Institut for Biomedicin - Medarbejderportal

Peer-reviewed publikationer

Peer-reviewed publications

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Aalkjær, C. & Wang, T. (2021). The remarkable cardiovascular system of giraffes. Annual Review of Physiology, 83, 1-15. https://doi.org/10.1146/annurev-physiol-031620-094629

Holmgaard, K., Aalkjaer, C., Lambert, J. D. C., Hessellund, A. & Bek, T. (2007). The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition. Acta Ophthalmologica, 86(1), 26-33. https://doi.org/10.1111/j.1600-0420.2007.01010.x

Jensen, K. H., Aalkjær, C., Lambert, J. D. C., Hessellund, A. & Bek, T. (2008). The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition. Acta Ophthalmologica, 86, 26-33.

Andreassen, O. A., Finsen, B., Ostergaard, K., Sørensen, J. C., West, M. J. & Jørgensen, H. A. (1999). The relationship between oral dyskinesias produced by long-term haloperidol treatment, the density of striatal preproenkephalin messenger RNA and enkephalin peptide, and the number of striatal neurons expressing preproenkephalin messenger RNA in rats. Neuroscience, 88(1), 27-35.

Hansen, T. F., Andersen, C. L., Spindler, K.-L. G., Sørensen, F. B., Lindebjerg, J., Brandslund, I. & Jakobsen, A. (2010). The relationship between miRNA-126, vascular endothelial growth factor receptor 2 and neoangiogenesis in patients with colorectal cancer.

Hansen, T. F., Christensen, R. D., Andersen, R. F., Spindler, K.-L. G., Sørensen, F. B., Johnsson, A. & Jakobsen, A. (2012). The relationship between microRNA-126 and maintenance therapy with bevacizumab after chemotherapy plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer: Results of the phase III Nordic ACT trial NCT00598156 translational study.

Jensen, M. S. & Yaari, Y. (1988). The relationship between interictal and ictal paroxysms in an in vitro model of focal hippocampal epilepsy. Annals of Neurology, 24(5), 591-8. https://doi.org/10.1002/ana.410240502

Nielsen, D. G., Gotzsche, O., Sonne, O. & Eika, B. (2012). The relationship between immediate relevant basic science knowledge and clinical knowledge: physiology knowledge and transthoracic echocardiography image interpretation. Advances in Health Sciences Education, 17(4), 501. https://doi.org/10.1007/s10459-011-9327-y

Hokland, P., Hokland, M. & Heron, I. (1982). The relationship between human T-lymphocyte subsets defined by monoclonal antibodies and by avidity differences to sheep erythrocytes. Acta Pathologica et Microbiologica Scandinavica APMIS, 90(2), 105-8.

Bunger, MH., Andersen, T., Sorensen, L., Oxlund, H., Lind, M., Eriksen, EF., Bunger, C. & Langdahl, B. (2002). The relationship between growth factor mRNA and protein levels in human bone. Journal of Bone and Mineral Research (JBMR), 17, S428-S428.

Sanchez-Guajardo, V., Tentillier, N. & Romero-Ramos, M. (2015). The relation between α-synuclein and microglia in Parkinson's Disease: Recent developments. Neuroscience. https://doi.org/10.1016/j.neuroscience.2015.02.008

Sihm, I., Schroeder, A. P., Aalkjær, C., Holm, M., Mørn, B., Mulvany, M., Thygesen, K. & Lederballe, O. (1995). The relation between peripheral vascular structure, left ventricular hypertrophy, and ambulatory blood pressure in essential hypertension. American Journal of Hypertension, 8(10 Pt 1), 987-996.

Scuteri, A., Jensen, P. E. & Aalkjær, C. (1995). The regulation of pH in resistance arteries from spontaneously hypertensive and Wistar-Kyoto rats: the effect of bicarbonate. Journal of Hypertension, 13(5), 523-528.

