Peer-reviewed publikationer

Peer-reviewed publications

Larsen, M. L., Voss, A., Tandrup Holst Nielsen, C., Hauge, E. M., Faurschou, M. & Troldborg, A. (2025). Highlighting individual patient data related to chimeric antigen receptor T-cell therapy in refractory autoimmune rheumatic diseases. Scandinavian Journal of Rheumatology, 54(3), 219-224. https://doi.org/10.1080/03009742.2024.2421621

Schlotheuber, L. J., Vollenweider, M., Gutjahr, S., Hungerland, T., Danis, R., Ormaniec, W., Linder, A., Boeva, V., Lüchtefeld, L. & Eyer, K. (2025). High-resolution time-lapse imaging of droplet-cell dynamics via optimal transport and contrastive learning. Lab on a Chip, 25(22), 6004-6017. https://doi.org/10.1039/d5lc00351b

Cong, Y. & Reggiori, F. (2025). Hijacking a cellular highway: non-lipidated LC3 proteins and PCNT (pericentrin) drive influenza a virus uncoating. Autophagy. Advance online publication. https://doi.org/10.1080/15548627.2025.2572527

Hu, Y., Chourpiliadis, C., Ingre, C., Ahlqvist, V. H., Sun, J., Song, H., Pawitan, Y., Piehl, F. & Fang, F. (2025). Hospital-treated infections and the risk and prognosis of amyotrophic lateral sclerosis: A population-based study. Journal of Internal Medicine, 298(4), 349-360. https://doi.org/10.1111/joim.70008

Kanai, R., Tsunekawa, N., Cornelius, F., Vilsen, B. & Toyoshima, C. (2025). How palytoxin transforms the Na⁺,K⁺ pump into a cation channel. Proceedings of the National Academy of Sciences of the United States of America, 122(38), Artikel e2506450122. https://doi.org/10.1073/pnas.2506450122

Kildegaard, T. H., Sabroe, D., Wang, M. & Høy, K. (2025). How to select a treatment method for patients with potentially unstable metastatic vertebrae (spinal instability neoplastic score 7-12): a systematic review. Asian Spine Journal. Advance online publication. https://doi.org/10.31616/asj.2025.0078

Al-Rousan, T., Naja, W., Wejse, C. M., Kaki, D., Aoun, M., Lange, S., Alshawabkeh, L., Alhamad, R., Kadri, N. & Eiset, A. H. (2025). Hypertension in Syrian refugees: prevalence, awareness, and access to care in Denmark and Lebanon. Frontiers in Public Health, 13, Artikel 1486806. https://doi.org/10.3389/fpubh.2025.1486806

Staehr, C., Hinkley, V., Matchkov, V. V., Rajanathan, R., Hansen, L. M. B., Eiby, Y., Luque, N., Wright, I., Bjorkman, S. T., Miller, S. M., Grimley, R. S., Dettrick, A., Chand, K., Nguyen, H. L., Jones, N. M., Murphy, T. V. & Sandow, S. L. (2025). Hypoxia and ischemic stroke modify cerebrovascular tone by upregulating endothelial BK(Ca) channels—Lessons from rat, pig, mouse, and human. Acta Physiologica (Print), 241(4), Artikel e70030. https://doi.org/10.1111/apha.70030

Jacobsen, V., Pan, V. A., Tran, L. T., Vohradsky, J., Bønnelykke, J., Schmidt Herø, C., Johansen, J. G., Tobias Frederiksen, A., Singers Sørensen, B., Busk, M., Sauerwein, W. A. G., Rosenfeld, A. B. & Bassler, N. (2025). In-vitro and microdosimetric study of proton boron capture therapy and neutron capture enhanced proton therapy. Physics in Medicine and Biology, 70(5). https://doi.org/10.1088/1361-6560/adb199

Gugu, M., Acharya, S., Pira, D., Poletti, S., di Flora, A., Saksida, T., Pilipenko, V., Romero-Ramos, M., Marino, F., Muñoz Delgado, L., Nikolovski, N., Gursoy Ozdemir, Y., Lawson, D., Comi, C. & Figueira, I. (2025). IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET. Open Research Europe, 4, Artikel 119. https://doi.org/10.12688/openreseurope.17547.2

