Peer-reviewed publikationer

Peer-reviewed publications

Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Als, T. D., Nissen, J. B., Meier, S. M., Mattheisen, M., PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025

Walker, A., Karlsson, R., Szatkiewicz, J. P., Thornton, L. M., Yilmaz, Z., Leppä, V. M., Savva, A., Lin, T., Sidorenko, J., McRae, A., Kirov, G., Davies, H. L., Fundín, B. T., Chawner, S. J. R. A., Song, J., Borg, S., Wen, J., Watson, H. J., Munn-Chernoff, M. A. ... Wray, N. R. (2025). Genome-wide copy number variation association study in anorexia nervosa. Molecular Psychiatry, 30(5), 2009-2016. Artikel 867. https://doi.org/10.1038/s41380-024-02811-2

Hansen, S. M., Koefoed-Nielsen, P., Clemmensen, T. S., Eiskjær, H. & Staunstrup, N. H. (2025). Genomic collision at the LIMS-1 locus increases risk of cellular mediated allograft rejection in heart transplanted recipients. Human Immunology, 86(1), 111189. Artikel 111189. https://doi.org/10.1016/j.humimm.2024.111189

Akter, H., Rahaman, M. A., Eshaque, T. B., Mohamed, N., Islam, A., Morshed, M., Shahin, Z., Muhaimin, A., Foyzullah, A. M., Mim, R. A., Omar, F. B., Hasan, M. N., Satsangi, D., Ahmed, N., Al Saba, A., Jahan, N., Hossen, M. A., Mondol, M. A., Sakib, A. S. ... Uddin, M. (2025). Genomic insights from a deeply phenotyped highly consanguineous neurodevelopmental disorders cohort. Genetics in Medicine, 27(1), Artikel 101282. https://doi.org/10.1016/j.gim.2024.101282

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

Borup, A., Sharifpour, M. F., Rossen, L. S., Whitehead, B., Boysen, A. T., Olesen, R., Bohn, A. B., Ridolfi, A., Brucale, M., Valle, F., Paolini, L., Radeghieri, A., Bergese, P., Miles, K., Veitch, M., Thomas, T., Ruscher, R., Wangchuk, P., Giacomin, P. ... Nejsum, P. (2025). Helminth extracellular vesicles co-opt host monocytes to drive T cell anergy. Journal of Extracellular Vesicles, 14(1), Artikel e70027. https://doi.org/10.1002/jev2.70027

Cham, L. B., Whitehead, B., Werner, M., Jensen, F., Zippor, M., Mogensen, T. H., Netea, M. G., Williams, A. R. & Nejsum, P. (2025). Helminth infection induces innate immune priming in plasmacytoid dendritic cells. The Journal of Infectious Diseases, 232(1), 230-235. https://doi.org/10.1093/infdis/jiaf009

Aalkjær, C., Damkjær, M., Baandrup, U. T., Bertelsen, M. F., Brøgger, T., Brøndum, E., Danielsen, C. C., Funder, J. A., Grøndahl, C., Hasenkam, J. M., Henriksen, P. G., Secher, N. H., Skovgaard, N., Smerup, M. H., Telinius, N., Østergaard, K. H., Bie, P. & Wang, T. (2025). Hemodynamics and Drinking in the Giraffe. Acta Physiologica, 241(5), 1-14. Artikel e70046. https://doi.org/10.1111/apha.70046

Andersen, H. H., Andersen, M. K., Bossow, K. A., Vestergaard, A. L., Bor, P. & Larsen, A. (2025). High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP. The Journal of Steroid Biochemistry and Molecular Biology, 250, Artikel 106742. https://doi.org/10.1016/j.jsbmb.2025.106742

Pedersen, M. N., Hybel, T. E., Bjerre, J. H., Hammer, A. S. B., Bohn, A. B., Bill, M., Rosenberg, C. A. & Ludvigsen, M. (2025). High-Efficiency Enrichment of Megakaryocytes and Identification of Micromegakaryocytes from Human Bone Marrow by Imaging Flow Cytometry. Cells, 14(8), Artikel 588. https://doi.org/10.3390/cells14080588