Thomsen, T., Moeller, J. B., Schlosser, A., Sorensen, G. L., Moestrup, S. K., Palaniyar, N., Wallis, R., Mollenhauer, J. & Holmskov, U. (2010). The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition. Journal of Biological Chemistry, 285(2), 1229-38. https://doi.org/10.1074/jbc.M109.061523

Stover, C. M., Thiel, S., Lynch, N. J. & Schwaeble, W. J. (1999). The rat and mouse homologues of MASP-2 and MAp19, components of the lectin activation pathway of complement. Journal of Immunology, 163(12), 6848-59.

Einholm, A. P., Toustrup-Jensen, M. S., Holm, R., Andersen, J. P. & Vilsen, B. (2010). The rapid-onset dystonia Parkinsonism mutation D923N of the Na⁺,K⁺-ATPase alpha-3 isoform disrupts Na⁺interaction at the third Na⁺ site. Journal of Biological Chemistry, 285(34), 26245-26254.

Andrade, F. R. T., Buchborn, T., Thalheimer, G., Meinhardt, M. W., Joca, S. & De Almeida, R. M. M. (2025). Therapeutic Use of Psilocybin in Depression: A Systematic Review of Clinical Evidence. Acta Neuropsychiatrica, 37, Artikel e86. https://doi.org/10.1017/neu.2025.10039

Rasmussen, R. K. & Etzerodt, A. (2021). Therapeutic targeting of tumor-associated macrophages. I Advances in Immunopharmacology (s. 185-211). Academic Press. https://doi.org/10.1016/bs.apha.2021.03.002

Bjarkam, C. & Sørensen, J. C. H. (2004). Therapeutic strategies for neurodegenerative disorders: Emerging clues from Parkinson's disease. Biological Psychiatry, 56(4), 213-216. https://doi.org/10.1016/j.biopsych.2003.12.025

Nielsen, L. P. & Dahl, R. (2000). Therapeutic ratio of inhaled corticosteroids in adult asthma. A dose-range comparison between fluticasone propionate and budesonide, measuring their effect on bronchial hyperresponsiveness and adrenal cortex function. American Journal of Respiratory and Critical Care Medicine, 162(6), 2053-7. https://doi.org/10.1164/ajrccm.162.6.9912072

Guldager, M. B., Chaves Filho, A. M., Biojone, C. & Joca, S. (2024). Therapeutic potential of cannabidiol in depression. I Cannabidiol in Neurology and Psychiatry (Bind 177, s. 251-293). Academic Press. https://doi.org/10.1016/bs.irn.2024.06.001

Axelgaard, E., Jensen, T. I. & Bak, R. O. (2019). Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British Journal of Haematology, 185(5), 821-835. https://doi.org/10.1111/bjh.15851

Olesen, M. S., Hauge, B., Ohrt, L., Olesen, T. N., Roskær, J., Bæk, V., Elbæk, H. O., Nøhr, B., Nyegaard, M., Overgaard, M. T., Humaidan, P., Forman, A. & Agerholm, I. (2019). Therapeutic endometrial scratching and implantation after in vitro fertilization: a multicenter randomized controlled trial. Fertility and Sterility, 112(6), 1015-1021. https://doi.org/10.1016/j.fertnstert.2019.08.010

Henriksen, J., Andersen, C. U., Donskov, F., Hoffmann-Lücke, E., Greibe, E. & Fristrup, N. (2025). Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKI) for optimized outcome in patients with metastatic renal cell carcinoma. The TKI-TDM Trial. Study protocol. Acta Oncologica, 64, 729-733. https://doi.org/10.2340/1651-226X.2025.43693

Julander, J. G., Anderson, N., Haese, N., Andoh, T., Streblow, D. N., Cortez, P., Carter, K., Marniquet, X., Watson, H. & Mandron, M. (2022). Therapeutic and prophylactic treatment with a virus-specific antibody is highly effective in rodent models of Chikungunya infection and disease. Antiviral Research, 202, Artikel 105295. https://doi.org/10.1016/j.antiviral.2022.105295

