Peer-reviewed publications

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Andersen, N. S. B., Larsen, S. M., Nissen, S. K., Jørgensen, S. E., Mardahl, M., Christiansen, M., Kay, L. & Mogensen, T. H. (2019). Host genetics, innate immune responses, and cellular death pathways in poliomyelitis patients. Frontiers in Microbiology, 10, Article 1495. https://doi.org/10.3389/fmicb.2019.01495

Madsen, P., Isaksen, T. J., Siupka, P., Tóth, A. E., Nyegaard, M., Gustafsen, C. & Nielsen, M. S. (2019). HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA. Scientific Reports, 9, Article 611. https://doi.org/10.1038/s41598-018-37336-6

Hensel, N., Raker, V., Förthmann, B., Detering, N. T., Kubinski, S., Buch, A., Katzilieris-Petras, G., Spanier, J., Gudi, V., Wagenknecht, S., Kopfnagel, V., Werfel, T. A., Stangel, M., Beineke, A., Kalinke, U., Paludan, S. R., Sodeik, B. & Claus, P. (2019). HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0. Journal of Neuroinflammation, 16(1), Article 248. https://doi.org/10.1186/s12974-019-1647-5

Gomez-Ospina, N., Scharenberg, S. G., Mostrel, N., Bak, R. O., Mantri, S., Quadros, R. M., Gurumurthy, C. B., Lee, C., Bao, G., Suarez, C. J., Khan, S., Sawamoto, K., Tomatsu, S., Raj, N., Attardi, L. D., Aurelian, L. & Porteus, M. H. (2019). Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I. Nature Communications, 10(1), 4045. Article 4045. https://doi.org/10.1038/s41467-019-11962-8

Lafaille, F. G., Harschnitz, O., Lee, Y. S., Zhang, P., Hasek, M. L., Kerner, G., Itan, Y., Ewaleifoh, O., Rapaport, F., Carlile, T. M., Carter-Timofte, M. E., Paquet, D., Dobbs, K., Zimmer, B., Gao, D., Rojas-Duran, M. F., Kwart, D., Rattina, V., Ciancanelli, M. J. ... Zhang, S. Y. (2019). Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. Nature Medicine, 25(12), 1873-1884. https://doi.org/10.1038/s41591-019-0672-3

Steffensen, C., Dekkers, O. M., Lyhne, J., Pedersen, B. G., Rasmussen, F., Rungby, J., Poulsen, P. L. & Jørgensen, J. O. L. (2019). Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients. Hormone and Metabolic Research, 51(1), 62-68. https://doi.org/10.1055/a-0809-3647

Liou, A. Y., Molday, L. L., Wang, J., Andersen, J. P. & Molday, R. S. (2019). Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. Journal of Biological Chemistry, 294(17), 6809-6821. https://doi.org/10.1074/jbc.RA118.007270

de Groot, T., Ebert, L. K., Christensen, B. M., Andralojc, K., Cheval, L., Doucet, A., Mao, C., Baumgarten, R., Low, B. E., Sandhoff, R., Wiles, M. V., Deen, P. M. T. & Korstanje, R. (2019). Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice. Journal of the American Society of Nephrology : JASN, 30(12), 2322-2336. https://doi.org/10.1681/ASN.2018050549

Thomsen, M. M., Jørgensen, S. E., Storgaard, M., Kristensen, L. S., Gjedsted, J., Christiansen, M., Gad, H. H., Hartmann, R. & Mogensen, T. H. (2019). Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza. European Journal of Immunology, 49(11), 2111-2114. https://doi.org/10.1002/eji.201848083

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., Awashti, S., Belliveau, R., Bettella, F., Buxbaum, J. D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Christensen, J. H. ... Børglum, A. D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51(3), 431-444. https://doi.org/10.1038/s41588-019-0344-8

Kilian, M. & Tettelin, H. (2019). Identification of Virulence-Associated Properties by Comparative Genome Analysis of Streptococcus pneumoniae, S. pseudopneumoniae, S. mitis, Three S. oralis Subspecies, and S. infantis. mBio, 10(5), Article e01985-19. https://doi.org/10.1128/mBio.01985-19

