Peer-reviewed publications

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Le, L. T. M., Drakulic, S., Nyengaard, J. R., Golas, M. M. & Sander, B. (2022). Structural Organization of Human Full-Length PAR3 and the aPKC–PAR6 Complex. Molecular Biotechnology, 64(12), 1319-1327. https://doi.org/10.1007/s12033-022-00504-1

Fedosova, N., Habeck, M. & Nissen, P. (2022). Structure and Function of Na,K-ATPase-The Sodium-Potassium Pump. Comprehensive Physiology, 12(1), 2659-2679.

Pedersen, H., Jensen, R. K., Hansen, A. G., Petersen, S. V., Thiel, S., Laursen, N. S. & Andersen, G. R. (2022). Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity. Frontiers in Immunology, 13, Article 872536. https://doi.org/10.3389/fimmu.2022.872536

Brodin, P., Casari, G., Townsend, L., O’Farrelly, C., Tancevski, I., Löffler-Ragg, J., Mogensen, T. H., Casanova, J. L. & The COVID Human Genetic Effort (2022). Studying severe long COVID to understand post-infectious disorders beyond COVID-19. Nature Medicine, 28, 879-882. https://doi.org/10.1038/s41591-022-01766-7

Leegaard, A., Gregersen, P. A., Nielsen, T., Bjerre, J. V. & Handrup, M. M. (2022). Succesful MEK-inhibition of severe hypertrophic cardiomyopathy in RIT1-related Noonan Syndrome. European Journal of Medical Genetics, 65(11), Article 104630. https://doi.org/10.1016/j.ejmg.2022.104630

Zhou, Y., Pedersen, J. N., Pedersen, J. N., Jones, N. C., Hoffmann, S. V., Petersen, S. V., Pedersen, J. S., Perriman, A., Gao, R. & Guo, Z. (2022). Superanionic Solvent-Free Liquid Enzymes Exhibit Enhanced Structures and Activities. Advanced Science, 9(32), Article 2202359. https://doi.org/10.1002/advs.202202359

Butt, L., Unnersjö-Jess, D., Höhne, M., Hahnfeldt, R., Reilly, D., Rinschen, M., Plagmann, I., Diefenhardt, P., Braehler, S., Brinkkötter, P., Brismar, H., Blom, H., Schermer, B. & Benzing, T. (2022). Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease. Journal of the American Society of Nephrology : JASN, 33(1), 138-154. https://doi.org/10.1681/ASN.2020060858

Guillot, J., Dominici, C., Lucchesi, A., Nguyen, H. T. T., Puget, A., Hocine, M., Rangel-Sosa, M. M., Simic, M., Nigri, J., Guillaumond, F., Bigonnet, M., Dusetti, N., Perrot, J., Lopez, J., Etzerodt, A., Lawrence, T., Pudlo, P., Hubert, F., Scoazec, J.-Y. ... Mann, F. (2022). Sympathetic axonal sprouting induces changes in macrophage populations and protects against pancreatic cancer. Nature Communications, 13(1), Article 1985. https://doi.org/10.1038/s41467-022-29659-w

Murphy, R. A., Coates, M., Thrane, S., Sabnis, A., Harrison, J., Schelenz, S., Edwards, A. M., Vorup-Jensen, T. & Davies, J. C. (2022). Synergistic Activity of Repurposed Peptide Drug Glatiramer Acetate with Tobramycin against Cystic Fibrosis Pseudomonas aeruginosa. Microbiology Spectrum, 10(4), Article e00813-22. https://doi.org/10.1128/spectrum.00813-22

Hølmkjær, P., Vermehren, C., Holm, A., Rozing, M. P., Høj, K. & Overbeck, G. (2022). Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia. BMC Health Services Research, 22(1), Article 1582. https://doi.org/10.1186/s12913-022-08961-9

Skejoe, C., Hansen, A. S., Stengaard-Pedersen, K., Junker, P., Hoerslev-Pedersen, K., Hetland, M. L., Oestergaard, M., Greisen, S., Hvid, M., Deleuran, M. & Deleuran, B. (2022). T-cell immunoglobulin and mucin domain 3 is upregulated in rheumatoid arthritis, but insufficient in controlling inflammation. American Journal of Clinical and Experimental Immunology, 11(3), 34-44. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301058/pdf/ajcei0011-0034.pdf