Yang, C., Gao, S., Song, P., Dagnæs-Hansen, F., Jakobsen, M. V. & Kjems, J. (2018). Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. A C S Applied Materials and Interfaces, 10(23), 19494–19503. https://doi.org/10.1021/acsami.8b05513

Christiansen, S. H., Zhang, X., Juul-Madsen, K., Hvam, M. L., Vad, B. S., Behrens, M. A., Thygesen, I. L., Jalilian, B., Pedersen, J. S., Howard, K., Otzen, D. E. & Vorup-Jensen, T. (2017). The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage. Biochimica et biophysica acta - Biomembranes, 1859(3), 425-437. https://doi.org/10.1016/j.bbamem.2017.01.001

Thomsen, J. S., Andreasen, C. M., Bakalova, L. P., Brüel, A., Hauge, E. M., Eschen, G. E. T., Kiil, B. J., Delaisse, J.-M., Kersh, M. E. & Levin Andersen, T. (2016). The radial distribution of the intracortical porosity within the fibula diaphysis. Poster-session præsenteret på Annual meating American Society of Bone and Mineral Research, Atlanta, Georgia, USA.

Soerensen, A. L., Nielsen, L. P., Poulsen, B. K., Lisby, M. & Mainz, J. (2014). The Quality of Prescribing for Psychiatric Patients. Value in Health, 17(7), A455. https://doi.org/10.1016/j.jval.2014.08.1246

Paternoster, V., Cömert, C., Kirk, L. S., la Cour, S. H., Fryland, T., Fernandez-Guerra, P., Stougaard, M., Nyengaard, J. R., Qvist, P., Bross, P., Børglum, A. D. & Christensen, J. H. (2022). The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation. Translational Psychiatry, 12(1), Artikel 319. https://doi.org/10.1038/s41398-022-02053-2

Braun, F., Rinschen, M., Buchner, D., Bohl, K., Plagmann, I., Bachurski, D., Richard Späth, M., Antczak, P., Göbel, H., Klein, C., Lackmann, J.-W., Kretz, O., Puelles, V. G., Wahba, R., Hallek, M., Schermer, B., Benzing, T., Huber, T. B., Beyer, A. ... Müller, R.-U. (2020). The proteomic landscape of small urinary extracellular vesicles during kidney transplantation. Journal of Extracellular Vesicles, 10(1), Artikel e12026. https://doi.org/10.1002/jev2.12026

Lindegaard Pedersen, M., Krüger, M., Grimm, D., Infanger, M. & Wehland, M. (2020). The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension. Basic & Clinical Pharmacology & Toxicology, 126(1), 32-42. https://doi.org/10.1111/bcpt.13305

Carlo, A.-S., Gustafsen, C., Mastrobuoni, G., Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M., Nykjaer, A., Herz, J., Heeren, J., Kempa, S., Petersen, C. M. & Willnow, T. E. (2013). The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain. Journal of Neuroscience, 33(1), 358-70. https://doi.org/10.1523/JNEUROSCI.2425-12.2013

Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hørslev-Pedersen, K., Hetland, M. L., Stengaard-Pedersen, K., Østergaard, M., Ørnbjerg, L., Junker, P., Sharpe, A. H., Freeman, G. J., Hvid, M., Moestrup, S. K., Hauge, E. M. & Deleuran, B. (2022). The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings. Frontiers in Immunology, 13, Artikel 773946. https://doi.org/10.3389/fimmu.2022.773946

Duus Holle, S. L., Søholm, H., Møller, J. E., Winther-Jensen, M., Kunkel, J. B., Okkels Jensen, L., Kjærgaard, J., Lindholm, M. G., Helgestad, O. K. L., Wiberg, S., Sousa, R. R., Holmvang, L., Thomsen, J. H., Goetze, J. P., Hassager, C. & Frydland, M. (2025). The prognostic value of neurohormonal and inflammatory biomarkers in addition to the TIMI risk score in patients with ST-elevation myocardial infarction. Biomarkers, 30(1), 1-9. https://doi.org/10.1080/1354750X.2024.2435866

