Peer-reviewed publikationer

Peer-reviewed publications

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Breinbjerg, A., Jørgensen, C. S., Borg, B., Rittig, S., Kamperis, K. & Christensen, J. H. (2023). The genetics of incontinence: A scoping review. Clinical Genetics, 104(1), 22-62. https://doi.org/10.1111/cge.14331

Christiansen, C., Hansen, E. & Christiansen, G. (1984). The genetic relation of M. hominis to other Mycoplama species. Sexually Transmitted Diseases, 10, 230-231.

Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Werge, T. M., Melbye, M., Hougaard, D. M., Larsen, L. A., Christensen, S. T. & Christiansen, M. (2023). The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement. Brain Communications, 5(1), Artikel fcad004. https://doi.org/10.1093/braincomms/fcad004

Laisk, T., Soares, A. L. G., Ferreira, T., Painter, J. N., Censin, J. C., Laber, S., Bacelis, J., Chen, C.-Y., Lepamets, M., Lin, K., Liu, S., Millwood, I. Y., Ramu, A., Southcombe, J., Andersen, M. S., Yang, L., Becker, C. M., Børglum, A. D., Gordon, S. D. ... Lindgren, C. M. (2020). The genetic architecture of sporadic and multiple consecutive miscarriage. Nature Communications, 11(1), Artikel 5980. https://doi.org/10.1038/s41467-020-19742-5

Mahjani, B., Klei, L., Mattheisen, M., Halvorsen, M. W., Reichenberg, A., Roeder, K., Pedersen, N. L., Boberg, J., de Schipper, E., Bulik, C. M., Landén, M., Fundín, B., Mataix-Cols, D., Sandin, S., Hultman, C. M., Crowley, J. J., Buxbaum, J. D., Rück, C., Devlin, B. & Grice, D. E. (2022). The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. American Journal of Psychiatry, 179(3), 216-225. https://doi.org/10.1176/appi.ajp.2021.21010101

Giannakopoulou, O., Lin, K., Meng, X., Su, M.-H., Kuo, P.-H., Peterson, R. E., Awasthi, S., Moscati, A., Coleman, J. R. I., Bass, N., Millwood, I. Y., Chen, Y., Chen, Z., Chen, H.-C., Lu, M.-L., Huang, M.-C., Chen, C.-H., Stahl, E. A., Loos, R. J. F. ... 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. JAMA Psychiatry, 78(11), 1258-1269. https://doi.org/10.1001/jamapsychiatry.2021.2099

Andreasen, C. M., Bakalova, L. P., Brüel, A., Hauge, E. M., Kiil, B. J., Delaisse, J.-M., Kersh, M. E., Thomsen, J. S. & Andersen, T. L. (2020). The generation of enlarged eroded pores upon existing intracortical canals is a major contributor to endocortical trabecularization. Bone, 130, Artikel 115127. https://doi.org/10.1016/j.bone.2019.115127

Demontis, D., Nyegaard, M., Christensen, J. H., Severinsen, J., Hedemand, A., Hansen, T., Werge, T., Mors, O. & Børglum, A. D. (2012). The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case-control sample. Psychiatric Genetics, 22(2), 62-9. https://doi.org/10.1097/YPG.0b013e32834dc424

Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K., Gjesing, A., Nielsen, A., Albrechtsen, A., Rasmussen, S., Jørgensen, T., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Madsbad, S., Hansen, T. & Pedersen, O. B. (2007). The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes. Diabetologia, 51(1), 70-75. https://doi.org/10.1007/s00125-007-0865-z

Pihakaski-Maunsbach, K., Tokonabe, S., Vorum, H., Rivard, C., Capasso, J., Berl, T. & Maunsbach, A. B. (2005). The gamma-subunit of Na,K-ATPase is incorporated into plasma membranes of mouse IMCD3 cells in response to hypertonicity. American Journal of Physiology: Renal Physiology, 288, F650-F657.

Walter, A. (2024). The function of web decorations in orb web spiders. Frontiers in Arachnid Science, 3, 1-22. Artikel https://doi.org/10.3389/frchs.2024.1384128. https://www.frontiersin.org/articles/10.3389/frchs.2024.1384128/full

Andersen, J. P., Møller, J. V. & Jørgensen, P. L. (1982). The functional unit of sarcoplasmic reticulum Ca2+-ATPase. Active site titration and fluorescence measurements. Journal of Biological Chemistry, 257(14), 8300-8307.

