Peer-reviewed publikationer

Peer-reviewed publications

Bak, R. O. (2019). The Potential of CRISPR/Cas9 in Hematotherapy. Stem Cells and Development, 28(11), 710-711. https://doi.org/10.1089/scd.2019.0079

Olesen, M. S., Hauge, B., Ohrt, L., Olesen, T. N., Roskær, J., Bæk, V., Elbæk, H. O., Nøhr, B., Nyegaard, M., Overgaard, M. T., Humaidan, P., Forman, A. & Agerholm, I. (2019). Therapeutic endometrial scratching and implantation after in vitro fertilization: a multicenter randomized controlled trial. Fertility and Sterility, 112(6), 1015-1021. https://doi.org/10.1016/j.fertnstert.2019.08.010

Axelgaard, E., Jensen, T. I. & Bak, R. O. (2019). Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British Journal of Haematology, 185(5), 821-835. https://doi.org/10.1111/bjh.15851

Gonçalves, O. S. L., Christiansen, G., Holm, A., Herrmann, B., Klintstedt, M., Petersen, S. B. & Birkelund, S. (2019). The repeated 36 amino acid motif of Chlamydia trachomatis Hc2 protein binds to the major groove of DNA. Research in Microbiology, 170(6-7), 256-262. https://doi.org/10.1016/j.resmic.2019.08.002

Bjerre, H. L., Christensen, J. B., Buus, N. H., Simonsen, U. & Su, J. (2019). The role of aliskiren in the management of hypertension and major cardiovascular outcomes: a systematic review and meta-analysis. Journal of Human Hypertension, 33(11), 795-806. https://doi.org/10.1038/s41371-018-0149-8

Cedzynski, M., Thielens, N. M., Mollnes, T. E. & Vorup-Jensen, T. (red.) (2019). The role of complement in health and disease. Frontiers Media S.A. Frontiers in Immunology https://doi.org/10.3389/978-2-88963-159-9

Poulsen, E. T., Nielsen, N. S., Scavenius, C., Mogensen, E. H., Risør, M. W., Runager, K., Lukassen, M. V., Rasmussen, C. B., Christiansen, G., Richner, M., Vorum, H. & Enghild, J. J. (2019). The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation. Journal of Biological Chemistry, 294(31), 11817-11828. https://doi.org/10.1074/jbc.RA119.009050

Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi-Hemami, H., Teilum, K. & Ellgaard, L. (2019). The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework. Journal of Biological Chemistry, 294(22), 8745-8759. https://doi.org/10.1074/jbc.RA119.007491

Li, K., Neumann, K., Duhan, V., Namineni, S., Hansen, A. L., Wartewig, T., Kurgyis, Z., Holm, C. K., Heikenwalder, M., Lang, K. S. & Ruland, J. (2019). The uric acid crystal receptor Clec12A potentiates type I interferon responses. Proceedings of the National Academy of Sciences (PNAS), 116(37), 18544-18549. https://doi.org/10.1073/pnas.1821351116

Jensen, P. S., Aalkjaer, C. & Bek, T. (2019). The vasodilating effect of glucose differs among vessels at different branching level in the porcine retina ex vivo. Experimental Eye Research, 179, 150-156. https://doi.org/10.1016/j.exer.2018.11.006

Matrone, C., Iannuzzi, F. & Annunziato, L. (2019). The Y ₆₈₂ ENPTY ₆₈₇ motif of APP: Progress and insights toward a targeted therapy for Alzheimer's disease patients. Ageing Research Reviews, 52, 120-128. https://doi.org/10.1016/j.arr.2019.04.003

Maxel, T., Smidt, K., Petersen, C. C., Honoré, B., Christensen, A. K., Jeppesen, P. B., Brock, B., Rungby, J., Palmfeldt, J. & Larsen, A. (2019). The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells. Scientific Reports, 9(1), Artikel 8589. https://doi.org/10.1038/s41598-019-44954-1

