Peer-reviewed publikationer

Peer-reviewed publications

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Nitulescu, A. M., Du, W., Glaser, V., Kath, J., Aird, E. J., Cullot, G., Greensmith, R., Mikkelsen, N. S., Stein, M., Bak, R. O., Kaminski, M., Corn, J. E. & Wagner, D. L. (2025). Single-stranded HDR templates with truncated Cas12a-binding sequences improve knock-in efficiencies in primary human T cells. Molecular Therapy Nucleic Acids, 36(2), Artikel 102568. https://doi.org/10.1016/j.omtn.2025.102568

Nissen Pedersen, A. K., Gormsen, L. C., Nielsen, S., Jessen, N. & Bjerre, M. (2024). Metformin Improves the Prerequisites for FGF21 Signaling in Patients with Type 2 Diabetes. The Journal of clinical endocrinology and metabolism, 109(2), e552-e561. https://doi.org/10.1210/clinem/dgad583

Nissen, P., Jensen, A.-M. L., Møller, J. V., Christensen, S. B., Søhoel, H., Olsen, C. E., Denmeade, S. R. & Isaacs, J. T. (2006). Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells. Bioorganic & Medicinal Chemistry, 14(8), 2810-2815.

Nissen, K. K., Vogel, U. & Nexø, B. A. (2009). Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines. Anti-Cancer Drugs, 20(3), 174-178.

Nissen, K. K., Laska, M. J., Hansen, B., Pedersen, F. S. & Nexø, B. A. (2012). No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients. Virology Journal, 9(188), 1-4. https://doi.org/10.1186/1743-422X-9-188

Nissen, K. K., Laska, M. J., Hansen, B., Terkelsen, T., Villesen, P., Bahrami, S., Petersen, T., Pedersen, F. S. & Nexø, B. A. (2013). Endogenous retroviruses and multiple sclerosis-new pieces to the puzzle. B M C Neurology, 13(111), 1-5. https://doi.org/10.1186/1471-2377-13-111

Nissen, S. K., Højen, J. F., Andersen, K. L. D., Kofod-Olsen, E., Berg, R. K., Paludan, S. R., Ostergaard, L., Jakobsen, M. R., Tolstrup, M. & Mogensen, T. H. (2014). Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates to chronic immune activation. Clinical and Experimental Immunology, 177(1), 295-309. https://doi.org/10.1111/cei.12317

Nissen, L., Winther, S., Isaksen, C., Ejlersen, J. A., Brix, L., Urbonaviciene, G., Frost, L., Helleskov Madsen, L., Lyhne Knudsen, L., Schmidt, S. E., Holm, N. R., Maeng, M., Nyegaard, M., Bøtker, H. E. & Bøttcher, M. (2016). Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD): Study protocol for a randomised controlled trial. Trials, 17(1), Artikel 262. https://doi.org/10.1186/s13063-016-1388-z

Nissen, J. B., Søholm Hansen, C., Starnawska, A., Mattheisen, M., Børglum, A., Buttenschøn, H. N. & Hollegård, M. (2016). DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Frontiers in Psychiatry, 7(35), Artikel 35. https://doi.org/10.3389/fpsyt.2016.00035

Nissen, S. K., Pedersen, J. G., Helleberg, M., Kjaer, K., Thavachelvam, K., Obel, N., Tolstrup, M., Jakobsen, M. R. & Mogensen, T. H. (2018). Multiple Homozygous Variants in the STING-Encoding TMEM173 Gene in HIV Long-Term Nonprogressors. Journal of Immunology, 200(10), 3372-3382. https://doi.org/10.4049/jimmunol.1701284

Nissen, S. K., Laursen, A. L., Poulsen, L. H. & Mogensen, T. H. (2018). Identification of a novel mutation in the factor VIII gene causing severe haemophilia A. BMC Hematology, 18(1), 17. Artikel 17. https://doi.org/10.1186/s12878-018-0113-4

Nissen, S. K., Christiansen, M., Helleberg, M., Kjær, K., Jørgensen, S. E., Gerstoft, J., Katzenstein, T. L., Benfield, T., Kronborg, G., Larsen, C. S., Laursen, A., Pedersen, G., Jakobsen, M. R., Tolstrup, M. & Mogensen, T. H. (2018). Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules. Scientific Reports, 8(1), 15253. Artikel 15253. https://doi.org/10.1038/s41598-018-33481-0

Nissen, S. K., Shrivastava, K., Schulte, C., Otzen, D. E., Goldeck, D., Berg, D., Møller, H. J., Maetzler, W. & Romero-Ramos, M. (2019). Alterations in Blood Monocyte Functions in Parkinson's Disease. Movement Disorders, 34(11), 1711-1721. https://doi.org/10.1002/mds.27815

