggemann, H., Poehlein, A., Brzuszkiewicz, E.
, Scavenius, C., Enghild, J. J., Al-Zeer, M. A., Brinkmann, V.
, Jensen, A. & Soderquist, B. (2019).
Staphylococcus saccharolyticus Isolated From Blood Cultures and Prosthetic Joint Infections Exhibits Excessive Genome Decay.
Frontiers in Microbiology,
10, Article 478.
https://doi.org/10.3389/fmicb.2019.00478
Andersen, M. N., Etzerodt, A., Graversen, J. H., Holthof, L. C.
, Moestrup, S. K., Hokland, M. & Møller, H. J. (2019).
STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes.
Cancer Immunology, Immunotherapy,
68(3), 489-502.
https://doi.org/10.1007/s00262-019-02301-3
Hansen, A. L., Mukai, K., Schopfer, F. J., Taguchi, T.
& Holm, C. K. (2019).
STING palmitoylation as a therapeutic target.
Cellular & molecular immunology,
16(3), 236-241.
https://doi.org/10.1038/s41423-019-0205-5
Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Joram, N.
, Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C.
, Petersen, S. V., Lindorff-Larsen, K.
, Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V.
& Andersen, G. R. (2019).
Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Frontiers in Immunology,
10, Article 2007.
https://doi.org/10.3389/fimmu.2019.02007
Sitsel, A., De Raeymaecker, J.
, Drachmann, N. D., Derua, R., Smaardijk, S.
, Andersen, J. L., Vandecaetsbeek, I., Chen, J., De Maeyer, M., Waelkens, E.
, Olesen, C., Vangheluwe, P.
& Nissen, P. (2019).
Structures of the heart specific SERCA2a Ca
2+
-ATPase.
EMBO Journal,
38(5), Article e100020.
https://doi.org/10.15252/embj.2018100020