Hanifa, M. A., Skott, M., Maltesen, R. G., Rasmussen, B. S., Nielsen, S., Frøkiær, J., Ring, T. & Wimmer, R. (2019). Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model. Metabolomics, 15(8), Artikel 112. https://doi.org/10.1007/s11306-019-1569-3

Pedersen, L. H. (2019). To treat or not to treat: Do not let fear decide whether to use medication during pregnancy. Acta Obstetricia et Gynecologica Scandinavica, 98(7), 821-822. https://doi.org/10.1111/aogs.13643

Ørstrup, L. H., Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, J. & Glud, A. N. (2019). Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method. Heliyon, 5(11), Artikel e02892. https://doi.org/10.1016/j.heliyon.2019.e02892, https://doi.org/10.1016/j.heliyon.2019.e02892

Musliner, K., Vilhjálmsson, B. J., Albiñana Climent, C., Krebs, M. D., Zandi, P. P., Agerbo, E., Mortensen, P. B., Werge, T., Børglum, A. & Østergaard, S. D. (2019). Towards precision medicine in psychiatric care: Using polygenic risk scores to predict outcomes in hospital-treated depression patients . S88-S88. Abstract fra World Congress of Psychiatric Genetics , Anaheim , California, USA.

Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, K. J., Pers, T. H., Khodosevich, K., Simons, B. D. & Jensen, K. B. (2019). Tracing the origin of adult intestinal stem cells. Nature, 570(7759), 107-111. https://doi.org/10.1038/s41586-019-1212-5

Lin, L. & Luo, Y. (2019). Tracking CRISPR's Footprints. I Y. Luo (red.), Methods in Molecular Biology: Methods and Protocols (s. 13-28). Springer Science+Business Media. https://doi.org/10.1007/978-1-4939-9170-9_2

Habekost, M., Jørgensen, A. L., Qvist, P. & Denham, M. (2019). Transcriptomic profiling of porcine pluripotency identifies species-specific reprogramming requirements for culturing iPSCs. Stem Cell Research, 41, Artikel 101645. https://doi.org/10.1016/j.scr.2019.101645

Delaidelli, A., Jan, A., Herms, J. & Sorensen, P. H. (2019). Translational control in brain pathologies: biological significance and therapeutic opportunities. Acta Neuropathologica, 137(4), 535-555. https://doi.org/10.1007/s00401-019-01971-8

Rasmussen, C. K., Hansen, E. S., Ernst, E. & Dueholm, M. (2019). Two- and three-dimensional transvaginal ultrasonography for diagnosis of adenomyosis of the inner myometrium. Reproductive BioMedicine Online, 38(5), 750-760. https://doi.org/10.1016/j.rbmo.2018.12.033

van Diggelen, F., Hrle, D., Apetri, M., Christiansen, G., Rammes, G., Tepper, A. & Otzen, D. E. (2019). Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation. PLoS One, 14(3), Artikel 0213663. https://doi.org/10.1371/journal.pone.0213663

Budolfsen, C., Faber, J., Grimm, D., Krüger, M., Bauer, J., Wehland, M., Infanger, M. & Magnusson, N. E. (2019). Tyrosine Kinase Inhibitor-Induced Hypertension: Role of Hypertension as a Biomarker in Cancer Treatment. Current Vascular Pharmacology, 17(6), 618-634. https://doi.org/10.2174/1570161117666190130165810

Rodríguez-Rodríguez, R., Ackermann, T. N., Plaza, J. A., Simonsen, U., Matchkov, V., Llobera, A. & Munoz-Berbel, X. (2019). Ultrasensitive photonic microsystem enabling sub-micrometric monitoring of arterial oscillations for advanced cardiovascular studies. Frontiers in Physiology, 10, Artikel 940. https://doi.org/10.3389/fphys.2019.00940

Vestergaard, E. T., Jessen, N., Møller, N. & Jørgensen, J. O. L. (2019). Unacylated Ghrelin does not Acutely Affect Substrate Metabolism or Insulin Sensitivity in Men with Type 2 Diabetes. Journal of Clinical Endocrinology and Metabolism, 104(6), 2435-2442. https://doi.org/10.1210/jc.2018-02601