Nissen, S. K., Ferreira, S. A., Nielsen, M. C., Schulte, C., Shrivastava, K., Hennig, D., Etzerodt, A., Graversen, J. H., Berg, D., Maetzler, W., Panhelainen, A., Møller, H. J., Brockmann, K. & Romero-Ramos, M. (2021). Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease. Movement Disorders, 36(4), 963-976. https://doi.org/10.1002/mds.28424

Nissen, P., Jensen, A. M. L., Marchand, A., Olesen, C., Holm, P., Picard, M., Vilsen, B., Jaxel, C., Champeil, P., Andersen, J. P., LE MAIRE, M. & Møller, J. V. (2006). The structure and function of the sarcoplasmic reticulum Ca ²⁺-ATPase. Acta Biomedica de l'Ateneo Parmense, 77(SUPPL. 3), 25-26.

Ning, G., Maunsbach, A. B. & Esmann, M. (1993). Ultrastructure of membrane-bound Na, K-ATPase after extensive tryptic digestion. FEBS Letters, 330(1), 19-22.

Nilsson, S. K., Klinger, S. C., Raarup, M. K., Ryan, R., Nielsen, M. S. & Olivecrona, G. (2008). Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. Journal of Cell Science.

Nilsson, M., Gjedde, A., Brock, B., Gejl, M. & Rungby, J. (2018). The effects of incretin hormones on cerebral glucose metabolism in health and disease. Neuropharmacology, 136(Pt B), 243-250. https://doi.org/10.1016/j.neuropharm.2017.12.031

Nikolajsen, G., Jensen, M. S. & West, M. J. (2011). Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model. Neurobiology of Aging, 32(11), 1927-1931.

Nikolajsen, G. N., Jensen, M. S. & West, M. J. (2016). A zinc fixative for 3D visualization of cerebral capillaries and pericytes. Journal of Neuroscience Methods, 257, 1-6. https://doi.org/10.1016/j.jneumeth.2015.09.016

Nikolajsen, G. N., Kotynski, K. A., Jensen, M. S. & West, M. J. (2015). Quantitative analysis of the capillary network of aged APPswe/PS1dE9 transgenic mice. Neurobiology of Aging, 36(11), 2954-62. https://doi.org/10.1016/j.neurobiolaging.2015.08.004

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M. ... Koenen, K. C. (2019). International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications, 10(1), Artikel 4558. https://doi.org/10.1038/s41467-019-12576-w

Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babić, D., Bacanu, S.-A., Baker, D. G. ... AURORA Study (2024). Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nature Genetics, 56(5), 792-808. https://doi.org/10.1038/s41588-024-01707-9

Nieto-Gonzalez, J. L., Moser, J. M., Lauritzen, M., Schmitt-John, T. & Jensen, K. (2011). Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS. Cerebral Cortex, 21, 625-635.

Nieto-Gonzalez, J. L. & Jensen, K. (2013). BDNF Depresses Excitability of Parvalbumin-Positive Interneurons through an M-Like Current in Rat Dentate Gyrus. PLoS One, 8(6), e67318. https://doi.org/10.1371/journal.pone.0067318

Nieto-Gonzalez, J. L., Holm, M. M., Vardya, I., Christensen, T., Wiborg, O. & Jensen, K. (2015). Presynaptic Plasticity as a Hallmark of Rat Stress Susceptibility and Antidepressant Response. PLoS One, 10(3).

Niemann, C. U., Åbrink, M., Pejler, G., Fischer, R. L., Christensen, E. I., Knight, S. D. & Borregaard, N. (2007). Neutrophil Elastase depends on Serglycin Proteoglycan for Localization in Granules. Blood, 109, 4478-4486.

Niemann, I., Sunde, L. & Petersen, L. K. (2007). Evaluation of the risk of persistent trophoblastic disease after twin pregnancy with diploid hydatidiform mole and coexisting normal fetus. Am. J. Obstet. Gynecol., 197(1), 45.

Niemann, I., Hansen, E. S. & Sunde, L. (2007). The risk of persistent trophoblastic disease after hydatidiform mole classified by morphology and ploidy. Gynecologic Oncology, 104(2), 411-5. https://doi.org/10.1016/j.ygyno.2006.08.025

Niemann, I., Bolund, L. & Sunde, L. (2008). Twin pregnancies with diploid hydatidiform mole and co-existing normal fetus may originate from one oocyte. Human Reproduction, 23(9), 2031-5. https://doi.org/10.1093/humrep/den226

Niemann, I., Petersen, L. K., Hansen, E. S. & Sunde, L. (2006). Predictors of low risk of persistent trophoblastic disease in molar pregnancies. Obstetrics and Gynecology, 107(5), 1006-11. https://doi.org/10.1097/01.AOG.0000210635.24543.3b

Niemann, I., Petersen, L. K., Hansen, ES. & Sunde, L. (2007). Differences in current clinical features of diploid and triploid hydatidiform mole. B J O G, 114(10), 1273-7. https://doi.org/10.1111/j.1471-0528.2007.01449.x

Nielsen(Holm), M. M., Krogsgaard-Larsen, P., Liljefors, T. & Egebjerg, J. (2003). The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741. Molecular Pharmacology, 63, 19-25.