Korsgaard, U., Kristensen, M. P., García-Rodríguez, J. L., Kjær-Frifeldt, S., Lindebjerg, J., Hansen, T. F., Kjems, J., Hager, H. & Kristensen, L. S. (2025). The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population-based cohort study. International Journal of Cancer, 157(8), 1746-1755. https://doi.org/10.1002/ijc.35507

Jakobsen, T., Pløen, G. G., Behsen, A. D., Møller, H. J., Plesner, T., Dybkær, K., Andersen, M. N., Misund, K. & Kristensen, L. S. (2024). The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells. Journal of Cellular and Molecular Medicine, 28(22), Artikel e70215. https://doi.org/10.1111/jcmm.70215

Kjær-Frifeldt, S., Hansen, T. F., Nielsen, B. S., Lindebjerg, J., Christensen, R. D., Sørensen, F. B. & Jakobsen, A. (2012). The prognostic importance of miRNA-21 in stage II colon cancer. A population based study.

Glerup, S., Kløverpris, S. & Oxvig, C. (2006). The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region. Journal of Biological Chemistry, 281(42), 31509-31516. https://doi.org/10.1074/jbc.M605824200

Degn, S. E., Jensenius, J. C. & Thiel, S. (2014). The pro-factor D cleaving activity of MASP-1/-3 is not required for alternative pathway function. Journal of Immunology, 192(12), 5447-8. https://doi.org/10.4049/jimmunol.1400777

Fejerskov, O. & Larsen, M. J. (2025). The Process of de- and remineralization - the Key to Understanding Clinical Manifestations of Dental Caries. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 181-197). Wiley-Blackwell.

Engbjerg, J. S., Costanzo, V., Sardella, D., Bordoni, L., Jakobsen, S., D'Apolito, L., Frøkiær, J., Trepiccione, F., Capasso, G. & Frische, S. (2022). The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo. Molecular Imaging, 2022, Artikel 7908357. https://doi.org/10.1155/2022/7908357

Jan, A., Gonçalves, N. P., Vaegter, C. B., Jensen, P. H. & Ferreira, N. (2021). The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease: Update on Models and Hypotheses. International Journal of Molecular Sciences , 22(15), Artikel 8338. https://doi.org/10.3390/ijms22158338

Prætorius, H. (2015). The primary cilium as sensor of fluid flow: new building blocks to the model: A review in the theme: cell signaling: proteins, pathways and mechanisms. American Journal of Physiology: Cell Physiology, 308, C198.

Hennings, V., Thörn, K., Albinsson, S., Lingblom, C., Andersson, K., Andersson, C., Järbur, K., Pullerits, R., Idorn, M., Paludan, S. R., Eriksson, K. & Wennerås, C. (2022). The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from COVID-19. European Journal of Immunology, 52(5), 800-809. https://doi.org/10.1002/eji.202149655

Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022). The presence of interferon affects the progression of non-alcoholic fatty liver disease. Genes and Immunity, 23(5), 157–165. https://doi.org/10.1038/s41435-022-00176-6

Hansen, T. F., Sørensen, F. B. & Lindebjerg, J. (2011). The predictive value of miRNA in relation to first line capecitabine and oxaliplatin in patients with metastatic colorectal cancer.

West, M. J. (2012). The precision of estimates in stereological analyses. Cold Spring Harbor Protocols, 2012(9), 937-49. https://doi.org/10.1101/pdb.top071050

Matrone, C. & Brattico, E. (2015). The Power of music on Alzheimer ’s Disease and the need to understand the underlying molecular mechanisms. Journal of Alzheimer's disease and parkinsonism, 5(3). https://doi.org/10.4172/2161-0460.1000196

Lin, X., Stenvang, J., Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N. (2015). The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer. BMC Genomics, 16, 404. https://doi.org/10.1186/s12864-015-1552-y

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Revideret 21.08.2025