Institut for Biomedicin - Medarbejderportal

Peer-reviewed publikationer

Peer-reviewed publications

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Henriksen, J., Andersen, C. U., Donskov, F., Hoffmann-Lücke, E., Greibe, E. & Fristrup, N. (2025). Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKI) for optimized outcome in patients with metastatic renal cell carcinoma. The TKI-TDM Trial. Study protocol. Acta Oncologica, 64, 729-733. https://doi.org/10.2340/1651-226X.2025.43693

Julander, J. G., Anderson, N., Haese, N., Andoh, T., Streblow, D. N., Cortez, P., Carter, K., Marniquet, X., Watson, H. & Mandron, M. (2022). Therapeutic and prophylactic treatment with a virus-specific antibody is highly effective in rodent models of Chikungunya infection and disease. Antiviral Research, 202, Artikel 105295. https://doi.org/10.1016/j.antiviral.2022.105295

Yang, C., Gao, S., Song, P., Dagnæs-Hansen, F., Jakobsen, M. V. & Kjems, J. (2018). Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. A C S Applied Materials and Interfaces, 10(23), 19494–19503. https://doi.org/10.1021/acsami.8b05513

Christiansen, S. H., Zhang, X., Juul-Madsen, K., Hvam, M. L., Vad, B. S., Behrens, M. A., Thygesen, I. L., Jalilian, B., Pedersen, J. S., Howard, K., Otzen, D. E. & Vorup-Jensen, T. (2017). The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage. B B A - Biomembranes, 1859(3), 425-437. https://doi.org/10.1016/j.bbamem.2017.01.001

Thomsen, J. S., Andreasen, C. M., Bakalova, L. P., Brüel, A., Hauge, E. M., Eschen, G. E. T., Kiil, B. J., Delaisse, J.-M., Kersh, M. E. & Levin Andersen, T. (2016). The radial distribution of the intracortical porosity within the fibula diaphysis. Poster-session præsenteret på Annual meating American Society of Bone and Mineral Research, Atlanta, Georgia, USA.

Soerensen, A. L., Nielsen, L. P., Poulsen, B. K., Lisby, M. & Mainz, J. (2014). The Quality of Prescribing for Psychiatric Patients. Value in Health, 17(7), A455. https://doi.org/10.1016/j.jval.2014.08.1246

Paternoster, V., Cömert, C., Kirk, L. S., la Cour, S. H., Fryland, T., Fernandez-Guerra, P., Stougaard, M., Nyengaard, J. R., Qvist, P., Bross, P., Børglum, A. D. & Christensen, J. H. (2022). The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation. Translational Psychiatry, 12(1), Artikel 319. https://doi.org/10.1038/s41398-022-02053-2

Braun, F., Rinschen, M., Buchner, D., Bohl, K., Plagmann, I., Bachurski, D., Richard Späth, M., Antczak, P., Göbel, H., Klein, C., Lackmann, J.-W., Kretz, O., Puelles, V. G., Wahba, R., Hallek, M., Schermer, B., Benzing, T., Huber, T. B., Beyer, A. ... Müller, R.-U. (2020). The proteomic landscape of small urinary extracellular vesicles during kidney transplantation. Journal of Extracellular Vesicles, 10(1), Artikel e12026. https://doi.org/10.1002/jev2.12026

Lindegaard Pedersen, M., Krüger, M., Grimm, D., Infanger, M. & Wehland, M. (2020). The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension. Basic & Clinical Pharmacology & Toxicology, 126(1), 32-42. https://doi.org/10.1111/bcpt.13305

Carlo, A.-S., Gustafsen, C., Mastrobuoni, G., Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M., Nykjaer, A., Herz, J., Heeren, J., Kempa, S., Petersen, C. M. & Willnow, T. E. (2013). The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain. Journal of Neuroscience, 33(1), 358-70. https://doi.org/10.1523/JNEUROSCI.2425-12.2013

Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hørslev-Pedersen, K., Hetland, M. L., Stengaard-Pedersen, K., Østergaard, M., Ørnbjerg, L., Junker, P., Sharpe, A. H., Freeman, G. J., Hvid, M., Moestrup, S. K., Hauge, E. M. & Deleuran, B. (2022). The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings. Frontiers in Immunology, 13, Artikel 773946. https://doi.org/10.3389/fimmu.2022.773946