Nielsen, M. F., Caumo, A., Aagaard, N. K., Chandramouli, V., Schumann, W. C., Landau, B. R., O., S. & Vilstrup, H. (2005). Contribution of defects in glucose uptake to carbohydrate intolerance in liver cirrhosis: Assessment during physiologic glucose and insulin concentrations. Am. J. Physiol. Gastrointest. Liver Physiol., 288, G1135-43.

Nielsen, G., Malmendal, A., Meissner, A., Møller, J. V. & Nielsen, N. C. (2003). NMR studies of the fifth transmembrane segment of sarcoplasmic reticulum Ca²⁺-ATPase reveals a hinge close to the Ca²⁺-ligating residues. FEBS Letters, 544, 50-56.

Nielsen, L. P. & Madsen, F. F. (2005). Farmakoterapi ved allergisk sygdom. Ugeskrift for Læger, 167(6), 661-663.

Nielsen, L. P., Mygind, N. & Dahl, R. (2001). Intranasal corticosteroids for allergic rhinitis: superior relief? Drugs, 61, 1563-1579.

Nielsen, O. B. & Clausen, T. (2000). The Na⁺,K⁺-pump protects muscle excitability and contractility during exercise. Exercise and Sport Sciences Reviews, 28, 159-164.

Nielsen, O. B., Paoli, F. D. & Overgaard, K. (2001). Protective effects of lactic acid on force production in rat skeletal muscle. Journal of Physiology, 536, 161-166.

Nielsen, O. B., Ørtenblad, N., Lamb, G. D. & Stephenson, D. G. (2004). Excitability of the T-tubular system in rat skeletal muscle: roles K⁺ and Na⁺ gradients and Na⁺ -K⁺ pump activity. Journal of Physiology, 557, 133-146.

Nielsen, A. L., Jørgensen, P. & Jørgensen, A. L. (2002). Mutations associated with a childhood leukodystrophy, Alexander disease, cause deficiency in dimerization of the cytoskeletal protein GFAP. Journal of Neurogenetics, 16(3), 175-179.

Nielsen, A. L., Jørgensen, P., Lerouge, T., Cerviño, M., Chambon, P. & Losson, R. (2004). Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif. Molecular and Cellular Biology, 24(12), 5184-5196. https://doi.org/10.1128/MCB.24.12.5184-5196.2004

Nielsen, A. L., Holm, I. E., Johansen, M., Bonven, B., Jørgensen, P. & Jørgensen, A. L. (2002). A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins. Journal of Biological Chemistry, 277(33), 29983-29991. https://doi.org/10.1074/jbc.M112121200

Nielsen, M. F., Caumo, A., Chandramouli, V., Schumann, W. C., Cobelli, C., Landau, B. R., Vilstrup, H., Rizza, R. A. & Schmitz, O. (2004). Impaired basal glucose effectiveness but unaltered fasting glucose release and gluconeogenesis during short-term hypercortisolemia in healthy subjects. Am. J. Physiol. Endocrinol. Metab., 286, 102-110.

Nielsen, B. D. & Frøbert, O. (2005). Single coronary artery, ventricular tachycardia, and a family history of sudden death. Cardiol Rev, 13(5), 263-265.

Nielsen, R. C., Sørensen, T. L., Møller, J. V., Nissen, P., Jidenko, M., le Maire, M. & Jaxel, C. (2005). Crystallization of a mammalian membrane protein overexpressed in S. cerevisiae. Proceedings of the National Academy of Sciences (PNAS), 102(11687-1191).

Nielsen, J., Kwon, T.-H., Frøkiær, J., Knepper, M. A. & Nielsen, S. (2007). Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade. American Journal of Physiology: Renal Physiology, 1(292), F382-394.

Nielsen, J., Kwon, TH., Frøkiær, J., Knepper, M. A. & Nielsen, S. (2006). Lithium-induced NDI in rats associated with loss of αENaC regulation by aldosterone in CCD. American Journal of Physiology: Renal Physiology, 290(5), 1222-1233.

Nielsen, J., Kwon, T.-H., Prætorius, J., Frøkiær, J., Knepper, M. A. & Nielsen, S. (2006). Aldosterone increases urine production and decreases apical AQP2 expression in rats with diabetes insipidus. American Journal of Physiology: Renal Physiology, 290(2), F438-49.

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Revideret 21.08.2025