Illum, L. R. H., Forman, A., Melgaard, A., Hansen, K. E., Hansen, S. N., Nyegaard, M., Hummelshoj, L. & Rytter, D. (2022). Temporal and regional differences in the incidence of hospital-diagnosed endometriosis: a Danish population-based study. Acta Obstetricia et Gynecologica Scandinavica, 101(7), 737-746. https://doi.org/10.1111/aogs.14364

Mishra, S., Knupp, A., Szabo, M. P., Williams, C. A., Kinoshita, C., Hailey, D. W., Wang, Y., Andersen, O. M. & Young, J. E. (2022). The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons. Cellular and Molecular Life Sciences, 79(3), Article 162. https://doi.org/10.1007/s00018-022-04182-9

Mühlig, A. K., Steingröver, J., Heidelbach, H. S., Wingerath, M., Sachs, W., Hermans-Borgmeyer, I., Meyer-Schwesinger, C., Choi, H. Y., Lim, B. J., Patry, C., Hoffmann, G. F., Endlich, N., Bracke, K., Weiß, M., Guse, A. H., Lassé, M., Rinschen, M., Braun, F., Huber, T. B. ... Oh, J. (2022). The Calcium-Sensing Receptor Stabilizes Podocyte Function in Proteinuric Humans and Mice. Kidney International, 101(6), 1186-1199. https://doi.org/10.1016/j.kint.2022.01.036

Mohammad, G. S., Joca, S. & Starnawska, A. (2022). The Cannabis-Induced Epigenetic Regulation of Genes Associated with Major Depressive Disorder. Genes, 13(8), Article 1435. https://doi.org/10.3390/genes13081435

Baran, R., Marchal, S., Campos, S. G., Rehnberg, E., Tabury, K., Baselet, B., Wehland, M., Grimm, D. & Baatout, S. (2022). The Cardiovascular System in Space: Focus on In Vivo and In Vitro Studies. Biomedicines, 10(1), Article 59. https://doi.org/10.3390/biomedicines10010059

Kuiper, E. F. E., Gallardo, P., Bergsma, T., Mari, M., Kolbe Musskopf, M., Kuipers, J., Giepmans, B. N. G., Steen, A., Kampinga, H. H., Veenhoff, L. M. & Bergink, S. (2022). The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis. Nature Cell Biology, 24(11), 1584-1594. https://doi.org/10.1038/s41556-022-01010-x

Elbæk Mistegård, C. & Proft, F. (2022). The Complement System in Spondyloarthritis: What Do We Know? touchREVIEWS in RMD, 2(1), 50-56. https://doi.org/10.17925/RMD.2022.1.2.50

Farzadfard, A., Pedersen, J. N., Meisl, G., Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J., Pedersen, J. S. & Otzen, D. E. (2022). The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization. Communications Biology, 5(1), 123. Article 123. https://doi.org/10.1038/s42003-022-03059-8

Rosenbaek, L., Petrillo, F., Van Bemmelen, M., Staub, O., Murali, S. & Fenton, R. (2022). The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter (NCC) but is not required for a potassium-induced reduction of NCC expression. The FASEB Journal, 36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.0R831

Rosenbaek, L. L., Petrillo, F., van Bemmelen, M. X., Staub, O., Murali, S. K. & Fenton, R. A. (2022). The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression. Frontiers in Physiology, 13, Article 971251. https://doi.org/10.3389/fphys.2022.971251

Elmholt, S. B., Hede, K. C., Christensen, B. B., Thomsen, J. S. & Lind, M. (2022). The Effect of Bone Marrow Stimulation for Cartilage Repair on the Subchondral Bone Plate. Cartilage, 13(1). https://doi.org/10.1177/19476035221074011

Ahring, K. K., Dagnæs-Hansen, F., Brüel, A., Christensen, M., Jensen, E., Jensen, T. G., Johannsen, M., Johansen, K. S., Lund, A. M., Madsen, J. G., Brøndum-Nielsen, K., Pedersen, M., Sørensen, L. K., Kjolby, M. & Møller, L. B. (2022). The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model. PLoS One, 17(1), Article e0261150. https://doi.org/10.1371/journal.pone.0261150

Kristensen, L. S., Jakobsen, T., Hager, H. & Kjems, J. (2022). The emerging roles of circRNAs in cancer and oncology. Nature Reviews. Clinical Oncology, 19(3), 188-206. https://doi.org/10.1038/s41571-021-00585-y

