Olesen, A. E., Schacksen, C. S., Nielsen, I. M.
, Nielsen, L. P., Andersen, S.
& Andersen, C. U. (2022).
Significantly higher use of polypharmacy in elderly with hip fracture treated with psychotropics.
Danish Medical Journal,
69(10), Article A12210945.
Kalaee, S. A., Lindholm, A. B., Haldrup, J., Jensen, E. G., Mikkelsen, J. G., Aagaard, L., Askou, A. L. & Corydon, T. J. (2022).
Simple Autofluorescence-Restrictive Sorting of eGFP+ RPE Cells Allows Reliable Assessment of Targeted Retinal Gene Therapy.
Frontiers in Drug Delivery,
2, Article 898568.
https://doi.org/10.3389/fddev.2022.898568
Wen, J., Cao, T., Wu, J., Chen, Y., Zhi, S., Huang, Y., Zhen, P., Wu, G.
, Aagaard, L., Zhong, J., Liang, P. & Huang, J. (2022).
Single AAV-mediated CRISPR-Nme2Cas9 efficiently reduces mutant hTTR expression in a transgenic mouse model of transthyretin amyloidosis.
Molecular Therapy,
30(1), 164-174.
https://doi.org/10.1016/j.ymthe.2021.05.010
Geldhof, V., de Rooij, L. P. M. H., Sokol, L., Amersfoort, J., De Schepper, M., Rohlenova, K., Hoste, G., Vanderstichele, A., Delsupehe, A. M., Isnaldi, E., Dai, N., Taverna, F., Khan, S., Truong, A. C. K., Teuwen, L. A., Richard, F., Treps, L., Smeets, A., Nevelsteen, I.
... Carmeliet, P. (2022).
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.
Nature Communications,
13, Article 5511.
https://doi.org/10.1038/s41467-022-33052-y
Thomsen, E. A., Andersen, S., Marqvorsen, M. H. S., Skipper, K. A., Paludan, S. R. & Mikkelsen, J. G. (2022).
Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression.
Frontiers in cellular and infection microbiology,
11, Article 784762.
https://doi.org/10.3389/fcimb.2021.784762
Jovic, D., Liang, X., Zeng, H.
, Lin, L., Xu, F.
& Luo, Y. (2022).
Single-cell RNA sequencing technologies and applications: A brief overview.
Clinical and Translational Medicine,
12(3), Article e694.
https://doi.org/10.1002/ctm2.694
Costanzo, V., D’Apolito, L.
, Sardella, D., Iervolino, A., La Manna, G., Capasso, G.
, Frische, S. & Trepiccione, F. (2022).
Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture.
Pflügers Archiv - European Journal of Physiology,
474(7), 733-741.
https://doi.org/10.1007/s00424-022-02686-8
Pedersen, A. K. N., Hage, C.
, Jessen, N., Mellbin, L.
& Bjerre, M. (2022).
Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities.
Molecular and Cellular Endocrinology,
556, Article 111738.
https://doi.org/10.1016/j.mce.2022.111738
Stødkilde, K., Nielsen, J. T., Petersen, S. V., Paetzold, B.
, Brüggemann, H., Mulder, F. A. A. & Andersen, C. B. F. (2022).
Solution Structure of the Cutibacterium acnes-Specific Protein RoxP and Insights Into Its Antioxidant Activity.
Frontiers in cellular and infection microbiology,
12, Article 803004.
https://doi.org/10.3389/fcimb.2022.803004
Shih, A. Z. L., Chen, Y. C., Speckmann, T.
, Søndergaard, E., Schürmann, A., Verchere, C. B.
& Willnow, T. E. (2022).
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition.
Molecular Metabolism,
65, Article 101585.
https://doi.org/10.1016/j.molmet.2022.101585
Ulrichsen, M., Gonçalves, N. P., Mohseni, S., Hjæresen, S., Lisle, T. L.
, Molgaard, S., Madsen, N. K., Andersen, O. M., Svenningsen, Å. F.
, Glerup, S., Nykjær, A. & Vægter, C. B. (2022).
Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury.
Frontiers in Cellular Neuroscience,
16, Article 856734.
https://doi.org/10.3389/fncel.2022.856734
Toth, A. E., Helms, H. C.
