Peer-reviewed publikationer

Peer-reviewed publications

Månsson, C. T., Nielsen, A. L. & Sorensen, B. (2025). Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA. Molecular Oncology. Advance online publication. https://doi.org/10.1002/1878-0261.70145

Bjerre, L. B., Chalmers, S. B. & Davis, F. M. (2025). Little women: the relevance and reliance on mouse models for mammary gland research and next steps for translation. Journal of Mammary Gland Biology and Neoplasia, 30(1), Artikel 16. https://doi.org/10.1007/s10911-025-09590-8

Espejo, M. S., Orlowski, A., Sørensen, T. M., Matchkov, V., Ernesto, E. A. & Boedtkjer, E. (2025). Loss of Na⁺,HCO₃^–-cotransporter NBCn1 inhibits net acid extrusion in the atria and causes hypertension-associated cardiac hypertrophy. Acta Physiologica, 241(8), Artikel e70078. https://doi.org/10.1111/apha.70078

Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W., Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025). LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling. Pigment Cell & Melanoma Research, 38(5), Artikel e70053. https://doi.org/10.1111/pcmr.70053

Delaunay, K., Picard, E., Lassiaz, P., Jonet, L., Cannaya, V., Ruiz-Moreno, J. M., Kojima, K., Vorum, H., Honoré, B., Medrano, J. R., Cehofski, L. J., Pussard, E., Kozyraki, R., Torriglia, A., Cases, O. & Behar-Cohen, F. (2025). LRP2 is a potential molecular target for nonsyndromic pathological myopia. JCI Insight, 10(15), Artikel e192929. https://doi.org/10.1172/jci.insight.192929

Lou, S., Ryberg, A., Becher, N., Lund, I. C. B. & Vogel, I. (2025). Making Sense of a Prenatal Detection of Trisomy 16 Mosaicism in the Placenta: A Qualitative Study of Pregnant Women's Decision Making. Prenatal Diagnosis, 45(5), 608-617. https://doi.org/10.1002/pd.6751

Albarrán-Juárez, J., Markov, A., Jensen, A. L., Møller, P. L., Uryga, A. K., Djordjevic, D., Hansen, J., Jensen, L. F., Sharysh, D., Pyke, C., Moreno, J., Borghetti, G., Bachmann, J., Herum, K., Røge, L. M., Traylor, M., Nyberg, M., Nyegaard, M. & Bentzon, J. F. (2025). Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease. iScience, 28(11), Artikel 113698. https://doi.org/10.1016/j.isci.2025.113698

Zeng, Y., Lv, W., Tao, H., Li, C., Jiang, S., Liang, Y., Chen, C., Yu, T., Li, Y., Wu, S., Cui, X., Liang, N., Wang, P., Xu, H., Dong, J., Teng, H., Chen, K., Mu, K., Fan, T. ... Han, P. (2025). Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneity. iScience, 28(1), 111510. Artikel 111510. https://doi.org/10.1016/j.isci.2024.111510

iPSYCH-MINERvA Group (2025). Maternal asthma and newborn DNA methylation. Clinical Epigenetics, 17(1), Artikel 79. https://doi.org/10.1186/s13148-025-01858-4

Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Artikel 620. https://doi.org/10.1186/s12916-025-04487-z

Thunbo, M. Ø., Vendelbo, J. H., Larsen, A., Witte, D. R. & Pedersen, L. H. (2025). Maternal Demographic Patterns in Medication use During Pregnancy: A Nationwide Register Study. Basic & Clinical Pharmacology & Toxicology, 136(4), Artikel e70020. https://doi.org/10.1111/bcpt.70020

Kücükyildiz, A. S., Thunbo, M. Ø., Swan, C. Z., Burgner, D. P., Miller, J., Ovesen, T. & Pedersen, L. H. (2025). Maternal Exposure to Medications and the Risk of Congenital and Early-Onset Hearing Loss in Children: A Systematic Review and a Meta-Analysis. Basic & Clinical Pharmacology & Toxicology, 137(3), Artikel e70090. https://doi.org/10.1111/bcpt.70090

