Vakulskas, C. A., Dever, D. P., Rettig, G. R., Turk, R., Jacobi, A. M., Collingwood, M. A., Bode, N. M., McNeill, M. S., Yan, S., Camarena, J., Lee, C. M., Park, S. H., Wiebking, V.
, Bak, R. O., Gomez-Ospina, N., Pavel-Dinu, M., Sun, W., Bao, G., Porteus, M. H. & Behlke, M. A. (2018).
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
Nature Medicine,
24(8), 1216-1224.
https://doi.org/10.1038/s41591-018-0137-0
Hinrichs, G. R., Michelsen, J. S., Zachar, R., Friis, U. G., Svenningsen, P.
, Birn, H., Bistrup, C. & Jensen, B. L. (2018).
Albuminuria in kidney transplant recipients is associated with increased urinary serine proteases and activation of the epithelial sodium channel.
American Journal of Physiology: Renal Physiology,
315(1), F151-F160.
https://doi.org/10.1152/ajprenal.00545.2017
Wang, H., Stewart, T., Toledo, J. B., Ginghina, C., Tang, L., Atik, A., Aro, P., Shaw, L. M., Trojanowski, J. Q., Galasko, D. R., Edland, S.
, Jensen, P. H., Shi, M., Zhang, J. & Alzheimer’s Disease Neuroimaging Initiative (2018).
A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment.
Journal of Alzheimer's Disease,
61(4), 1541-1553.
https://doi.org/10.3233/JAD-171013
Betzer, C., Lassen, L. B., Olsen, A., Kofoed, R. H., Reimer, L., Gregersen, E., Zheng, J., Calì, T., Gai, W.-P., Chen, T.
, Moeller, A., Brini, M., Fu, Y., Halliday, G.
, Brudek, T., Aznar, S., Pakkenberg, B.
, Andersen, J. P. & Jensen, P. H. (2018).
Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
EMBO Reports,
19(5), Article e44617.
https://doi.org/10.15252/embr.201744617
Wang, H., Dutta, S., Kelly, R. S.
, Rudra, A., Li, S., Zhang, Q. Q., Zhang, Q. Q., Wu, Y. X., Cao, M. Z., Wang, B.
, Li, J. G. & Zhang, H. C. (2018).
Amber fossils reveal the Early Cenozoic dipterocarp rainforest in central Tibet.
Palaeoworld,
27(4), 506-513.
https://doi.org/10.1016/j.palwor.2018.09.006
Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018).
A modified monomeric red fluorescent protein reporter for assessing CRISPR activity.
Frontiers in Cell and Developmental Biology,
6(MAY), Article 54.
https://doi.org/10.3389/fcell.2018.00054
Blechingberg, J., Poulsen, A. S. A., Kjølby, M., Monti, G., Allen, M.
, Ivarsen, A. K., Lincoln, S. J., Thotakura, G.
, Vægter, C. B., Ertekin-Taner, N.
, Nykjær, A. & Andersen, O. M. (2018).
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
Neurobiology of Aging,
71, 266.e11-266.e24.
https://doi.org/10.1016/j.neurobiolaging.2018.06.021
Abu-Lubad, M., Alzoubi, H., Jarajreh, D., Sawalqa, A. A.
, Bruggemann, H., Albataineh, E., Aqel, A. & Al-Zeer, M. (2018).
Analysis of Genotypes Amongst Jordanians' Dental Plaque Samples.
Today in Medicine. Gastroenterology,
11(1), 46-51.
https://doi.org/10.14740/gr947w
Reinbold, C. S., Forstner, A. J., Hecker, J., Fullerton, J. M., Hoffmann, P., Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A. ... Cichon, S. (2018).
Analysis of the influence of microRNAs in lithium response in bipolar disorder.
Frontiers in Psychiatry,
9(MAY), Article 207.
https://doi.org/10.3389/fpsyt.2018.00207
Fullard, J. F.