Hotter, D., Bosso, M., Jønsson, K. L., Krapp, C., Stürzel, C. M., Das, A., Littwitz-Salomon, E., Berkhout, B., Russ, A., Wittmann, S., Gramberg, T., Zheng, Y., Martins, L. J., Planelles, V., Jakobsen, M. R., Hahn, B. H., Dittmer, U., Sauter, D. & Kirchhoff, F. (2019). IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation. Cell Host & Microbe, 25(6), 858-872.e13. https://doi.org/10.1016/j.chom.2019.05.002

Kragstrup, T. W., Adams, M., Lomholt, S., Nielsen, M. A., Heftdal, L. D., Schafer, P. & Deleuran, B. (2019). IL-12/IL-23p40 identified as a downstream target of apremilast in ex vivo models of arthritis. Therapeutic Advances in Musculoskeletal Disease, 11. https://doi.org/10.1177/1759720X19828669

Vu-Quang, H., Vinding, M. S., Jakobsen, M., Song, P., Dagnaes-Hansen, F., Nielsen, N. C. & Kjems, J. (2019). Imaging rheumatoid arthritis in mice using combined near infrared and ¹⁹F magnetic resonance modalities. Scientific Reports, 9, Article 14314. https://doi.org/10.1038/s41598-019-50043-0

Charlton, J. R., Harer, M. W., Swan, C. & Nielsen, R. (2019). Immature megalin expression in the preterm neonatal kidney is associated with urinary loss of vitamin carrier proteins. Pediatric Research, 85(3), 405-411. https://doi.org/10.1038/s41390-018-0261-z

Tansey, M. G. & Romero-Ramos, M. (2019). Immune system responses in Parkinson's Disease: early and dynamic. The European journal of neuroscience, 49(3), 364-383. https://doi.org/10.1111/ejn.14290

Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, M., Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, T., Rasmussen, S. & Thompson, W. K. (2019). Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders. European Journal of Human Genetics, 27(9), 1445-1455. https://doi.org/10.1038/s41431-019-0402-9

Lausen, M., Christiansen, G., Guldbæk Poulsen, T. B. & Birkelund, S. (2019). Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection. Microbes and Infection, 21(2), 73-84. https://doi.org/10.1016/j.micinf.2018.10.007

Su, J., Hughes, A. D., Simonsen, U., Nielsen-Kudsk, J. E., Parker, K. H., Howard, L. S. & Mellemkjaer, S. (2019). Impact of Pulmonary Endarterectomy on Pulmonary Arterial Wave Propagation and Reservoir Function. American Journal of Physiology: Heart and Circulatory Physiology, 317(3), H505-H516. https://doi.org/10.1152/ajpheart.00181.2019

Mardahl, M., Jørgensen, S. E., Schneider, A., Raaschou-Jensen, K., Holm, M., Veirum, J., Kristensen, T. K., Johansen, I. S., Christiansen, M., Assing, K. & Mogensen, T. H. (2019). Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC. British Journal of Haematology, 186(3), 471-476. https://doi.org/10.1111/bjh.15947

Rasmussen, C. B., Christiansen, G., Vad, B. S., Lynggaard, C., Enghild, J. J., Andreasen, M. & Otzen, D. (2019). Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation. Protein Science, 28(3), 633-642. https://doi.org/10.1002/pro.3566

Jensen, T. B., Bartels, D., Sædder, E. A., Poulsen, B. K., Andersen, S. E., Christensen, M. M. H., Nielsen, L. & Christensen, H. R. (2019). Implementation of TNF-biosimilars (Infliximab and Eternacept) in Danish departments of rheumatology. Annals of the Rheumatic Diseases, 78(Suppl. 2), 237-237. Article OP0310. https://doi.org/10.1136/annrheumdis-2019-eular.1383

Moosa, S., Gregersen, P. A., Hald, J. D. & Vogel, I. (2019). Implications of identifying a PLS3 deletion as an incidental finding on prenatal testing. Poster session presented at The 14th biannual International Skeletal Dysplasia Society Meeting , Oslo.