Lewash, S. A., McKenney, V. R., Wuebben, C., Ludwig, J., Hosni, R., Radzey, D., Toma, M. I., Bartok, E., Schlee, M., Zillinger, T., Heckel, A. & Hartmann, G. (2025). Immunoengineering of a Photocaged 5´-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer. Angewandte Chemie - International Edition, 64(21), Artikel e202423321. https://doi.org/10.1002/anie.202423321

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Artikel e1004092. https://doi.org/10.1038/s41380-025-03032-x

Laursen, D. R. T., Broager, M. I., Damkjær, M. W., Eiset, A. H., Elkjær, M., Faltinsen, E., MacLean-Nyegaard, I. R., Nejstgaard, C. H., Paludan-Müller, A. S., Petersen, L. A. B., Vestergaard, S. V. & Hróbjartsson, A. (2025). Impact of active placebo controls on estimated drug effects in randomized trials: a meta-epidemiological study. Journal of Clinical Epidemiology, 188, Artikel 111998. https://doi.org/10.1016/j.jclinepi.2025.111998

El-Awaisi, J., Kavanagh, D., Heising, S., Schiessl, I. M., Cleary, S. J., Hodson, D. J. & Kalia, N. (2025). Impact of chronic hyperglycaemia on the coronary microcirculation – benefits of targeting IL-36 and diet reversal. Basic Research in Cardiology, 120(3), 509-526. Artikel 660698. https://doi.org/10.1007/s00395-025-01107-y

Schreiber, K., Graversgaard, C., Parodis, I., Agmon-Levin, N., Aguilera, S., Antovic, A., Bertsias, G. K., Bini, I., Bobirca, A., Capela, S., Cervera, R., Costedoat-Chalumeau, N., Dolhain, R., Etomi, O., Flint, J., Fonseca, J. E., Fritsch-Stork, R., Förger, F., Giles, I. ... Andreoli, L. (2025). Impact of conflicting information on the use of antirheumatic drugs in pregnancy and breastfeeding: perspectives of healthcare providers from the global PRAISE survey. Therapeutic Advances in Musculoskeletal Disease, 17, Artikel 1759720X251350087. https://doi.org/10.1177/1759720X251350087

Andersen, J. W., Høgh, A., Lindholt, J. S., Søgaard, R., Støvring, H., Yderstræde, K. B., Sandbæk, A. & Dahl, M. (2025). Impact of population-based screening for diabetes and prediabetes among 67-year-olds using point-of-care Hba1c on healthcare ultilisation, results from the VISP cohort. Clinical epidemiology, 17, 75-85. https://doi.org/10.2147/CLEP.S487825

Bernth Jensen, J. M., Dinh, K. M., Hindhede, L., Erikstrup, L. T., Hansen, A. G., Hymøller, K. M., Ostrowski, S. R., Pedersen, O. B. V., Christiansen, S. H., Sørensen, U. B. S., Thiel, S. & Erikstrup, C. (2025). Impact of Staphylococcus aureus colonization and skin abscesses on formation of human anti-αGal antibodies. Medical Microbiology and Immunology, 214(1), Artikel 23. https://doi.org/10.1007/s00430-025-00833-3

Bohn, A. B., Wittenborn, T. & Petersen, C. C. (2025). Implementing the CytoFLEX nano in a Shared Resource Laboratory: Overcoming Challenges and Optimizing Performance for Small Particle Analysis. Abstract fra CYTO 2025: Annual Conference for International Society for Advancement in Cytometry, Denver, Colorado, USA.

Granhøj, J., Lildballe, D. L., Pedersen, K. V., Tougaard, B. G., Sokol, M., Aagaard, M. M., Petersen, A. H., Kristensen, T., Djursby, M., Birn, H. & Rasmussen, M. (2025). MUC1-associated autosomal dominant tubulointerstitial kidney disease: prevalence in kidney failure of undetermined aetiology and clinical insights from Danish families. Clinical Kidney Journal, 18(1), Artikel sfae355. https://doi.org/10.1093/ckj/sfae355

Wang, X., Chang, Z., Molero, Y., Isomura, K., Fernández de la Cruz, L., Lichtenstein, P., Kuja-Halkola, R., D’Onofrio, B. M., Quinn, P. D., Larsson, H., Brikell, I., Hellner, C., Hasselström, J., Jayaram-Lindström, N., Mataix-Cols, D. & Sidorchuk, A. (2025). Incident benzodiazepine and Z-drug use and subsequent risk of alcohol- and drug-related problems: A nationwide matched cohort study with co-twin comparison. Journal of Psychopharmacology, Artikel 02698811251373069. Advance online publication. https://doi.org/10.1177/02698811251373069