, Hauberg, M. E., Bendl, J., Egervari, G., Cirnaru, M. D., Reach, S. M., Motl, J., Ehrlich, M. E., Hurd, Y. L. & Roussos, P. (2018).
An atlas of chromatin accessibility in the adult human brain.
Genome Research,
28(8), 1243-1252.
https://doi.org/10.1101/gr.232488.117
Yiallouris, A., Patrikios, I., Johnson, E. O., Sereti, E., Dimas, K., De Ford, C.
, Fedosova, N., Graier, W. F., Sokratous, K., Kyriakou, K. & Stephanou, A. (2018).
Annonacin promotes selective cancer cell death via NKA-dependent and SERCA dependent pathways.
Cell Death & Disease,
9(7), Article 764.
https://doi.org/10.1038/s41419-018-0772-x
Li, Y., Lapina, N., Weinzierl, N., Bonde, L.
, Boedtkjer, E., Schubert, R., Moshage, H., Wohlfahrt, P. & Schilling, L. (2018).
A novel method to isolate retinal and brain microvessels from individual rats: microscopic and molecular biological characterization and application in hyperglycemic animals.
Vascular Pharmacology,
110, 24-30.
Kvistgaard, H., Christensen, J. H., Johansson, J.-O.
, Gregersen, N., Siggaard Rittig, C., Rittig, S. & Corydon, T. J. (2018).
A Novel Synonymous Variant in the AVP Gene Associated with Autosomal Dominant Familial Neurohypophyseal Diabetes Insipidus Causes Partial RNA Missplicing.
Neuroendocrinology,
107(2), 167-180.
https://doi.org/10.1159/000491579
Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S.
, Nielsen, M. S., Moos, T. & Andresen, T. L. (2018).
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.
Theranostics,
8(12), 3416-3436.
https://doi.org/10.7150/thno.25228
Kühn, B., Brat, C., Fettel, J., Hellmuth, N., Maucher, I. V., Bulut, U., Hock, K. J., Grimmer, J., Manolikakes, G., Rühl, M., Kühn, A., Zacharowski, K.
, Matrone, C., Urbschat, A., Roos, J., Steinhilber, D.
& Maier, T. J. (2018).
Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells.
Biochemical Pharmacology,
155, 48-60.
https://doi.org/10.1016/j.bcp.2018.06.014
Jacobsen, K. M., Villadsen, N. L., Tørring, T., Nielsen, C. B., Salomón, T., Nielsen, M. M., Tsakos, M., Sibbersen, C., Scavenius, C., Nielsen, R., Christensen, E. I., Guerra, P. F., Bross, P., Pedersen, J. S., Enghild, J. J., Johannsen, M., Frøkiær, J., Overgaard, J., Horsman, M. R. ... Poulsen, T. B. (2018).
APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells.
Cell Chemical Biology,
25(11), 1337-1349.e12.
https://doi.org/10.1016/j.chembiol.2018.07.010
Gold, J., Marta, M., Meier, U. C.
, Christensen, T., Miller, D., Altmann, D., Holden, D., Bianchi, L., Adiutori, R., MacManus, D., Yousry, T., Schmierer, K., Turner, B. & Giovannoni, G. (2018).
A phase II baseline versus treatment study to determine the efficacy of raltegravir (Isentress) in preventing progression of relapsing remitting multiple sclerosis as determined by gadolinium-enhanced MRI: The INSPIRE study.
Multiple Sclerosis and Related Disorders,
24, 123-128.
https://doi.org/10.1016/j.msard.2018.06.002
Shim, J., Poulsen, C. B., Hagensen, M., Larsen, T., Heegaard, P. M. H., Christoffersen, C.
, Bolund, L., Schmidt, M.
, Liu, Y., Li, J.
, Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B. (2018).
Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis in Yucatan minipigs.
Transgenic Research,
27, 484.
https://doi.org/10.1007/s11248-018-0086-x
Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2018).
A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
Journal of Biological Chemistry,
293(17), 6269-6281.
https://doi.org/10.1074/jbc.RA117.001179
de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) (2018).