, Harazin, A., Johnsen, K. B., Goldeman, C., Burkhart, A., Thomsen, M. S., Kempen, P. J.
, Klepe, A., Lipka, D. V., Møller, P. L., Andresen, T. L.
, Nyegaard, M., Moos, T., Brodin, B.
& Nielsen, M. S. (2022).
Sortilin regulates blood-brain barrier integrity.
FEBS journal,
289(4), 1062-1079.
https://doi.org/10.1111/febs.16225
Srivastava, P., de Rosenroll, G.
, Matsumoto, A., Michaels, T., Turple, Z., Jain, V., Sethuramanujam, S., Murphy-Baum, B. L.
, Yonehara, K. & Awatramani, G. B. (2022).
Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells.
eLife,
11, Article e81533.
https://doi.org/10.7554/eLife.81533
Andersen, M. N., Andersen, N. F., Lauridsen, K. L., Etzerodt, A., Sorensen, B. S., Abildgaard, N.
, Plesner, T., Hokland, M. & Møller, H. J. (2022).
STAT3 is over-activated within CD163pos bone marrow macrophages in both Multiple Myeloma and the benign pre-condition MGUS.
Cancer Immunology, Immunotherapy,
71(1), 177-187.
https://doi.org/10.1007/s00262-021-02952-1
Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R.
, Grove, J., Fu, J. M., Nadig, A., Carey, C. E., Baya, N., Bybjerg-Grauholm, J., iPSYCH Consortium, ASD Working Group of the Psychiatric Genomics Consortium, ADHD Working Group of the Psychiatric Genomics Consortium, Berretta, S., Macosko, E. Z., Sebat, J., O'Connor, L. J., Hougaard, D. M. ... Robinson, E. B. (2022).
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p.
Nature Genetics,
54(11), 1630-1639.
https://doi.org/10.1038/s41588-022-01203-y
Vila, I. K., Chamma, H., Steer, A., Saccas, M., Taffoni, C., Turtoi, E.
, Reinert, L. S., Hussain, S., Marines, J., Jin, L., Bonnefont, X., Hubert, M., Schwartz, O.
, Paludan, S. R., Van Simaeys, G., Doumont, G., Sobhian, B., Vlachakis, D., Turtoi, A. & Laguette, N. (2022).
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Cell Metabolism,
34(1), 125-139.e8.
https://doi.org/10.1016/j.cmet.2021.12.007
Andersen, M., Smith, B.
, Murra, M., Nielsen, S. Y., Slotved, H.-C.
& Henriksen, T. B. (2022).
Strains of Group B Streptococcus (Streptococcus Agalactiae) and their clinical course in early and late onset infant disease. In
Abstract volume (pp. 659-660). Frontiers in Pediatrics.
https://doi.org/10.3389/978-2-88971-024-9
Jensen, R. K., Pedersen, H., Lorentzen, J., Laursen, N. S., Vorup-Jensen, T. & Andersen, G. R. (2022).
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2.
Journal of Biological Chemistry,
298(8), Article 102168.
https://doi.org/10.1016/j.jbc.2022.102168
Le, L. T. M., Drakulic, S., Nyengaard, J. R., Golas, M. M. & Sander, B. (2022).
Structural Organization of Human Full-Length PAR3 and the aPKC–PAR6 Complex.
Molecular Biotechnology,
64(12), 1319-1327.
https://doi.org/10.1007/s12033-022-00504-1
Pedersen, H., Jensen, R. K., Hansen, A. G., Petersen, S. V., Thiel, S., Laursen, N. S. & Andersen, G. R. (2022).
Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity.
Frontiers in Immunology,
13, Article 872536.
https://doi.org/10.3389/fimmu.2022.872536
Brodin, P., Casari, G., Townsend, L., O’Farrelly, C., Tancevski, I., Löffler-Ragg, J.
, Mogensen, T. H., Casanova, J. L. & The COVID Human Genetic Effort (2022).
Studying severe long COVID to understand post-infectious disorders beyond COVID-19.
Nature Medicine,
28, 879-882.
https://doi.org/10.1038/s41591-022-01766-7
Leegaard, A., Gregersen, P. A., Nielsen, T., Bjerre, J. V. & Handrup, M. M. (2022).
Succesful MEK-inhibition of severe hypertrophic cardiomyopathy in RIT1-related Noonan Syndrome.
