Peer-reviewed publikationer

Peer-reviewed publications

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Hjelholt, A., Deleuran, B. W., Christiansen, G. & Birkelund, S. (2010). The immunoglobulin subclasses produced in response to chlamydia trachomatis in infertile women. I Schachter et al. (red.), 12th International symposium on Human Chlamydia Infections (s. 177-80)

de Vries, N. L., Swets, M., Vahrmeijer, A. L., Hokland, M. & Kuppen, P. J. K. (2016). The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment. International Journal of Molecular Sciences , 17(7). https://doi.org/10.3390/ijms17071030

Roodveldt, C., Bernardino, L., Oztop-Cakmak, O., Dragic, M., Fladmark, K. E., Ertan, S., Aktas, B., Pita, C., Ciglar, L., Garraux, G., Williams-Gray, C., Pacheco, R. & Romero-Ramos, M. (2024). The immune system in Parkinson's disease: what we know so far. Brain, 147(10), 3306-3324. https://doi.org/10.1093/brain/awae177

Brøchner, A. C., Mikkelsen, S., Hegelund, I., Hokland, M., Mogensen, O. & Toft, P. (2016). The immune response is affected for at least three weeks after extensive surgery for ovarian cancer. Danish Medical Journal, 63(6), 1-5. Artikel A5243. http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2016/DMJ_2016_06/A5243

Hørsdal, O. K., Frederiksen, P. H., Helgestad, O. K. L., Ravn, H. B., Møller, J. E., Wiggers, H., Nielsen, R. R., Gopalasingam, N. & Berg-Hansen, K. (2025). The Immediate Cardiovascular and Mitochondrial Response in Ischemic Cardiogenic Shock. Journal of Cardiovascular Translational Research, 18(5), 1204-1217. https://doi.org/10.1007/s12265-025-10647-6

Kragstrup, T. W., Heftdal, L. D., Andersen, T., Hvid, M., Gerwien, J., Sivakumar, P., Taylor, P. C., Senolt, L. & Deleuran, B. (2018). The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis. Frontiers in Immunology, 9(SEP), Artikel 2226. https://doi.org/10.3389/fimmu.2018.02226

Zhou, H., Møhlenberg, M., Terczyńska-Dyla, E., Winther, K. G., Hansen, N. H., Vad-Nielsen, J., Laloli, L., Dijkman, R., Nielsen, A. L., Gad, H. H. & Hartmann, R. (2020). The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation. Journal of Virology, 94(5), e01535-19. Artikel e01535-19. https://doi.org/10.1128/JVI.01535-19

Bieghs, L., Lub, S., Fostier, K., Maes, K., Van Valckenborgh, E., Menu, E., Johnsen, H. E., Overgaard, M. T., Larsson, O., Axelson, M., Nyegaard, M., Schots, R., Jernberg-Wiklund, H., Vanderkerken, K. & De Bruyne, E. (2014). The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic. OncoTarget, 5(22), 11193-11208. https://doi.org/10.18632/oncotarget.1933

Wacker, SJ., Aponte-Santamaria, C., Kjellbom, P., Nielsen, S., de Groot, BL. & Rützler, M. (2013). The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site. Molecular Membrane Biology, 30(3), 246-260.

Andersen, J. L., Lindberg, S., Langgård, M., Maltas, P. J., Rønn, L. C. B., Bundgaard, C., Strandbygaard, D., Thirup, S. & Watson, S. P. (2017). The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin. Bioorganic & Medicinal Chemistry Letters, 27(11), 2629-2633. https://doi.org/10.1016/j.bmcl.2017.02.028

Fröbert, O., Cajander, S. & Udell, J. A. (2023). The ideal vaccine to prevent cardiovascular disease. European Heart Journal, 44(7), 621-623. https://doi.org/10.1093/eurheartj/ehac826

Gustafsen, C., Kjolby, M., Nyegaard, M., Mattheisen, M., Lundhede, J., Buttenschøn, H., Mors, O., Bentzon, J. F., Madsen, P., Nykjaer, A. & Glerup, S. (2014). The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion. Cell Metabolism, 19(2), 310-8. https://doi.org/10.1016/j.cmet.2013.12.006

Aroankins, T. S., Murali, S. K., Fenton, R. A. & Wu, Q. (2021). The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells. Frontiers in Molecular Biosciences, 8, Artikel 790606. https://doi.org/10.3389/fmolb.2021.790606

Larsen, B., Birkelund, S., Mordhorst, CH., Ejstrup, L., Andersen, LS. & Christiansen, G. (1994). The humoral immune response to Chlamydia trachomatis in patients with acute reactive arthritis. Rheumatology, 33, 534-40.