Fonager, S. V., Winther, G., Weber, Y. C. L., Wittenborn, T. R., Kastberg, K. S., Terczyńska-Dyla, E., Jensen, L., Hansen, L. A., Carroll, M. C., Luo, Y., Lin, L. & Degn, S. E. (2025). Maternal imprinting of autoreactivity in a murine model of systemic lupus erythematosus. Brain, Behavior, and Immunity, 129, 921-934. https://doi.org/10.1016/j.bbi.2025.07.025

Khan, S. Z., Mamsen, L. S., Ernst, E., Budtz-Jørgensen, E., Andersen, C. Y. & Tommerup, N. (2025). Maternal smoking affects human fetal X-inactivation. Reproductive Toxicology, 137, Artikel 109010. https://doi.org/10.1016/j.reprotox.2025.109010

Lohrmann, F., Efstratiou, A., Sørensen, U. B. S., Creti, R., Decheva, A., Křížová, P., Kozáková, J., Rodriguez-Granger, J., De La Rosa Fraile, M., Margarit, I., Rinaudo, D., Maione, D., Telford, J., Orefici, G., Kilian, M., Afshar, B., Melin, P., Berner, R., Hufnagel, M. ... on behalf of DEVANI Study Group (2025). Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study. Infection, 53(1), 373-381. https://doi.org/10.1007/s15010-024-02380-0

Olsen, N. E., Mariager, C. Ø., Arildsen, M. M., Nielsen, S., Vendelbo, M. H., Pedersen, M., Laustsen, C., Ringgaard, S., Tolbod, L. P. & Buus, N. H. (2025). Measurement of renal cortex perfusion: A direct comparison of arterial spin labelling magnetic resonance imaging and [¹⁵O]H₂O positron emission tomography. Magnetic Resonance in Medicine, 94(6), 2537-2549. https://doi.org/10.1002/mrm.30638

Johnsen, L. Ø., Friis, K. A., Møller-Madsen, M. K. & Damkier, H. H. (2025). Mechanisms of cerebrospinal fluid secretion by the choroid plexus epithelium: Application to various intracranial pathologies. Clinical Anatomy, 38(1), 63-74. https://doi.org/10.1002/ca.24199

Dittrich, A., Andersson, S. A., Busk, M., Hansen, K., Foldager, C. B., Palmfeldt, J., Andersen, A., Pedersen, M., Vendelbo, M., Nielsen, K. L. & Lauridsen, H. (2025). Metabolic changes during cardiac regeneration in the axolotl. Developmental Dynamics. Advance online publication. https://doi.org/10.1002/dvdy.70020

Madsen, K. S., Henriksen, M., Døssing, A., Poulsen, A. S., Oscar, R., Kragstrup, T., Ellegaard, K., Knop, F. K., Boesen, M., Hunter, D. J., Christensen, R. & Bliddal, H. (2025). Metformin treatment for patients with hand osteoarthritis: protocol for the multicentre, randomised, placebo-controlled METRO trial. BMJ Open, 15(3), Artikel e093831. Advance online publication. https://doi.org/10.1136/bmjopen-2024-093831

Rodriguez-Palomo, A., Didziokas, M., Jacobsen, M. S. B., Christensen, T. E. K., Kantor, I., Jørgensen, M. R. V., Almtoft, K. P., Thomsen, J. S., Herrel, A., Williams, C. & Birkedal, H. (2025). Micro and Nanostructural Diversity of Lizard Osteoderm Capping Tissue in Relation to Mechanical Performance. Advanced Functional Materials, Artikel e26169. Advance online publication. https://doi.org/10.1002/adfm.202526169

Sakai, Y., Behrends, C., Cuervo, A. M., Debnath, J., Izumi, M., Jenny, A., Molinari, M., Nakamura, S., Oku, M., Otegui, M. S., Santambrogio, L., Shen, H.-M., Taguchi, T., Thumm, M., Ushimaru, T., Xie, Z. & Reggiori, F. (2025). Microautophagy: definition, classification, and the complexity of the underlying mechanisms. Autophagy. Advance online publication. https://doi.org/10.1080/15548627.2025.2559687

Xu, J., Verma, E., Sanchez, J., Gharaie, S., Jeong, S., Patel, S. K., Gooya, M., Rosa, X. D. L., Gupta, K., Rinschen, M. M., Rabb, H. & Pluznick, J. L. (2025). Microbes and Glomerular Filtration Rate in Health and CKD in Mice. Journal of the American Society of Nephrology. Advance online publication. https://doi.org/10.1681/ASN.0000000814