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Communications Biology,
1(1), Article 163.
https://doi.org/10.1038/s42003-018-0155-y
Dollerup, O. L., Christensen, B., Svart, M., Schmidt, M. S., Sulek, K.
, Ringgaard, S., Stødkilde-Jørgensen, H., Møller, N., Brenner, C., Treebak, J. T.
& Jessen, N. (2018).
A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects.
The American Journal of Clinical Nutrition,
108(2), 343-353.
https://doi.org/10.1093/ajcn/nqy132
Gravholt, C. H., Dollerup, O. L., Duval, L., Mejlgaard, E., Stribolt, K., Vang, S., Laursen, B. E., Knudsen, M., Thorsen, K., Hersmus, R., Looijenga, L. H. J.
& Stochholm, K. (2018).
A Rare Case of Embryonal Carcinoma in a Patient with Turner Syndrome without Y Chromosomal Material but Mutations in KIT, AKT1, and ZNF358 Demonstrated Using Exome Sequencing.
Sexual Development,
11(5-6), 262-268.
https://doi.org/10.1159/000484398
Buus, N. H., Carlsen, R. K., Khatir, D. S., Eiskjær, H., Mulvany, M. J. & Skov, K. (2018).
Arterial stiffness and peripheral vascular resistance in offspring of hypertensive parents: influence of sex and other confounders.
Journal of Hypertension,
36(4), 815–823.
https://doi.org/10.1097/HJH.0000000000001645
Kristensen, S. G., Liu, Q., Mamsen, L. S., Greve, T., Pors, S. E., Bjørn, A. B.
, Ernst, E., Macklon, K. T. & Andersen, C. Y. (2018).
A simple method to quantify follicle survival in cryopreserved human ovarian tissue.
Human reproduction (Oxford, England),
33(12), 2276-2284.
https://doi.org/10.1093/humrep/dey318
Yatime, L., Merle, N. S.
, Hansen, A. G., Friis, N. A., Østergaard, J. A., Bjerre, M., Roumenina, L. T.
, Thiel, S., Kristensen, P. & Andersen, G. R. (2018).
A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein.
Frontiers in Immunology,
9, Article 2822.
https://doi.org/10.3389/fimmu.2018.02822
Lodberg, A., Eijken, M., van der Eerden, B. C. J.
, Okkels, M. W., Thomsen, J. S. & Brüel, A. (2018).
A soluble activin type IIA receptor mitigates the loss of femoral neck bone strength and cancellous bone mass in a mouse model of disuse osteopenia.
Bone,
110, 326-334.
https://doi.org/10.1016/j.bone.2018.02.026
Hansen, M. B., Rasmussen, L. S., Garred, P., Pilely, K., Wahl, A. M., Perner, A.
, Madsen, M. B., Hedegaard, E. R., Simonsen, U. & Hyldegaard, O. (2018).
Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine with Morbidity and Mortality in Patients with Necrotizing Soft Tissue Infections.
Shock,
49(6), 667-674.
https://doi.org/10.1097/SHK.0000000000000975
Fotso Soh, J., Torres-Platas, S. G., Beaulieu, S., Mantere, O., Platt, R., Mucsi, I., Saury, S., Renaud, S., Levinson, A., Andreazza, A. C., Mulsant, B. H., Müller, D., Schaffer, A., Dols, A., Cervantes, P., Low, N. C., Herrmann, N.
, Christensen, B. M., Trepiccione, F. ... Rej, S. (2018).
Atorvastatin in the treatment of Lithium-induced nephrogenic diabetes insipidus: the protocol of a randomized controlled trial.
BMC Psychiatry,
18(1), Article 227.
https://doi.org/10.1186/s12888-018-1793-9
Prabakaran, T., Bodda, C., Krapp, C., Zhang, B.-C., Christensen, M. H., Sun, C., Reinert, L., Cai, Y., Jensen, S. B., Skouboe, M. K., Nyengaard, J. R., Thompson, C. B., Lebbink, R. J., Sen, G. C., van Loo, G.
, Nielsen, R., Komatsu, M.