Geday, S., Prior, A., Pedersen, H. S., de Thurah, A., Næser, E. & Troldborg, A. (2025). Increased healthcare utilisation in the 5 years preceding systemic lupus erythematosus diagnosis: a Danish nationwide cohort study. Annals of the Rheumatic Diseases, 84(6), 992-1000. https://doi.org/10.1016/j.ard.2025.02.001

Sagedal, S., Hovd, M., Åsberg, A., Mollnes, T. E., Klingenberg, O., Heldal, T. F., Witczak, B. J., Hejlesen, T. K., Troldborg, A. & Thiel, S. (2025). Increased levels of ficolin-1 and of C3dg are independently associated with high risk of infection in patients with chronic kidney disease: a prospective cohort study. Frontiers in Immunology, 16, Artikel 1645347. https://doi.org/10.3389/fimmu.2025.1645347

Nielsen, M. A., Bendix, M., Hvas, C. L., Deleuran, B., Reinert, L. S., Agnholt, J. & Dige, A. (2025). Increased mucosal and T-cell expression of 4-1BB and PD-1 are modulated by anti-TNFα treatment in Crohn’s disease. Scandinavian Journal of Gastroenterology, 60(7), 698-706. https://doi.org/10.1080/00365521.2025.2505622

Li, L., Coghill, D., Sjölander, A., Yao, H., Zhang, L., Kuja-Halkola, R., Brikell, I., Lichtenstein, P., D'onofrio, B. M., Larsson, H. & Chang, Z. (2025). Increased Prescribing of Attention-Deficit/Hyperactivity Disorder Medication and Real-World Outcomes Over Time. JAMA Psychiatry, Artikel 1281. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.1281

Soták, M., Clark, M. C., Suur, B. E. & Börgeson, E. (2025). Inflammation and resolution in obesity. Nature Reviews. Endocrinology, 21, 45-61. Artikel 3261. https://doi.org/10.1038/s41574-024-01047-y

Cong, Y., Verlhac, P., Green, B. B., de Vries-Idema, J., Strauss, L. M., Río-Bergé, C., Etzerodt, A., Nejsum, L. N., Huckriede, A. L. W. & Reggiori, F. (2025). Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry. Science Advances, 11(24), Artikel eadu7602. https://doi.org/10.1126/sciadv.adu7602

Fejerskov, O. (2025). Initiation and Progression of Dental Caries in Dental Hard Tissues. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 199-231). Wiley-Blackwell.

Sun, B., Ni, M., Li, Y., Song, Z., Wang, H., Zhu, H. L., Wei, J., Belke, D., Cai, S., Guo, W., Yao, J., Tian, S., Estillore, J. P., Wang, R., Søndergaard, M. T., Brohus, M., Rohde, P. D., Mu, Y., Vallmitjana, A. ... Chen, S. R. W. (2025). Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. Circulation, 151(12), 847-862. https://doi.org/10.1161/CIRCULATIONAHA.124.070563

Shin, M., Crouse, J. J., Weger, M., McKenna, S., Wray, N. R., Scott, E. M., Hickie, I. B. & Gachon, F. (2025). Insulin resistance as an early marker in youth with mood disorders. Nature Mental Health, 3(9), 969-971. https://doi.org/10.1038/s44220-025-00472-w

Gao, Z. & Bak, R. O. (2025). Integration of large genetic payloads using prime editing and site-specific integrases. Nature Protocols, 20(6), 1391-1392. https://doi.org/10.1038/s41596-024-01094-9

Ferro Desideri, L., Kojima, K., Eldridge, N., Zysset-Burri, D. C., Ørskov, M., Vorum, H., Honoré, B., Zinkernagel, M. S. & Cehofski, L. J. (2025). Integration of proteomics and artificial intelligence-driven OCT biomarker analysis in central retinal vein occlusion. Experimental Eye Research, 258, Artikel 110462. https://doi.org/10.1016/j.exer.2025.110462