Bloom, P. P., Garrett, W. S., Penniston, K. L., Winkler, M.-K. H., Hazen, S. L., Agudelo, J., Suryavanshi, M., Babiker, A., Dodd, D., Fischbach, M. A., Huang, K. C., Huttenhower, C., Joe, B., Kalantar-Zadeh, K., Knight, R., Miller, A. W., Rabb, H., Srivastava, A., Tang, W. H. W. ... Pluznick, J. L. (2025). Microbiota and kidney disease: the road ahead. Nature Reviews. Nephrology, 21(10), 702-716. https://doi.org/10.1038/s41581-025-00988-5

Haidari, R., Fowler, W. J., Robinson, S. D., Johnson, R. T. & Warren, D. T. (2025). Microvascular endothelial cells display organ-specific responses to extracellular matrix stiffness. Current Research in Physiology, 8, Artikel 100140. https://doi.org/10.1016/j.crphys.2025.100140

Pozzo, E., Yedigaryan, L., Giarratana, N., Wang, C. C., Garrido, G. M., Degreef, E., Marini, V., Rinaldi, G., van der Veer, B. K., Sassi, G., Eelen, G., Planque, M., Fanzani, A., Koh, K. P., Carmeliet, P., Yustein, J. T., Fendt, S. M., Uyttebroeck, A. & Sampaolesi, M. (2025). miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma. Cell Reports, 44(1), Artikel 115171. https://doi.org/10.1016/j.celrep.2024.115171

Hjelholt, A. J., Gholipourshahraki, T., Bai, Z., Shrestha, M., Kjolby, M., Sørensen, P. & Rohde, P. D. (2025). mLeveraging genetic correlations to prioritize drug groups for repurposing in type 2 diabetes. Pharmacogenomics Journal, 25(6), Artikel 33. https://doi.org/10.1038/s41397-025-00392-z

Silva, N. R., Arjmand, S., Domingos, L. B., Chaves-Filho, A. M., Mottin, M., Real, C. C., Waszkiewicz, A. L., Gobira, P. H., Ferraro, A. N., Landau, A. M., Andrade, C. H., Müller, H. K., Wegener, G. & Joca, S. R. L. (2025). Modulation of the endocannabinoid system by (S)-ketamine in an animal model of depression. Pharmacological Research, 211, 107545. Artikel 107545. https://doi.org/10.1016/j.phrs.2024.107545

Larsen, M. L., Nørgaard, L., Linge, P., Larsen, J. B., Langkilde, H. Z., Hauge, E. M., Thiel, S., Voss, A., Bengtsson, A. & Troldborg, A. (2025). Molecular mechanisms underlying thrombosis in systemic lupus erythematosus: A Systematic review. Seminars in Arthritis and Rheumatism, 72, Artikel 152707. https://doi.org/10.1016/j.semarthrit.2025.152707

Rydder, P. M., Andreasen, L., Thomsen, S. H., Jensen, U. B., Becher, N., Dunø, M. & Vogel, I. (2025). Mosaic STS gene deletions in chorionic villus samples are often confined to the placenta, and they differ in size from STS gene deletions in patients with X-linked Ichthyosis. Placenta, 165, 16-22. https://doi.org/10.1016/j.placenta.2025.03.016

Ezran, C., Liu, S., Chang, S., Ming, J., Guethlein, L. A., Wang, M. F. Z., Dehghannasiri, R., Olivieri, J., Frank, H. K., Tarashansky, A., Koh, W., Jing, Q., Botvinnik, O., Antony, J., Pisco, A. O., Karkanias, J., Yang, C., Ferrell, J. E., Boyd, S. D. ... Tabula Microcebus Consortium (2025). Mouse lemur cell atlas informs primate genes, physiology and disease. Nature, 644(8075), 185-196. https://doi.org/10.1038/s41586-025-09114-8

Holmberg, A., Pol-Fuster, J., Kuja-Halkola, R., Larsson, H., Lichtenstein, P., Chang, Z., D'Onofrio, B. M., Brikell, I., Sidorchuk, A., Isomura, K., Crowley, J. J., Martinsson, L., Rück, C., Mataix-Cols, D. & Fernández De La Cruz, L. (2025). Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders. BMJ Mental Health, 28(1), Artikel e301323. https://doi.org/10.1136/bmjment-2024-301323