Andersen, G., Dalgaard, L. T., Justesen, J. M., Anthonsen, S., Nielsen, T., Thørner, L. W., Witte, D., Jørgensen, T., Clausen, J. O., Lauritzen, T., Holmkvist, J., Hansen, T. & Pedersen, O. B. (2013). The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes. International Journal of Obesity, 37(2), 175-81. https://doi.org/10.1038/ijo.2012.22

Overgaard-Steensen, C., Stødkilde-Jørgensen, H., Larsson, A., Tønnesen, E., Frøkiaer, J. & Ring, T. (2016). The frequently used intraperitoneal hyponatraemia model induces hypovolaemic hyponatraemia with possible model-dependent brain sodium loss. Experimental Physiology, 101.7(7), 932-945. https://doi.org/10.1113/EP085751

Kamm, C., Healey, D. G., Quinn, N. P., Wüllner, U., Müller, J. C., Schols, L., Geser, F., Burk, K., Børglum, A., Pellecchia, M. T., Tolosa, E., del Sorbo, F., Nilsson, C., Bandmann, O., Sharma, M., Mayer, P., Gasteiger, M., Haworth, A., Ozawa, T. ... Gasser, T. (2005). The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group. Brain, 128, 1855-1860.

Barkia, B., Sandt, V., Melnik, D., Cortés-Sánchez, J. L., Marchal, S., Baselet, B., Baatout, S., Sahana, J., Grimm, D., Wehland, M., Schulz, H., Infanger, M., Kraus, A. & Krüger, M. (2024). The Formation of Stable Lung Tumor Spheroids during Random Positioning Involves Increased Estrogen Sensitivity. Biomolecules, 14(10), Artikel 1292. https://doi.org/10.3390/biom14101292

Krimpenfort, L. T., Degn, S. E. & Heesters, B. A. (2024). The follicular dendritic cell: At the germinal center of autoimmunity? Cell Reports, 43(3), Artikel 113869. https://doi.org/10.1016/j.celrep.2024.113869

Jensen, I. S., Yuan, J., He, J., Lin, L., Sander, B. & Golas, M. M. (2019). The FlpTRAP system for purification of specific, endogenous chromatin regions. Analytical Biochemistry, 587, Artikel 113418. https://doi.org/10.1016/j.ab.2019.113418

Brüggemann, H., Lomholt, H. B. & Kilian, M. (2012). The flexible gene pool of Propionibacterium acnes. Mobile Genetic Elements, 2(3), 145-148. https://doi.org/10.4161/mge.21204

Clarkson, A. N., Boothman-Burrell, L., Dósa, Z., Nagaraja, R. Y., Jin, L., Parker, K., van Nieuwenhuijzen, P. S., Neumann, S., Gowing, E. K., Gavande, N., Ahring, P. K., Holm, M. M., Hanrahan, J. R., Nicolazzo, J. A., Jensen, K. & Chebib, M. (2019). The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia. Journal of Cerebral Blood Flow and Metabolism, 39(7), 1266-1282. https://doi.org/10.1177/0271678X18755628

Ernst, E., Bergholdt, S., Jørgensen, J. S. & Andersen, C. Y. (2010). The first woman to give birth to two children following transplantation of frozen/thawed ovarian tissue. Human Reproduction, 25(5), 1280-81. https://doi.org/10.1093/humrep/deq033

Yonehara, K., Farrow, K., Ghanem, A., Hillier, D., Balint, K., Teixeira, M., Jüttner, J., Noda, M., Neve, R. L., Conzelmann, K.-K. & Roska, B. (2013). The first stage of cardinal direction selectivity is localized to the dendrites of retinal ganglion cells. Neuron, 79(6), 1078-85. https://doi.org/10.1016/j.neuron.2013.08.005

Wulfmeyer, V. C. & Rinschen, M. M. (2025). The final frontier: kidney function, omics and deterioration in space. Kidney International, 107(3), 382-384. https://doi.org/10.1016/j.kint.2024.11.011

Klemm, P. & Christiansen, G. (1990). The fimD gene required for cell surface localization of Escherichia coli type 1 fimbriae. Mol. Gen. Genet ., 220, 334-338.