, Nejsum, L. N., Jakobsen, M. R. ... Paludan, S. R. (2018).
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.
E M B O Journal,
37(8), Article E97858.
https://doi.org/10.15252/embj.201797858
Rosenbaek, L. L., Rizzo, F.
, Wu, Q., Rojas-Vega, L., Gamba, G., MacAulay, N., Staub, O.
& Fenton, R. A. (2018).
Author Correction: The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.
Scientific Reports,
8(1), 4215. Article 4215.
https://doi.org/10.1038/s41598-018-22153-8
Deretic, V., Prossnitz, E., Burge, M., Campen, M. J., Cannon, J., Liu, K. J., Sklar, L. A., Allers, L., Garcia, S. A., Baehrecke, E. H., Behrends, C., Cecconi, F., Codogno, P., Chen, G.-C., Elazar, Z., Eskelinen, E.-L., Fourie, B., Gozuacik, D., Hong, W. ... Klionsky, D. J. (2018).
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.
Autophagy,
14(6), 925-929.
https://doi.org/10.1080/15548627.2018.1465784
Løkke, A., Nielsen, L. P., Moberg, M., Marså, K., Titlestad, I. L., Kofod, L. M. & Godtfredsen, N. S. (2018).
Behandling af stabil kronisk obstruktiv lungesygdom.
Ugeskrift for Læger,
180(25).
http://ugeskriftet.dk/files/scientific_article_files/2018-06/V11170855_0.pdf
Olesen, M. T. J., Winther, A., Fejerskov, B., Dagnæs-Hansen, F., Simonsen, U. & Zelikin, A. N. (2018).
Bi‐Enzymatic Embolization Beads for Two‐Armed Enzyme‐Prodrug Therapy.
Advanced Therapeutics,
1(4), Article 1800023.
https://doi.org/10.1002/adtp.201800023
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, J.
, Glerup, S. & Nielsen, M. S. (2018).
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner.
Behavioural Brain Research,
348, 90-100.
https://doi.org/10.1016/j.bbr.2018.04.017
Olesen, M. S., Starnawska, A., Bybjerg-Grauholm, J., Bielfeld, A. P.
, Agerholm, I., Forman, A., Overgaard, M. T. & Nyegaard, M. (2018).
Biological age of the endometrium using DNA methylation.
Reproduction,
155(2), 165-170.
https://doi.org/10.1530/REP-17-0601
McKenzie, A. T., Wang, M.
, Hauberg, M. E., Fullard, J. F., Kozlenkov, A., Keenan, A., Hurd, Y. L., Dracheva, S., Casaccia, P., Roussos, P. & Zhang, B. (2018).
Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.
Scientific Reports,
8(1), Article 8868.
https://doi.org/10.1038/s41598-018-27293-5
Wong, D. F., Kuwabara, H., Horti, A. G., Roberts, J. M., Nandi, A., Cascella, N., Brasic, J., Weerts, E. M., Kitzmiller, K.
, Phan, J. A., Gapasin, L., Sawa, A., Valentine, H., Wand, G., Mishra, C., George, N., McDonald, M., Lesniak, W., Holt, D. P.
... Gjedde, A. (2018).
Brain PET imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia.
International Journal of Neuropsychopharmacology,
21(7), 656-667.
https://doi.org/10.1093/ijnp/pyy021
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J.
, Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018).
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice.
Scientific Reports,
8(1), 16486. Article 16486.
https://doi.org/10.1038/s41598-018-34729-5
Gao, S., Hu, X., Xu, F., Gao, C.
, Xiong, K., Zhao, X., Chen, H., Zhao, S., Wang, M., Fu, D., Zhao, X., Bai, J., Mao, L.
, Li, B., Wu, S., Wang, J., Li, S., Yang, H.
, Bolund, L. & Pedersen, C. N. S. (2018).
BS-virus-finder: virus integration calling using bisulfite sequencing data.
GigaScience,
7(1), 1-7.
https://doi.org/10.1093/gigascience/gix123