Telinius, N., Baandrup, U., Rumessen, J. J., Pilegaard, H., Hjortdal, V. E., Aalkjaer, C. & Boedtkjer, D. M. B. (2013). The human thoracic duct is functionally innervated by adrenergic nerves. A J P: Heart and Circulatory Physiology (Online), 306(2), H206-13. https://doi.org/10.1152/ajpheart.00517.2013

Mikkelsen, J. H., Runager, K. & Andersen, C. B. F. (2020). The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus. Journal of Biological Chemistry, 295(7), 1781-1791. https://doi.org/10.1074/jbc.RA119.011612

Hess, A. P., Talbi, S., Hamilton, A. E., Baston-Buest, D. M., Nyegaard, M., Irwin, J. C., Barragan, F., Kruessel, J. S., Germeyer, A. & Giudice, L. C. (2013). The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit. RBM Online, 27(4), 423-35. https://doi.org/10.1016/j.rbmo.2013.06.013

Bernth Jensen, J. M., Skeldal, S., Petersen, M. S., Møller, B. K., Hoffmann, S., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2021). The human natural anti-αGal antibody targets common pathogens by broad-spectrum polyreactivity. Immunology, 162(4), 434-451. https://doi.org/10.1111/imm.13297

Kruse, T. A., Bolund, L., Grzeschik, K. H., Ropers, H. H., Sjöström, H., Norén, O., Mantei, N. & Semenza, G. (1988). The human lactase-phlorizin hydrolase gene is located on chromosome 2. FEBS Letters, 240(1-2), 123-126. https://doi.org/10.1016/0014-5793(88)80352-1

Celis, J. E., Rasmussen, H. H., Olsen, E., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., Gromov, P., Vorum, H. & Vassilev, A. (1994). The human keratinocyte two-dimensional protein database (update 1994): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases. Electrophoresis, 15(11), 1349-458.

Celis, J. E., Rasmussen, H. H., Gromov, P., Olsen, E., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., Vorum, H. & Kristensen, D. B. (1995). The human keratinocyte two-dimensional gel protein database (update 1995): mapping components of signal transduction pathways. Electrophoresis, 16(12), 2177-240.

Celis, J. E., Rasmussen, H. H., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., Gesser, B., Olsen, E., Gromov, P. & Hoffmann, H. J. (1992). The human keratinocyte two-dimensional gel protein database (update 1992): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases. Electrophoresis, 13(12), 893-959.

Kozyraki, R., Kristiansen, M., Silahtaroglu, A., Hansen, C., Jacobsen, C., Tommerup, N., Verroust, P. J. & Moestrup, S. K. (1998). The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region. Blood, 91(10), 3593-600.

Bundgaard-Nielsen, C., Hansen, A. S., Lauritsen, M. B., Nyegaard, M., Hagstrøm, S. & Sørensen, S. (2017). The Human Gut Microbiota and its Role in ADHD and Autism Spectrum Disorder. Poster-session præsenteret på Årsmøde i Dansk Selskab for Toksikologi og Farmakologi.

Stover, C., Endo, Y., Takahashi, M., Lynch, N. J., Constantinescu, C., Vorup-Jensen, T., Thiel, S., Friedl, H., Hankeln, T., Hall, R., Gregory, S., Fujita, T. & Schwaeble, W. (2001). The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3. Genes and Immunity, 2(3), 119-27. https://doi.org/10.1038/sj.gene.6363745

Hansen, R. S., Thuesen, K. K., Bregnhøj, A., Moldovan, L. I., Kristensen, L. S., Grek, C. L., Ghatnekar, G. S., Iversen, L. & Johansen, C. (2021). The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes. Experimental Dermatology, 30(6), 773-781. https://doi.org/10.1111/exd.14302

Bross, P., Naundrup, S., Hansen, J., Nielsen, M. N., Christensen, J. H., Kruhøffer, M., Palmfeldt, J., Corydon, T. J., Gregersen, N., Ang, D., Georgopoulos, C. & Nielsen, K. L. (2008). The Hsp60-(p.V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo. Journal of Biological Chemistry, 283(23), 15694-700. https://doi.org/10.1074/jbc.M800548200