Duus Holle, S. L., Søholm, H., Møller, J. E., Winther-Jensen, M., Kunkel, J. B., Okkels Jensen, L., Kjærgaard, J., Lindholm, M. G., Helgestad, O. K. L., Wiberg, S., Sousa, R. R., Holmvang, L., Thomsen, J. H., Goetze, J. P., Hassager, C. & Frydland, M. (2025). The prognostic value of neurohormonal and inflammatory biomarkers in addition to the TIMI risk score in patients with ST-elevation myocardial infarction. Biomarkers, 30(1), 1-9. https://doi.org/10.1080/1354750X.2024.2435866

Korsgaard, U., Kristensen, M. P., García-Rodríguez, J. L., Kjær-Frifeldt, S., Lindebjerg, J., Hansen, T. F., Kjems, J., Hager, H. & Kristensen, L. S. (2025). The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population-based cohort study. International Journal of Cancer. Advance online publication. https://doi.org/10.1002/ijc.35507, https://doi.org/10.1002/ijc.35507

Jakobsen, T., Pløen, G. G., Behsen, A. D., Møller, H. J., Plesner, T., Dybkær, K., Andersen, M. N., Misund, K. & Kristensen, L. S. (2024). The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells. Journal of Cellular and Molecular Medicine, 28(22), Artikel e70215. https://doi.org/10.1111/jcmm.70215

Kjær-Frifeldt, S., Hansen, T. F., Nielsen, B. S., Lindebjerg, J., Christensen, R. D., Sørensen, F. B. & Jakobsen, A. (2012). The prognostic importance of miRNA-21 in stage II colon cancer. A population based study.

Glerup, S., Kløverpris, S. & Oxvig, C. (2006). The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region. Journal of Biological Chemistry, 281(42), 31509-31516. https://doi.org/10.1074/jbc.M605824200

Degn, S. E., Jensenius, J. C. & Thiel, S. (2014). The pro-factor D cleaving activity of MASP-1/-3 is not required for alternative pathway function. Journal of Immunology, 192(12), 5447-8. https://doi.org/10.4049/jimmunol.1400777

Conticello, S. G., Kowalsman, N. D., Jacobsen, C., Yudkovsky, G., Sato, K., Elazar, Z., Pedersen, J. C. M., Aronheim, A. & Fainzilber, M. (2003). The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors. Journal of Biological Chemistry, (278), 26311-26314.

Fejerskov, O. & Larsen, M. J. (2025). The Process of de- and remineralization - the Key to Understanding Clinical Manifestations of Dental Caries. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 181-197). Wiley-Blackwell.

Engbjerg, J. S., Costanzo, V., Sardella, D., Bordoni, L., Jakobsen, S., D'Apolito, L., Frøkiær, J., Trepiccione, F., Capasso, G. & Frische, S. (2022). The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo. Molecular Imaging, 2022, Artikel 7908357. https://doi.org/10.1155/2022/7908357

Jan, A., Gonçalves, N. P., Vaegter, C. B., Jensen, P. H. & Ferreira, N. (2021). The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease: Update on Models and Hypotheses. International Journal of Molecular Sciences , 22(15), Artikel 8338. https://doi.org/10.3390/ijms22158338

Prætorius, H. (2015). The primary cilium as sensor of fluid flow: new building blocks to the model: A review in the theme: cell signaling: proteins, pathways and mechanisms. American Journal of Physiology: Cell Physiology, 308, C198.

Hennings, V., Thörn, K., Albinsson, S., Lingblom, C., Andersson, K., Andersson, C., Järbur, K., Pullerits, R., Idorn, M., Paludan, S. R., Eriksson, K. & Wennerås, C. (2022). The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from COVID-19. European Journal of Immunology, 52(5), 800-809. https://doi.org/10.1002/eji.202149655

Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022). The presence of interferon affects the progression of non-alcoholic fatty liver disease. Genes and Immunity, 23(5), 157–165. https://doi.org/10.1038/s41435-022-00176-6

Hansen, T. F., Sørensen, F. B. & Lindebjerg, J. (2011). The predictive value of miRNA in relation to first line capecitabine and oxaliplatin in patients with metastatic colorectal cancer.