Voss, L. F., Howarth, A. J., Wittenborn, T. R., Hummelgaard, S., Juul-Madsen, K., Kastberg, K. S., Pedersen, M. K., Jensen, L., Papanastasiou, A. D., Vorup-Jensen, T., Weyer, K. & Degn, S. E. (2022). The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus. Frontiers in Immunology, 13, Article 1021370. https://doi.org/10.3389/fimmu.2022.1021370

Wigdor, E. M., Weiner, D. J., Grove, J., Fu, J. M., Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M., Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022). The female protective effect against autism spectrum disorder. Cell Genomics, 2(6), Article 100134. https://doi.org/10.1016/j.xgen.2022.100134

Grimm, D., Schulz, H., Krüger, M., Cortés-Sánchez, J. L., Egli, M., Kraus, A., Sahana, J., Corydon, T. J., Hemmersbach, R., Wise, P. M., Infanger, M. & Wehland, M. (2022). The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model. International Journal of Molecular Sciences , 23(6), Article 3073. https://doi.org/10.3390/ijms23063073

Mahjani, B., Klei, L., Mattheisen, M., Halvorsen, M. W., Reichenberg, A., Roeder, K., Pedersen, N. L., Boberg, J., de Schipper, E., Bulik, C. M., Landén, M., Fundín, B., Mataix-Cols, D., Sandin, S., Hultman, C. M., Crowley, J. J., Buxbaum, J. D., Rück, C., Devlin, B. & Grice, D. E. (2022). The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. American Journal of Psychiatry, 179(3), 216-225. https://doi.org/10.1176/appi.ajp.2021.21010101

Arjmand, S., Landau, A. M., Varastehmoradi, B., Andreatini, R., Joca, S. & Wegener, G. (2022). The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants. Molecular Psychiatry, 27(8), 3138–3149 . https://doi.org/10.1038/s41380-022-01598-4

Kriegenburg, F., Huiting, W., van Buuren-Broek, F., Zwilling, E., Hardenberg, R., Mari, M. C., Kraft, C. & Reggiori, F. M. (2022). The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy. Autophagy Reports, 1(1), 345-367. https://doi.org/10.1080/27694127.2022.2104781

Mogensen, E. H., Poulsen, E. T., Thøgersen, I. B., Yamamoto, K., Brüel, A. & Enghild, J. J. (2022). The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea. Experimental Eye Research, 219, Article 109081. https://doi.org/10.1016/j.exer.2022.109081

van Soldt, B. J., Wang, T., Filogonio, R. & Danielsen, C. C. (2022). The mechanical and morphological properties of systemic and pulmonary arteries differ in the Madagascar ground boa, a snake without ventricular pressure separation. Journal of Experimental Biology, 225(13), Article jeb244419. https://doi.org/10.1242/jeb.244419

Reggiori, F. M., Boya, P., da Costa, D., Elazar, Z., Eskelinen, E.-L., Farrés, J., Guettler, S., Kraft, C., Jungbluth, H., Martinez, A., Morel, E., Pless, O., Proikas-Cezanne, T. & Simonsen, A. (2022). The mechanism of Macroautophagy: The movie. Autophagy Reports, 1(1), 414-417. https://doi.org/10.1080/27694127.2022.2096115

Rognant, S., Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjaer, C., Jepps, T. A. & Matchkov, V. V. (2022). The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells. Frontiers in Physiology, 13, 1007340. Article 1007340. https://doi.org/10.3389/fphys.2022.1007340

Fruergaard, M. U., Dach, I., Andersen, J. L., Ozol, M., Shasavar, A., Quistgaard, E. M. H., Poulsen, H., Fedosova, N. & Nissen, P. (2022). The Na,K-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. Journal of Biological Chemistry, 298(9), Article 102317. https://doi.org/10.1016/j.jbc.2022.102317

Laustsen, M. M., Nørgaard, M., Lam, M. Q., Koefoed-Nielsen, P. & Staunstrup, N. H. (2022). The novel HLA class I allele, HLA-B*14:110, identified by next-generation sequencing. HLA, 100(5), 520-522. https://doi.org/10.1111/tan.14721

Chernyakov, D., Fischer, A., Brandau, M., Petrillo, F., Fenton, R. A. & Edemir, B. (2022). The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression. Scientific Reports, 12(1), Article 20304. https://doi.org/10.1038/s41598-022-24237-y

Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022). The presence of interferon affects the progression of non-alcoholic fatty liver disease. Genes and Immunity, 23(5), 157–165. https://doi.org/10.1038/s41435-022-00176-6

Hennings, V., Thörn, K., Albinsson, S., Lingblom, C., Andersson, K., Andersson, C., Järbur, K., Pullerits, R., Idorn, M., Paludan, S. R., Eriksson, K. & Wennerås, C. (2022). The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from COVID-19. European Journal of Immunology, 52(5), 800-809. https://doi.org/10.1002/eji.202149655

Engbjerg, J. S., Costanzo, V., Sardella, D., Bordoni, L., Jakobsen, S., D'Apolito, L., Frøkiær, J., Trepiccione, F., Capasso, G. & Frische, S. (2022). The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo. Molecular Imaging, 2022, Article 7908357. https://doi.org/10.1155/2022/7908357

Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hørslev-Pedersen, K., Hetland, M. L., Stengaard-Pedersen, K., Østergaard, M., Ørnbjerg, L., Junker, P., Sharpe, A. H., Freeman, G. J., Hvid, M., Moestrup, S. K., Hauge, E. M. & Deleuran, B. (2022). The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings. Frontiers in Immunology, 13, Article 773946. https://doi.org/10.3389/fimmu.2022.773946

Paternoster, V., Cömert, C., Kirk, L. S., la Cour, S. H., Fryland, T., Fernandez-Guerra, P., Stougaard, M., Nyengaard, J. R., Qvist, P., Bross, P., Børglum, A. D. & Christensen, J. H. (2022). The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation. Translational Psychiatry, 12(1), Article 319. https://doi.org/10.1038/s41398-022-02053-2

Julander, J. G., Anderson, N., Haese, N., Andoh, T., Streblow, D. N., Cortez, P., Carter, K., Marniquet, X., Watson, H. & Mandron, M. (2022). Therapeutic and prophylactic treatment with a virus-specific antibody is highly effective in rodent models of Chikungunya infection and disease. Antiviral Research, 202, Article 105295. https://doi.org/10.1016/j.antiviral.2022.105295

Manry, J., Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., de Prost, N., Tandjaoui-Lambiotte, Y. ... CoV-Contact Cohort (2022). The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies. Proceedings of the National Academy of Sciences (PNAS), 119(21), Article e2200413119. https://doi.org/10.1073/pnas.2200413119

Yilmaz, Z., Larsen, J. T., Nissen, J. B., Crowley, J. J., Mattheisen, M., Bulik, C. M. & Petersen, L. V. (2022). The role of early-life family composition and parental socio-economic status as risk factors for obsessive-compulsive disorder in a Danish national cohort. Journal of Psychiatric Research, 149, 18-27. https://doi.org/10.1016/j.jpsychires.2022.02.004

Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A., Lassen, T. R., Jørgensen, M., Bæk, R., Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M. ... Drasbek, K. R. (2022). The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance. International Journal of Molecular Sciences , 23(6), Article 3334. https://doi.org/10.3390/ijms23063334

Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F. ... Nyegaard, M. (2022). The sequences of 150,119 genomes in the UK Biobank. Nature, 607, 732-740. https://doi.org/10.1038/s41586-022-04965-x

Li, C., Zhang, Y., Leng, L., Pan, X., Zhao, D., Li, X., Huang, J., Bolund, L., Lin, G., Luo, Y. & Xu, F. (2022). The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic development. Frontiers in Cell and Developmental Biology, 10, Article 1020490. https://doi.org/10.3389/fcell.2022.1020490

Boedtkjer, E. & Aalkjær, C. (2022). The solution to bicarbonate. American Journal of Physiology: Heart and Circulatory Physiology, 322(4), H685-H686. https://doi.org/10.1152/ajpheart.00057.2022

Casares, L., Moreno, R., Ali, K. X., Higgins, M., Dayalan Naidu, S., Neill, G., Cassin, L., Kiib, A. E., Svenningsen, E. B., Minassi, A., Honda, T., Poulsen, T. B., Wiel, C., Sayin, V. I., Dinkova-Kostova, A. T., Olagnier, D. & de la Vega, L. (2022). The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity. Redox Biology, 51, Article 102291. https://doi.org/10.1016/j.redox.2022.102291

Displaying results 1751 to 1800 out of 11228

Revised 21.08.2025