Rovsing, A. B., Green, K., Jensen, L., Nielsen, I. H., Mikkelsen, J. G. & Degn, S. E. (2025). Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments. Scandinavian Journal of Immunology, 102(2), Artikel e70043. https://doi.org/10.1111/sji.70043

Corydon, T. J. & Bek, T. (2025). Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration. Progress in Retinal and Eye Research, 104, Artikel 101323. https://doi.org/10.1016/j.preteyeres.2024.101323

Girault, V., Stukalov, A., Carter-Timofte, M. E., Hertzog, J., Verin, M., Austen, K., Haas, D. A., Oubraham, L., Piras, A., Maidl, S., Öllinger, R., Rad, R., Protzer, U., Kaufer, B. B., Lebbink, R. J., Rehwinkel, J., Mogensen, T. H. & Pichlmair, A. (2025). Multi-proteomic profiling of the varicella-zoster virus–host interface reveals host susceptibilities to severe infection. Nature Microbiology, 10(8), 2048-2072. https://doi.org/10.1038/s41564-025-02068-7

Boonkaew, S., Teodori, L., Vendelbo, M. H., Kjems, J. & Ferapontova, E. E. (2025). Nanobodies' duo facilitates ultrasensitive serum HER-2/neu immunoassays via enhanced avidity interactions. Analytica Chimica Acta, 1335, Artikel 343472. https://doi.org/10.1016/j.aca.2024.343472

Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J., Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025). Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake. npj biosensing, 2, Artikel 23. https://doi.org/10.1038/s44328-025-00042-1

Jensen, E. G., Jakobsen, T. S., Schnabolk, G., Wilson, K., Rask-Pedersen, M., Jensen, N., Andersen, G. R., Thiel, S., Aagaard, L., Rohrer, B., Askou, A. L. & Corydon, T. J. (2025). Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice. Molecular Therapy Methods and Clinical Development, 33(4), Artikel 101620. https://doi.org/10.1016/j.omtm.2025.101620

Joca, S. (2025). Neurodegenerative disorders: Advances in neurobiology and new treatment perspectives. Basic and Clinical Pharmacology and Toxicology, 136(1), Artikel e14098. https://doi.org/10.1111/bcpt.14098

Grønnebæk, T. S., Haahr-Lillevang, H., Skov, M., Kelly, K., Kerr, N. R., Viteri, J. A., Jaworek, A., Bartlett, A., Bold, J., Hutchison, J., Quiroz, J., Tankisi, H., Pedersen, T. H., Andersen, H. & Arnold, W. D. (2025). Neuromuscular transmission deficits in patients with CMT and ClC-1 inhibition in CMT animal models. Annals of Clinical and Translational Neurology, 12(2), 320-331. https://doi.org/10.1002/acn3.52252, https://doi.org/10.1002/acn3.52252

Santi, M. M., Genovese, E., Schou, T. M., da Silva, M., Erhardt, S., Schwieler, L., Weidenfors, J. A., Marino, G., Paludan, S. R., Joca, S., Wegener, G., Reinert, L. & Bay-Richter, C. (2025). Neuropsychiatric- and cognitive post-acute sequelae of SARS-CoV-2 infection - evidence from K18-hACE C57BL/6 J mice. The international journal of neuropsychopharmacology, 28(10), Artikel pyaf072. https://doi.org/10.1093/ijnp/pyaf072

Voloudakis, G., Therrien, K., Tomasi, S., Rajagopal, V. M., Choi, S. W., Demontis, D., Fullard, J. F., Børglum, A. D., O’Reilly, P. F., Hoffman, G. E. & Roussos, P. (2025). Neuropsychiatric polygenic scores are weak predictors of professional categories. Nature Human Behaviour, 9(3), 595-608. Artikel 2457. https://doi.org/10.1038/s41562-024-02074-5