West, M. J. (2012). The precision of estimates in stereological analyses. Cold Spring Harbor Protocols, 2012(9), 937-49. https://doi.org/10.1101/pdb.top071050

Matrone, C. & Brattico, E. (2015). The Power of music on Alzheimer ’s Disease and the need to understand the underlying molecular mechanisms. Journal of Alzheimer's disease and parkinsonism, 5(3). https://doi.org/10.4172/2161-0460.1000196

Lin, X., Stenvang, J., Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N. (2015). The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer. B M C Genomics, 16, 404. https://doi.org/10.1186/s12864-015-1552-y

Aliakbari, F., Mohammad-Beigi, H., Rezaei-Ghaleh, N., Becker, S., Dehghani Esmatabad, F., Eslampanah Seyedi, H. A., Bardania, H., Tayaranian Marvian, A., Collingwood, J. F., Christiansen, G., Zweckstetter, M., Otzen, D. E. & Morshedi, D. (2018). The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale, 10(19), 9174-9185. https://doi.org/10.1039/c8nr00632f

Bak, R. O. (2019). The Potential of CRISPR/Cas9 in Hematotherapy. Stem Cells and Development, 28(11), 710-711. https://doi.org/10.1089/scd.2019.0079

Ovesen, J., Møller-Madsen, B., Thomsen, J. S., Danscher, G. & Mosekilde, L. (2001). The positive effects of zinc on skeletal strength in growing rats. Bone, 29(6), 565-70. https://doi.org/10.1016/S8756-3282(01)00616-0

Chapeton-Montes, D., Plourde, L., Bouchier, C., Ma, L., Diancourt, L., Criscuolo, A., Popoff, M. R. & Brüggemann, H. (2019). The population structure of Clostridium tetani deduced from its pan-genome. Scientific Reports, 9(1), Artikel 11220. https://doi.org/10.1038/s41598-019-47551-4

Borgbo, T., Chrudimska, J., Macek, M., Jeppesen, J. V., Bøtkjær, J. A., Kristensen, S. G., Macklon, K. T., Ernst, E., Hansen, L. L. & Yding Andersen, C. (2018). The polymorphic insertion of the luteinizing hormone receptor "insLQ" show a negative association to LHR gene expression and to the follicular fluid hormonal profile in human small antral follicles. Molecular and Cellular Endocrinology, 460, 57-62. https://doi.org/10.1016/j.mce.2017.07.002

Arnou, B. J.-P., Montigny, C., Morth, J. P., Nissen, P., Jaxel, C., Møller, J. V. & le Maire, M. (2011). The Plasmodium falsiparum Ca(2+)-ATPase PfATP6: insensitive to artemisin, but a potential drug target. Biochemical Society. Transactions, 39(3), 823-831.

Arnou, B., Montigny, C., Morth, J. P., Nissen, P., Jaxel, C., Møller, J. V. & Maire, M. L. (2011). The Plasmodium falciparum Ca(2+)-ATPase PfATP6: insensitive to artemisinin, but a potential drug target. Biochemical Society. Transactions, 39(3), 823-31. https://doi.org/10.1042/BST0390823

Graversen, N. J. H., Lorentsen, R., Christian, C., Moestrup, S. K., Sigurskjold, B., Thøgersen, H. C. & Etzerodt, M. (1998). The plasminogen binding site of the C-type lectin tetranectin is located in the carbohydrate recognition domain, and binding is sensitive to both calcium and lysine. Journal of Biological Chemistry, 273(44), 29241-29246.

Christensen, E. I. (1982). The plasma membrane and cellular handling of proteins. Tokai Journal of Experimental and Clinical Medicine, 7 Suppl, 79-84.