Hagensen, M. K., Mortensen, M. B., Kjolby, M., Palmfeldt, J., Bentzon, J. F. & Gregersen, S. (2019). Increased retention of LDL from type 1 diabetic patients in atherosclerosis-prone areas of the murine arterial wall. Atherosclerosis, 286, 156-162. https://doi.org/10.1016/j.atherosclerosis.2019.02.027

El-Akkawi, A. I., de Paoli, F. V., Bendixen, M. & Christensen, T. D. (2019). Indication and timing of surgery are essential in stabilization of the chest wall in flail chest trauma patients. Abstract from 29th Annual Meeting SSRCTS, Geilo, Norway.

Skovdal, S. M., Christiansen, S. H., Johansen, K. S., Viborg, O., Bruun, N. H., Jensen-Fangel, S., Holm, I. E., Vorup-Jensen, T. & Petersen, E. (2019). Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs. PLOS ONE, 14(10), Article e0223647. https://doi.org/10.1371/journal.pone.0223647

Zhou, Y., Jones, N. C., Pedersen, J. N., Perez, B., Hoffmann, S. V., Petersen, S. V., Pedersen, J. S., Perriman, A., Kristensen, P., Gao, R. & Guo, Z. (2019). Insight into the structure and activity of surface-engineered lipase biofluids. ChemBioChem, 20(10), 1266-1272. https://doi.org/10.1002/cbic.201800819

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10, Article 2548. https://doi.org/10.1038/s41467-019-10461-0

Zhang, W., Voloudakis, G., Rajagopal, V. M., Readhead, B., Dudley, J. T., Schadt, E. E., Björkegren, J. L. M., Kim, Y., Fullard, J. F., Hoffman, G. E. & Roussos, P. (2019). Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits. Nature Communications, 10(1), 1-13. Article 3834. https://doi.org/10.1038/s41467-019-11874-7

Nandakumar, R., Windross, S. J. & Paludan, S. R. (2019). Intercellular communication in the innate immune system through the cGAS-STING pathway. In J. Sohn (Ed.), DNA Sensors and Inflammasomes (pp. 1-11). Elsevier. https://doi.org/10.1016/bs.mie.2019.07.007

Kaleviste, E., Saare, M., Leahy, T. R., Bondet, V., Duffy, D., Mogensen, T. H., Jørgensen, S. E., Nurm, H., Ip, W., Davies, E. G., Sauer, S., Syvänen, A. C., Milani, L., Peterson, P. & Kisand, K. (2019). Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined. European Journal of Immunology, 49(5), 790-800. https://doi.org/10.1002/eji.201847955

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M. ... Koenen, K. C. (2019). International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications, 10(1), Article 4558. https://doi.org/10.1038/s41467-019-12576-w

Wittenborn, T. R., Hagert, C. & Degn, S. E. (2019). Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity. Journal of visualized experiments : JoVE, 2019(146), Article e59397. https://doi.org/10.3791/59397

Nandakumar, R., Tschismarov, R., Meissner, F., Prabakaran, T., Krissanaprasit, A., Farahani, E., Zhang, B. C., Assil, S., Martin, A., Bertrams, W., Holm, C. K., Ablasser, A., Klause, T., Thomsen, M. K., Schmeck, B., Howard, K. A., Henry, T., Gothelf, K. V., Decker, T. & Paludan, S. R. (2019). Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling. Nature Microbiology, 4, 701-713. https://doi.org/10.1038/s41564-019-0367-z

Kaspersen, A. E., Hasenkam, J. M., Leipziger, J. G. & Djurhuus, J. C. (2019). Introduktion til at skrive et videnskabeligt abstract. Ugeskrift for Læger, 181(21), Article V02190103. http://ugeskriftet.dk/videnskab/introduktion-til-skrive-et-videnskabeligt-abstract

Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019). Investigating the association between body fat and depression via Mendelian randomization. Translational Psychiatry, 9(1), Article 184. https://doi.org/10.1038/s41398-019-0516-4

Speed, D., Hemani, G., Speed, M. S., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Børglum, A. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica, 139(4), 395-397. https://doi.org/10.1111/acps.13009