Borbye-Lorenzen, N., Holmgaard, S., Ottosson, F., Nudel, R., Appadurai, V., Laursen, T. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T., Benros, M. E., Hougaard, D. M. & Skogstrand, K. (2025). High level of immunoglobulin G targeting mycoplasma or cytomegalovirus in the newborn increases risk of ADHD. Brain, Behavior, and Immunity, 123, 99-107. https://doi.org/10.1016/j.bbi.2024.09.009

Larsen, M. L., Voss, A., Tandrup Holst Nielsen, C., Hauge, E. M., Faurschou, M. & Troldborg, A. (2025). Highlighting individual patient data related to chimeric antigen receptor T-cell therapy in refractory autoimmune rheumatic diseases. Scandinavian Journal of Rheumatology, 54(3), 219-224. https://doi.org/10.1080/03009742.2024.2421621

Hu, Y., Chourpiliadis, C., Ingre, C., Ahlqvist, V. H., Sun, J., Song, H., Pawitan, Y., Piehl, F. & Fang, F. (2025). Hospital-treated infections and the risk and prognosis of amyotrophic lateral sclerosis: A population-based study. Journal of Internal Medicine. Advance online publication. https://doi.org/10.1111/joim.70008

Al-Rousan, T., Naja, W., Wejse, C. M., Kaki, D., Aoun, M., Lange, S., Alshawabkeh, L., Alhamad, R., Kadri, N. & Eiset, A. H. (2025). Hypertension in Syrian refugees: prevalence, awareness, and access to care in Denmark and Lebanon. Frontiers in Public Health, 13, Artikel 1486806. https://doi.org/10.3389/fpubh.2025.1486806

Staehr, C., Hinkley, V., Matchkov, V. V., Rajanathan, R., Hansen, L. M. B., Eiby, Y., Luque, N., Wright, I., Bjorkman, S. T., Miller, S. M., Grimley, R. S., Dettrick, A., Chand, K., Nguyen, H. L., Jones, N. M., Murphy, T. V. & Sandow, S. L. (2025). Hypoxia and ischemic stroke modify cerebrovascular tone by upregulating endothelial BK(Ca) channels—Lessons from rat, pig, mouse, and human. Acta Physiologica (Print), 241(4), Artikel e70030. https://doi.org/10.1111/apha.70030

Jacobsen, V., Pan, V. A., Tran, L. T., Vohradsky, J., Bønnelykke, J., Schmidt Herø, C., Johansen, J. G., Tobias Frederiksen, A., Singers Sørensen, B., Busk, M., Sauerwein, W. A. G., Rosenfeld, A. B. & Bassler, N. (2025). In-vitro and microdosimetric study of proton boron capture therapy and neutron capture enhanced proton therapy. Physics in Medicine and Biology, 70(5). https://doi.org/10.1088/1361-6560/adb199

Gugu, M., Acharya, S., Pira, D., Poletti, S., di Flora, A., Saksida, T., Pilipenko, V., Romero-Ramos, M., Marino, F., Muñoz Delgado, L., Nikolovski, N., Gursoy Ozdemir, Y., Lawson, D., Comi, C. & Figueira, I. (2025). IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET. Open Research Europe, 4, Artikel 119. https://doi.org/10.12688/openreseurope.17547.2

Lewash, S. A., McKenney, V. R., Wuebben, C., Ludwig, J., Hosni, R., Radzey, D., Toma, M. I., Bartok, E., Schlee, M., Zillinger, T., Heckel, A. & Hartmann, G. (2025). Immunoengineering of a Photocaged 5´-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer. Angewandte Chemie - International Edition, 64(21), Artikel e202423321. https://doi.org/10.1002/anie.202423321

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, Artikel e1004092. Advance online publication. https://doi.org/10.1038/s41380-025-03032-x