European Journal of Medical Genetics,
65(11), Article 104630.
https://doi.org/10.1016/j.ejmg.2022.104630
Zhou, Y., Pedersen, J. N., Pedersen, J. N., Jones, N. C., Hoffmann, S. V., Petersen, S. V., Pedersen, J. S., Perriman, A., Gao, R.
& Guo, Z. (2022).
Superanionic Solvent-Free Liquid Enzymes Exhibit Enhanced Structures and Activities.
Advanced Science,
9(32), Article 2202359.
https://doi.org/10.1002/advs.202202359
Butt, L., Unnersjö-Jess, D., Höhne, M., Hahnfeldt, R., Reilly, D.
, Rinschen, M., Plagmann, I., Diefenhardt, P., Braehler, S., Brinkkötter, P., Brismar, H., Blom, H., Schermer, B. & Benzing, T. (2022).
Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease.
Journal of the American Society of Nephrology : JASN,
33(1), 138-154.
https://doi.org/10.1681/ASN.2020060858
Guillot, J., Dominici, C., Lucchesi, A., Nguyen, H. T. T., Puget, A., Hocine, M., Rangel-Sosa, M. M., Simic, M., Nigri, J., Guillaumond, F., Bigonnet, M., Dusetti, N., Perrot, J., Lopez, J.
, Etzerodt, A., Lawrence, T., Pudlo, P., Hubert, F., Scoazec, J.-Y. ... Mann, F. (2022).
Sympathetic axonal sprouting induces changes in macrophage populations and protects against pancreatic cancer.
Nature Communications,
13(1), Article 1985.
https://doi.org/10.1038/s41467-022-29659-w
Murphy, R. A., Coates, M.
, Thrane, S., Sabnis, A., Harrison, J., Schelenz, S., Edwards, A. M.
, Vorup-Jensen, T. & Davies, J. C. (2022).
Synergistic Activity of Repurposed Peptide Drug Glatiramer Acetate with Tobramycin against Cystic Fibrosis Pseudomonas aeruginosa.
Microbiology Spectrum,
10(4), Article e00813-22.
https://doi.org/10.1128/spectrum.00813-22
Hølmkjær, P., Vermehren, C., Holm, A., Rozing, M. P.
, Høj, K. & Overbeck, G. (2022).
Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia.
BMC Health Services Research,
22(1), Article 1582.
https://doi.org/10.1186/s12913-022-08961-9
Skejoe, C., Hansen, A. S., Stengaard-Pedersen, K., Junker, P., Hoerslev-Pedersen, K., Hetland, M. L., Oestergaard, M.
, Greisen, S., Hvid, M., Deleuran, M. & Deleuran, B. (2022).
T-cell immunoglobulin and mucin domain 3 is upregulated in rheumatoid arthritis, but insufficient in controlling inflammation.
American Journal of Clinical and Experimental Immunology,
11(3), 34-44.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301058/pdf/ajcei0011-0034.pdf
Illum, L. R. H., Forman, A., Melgaard, A., Hansen, K. E., Hansen, S. N., Nyegaard, M., Hummelshoj, L.
& Rytter, D. (2022).
Temporal and regional differences in the incidence of hospital-diagnosed endometriosis: a Danish population-based study.
Acta Obstetricia et Gynecologica Scandinavica,
101(7), 737-746.
https://doi.org/10.1111/aogs.14364
Mishra, S., Knupp, A., Szabo, M. P., Williams, C. A., Kinoshita, C., Hailey, D. W., Wang, Y.
, Andersen, O. M. & Young, J. E. (2022).
The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons.
Cellular and Molecular Life Sciences,
79(3), Article 162.
https://doi.org/10.1007/s00018-022-04182-9
Mühlig, A. K., Steingröver, J., Heidelbach, H. S., Wingerath, M., Sachs, W., Hermans-Borgmeyer, I., Meyer-Schwesinger, C., Choi, H. Y., Lim, B. J., Patry, C., Hoffmann, G. F., Endlich, N., Bracke, K., Weiß, M., Guse, A. H., Lassé, M.
, Rinschen, M., Braun, F., Huber, T. B. ... Oh, J. (2022).