Magnoni, R., Palmfeldt, J., Hansen, J., Christensen, J. H., Corydon, T. J. & Bross, P. (2013). The Hsp60 Folding Machinery Is Crucial For Manganese Superoxide Dismutase Folding And Function. Free Radical Research. https://doi.org/10.3109/10715762.2013.858147

Ennibi, O.-K., Benrachadi, L., Bouziane, A., Haubek, D. & Poulsen, K. (2012). The highly leukotoxic JP2 clone of Aggregatibacter actinomycetemcomitans in localized and generalized forms of aggressive periodontitis. Acta Odontologica Scandinavica, 70(4), 318-322. https://doi.org/10.3109/00016357.2011.642002

Haubek, D., Ennibi, O.-K., Poulsen, K., Benzarti, N. & Baelum, V. (2004). The highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans and progression of periodontal attachment loss. Journal of Dental Research, 83(10), 767-70.

Farahani, E., Reinert, L. S., Narita, R., Serrero, M. C., Skouboe, M. K., van der Horst, D., Assil, S., Zhang, B., Iversen, M. B., Gutierrez, E., Hazrati, H., Johannsen, M., Olagnier, D., Kunze, R., Denham, M., Mogensen, T. H., Lappe, M. & Paludan, S. R. (2024). The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation. Cell Reports, 43(2), 113792. Artikel 113792. https://doi.org/10.1016/j.celrep.2024.113792

Stempel, M., Chan, B., Juranić Lisnić, V., Krmpotić, A., Hartung, J., Paludan, S. R., Füllbrunn, N., Lemmermann, N. A. W. & Brinkmann, M. M. (2019). The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. EMBO Journal, 38(5), Artikel e100983. https://doi.org/10.15252/embj.2018100983

Curwen, G. B., Cadwell, K. K., Winther, J. F., Tawn, E. J., Rees, G. S., Olsen, J. H., Rechnitzer, C. M. A., Schroeder, H., Guldberg, P., Cordell, H. J. & Boice, J. D. (2010). The heritability of G2 chromosomal radiosensitivity and its association with cancer in Danish cancer survivors and their offspring. International Journal of Radiation Biology, 86(11), 986-95. https://doi.org/10.3109/09553002.2010.496027

Dunaway, L. S., Saii, K., LoBue, A., Nyshadham, S., Abib, N., Heuser, S. K., Loeb, S. A., Simonsen, U., Cortese-Krott, M. M. & Isakson, B. E. (2024). The hemodynamic response to nitrite is acute and dependent upon tissue perfusion. Nitric Oxide: Biology and Chemistry, 150, 47-52. https://doi.org/10.1016/j.niox.2024.07.005

Abdallah, H. B., Marino, G., Idorn, M., Reinert, L. S., Bregnhøj, A., Paludan, S. R. & Johansen, C. (2024). The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice. PLoS One, 19(9), Artikel e0310915. https://doi.org/10.1371/journal.pone.0310915

Thomsen, J. H., Etzerodt, A., Svendsen, P. & Moestrup, S. K. (2013). The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging. Oxidative Medicine and Cellular Longevity, 2013, 523652. https://doi.org/10.1155/2013/523652

Bech, P., Allerup, P., Larsen, E. R., Csillag, C. & Licht, R. W. (2014). The Hamilton Depression Scale (HAM-D) and the Montgomery-Åsberg Depression Scale (MADRS). A psychometric re-analysis of the European Genome-Based Therapeutic Drugs for Depression Study using Rasch analysis. Psychiatry Research. https://doi.org/10.1016/j.psychres.2014.03.024

Kilian, M. (1976). The haemolytic activity of Haemophilus species. Acta Pathologica et Microbiologica Scandinavica APMIS, 84B(6), 339-41.

Füllbrunn, N., Nicastro, R., Mari, M., Griffith, J., Herrmann, E., Rasche, R., Borchers, A.-C., Auffarth, K., Kümmel, D., Reggiori, F., De Virgilio, C., Langemeyer, L. & Ungermann, C. (2024). The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes. The Journal of Cell Biology, 223(6), Artikel e202305038. https://doi.org/10.1083/jcb.202305038

Mattu, T. S., Pleass, R. J., Willis, A. C., Kilian, M., Wormald, M. R., Lellouch, A. C., Rudd, P. M., Woof, J. M. & Dwek, R. A. (1998). The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions. Journal of Biological Chemistry, 273(4), 2260-72.