Wehland, M., Corydon, T. J., González-Torres, L. F., Abdelfattah, F., Sahana, J., Schulz, H., Mushunuri, A., Burenkova, H., Wuest, S. L., Krüger, M., Kraus, A. & Grimm, D. (2025). New Knowledge About Tissue Engineering Under Microgravity Conditions in Space and on Earth. International Journal of Molecular Sciences , 27(1), Artikel 341. https://doi.org/10.3390/ijms27010341

Aymerich, N., Bucheli, O. T. M., Portmann, K., Schlotheuber, L. J., Sigvaldadóttir, I., Baudry, J. & Eyer, K. (2025). Non-conjugated TLR agonists increase the quantity of antibodies but not their quality in a murine immunization model. Vaccine, 62, Artikel 127518. https://doi.org/10.1016/j.vaccine.2025.127518

Bedei, I., Bruder, J., Lund, I. C. B., Thomsen, S. H., Vogel, I., Maciel-Guerra, A. T., Alvarez-Nava, F., Crenshaw, M. L., Axt-Fliedner, R., Gravholt, C. H. & Skakkebæk, A. (2025). Non-Invasive Prenatal Testing by Cell-Free DNA (cfNIPT) for Detecting Turner Syndrome With Mosaicism and Structural Variants—Prenatal Findings and Postnatal Outcomes. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, 199(2), 124-133. https://doi.org/10.1002/ajmg.c.32136

Dmytriw, A. A., Butt, W., Blanc, R., Piotin, M., DeVries, J., Levrier, O., Papagiannaki, C., Buhk, J.-H., Mikkelsen, R., Al Raaisi, A., Redjem, H., Guedin, P., Milot, G., Chau, Y., Chow, M., Navasa, J. M., Naggara, O., Sedat, J., Desal, H.-A. ... Sorensen, L. (2025). Novel Delivery System Significantly Improves Technical Success and Safety of the Endovascular Clip System (eCLIPs) While Maintaining Efficacy for the Treatment of Wide-Necked Bifurcation Aneurysms: A Prospective, Multisite Registry. Neurosurgery, 97(4), 963-970. Artikel 10.1227/neu.0000000000003666. https://doi.org/10.1227/neu.0000000000003666

Actis Dato, V., Fujita, K. & Lange, S. (2025). Novel links of ATG4 proteases to cytoskeletal adapters of the obscurin protein family. Autophagy, 21(12), 3433-3435. https://doi.org/10.1080/15548627.2025.2572530

Hasan, S. S., John, D., Rudnicki, M., AlZaim, I., Eberhard, D., Moll, I., Taylor, J., Klein, C., von Heesen, M., Conradi, L. C., Adams, R. H., Lammert, E., Kalucka, J., Ruhrberg, C., Dimmeler, S. & Fischer, A. (2025). Obesity drives depot-specific vascular remodeling in male white adipose tissue. Nature Communications, 16(1), Artikel 5392. https://doi.org/10.1038/s41467-025-60910-2

Pioner, J. M., Pierantozzi, E., Coppini, R., Rubino, E. M., Biasci, V., Vitale, G., Laurino, A., Santini, L., Scardigli, M., Randazzo, D., Olianti, C., Serano, M., Rossi, D., Tesi, C., Cerbai, E., Lange, S., Reggiani, C., Sacconi, L., Poggesi, C. ... Sorrentino, V. (2025). Obscurin deficiency leads to compensated dilated cardiomyopathy and increased arrhythmias. Journal of General Physiology, 157(4), Artikel e202413696. https://doi.org/10.1085/jgp.202413696

Gribsholt, S. B., Horváth-Puhó, E., Elser, H., Laugesen, K., Skajaa, N., Fuglsang, C. H., Henderson, V. & Sørensen, H. T. (2025). Obstructive sleep apnoea and risk of dementia: a Danish population-based cohort study. BMJ Neurology Open, 7(2), Artikel e001174. https://doi.org/10.1136/bmjno-2025-001174

Jensen, S. K., Bertelsen, M., Vestergaard, S. V., Nørgaard, M., Thomsen, R. W., Birn, H., Heide-Jørgensen, U. & Christiansen, C. F. (2025). Occurrence and prognosis of chronic kidney disease in Denmark-a nationwide population-based cohort study. Clinical Kidney Journal, 18(6), Artikel sfaf147. https://doi.org/10.1093/ckj/sfaf147

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Revideret 21.08.2025