Grimm, D., Schulz, H., Krüger, M., Cortés-Sánchez, J. L., Egli, M., Kraus, A., Sahana, J., Corydon, T. J., Hemmersbach, R., Wise, P. M., Infanger, M. & Wehland, M. (2022). The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model. International Journal of Molecular Sciences , 23(6), Artikel 3073. https://doi.org/10.3390/ijms23063073

Fischer, D., Seifen, C., Baer, P., Jung, M., Mertens, C., Scheller, B., Zacharowski, K., Hofmann, R., Maier, T. J. & Urbschat, A. (2018). The fibrin cleavage product Bβ15-42 channels endothelial and tubular regeneration in the post-acute course during murine renal ischemia reperfusion injury. Frontiers in Pharmacology, 9(APR), Artikel 369. https://doi.org/10.3389/fphar.2018.00369

Pedersen, L., Eriksen, L. L., Brix, F. H., Vilstrup, H., Deleuran, B., Sandahl, T. D. & Støy, S. (2025). The FGL-1/LAG-3 Axis is Associated With Disease Course in Alcohol-associated Hepatitis: A Preliminary Report. Journal of Clinical and Experimental Hepatology, 15(1), Artikel 102424. https://doi.org/10.1016/j.jceh.2024.102424

Philip, J., Christensen, B. & Kølvraa, S. (2005). [The fetal erythroblast is not the optimal target for non-invasive prenatal diagnosis--secondary publication]. Ugeskrift for Læger, 167(15), 1644-1646.

Kølvraa, S., Christensen, B., Lykke-Hansen, L. & Philip, J. (2005). The fetal erythroblast is not the optimal target for non-invasive prenatal diagnosis: preliminary results. Journal of Histochemistry and Cytochemistry, 53(3), 331-336.

Wigdor, E. M., Weiner, D. J., Grove, J., Fu, J. M., Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M., Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022). The female protective effect against autism spectrum disorder. Cell Genomics, 2(6), Artikel 100134. https://doi.org/10.1016/j.xgen.2022.100134

FarmGTEx Consortium (2025). The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Nature Genetics, 57(4), 786-796. Artikel 604. https://doi.org/10.1038/s41588-025-02121-5

Voss, L. F., Howarth, A. J., Wittenborn, T. R., Hummelgaard, S., Juul-Madsen, K., Kastberg, K. S., Pedersen, M. K., Jensen, L., Papanastasiou, A. D., Vorup-Jensen, T., Weyer, K. & Degn, S. E. (2022). The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus. Frontiers in Immunology, 13, Artikel 1021370. https://doi.org/10.3389/fimmu.2022.1021370

Depner, M., Fuchs, S., Raabe, J., Frede, N., Glocker, C., Doffinger, R., Gkrania-Klotsas, E., Kumararatne, D., Atkinson, T. P., Schroeder, H. W., Niehues, T., Dückers, G., Stray-Pedersen, A., Baumann, U., Schmidt, R., Franco, J. L., Orrego, J., Ben-Shoshan, M., McCusker, C. ... Grimbacher, B. (2016). The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1. Journal of Clinical Immunology, 36(1), 73-84. https://doi.org/10.1007/s10875-015-0214-9

Vandahl, BB., Pedersen, AS., Gervaert, K., Holm, A., Vandekerckhove, J., Christiansen, G. & Birkelund, S. (2002). The expression, processing and localization of polymopphic membrane proteins in Chlamydia pneumoniae strain CWL029. BMC Microbiology, 2, 36.

Kragstrup, T. W., Otkjaer, K., Holm, C., Jørgensen, A., Hokland, M., Iversen, L. & Deleuran, B. W. (2008). The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine, 41(1), 16-23. https://doi.org/10.1016/j.cyto.2007.10.004

Klemm, P., Jørgensen, BJ., Kreft, B. & Christiansen, G. (1995). The export systems of type 1 and F1C fimbriae are interchangeable but work in parental pairs. J Bacteriol, 177, 621-627.