Thomsen, C., Rasmussen, O. W., Christiansen, C., Andreasen, F., Poulsen, P. L. & Hermansen, K. (1994). The glycaemic index of spaghetti and gastric emptying in non-insulin-dependent diabetic patients. European Journal of Clinical Nutrition, 48(11), 776-80.

Damkjær, M., Wang, T., Brøndum, E., Østergaard, K. H., Baandrup, U., Hørlyck, A., Hasenkam, J. M., Smerup, M. H., Funder, J., Marcussen, N., Danielsen, C. C., Bertelsen, M. F., Grøndahl, C., Pedersen, M., Agger, P., Candy, G., Aalkjær, C. & Bie, P. (2015). The giraffe kidney tolerates high arterial blood pressure by high renal interstitial pressure and low glomerular filtration rate. Acta Physiologica, 214(4), 497-510. https://doi.org/10.1111/apha.12531

Staunstrup, N. H., Starnawska, A., Nyegaard, M., Nielsen, A. L., Borglum, A. D. & Mors, O. (2017). The Genome-Wide DNA Methylation Profile of Peripheral Blood Is Not Systematically Changed by Short-Time Storage at Room Temperature. Epigenomes, 1(3), Artikel 23. https://doi.org/10.3390/epigenomes1030023

Henne, A., Brüggemann, H., Raasch, C., Wiezer, A., Hartsch, T., Liesegang, H., Johann, A., Lienard, T., Gohl, O., Martinez-Arias, R., Jacobi, C., Starkuviene, V., Schlenczeck, S., Dencker, S., Huber, R., Klenk, H.-P., Kramer, W., Merkl, R., Gottschalk, G. & Fritz, H.-J. (2004). The genome sequence of the extreme thermophile Thermus thermophilus. Nature Biotechnology, 22(5), 547-53. https://doi.org/10.1038/nbt956

Brüggemann, H., Baumer, S., Fricke, W. F., Wiezer, A., Liesegang, H., Decker, I., Herzberg, C., Martinez-Arias, R., Merkl, R., Henne, A. & Gottschalk, G. (2003). The genome sequence of Clostridium tetani, the causative agent of tetanus disease. Proceedings of the National Academy of Sciences (PNAS), 100(3), 1316-21. https://doi.org/10.1073/pnas.0335853100

Huang, S., Li, R., Zhang, Z., Li, L., Gu, X., Fan, W., Lucas, W. J., Wang, X., Xie, B., Ni, P., Ren, Y., Zhu, H., Li, J., Lin, K., Jin, W., Fei, Z., Li, G., Staub, J., Kilian, A. ... Li, S. (2009). The genome of the cucumber, Cucumis sativus L. Nature Genetics, 41(12), 1275-81. https://doi.org/10.1038/ng.475

Deppenmeier, U., Johann, A., Hartsch, T., Merkl, R., Schmitz, R. A., Martinez-Arias, R., Henne, A., Wiezer, A., Bäumer, S., Jacobi, C., Brüggemann, H., Lienard, T., Christmann, A., Bömeke, M., Steckel, S., Bhattacharyya, A., Lykidis, A., Overbeek, R., Klenk, H.-P. ... Gottschalk, G. (2002). The genome of Methanosarcina mazei: evidence for lateral gene transfer between bacteria and archaea. Journal of Molecular Microbiology and Biotechnology, 4(4), 453-61.

Seedorf, H., Fricke, W. F., Veith, B., Brüggemann, H., Liesegang, H., Strittmatter, A., Miethke, M., Buckel, W., Hinderberger, J., Li, F., Hagemeier, C., Thauer, R. K. & Gottschalk, G. (2008). The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features. Proceedings of the National Academy of Sciences (PNAS), 105(6), 2128-33. https://doi.org/10.1073/pnas.0711093105

Klee, S. R., Brzuszkiewicz, E. B., Nattermann, H., Brüggemann, H., Dupke, S., Wollherr, A., Franz, T., Pauli, G., Appel, B., Liebl, W., Couacy-Hymann, E., Boesch, C., Meyer, F.-D., Leendertz, F. H., Ellerbrok, H., Gottschalk, G., Grunow, R. & Liesegang, H. (2010). The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids. PLoS One, 5(7), e10986. https://doi.org/10.1371/journal.pone.0010986

Coleman, J. R. I., Gaspar, H. A., Bryois, J., Breen, G., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J. H. (2020). The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Biological Psychiatry, 88(2), 169-184. https://doi.org/10.1016/j.biopsych.2019.10.015

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Revideret 21.08.2025