El-Awaisi, J., Kavanagh, D., Heising, S., Schiessl, I. M., Cleary, S. J., Hodson, D. J. & Kalia, N. (2025). Impact of chronic hyperglycaemia on the coronary microcirculation – benefits of targeting IL-36 and diet reversal. Basic Research in Cardiology, 120(3), 509-526. Artikel 660698. https://doi.org/10.1007/s00395-025-01107-y

Andersen, J. W., Høgh, A., Lindholt, J. S., Søgaard, R., Støvring, H., Yderstræde, K. B., Sandbæk, A. & Dahl, M. (2025). Impact of population-based screening for diabetes and prediabetes among 67-year-olds using point-of-care Hba1c on healthcare ultilisation, results from the VISP cohort. Clinical epidemiology, 17, 75-85. https://doi.org/10.2147/CLEP.S487825

Bernth Jensen, J. M., Dinh, K. M., Hindhede, L., Erikstrup, L. T., Hansen, A. G., Hymøller, K. M., Ostrowski, S. R., Pedersen, O. B. V., Christiansen, S. H., Sørensen, U. B. S., Thiel, S. & Erikstrup, C. (2025). Impact of Staphylococcus aureus colonization and skin abscesses on formation of human anti-αGal antibodies. Medical Microbiology and Immunology, 214(1), Artikel 23. https://doi.org/10.1007/s00430-025-00833-3

Granhøj, J., Lildballe, D. L., Pedersen, K. V., Tougaard, B. G., Sokol, M., Aagaard, M. M., Petersen, A. H., Kristensen, T., Djursby, M., Birn, H. & Rasmussen, M. (2025). MUC1-associated autosomal dominant tubulointerstitial kidney disease: prevalence in kidney failure of undetermined aetiology and clinical insights from Danish families. Clinical Kidney Journal, 18(1), Artikel sfae355. https://doi.org/10.1093/ckj/sfae355

Geday, S., Prior, A., Pedersen, H. S., de Thurah, A., Næser, E. & Troldborg, A. (2025). Increased healthcare utilisation in the 5 years preceding systemic lupus erythematosus diagnosis: a Danish nationwide cohort study. Annals of the Rheumatic Diseases, 84(6), 992-1000. https://doi.org/10.1016/j.ard.2025.02.001

Nielsen, M. A., Bendix, M., Hvas, C. L., Deleuran, B., Reinert, L. S., Agnholt, J. & Dige, A. (2025). Increased mucosal and T-cell expression of 4-1BB and PD-1 are modulated by anti-TNFα treatment in Crohn’s disease. Scandinavian Journal of Gastroenterology, 60(7), 698-706. https://doi.org/10.1080/00365521.2025.2505622

Li, L., Coghill, D., Sjölander, A., Yao, H., Zhang, L., Kuja-Halkola, R., Brikell, I., Lichtenstein, P., D'onofrio, B. M., Larsson, H. & Chang, Z. (2025). Increased Prescribing of Attention-Deficit/Hyperactivity Disorder Medication and Real-World Outcomes Over Time. JAMA Psychiatry, Artikel 1281. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.1281

Soták, M., Clark, M. C., Suur, B. E. & Börgeson, E. (2025). Inflammation and resolution in obesity. Nature Reviews. Endocrinology, 21, 45-61. Artikel 3261. https://doi.org/10.1038/s41574-024-01047-y

Cong, Y., Verlhac, P., Green, B. B., de Vries-Idema, J., Strauss, L. M., Río-Bergé, C., Etzerodt, A., Nejsum, L. N., Huckriede, A. L. W. & Reggiori, F. (2025). Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry. Science Advances, 11(24), Artikel eadu7602. https://doi.org/10.1126/sciadv.adu7602

Fejerskov, O. (2025). Initiation and Progression of Dental Caries in Dental Hard Tissues. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 199-231). Wiley-Blackwell.