Jensen, P. H., Jensen, T. G., Laug, W. E., Hager, H., Gliemann, J. & Pepinsky, B. (1996). The exon 3 encoded sequence of the intracellular serine proteinase inhibitor plasminogen activator inhibitor 2 is a protein binding domain. Journal of Biological Chemistry, 271(43), 26892-9.

Andreasen, M. & Lambert, J. D. C. (1995). The excitability of CA1 pyramidaL cell dendrites is modulated by a local Ca2+-dependent K+-conductance. Brain Research, 698, 193-203.

AlZaim, I., de Rooij, L. P. M. H., Sheikh, B. N., Börgeson, E. & Kalucka, J. (2023). The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity. Nature Reviews Endocrinology, 19(12), 691-707. https://doi.org/10.1038/s41574-023-00893-6

Als, T. D., Vila, R., Kandul, N. P., Nash, D. R., Yen, S.-H., Hsu, Y.-F., Mignault, A. A., Boomsma, J. J. & Pierce, N. E. (2004). The evolution of alternative parasitic life histories in large blue butterflies. Nature, 432(7015), 386-90. https://doi.org/10.1038/nature03020

Hollyer, T. R., Bordoni, L., Kousholt, B. S., van Luijk, J., Ritskes-Hoitinga, M. & Østergaard, L. (2019). The evidence for the physiological effects of lactate on the cerebral microcirculation: a systematic review. Journal of Neurochemistry, 148(6), 712-730. https://doi.org/10.1111/jnc.14633

Bonde, J. P., Joffe, M., Danscher, G., Apostoli, P., Bisanti, L., Giwercman, A., Kolstad, H., Thonneau, P., Roeleveld, N. & Vanhoorne, M. (1999). The European Asclepios study on occupational hazards to male reproductive capability: Objectives, designs and populations. Scandinavian Journal of Work, Environment & Health, 25 Suppl 1, 49-61; discussion 76-8.

Kilian, M., Frandsen, E. V. G., Haubek, D. & Poulsen, K. (2006). The etiology of periodontal disease revisited by population genetic analysis. Periodontology, 41, 1-22.

Nexø, B. A., Christensen, T., Frederiksen, J., Møller-Larsen, A., Oturai, A. B., Villesen, P., Hansen, B., Nissen, K. K., Laska, M. J., Petersen, T. S., Bonnesen, S., Hedemand, A., Wu, T., Wang, X., Zhang, X., Brudek, T., Maric, R., Søndergaard, H., Sellebjerg, F. T. ... Pedersen, F. S. (2011). The Etiology of Multiple Sclerosis: Genetic Evidence for the Involvement of the Human Endogenous Retrovirus HERV-Fc1. PLoS One, 6(2), e16652. https://doi.org/10.1371/journal.pone.0016652

Christensen, T. & Muchardt, C. (2019). The epigenetics of multiple sclerosis. I O. Binda (red.), Chromatin Signaling and Neurological Disorders (s. 97-118). Academic Press.

Brix, J., Zhou, Y. & Luo, Y. (2015). The Epigenetic Reprogramming Roadmap in Generation of iPSCs from Somatic Cells. Journal of Genetics and Genomics.

Manji, F., Fejerskov, O., Bælum, V., Luan, W. M. & Chen, X. (1991). The epidemiological features of dental caries in African and Chinese populations: Implications for risk assessment. I N. W. Johnson (red.), Dental Caries: Markers of High and Low Risk Groups and Individuals (Bind 1, s. 62-99). Cambridge: Cambridge University Press.

Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C. ... the Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group (2014). The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. https://doi.org/10.1007/s11682-013-9269-5

Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S. (2018). The Endo-Lysosomal System of Brain Endothelial Cells Is Influenced by Astrocytes In Vitro. Molecular Neurobiology, 55(11), 8522-8537. https://doi.org/10.1007/s12035-018-0988-x

Toth, A. E., Nielsen, S. S. E., Tomaka, W., Abbott, N. J. & Nielsen, M. S. (2019). The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells. Fluids and Barriers of the CNS, 16(1), Artikel 14. https://doi.org/10.1186/s12987-019-0134-9

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