The Calcium-Sensing Receptor Stabilizes Podocyte Function in Proteinuric Humans and Mice.
Kidney International,
101(6), 1186-1199.
https://doi.org/10.1016/j.kint.2022.01.036
Baran, R., Marchal, S., Campos, S. G., Rehnberg, E., Tabury, K., Baselet, B.
, Wehland, M., Grimm, D. & Baatout, S. (2022).
The Cardiovascular System in Space: Focus on In Vivo and In Vitro Studies.
Biomedicines,
10(1), Article 59.
https://doi.org/10.3390/biomedicines10010059
Kuiper, E. F. E., Gallardo, P., Bergsma, T.
, Mari, M., Kolbe Musskopf, M., Kuipers, J., Giepmans, B. N. G., Steen, A., Kampinga, H. H., Veenhoff, L. M. & Bergink, S. (2022).
The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis.
Nature Cell Biology,
24(11), 1584-1594.
https://doi.org/10.1038/s41556-022-01010-x
Farzadfard, A., Pedersen, J. N., Meisl, G.
, Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J.
, Pedersen, J. S. & Otzen, D. E. (2022).
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
Communications Biology,
5(1), 123. Article 123.
https://doi.org/10.1038/s42003-022-03059-8
Rosenbaek, L., Petrillo, F., Van Bemmelen, M., Staub, O.
, Murali, S. & Fenton, R. (2022).
The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter (NCC) but is not required for a potassium-induced reduction of NCC expression.
The FASEB Journal,
36(S1).
https://doi.org/10.1096/fasebj.2022.36.S1.0R831
Rosenbaek, L. L., Petrillo, F., van Bemmelen, M. X., Staub, O.
, Murali, S. K. & Fenton, R. A. (2022).
The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression.
Frontiers in Physiology,
13, Article 971251.
https://doi.org/10.3389/fphys.2022.971251
Ahring, K. K.
, Dagnæs-Hansen, F., Brüel, A., Christensen, M.
, Jensen, E., Jensen, T. G., Johannsen, M., Johansen, K. S., Lund, A. M.
, Madsen, J. G., Brøndum-Nielsen, K.
, Pedersen, M., Sørensen, L. K., Kjolby, M. & Møller, L. B. (2022).
The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model.
PLOS ONE,
17(1), Article e0261150.
https://doi.org/10.1371/journal.pone.0261150
Voss, L. F., Howarth, A. J., Wittenborn, T. R., Hummelgaard, S., Juul-Madsen, K., Kastberg, K. S., Pedersen, M. K.
, Jensen, L., Papanastasiou, A. D.
, Vorup-Jensen, T., Weyer, K. & Degn, S. E. (2022).
The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus.
Frontiers in Immunology,
13, Article 1021370.
https://doi.org/10.3389/fimmu.2022.1021370
Wigdor, E. M., Weiner, D. J.
, Grove, J., Fu, J. M.
, Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M.
, Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022).
The female protective effect against autism spectrum disorder.
Cell Genomics,
2(6), Article 100134.
https://doi.org/10.1016/j.xgen.2022.100134
Grimm, D., Schulz, H., Krüger, M., Cortés-Sánchez, J. L., Egli, M., Kraus, A.
, Sahana, J., Corydon, T. J., Hemmersbach, R., Wise, P. M., Infanger, M.
& Wehland, M. (2022).
The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model.
International Journal of Molecular Sciences ,
23(6), Article 3073.
https://doi.org/10.3390/ijms23063073
Mahjani, B., Klei, L.
, Mattheisen, M., Halvorsen, M. W., Reichenberg, A., Roeder, K., Pedersen, N. L., Boberg, J., de Schipper, E., Bulik, C. M., Landén, M., Fundín, B., Mataix-Cols, D., Sandin, S., Hultman, C. M., Crowley, J. J., Buxbaum, J. D., Rück, C., Devlin, B. & Grice, D. E. (2022).
The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum.
American Journal of Psychiatry,
179(3), 216-225.
https://doi.org/10.1176/appi.ajp.2021.21010101
Arjmand, S., Landau, A. M., Varastehmoradi, B., Andreatini, R.
, Joca, S. & Wegener, G. (2022).
The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants.
Molecular Psychiatry,
27(8), 3138–3149 .
https://doi.org/10.1038/s41380-022-01598-4