Ferreira, N., Saraiva, M. J. & Almeida, M. R. (2019). Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis. International Journal of Molecular Sciences , 20(6), Artikel 1287. https://doi.org/10.3390/ijms20061287

Dollerup, O. L., Treebak, J. T. & Jessen, N. (2019). Underpowered or negative? A crucial distinction. Diabetologia, 62(6), 1094-1095. https://doi.org/10.1007/s00125-019-4853-x

Gammelgaard, K. R., Vad-Nielsen, J., Clement, M. S., Weiss, S., Daugaard, T. F., Dagnæs-Hansen, F., Meldgaard, P., Sorensen, B. S. & Nielsen, A. L. (2019). Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC. Translational Oncology, 12(3), 432-440. https://doi.org/10.1016/j.tranon.2018.11.017

Voss, N. C. S., Kold-Petersen, H. H., Henningsen, M. B., Homilius, C. & Boedtkjer, E. (2019). Upregulated Na⁺/H⁺-exchange protects human colon cancer tissue against intracellular acidification. BioMed Research International, 2019, Artikel 3702783. https://doi.org/10.1155/2019/3702783

Staehr, C., Rajanathan, R. & Matchkov, V. (2019). Upregulation of Endothelial Kir2. 1 Channel Disturbs Neurovascular Coupling in Familial Hemiplegic Migraine. Acta Physiologica (Print), 227(S721), 121-121.

Meier, M., Knudsen, A. R., Andersen, K. J., Ludvigsen, M., Eriksen, P. L., Honoré, B. & Mortensen, F. V. (2019). Upregulation of ureagenesis may be pivotal for survival of post-hepatectomy liver failure in rats. Poster-session præsenteret på 13th Congress of the European – African Hepato-Pancreato-Biliary Association, Amsterdam, Holland.

Hinrichs, G. R., Weyer, K., Friis, U. G., Svenningsen, P., Lund, I. K., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H. (2019). Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice. Acta Physiologica (Online), 227(4), Artikel e13362. https://doi.org/10.1111/apha.13362

Volqvartz, T., Vestergaard, A. L., Aagaard, S. K., Andreasen, M. F., Lesnikova, I., Uldbjerg, N., Larsen, A. & Bor, P. (2019). Use of alternative medicine, ginger and licorice among Danish pregnant women - a prospective cohort study. BMC Complementary and Alternative Medicine, 19(1), Artikel 5. https://doi.org/10.1186/s12906-018-2419-y

Gaspar, H. A., Gerring, Z., Hübel, C., Middeldorp, C. M., Derks, E. M., Breen, G. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder. Translational Psychiatry, 9(1), Artikel 117. https://doi.org/10.1038/s41398-019-0451-4

Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J. D., Fallin, M. D., Bybjerg-Grauholm, J. ... Mill, J. (2019). Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight. Philosophical Transactions of the Royal Society B: Biological Sciences, 374(1770), Artikel 20180120. https://doi.org/10.1098/rstb.2018.0120

Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A. ... Jacobsson, B. (2019). Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nature Communications, 10(1), 1-13. Artikel 3927. https://doi.org/10.1038/s41467-019-11881-8

Kjaer, L., Skov, V., Andersen, M. T., Aggerholm, A., Clair, P., Gniot, M., Soeby, K., Udby, L., Dorff, M. H., Hasselbalch, H. & Pallisgaard, N. (2019). Variant-specific discrepancy when quantitating BCR-ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay. European Journal of Haematology, 103(1), 26-34. https://doi.org/10.1111/ejh.13238

Matchkov, V. V. (2019). Vascular microdomain signalling and possible novel treatments in cardiovascular diseases. Experimental Physiology, 104(7), 1011-1012. https://doi.org/10.1113/EP087819