Sun, B., Ni, M., Li, Y., Song, Z., Wang, H., Zhu, H. L., Wei, J., Belke, D., Cai, S., Guo, W., Yao, J., Tian, S., Estillore, J. P., Wang, R., Søndergaard, M. T., Brohus, M., Rohde, P. D., Mu, Y., Vallmitjana, A. ... Chen, S. R. W. (2025). Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. Circulation, 151(12), 847-862. https://doi.org/10.1161/CIRCULATIONAHA.124.070563

Shin, M., Crouse, J. J., Weger, M., McKenna, S., Wray, N. R., Scott, E. M., Hickie, I. B. & Gachon, F. (Accepteret/In press). Insulin resistance as an early marker in youth with mood disorders. Nature Mental Health. https://doi.org/10.1038/s44220-025-00472-w

Gao, Z. & Bak, R. O. (2025). Integration of large genetic payloads using prime editing and site-specific integrases. Nature Protocols, 20(6), 1391-1392. https://doi.org/10.1038/s41596-024-01094-9

Ferro Desideri, L., Kojima, K., Eldridge, N., Zysset-Burri, D. C., Ørskov, M., Vorum, H., Honoré, B., Zinkernagel, M. S. & Cehofski, L. J. (2025). Integration of proteomics and artificial intelligence-driven OCT biomarker analysis in central retinal vein occlusion. Experimental Eye Research, 258, Artikel 110462. https://doi.org/10.1016/j.exer.2025.110462

Vallentin, M. F., Granfeldt, A., Klitgaard, T. L., Mikkelsen, S., Folke, F., Christensen, H. C., Povlsen, A. L., Petersen, A. H., Winther, S., Frilund, L. W., Meilandt, C., Holmberg, M. J., Winther, K. B., Bach, A., Dissing, T. H., Terkelsen, C. J., Christensen, S., Kirkegaard Rasmussen, L., Mortensen, L. R. ... Andersen, L. W. (2025). Intraosseous or Intravenous Vascular Access for Out-of-Hospital Cardiac Arrest. The New England Journal of Medicine, 392(4), 349-360. https://doi.org/10.1056/NEJMoa2407616

Pedersen, S. F. & Boedtkjer, E. (2025). Introducing a special issue: Acid–base regulation and sensing in health and disease. Acta Physiologica, 241(4), Artikel e70021. https://doi.org/10.1111/apha.70021, https://doi.org/10.1111/apha.70021

Bang Madsen, K., Larsson, H., Skoglund, C., Liu, X., Munk-Olsen, T., Bergink, V., Newcorn, J. H., Cortese, S., Lichtenstein, P., Kuja-Halkola, R., Chang, Z., D'Onofrio, B., Hove Thomsen, P., Klungsøyr, K., Brikell, I. & Garcia-Argibay, M. (2025). In utero exposure to methylphenidate, amphetamines and atomoxetine and offspring neurodevelopmental disorders - a population-based cohort study and meta-analysis. Molecular Psychiatry, 30(9), 3885-3894. Artikel 450. Advance online publication. https://doi.org/10.1038/s41380-025-02968-4

Haysen, S. R., Nielsen, A. L.-L., Qvist, P. & Kragstrup, T. W. (2025). Investigating associations between JAK inhibition and venous thromboembolism by systematic mining of large-scale datasets. Inflammopharmacology, 33(3), 1425-1434. Artikel e1004219. https://doi.org/10.1007/s10787-025-01677-2

Antonsen, K. W., Jensen, A. G., Sorensen, B., Etzerodt, A., Moestrup, S. K. & Møller, H. J. (2025). In vitro ovarian tumor-conditioned CD163+ human macrophages retain phagocytic response to CD47 blockade. Cellular Immunology, 409-410, Artikel 104932. https://doi.org/10.1016/j.cellimm.2025.104932

Kang, J., Kanugovi, A., Stella, M. P. J., Frimand, Z., Farup, J., Urtasun, A., Liu, S., Clausen, A.-S., Ishak, H., Bui, S., Kim, S., Ezran, C., Botvinnik, O., Porpiglia, E., Krasnow, M. A., de Morree, A. & Rando, T. A. (2025). In vivo self-renewal and expansion of quiescent stem cells from a non-human primate. Nature Communications, 16(1), Artikel 5370. https://doi.org/10.1038/s41467-025-58897-x