Weingart, O. G., Eyer, K., Lüchtenborg, C., Sachsenheimer, T., Brügger, B., Van Oostrum, M., Wollscheid, B., Dittrich, P. S. & Loessner, M. J. (2019). In vitro quantification of botulinum neurotoxin type A1 using immobilized nerve cell-mimicking nanoreactors in a microfluidic platform. Analyst, 144(19), 5755-5765. https://doi.org/10.1039/c9an00817a

Staehr, C., Rajanathan, R. & Matchkov, V. V. (2019). Involvement of the Na ⁺ ,K ⁺-ATPase isoforms in control of cerebral perfusion. Experimental Physiology, 104(7), 1023-1028. https://doi.org/10.1113/EP087519

Mogensen, T. H. (2019). IRF and STAT transcription factors - From basic biology to roles in infection, protective immunity, and primary immunodeficiencies. Frontiers in Immunology, 9, Article 3047. https://doi.org/10.3389/fimmu.2018.03047

Alstrup, T., Eijken, M., Bohn, A. B., Møller, B. & Damsgaard, T. E. (2019). Isolation of Adipose Tissue-Derived Stem Cells: Enzymatic Digestion in Combination with Mechanical Distortion to Increase Adipose Tissue-Derived Stem Cell Yield from Human Aspirated Fat. Current protocols in stem cell biology, 48(1), Article e68. https://doi.org/10.1002/cpsc.68

Poulsen, S. B. & Fenton, R. A. (2019). K+ and the renin-angiotensin-aldosterone system: new insights into their role in blood pressure control and hypertension treatment. The Journal of Physiology, 597(17), 4451-4464. https://doi.org/10.1113/JP276844

Fredslund, S. O., Gravholt, C. H., Laursen, B. E. & Jensen, A. B. (2019). Key metabolic parameters change significantly in early breast cancer survivors: An explorative PILOT study. Journal of Translational Medicine, 17(1), Article 105. https://doi.org/10.1186/s12967-019-1850-2

King, D., Glynn, M. D., Cindric, S., Kernan, D., O’Connell, T., Hakimjavadi, R., Kearney, S., Ackermann, T., Berbel, X. M., Llobera, A., Simonsen, U., Laursen, B. E., Redmond, E. M., Cahill, P. A. & Ducrée, J. (2019). Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform. Scientific Reports, 9, Article 4157. https://doi.org/10.1038/s41598-019-40612-8

Therkildsen, J. R., Christensen, M. G., Tingskov, S. J., Wehmöller, J., Nørregaard, R. & Praetorius, H. A. (2019). Lack of P2X ₇ Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin–Producing Escherichia coli. American Journal of Pathology, 189(6), 1201-1211. https://doi.org/10.1016/j.ajpath.2019.02.013

Larsen, J. B., Andersen, A. S., Hvas, C. L., Thiel, S., Lassen, M. R., Hvas, A.-M. & Hansen, A. T. (2019). Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia. American Journal of Reproductive Immunology Online, 81(4), e13092. Article e13092. https://doi.org/10.1111/aji.13092

M'kacher, R., Junker, S., Jeandidier, E. & Carde, P. (2019). Letter to the editor of environmental and molecular mutagenesis: In regard to Ramos et al. Environmental and Molecular Mutagenesis, 60(4), 385-386. https://doi.org/10.1002/em.22282

Xiang, X., Luo, L., Nodzyński, M., Li, C., Han, P., Dou, H., Petersen, T. S., Liang, X., Pan, X., Qu, K., Yang, L., Dang, Y., Liu, X., Bolund, L., Zhang, X., Tong, G., Xing, Y., Luo, Y. & Lin, L. (2019). LION: a simple and rapid method to achieve CRISPR gene editing. Cellular and Molecular Life Sciences, 76(13), 2633-2645. https://doi.org/10.1007/s00018-019-03064-x

Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019). Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy, 27(8), 1424-1435. https://doi.org/10.1016/j.ymthe.2019.05.002

Andersen, M. A., Sotty, F., Jensen, P. H., Badolo, L., Jeggo, R., Smith, G. P. & Christensen, K. V. (2019). Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications. eNeuro , 6(6), Article ENEURO.0453-18.2019. https://doi.org/10.1523/ENEURO.0453-18.2019

Displaying results 2401 to 2450 out of 10727

Revised 14.09.2020