Giesecke, T., Himmerkus, N., Leipziger, J., Bleich, M., Koshimizu, T. A., Fähling, M., Smorodchenko, A., Shpak, J., Knappe, C., Isermann, J., Ayasse, N., Kawahara, K., Schmoranzer, J., Gimber, N., Paliege, A., Bachmann, S. & Mutig, K. (2019). Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells. Journal of the American Society of Nephrology : JASN, 30(6), 946-961. https://doi.org/10.1681/ASN.2018080816

Brix, G. S., Ovesen, T. & Devantier, L. (2019). Vestibular evoked myogenic potential in healthy adolescents. International Journal of Pediatric Otorhinolaryngology, 116, 49-57. https://doi.org/10.1016/j.ijporl.2018.10.019

Kaiser, K., Gyllborg, D., Procházka, J., Salašová, A., Kompaníková, P., Molina, F. L., Laguna-Goya, R., Radaszkiewicz, T., Harnoš, J., Procházková, M., Potěšil, D., Barker, R. A., Casado, Á. G., Zdráhal, Z., Sedláček, R., Arenas, E., Villaescusa, J. C. & Bryja, V. (2019). WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nature Communications, 10(1), Artikel 1498. https://doi.org/10.1038/s41467-019-09298-4

Johnsen, N., Hamilton, A. D. M., Greve, A. S., Christensen, M. G., Therkildsen, J. R., Wehmöller, J., Skals, M. & Praetorius, H. A. (2019). α-Haemolysin production, as a single factor, causes fulminant sepsis in a model of Escherichia coli-induced bacteraemia. Cellular Microbiology, 21(6), Artikel e13017. https://doi.org/10.1111/cmi.13017

Khammy, M. M., Kim, S., Bentzen, B. H., Lee, S., Choi, I., Aalkjær, C. & Jepps, T. A. (2018). 4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K_v7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries. British Journal of Pharmacology, 175(3), 501-516. https://doi.org/10.1111/bph.14097

Pedersen, M. A., Bouchelouche, K. & Vendelbo, M. H. (2018). 68Ga-PSMA Uptake in middle lobe syndrome. Clinical Nuclear Medicine, 43(10), e376-e377. https://doi.org/10.1097/RLU.0000000000002213

Giambartolomei, C., Liu, J. Z., Zhang, W., Hauberg, M., Shi, H., Boocock, J., Pickrell, J., Jaffe, A. E., Pasaniuc, B. & Roussos, P. (2018). A Bayesian framework for multiple trait colocalization from summary association statistics. Bioinformatics, 34(15), 2538-2545. https://doi.org/10.1093/bioinformatics/bty147

Weyer, K., Andersen, P. K., Schmidt, K., Mollet, G., Antignac, C., Birn, H., Nielsen, R. & Christensen, E. I. (2018). Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice. Kidney International, 93(2), 335-342. https://doi.org/10.1016/j.kint.2017.07.024

Mohammadnejad, A., Brasch-Andersen, C., Li, W., Haagerup, A., Baumbach, J. & Tan, Q. (2018). A case-only genome-wide association study on gene-sex interaction in allergic rhinitis. Annals of Allergy, Asthma & Immunology, 121(3), 366-367.e2. https://doi.org/10.1016/j.anai.2018.07.001

Boedtkjer, E. (2018). Acid-base regulation and sensing: accelerators and brakes in metabolic regulation of cerebrovascular tone. Journal of Cerebral Blood Flow and Metabolism, 38(4), 588-602. https://doi.org/10.1177/0271678X17733868

Jordan, V. E., Walker, J. A., Beckstrom, T. O., Steely, C. J., McDaniel, C. L., St Romain, C. P., The Baboon Genome Analysis Consortium, Worley, K. C., Phillips-Conroy, J., Jolly, C. J., Rogers, J., Konkel, M. K. & Batzer, M. A. (2018). A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. Mobile DNA, 9(1), Artikel 13. https://doi.org/10.1186/s13100-018-0118-3

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework. BMC Genomics, 19(1), Artikel 494. https://doi.org/10.1186/s12864-018-4859-7

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Revideret 21.08.2025