Amoushahi, M., Sunde, L. & Lykke-Hartmann, K. (2019). The pivotal roles of the NOD-like receptors with a PYD domain, NLRPs, in oocytes and early embryo development. Biology of Reproduction, 101(2), 284-296. https://doi.org/10.1093/biolre/ioz098

Kovacs, E. J., B., B., Silber, I. E. & Neuman, J. E. (1990). The Physiological and Pathological Effects of Cytokines: LAK cell expression of PDGF and TGF beta mRNAs. John Wiley & Sons Inc.

van der Lubbe, N., Jansen, P. M., Salih, M., Fenton, R. A., van den Meiracker, A. H., Danser, A. H. J., Zietse, R. & Hoorn, E. J. (2012). The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism. Hypertension, 60(3), 741-8. https://doi.org/10.1161/HYPERTENSIONAHA.112.198135

Carlantoni, C., Liekfeld, L. M. H., Hemkemeyer, S. A., Schreier, D., Saygi, C., Kurelic, R., Cardarelli, S., Kalucka, J., Schulte, C., Beerens, M., Mailer, R. K., Schäffer, T. E., Naro, F., Pellegrini, M., Nikolaev, V. O., Renné, T. & Frye, M. (2024). The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Developmental Cell, 59(3), 308-325. https://doi.org/10.1016/j.devcel.2023.12.002

Reimers, J., Wogensen, L. D., Welinder, B., Hejnaes, K. R., Poulsen, S. S., Nilsson, P. & Nerup, J. (1991). The pharmacokinetics, distribution and degradation of human recombinant interleukin 1 beta in normal rats. Scandinavian Journal of Immunology, 34(5), 597-610.

Østergaard, J. A., Jansson Sigfrids, F., Forsblom, C., Dahlström, E. H., Thorn, L. M., Harjutsalo, V., Flyvbjerg, A., Thiel, S., Hansen, T. K. & Groop, P.-H. (2021). The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes. Scientific Reports, 11(1), 8919. Artikel 8919. https://doi.org/10.1038/s41598-021-88352-y

Ingels, C., Vanhorebeek, I., Derese, I., Jensen, L., Wouters, P. J., Thiel, S. & Van den Berghe, G. (2016). The pattern recognition molecule collectin-L1 in critically ill children. Pediatric Research, 80(2), 237-43. https://doi.org/10.1038/pr.2016.76

Schneider, G., Dobrindt, U., Brüggemann, H., Nagy, G., Janke, B., Blum-Oehler, G., Buchrieser, C., Gottschalk, G., Emödy, L. & Hacker, J. (2004). The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536. Infection and Immunity, 72(10), 5993-6001. https://doi.org/10.1128/IAI.72.10.5993-6001.2004

Joergensen, M. W., Labouriau, R., Hindkjaer, J., Stougaard, M., Kolevraa, S., Bolund, L., Agerholm, I. E. & Sunde, L. (2015). The parental origin correlates with the karyotype of human embryos developing from tripronuclear zygotes. Clinical and Experimental Reproductive Medicine, 42(1), 14-21. https://doi.org/10.5653/cerm.2015.42.1.14

Marques, J., Anwar, J., Eskildsen-Larsen, S., Rebouillat, D., Paludan, S. R., Sen, G., Williams, B. R. G. & Hartmann, R. (2008). The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain. Journal of General Virology, 89(Pt 11), 2767-72. https://doi.org/10.1099/vir.0.2008/003558-0

Dorset, S. R. & Bak, R. O. (2023). The p53 challenge of hematopoietic stem cell gene editing. Molecular Therapy Methods and Clinical Development, 30, 83-89. https://doi.org/10.1016/j.omtm.2023.06.003

Otkjaer, K., Holtmann, H., Kragstrup, T. W., Paludan, S. R., Johansen, C., Gaestel, M., Kragballe, K. & Iversen, L. (2010). The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA. P L o S One, 5(1), e8671. https://doi.org/10.1371/journal.pone.0008671

Elsner, J. S. H., Carlsson, M., Stougaard, J. K., Nygaard, U., Buchner, M., Fölster-Holst, R., Hvid, M., Vestergaard, C., Deleuran, M. & Deleuran, B. (2020). The OX40 axis is associated with both systemic and local involvement in atopic dermatitis. Acta Dermato-Venereologica, 100(6), Artikel adv00099 . https://doi.org/10.2340/00015555-3452

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Revideret 14.09.2020