Blanco, G., Xue, J., Thomas, L., Dominguez Rieg, J. A., Sun, D., Assmus, A., Fenton, R. A. & Rieg, T. (2025). Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus. Acta Physiologica, 241(4), Artikel e70029. https://doi.org/10.1111/apha.70029

Hummelgaard, S., Hvid, H., Birn, H., Glerup, S., Tom, N., Bilgin, M., Kirchhoff, J. E. & Weyer, K. (2025). Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats. American journal of physiology. Renal physiology, 328(1), F48-F67. https://doi.org/10.1152/ajprenal.00065.2024

Hørsdal, O. K., Ellegaard, M. S., Larsen, A. M., Guldbrandsen, H. Ø., Moeslund, N., Eifer Møller, J., Helgestad, O. K. L., Ravn, H. B., Wiggers, H., Nielsen, B. R. R., Gopalasingam, N. & Berg-Hansen, K. (2025). Lactate infusion improves cardiac function in a porcine model of ischemic cardiogenic shock. Critical Care, 29(1), Artikel 113. https://doi.org/10.1186/s13054-025-05346-2

Homilius, C., Seefeldt, J. M., Hansen, J., Nielsen, B. R. R., de Paoli, F. V. & Boedtkjer, E. (2025). Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy. Acta Physiologica, 241(5), Artikel e70037. https://doi.org/10.1111/apha.70037

Li, C., Lv, W., He, Z., Pan, X., Zeng, Y., Mulder, J., Sjöstedt, E., Huang, Z., Liu, W., Xu, L., Eisenberg, E., Lin, L., Hansen, J. B., Huang, J. & Luo, Y. (2025). Landscape of A-I RNA editing in mouse, pig, macaque, and human brains. Nucleic Acids Research, 53(11), Artikel gkaf534. https://doi.org/10.1093/nar/gkaf534

Ferapontov, A., Mellemkjær, A., Mcgettrick, H., Vorup-Jensen, T., Kragstrup, T. W. & Juul-Madsen, K. (2025). Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation. Journal of Translational Autoimmunity, 10, Artikel 100266. https://doi.org/10.1016/j.jtauto.2025.100266

Zein, L., Dietrich, M., Balta, D., Bader, V., Scheuer, C., Zellner, S., Weinelt, N., Vandrey, J., Mari, M. C., Behrends, C., Zunke, F., Winklhofer, K. F. & Van Wijk, S. J. L. (2025). Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival. Autophagy, 21(5), 1075-1095. https://doi.org/10.1080/15548627.2024.2443945

Espejo, M. S., Orlowski, A., Sørensen, T. M., Matchkov, V., Ernesto, E. A. & Boedtkjer, E. (2025). Loss of Na⁺,HCO₃^–-cotransporter NBCn1 inhibits net acid extrusion in the atria and causes hypertension-associated cardiac hypertrophy. Acta Physiologica, 241(8), Artikel e70078. https://doi.org/10.1111/apha.70078

Lou, S., Ryberg, A., Becher, N., Lund, I. C. B. & Vogel, I. (2025). Making Sense of a Prenatal Detection of Trisomy 16 Mosaicism in the Placenta: A Qualitative Study of Pregnant Women's Decision Making. Prenatal Diagnosis, 45(5), 608-617. https://doi.org/10.1002/pd.6751

Zeng, Y., Lv, W., Tao, H., Li, C., Jiang, S., Liang, Y., Chen, C., Yu, T., Li, Y., Wu, S., Cui, X., Liang, N., Wang, P., Xu, H., Dong, J., Teng, H., Chen, K., Mu, K., Fan, T. ... Han, P. (2025). Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneity. iScience, 28(1), 111510. Artikel 111510. https://doi.org/10.1016/j.isci.2024.111510

iPSYCH-MINERvA Group (2025). Maternal asthma and newborn DNA methylation. Clinical Epigenetics, 17(1), Artikel 79. https://doi.org/10.1186/s13148-025-01858-4

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