Greda, A. K., Gomes, J. P., Schmidt-Krueger, V., Zurawska-Plaksej, E., Fritsche-Guenther, R., Rudolph, I.-M., Telugu, N. S., Cömert, C., Kirwan, J., Kunz, S., Rothe, M., Johannsen, M., Diecke, S., Bross, P. & Willnow, T. E. (2025). Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel. Nature Metabolism, 7(11), 2346–2365. https://doi.org/10.1038/s42255-025-01389-5

Dam, L. A. P., Lou, S., Skovslund Nielsen, E., Hansen Kallesøe, K., Søgaard Singh, H., Bonnert, M., Lalouni, M. & Ulrikka Rask, C. (2025). In this together: Parental experiences with internet-based cognitive behavioral therapy for childhood functional abdominal pain disorders. Journal of Health Psychology, Artikel 13591053251376193. Advance online publication. https://doi.org/10.1177/13591053251376193

Pedersen, S. F. & Boedtkjer, E. (2025). Introducing a special issue: Acid–base regulation and sensing in health and disease. Acta Physiologica, 241(4), Artikel e70021. https://doi.org/10.1111/apha.70021, https://doi.org/10.1111/apha.70021

Bang Madsen, K., Larsson, H., Skoglund, C., Liu, X., Munk-Olsen, T., Bergink, V., Newcorn, J. H., Cortese, S., Lichtenstein, P., Kuja-Halkola, R., Chang, Z., D'Onofrio, B., Hove Thomsen, P., Klungsøyr, K., Brikell, I. & Garcia-Argibay, M. (2025). In utero exposure to methylphenidate, amphetamines and atomoxetine and offspring neurodevelopmental disorders - a population-based cohort study and meta-analysis. Molecular Psychiatry, 30(9), 3885-3894. Artikel 450. https://doi.org/10.1038/s41380-025-02968-4

Haysen, S. R., Nielsen, A. L.-L., Qvist, P. & Kragstrup, T. W. (2025). Investigating associations between JAK inhibition and venous thromboembolism by systematic mining of large-scale datasets. Inflammopharmacology, 33(3), 1425-1434. Artikel e1004219. https://doi.org/10.1007/s10787-025-01677-2

Antonsen, K. W., Jensen, A. G., Sorensen, B., Etzerodt, A., Moestrup, S. K. & Møller, H. J. (2025). In vitro ovarian tumor-conditioned CD163+ human macrophages retain phagocytic response to CD47 blockade. Cellular Immunology, 409-410, Artikel 104932. https://doi.org/10.1016/j.cellimm.2025.104932

Kristensen, A. M., Bordoni, L., Nielsen, M. B., Faivre, A., Kidmose, H., Sardella, D., Shipman, K. E., Krogstrup, N. V., Størling, J., Birn, H., Enger, R. & Schiessl, I. M. (2025). In vivo expression of VCAM1 precedes nephron loss following kidney tubular necrosis. Science Advances, 11(43), 1-17. Artikel eadz5358. https://doi.org/10.1126/sciadv.adz5358

Kang, J., Kanugovi, A., Stella, M. P. J., Frimand, Z., Farup, J., Urtasun, A., Liu, S., Clausen, A.-S., Ishak, H., Bui, S., Kim, S., Ezran, C., Botvinnik, O., Porpiglia, E., Krasnow, M. A., de Morree, A. & Rando, T. A. (2025). In vivo self-renewal and expansion of quiescent stem cells from a non-human primate. Nature Communications, 16(1), Artikel 5370. https://doi.org/10.1038/s41467-025-58897-x

Lyhne, M. D., Gopalasingam, N., Berg-Hansen, K., Dragsbaek, S. J., Homilius, C., Seefeldt, J., Hansen, J. V., Kramer, A. D., Christensen, L. J., Ellegaard, M. S., Hørsdal, O. K., Overgaard, A., Larsen, A. M., Boedtkjer, E., Andersen, A. & Nielsen, R. (2025). Ketone bodies for hemodynamic support in acute pulmonary embolism: a randomized, blinded, controlled animal study. Intensive Care Medicine Experimental, 13(1), Artikel 133. https://doi.org/10.1186/s40635-025-00844-7

Ogurlu, B., van Furth, L. A., Zuo, Y., Hamelink, T. L., van Klinken, J. B., Pamplona, C. C., Bennedsgaard, S. S., van Leeuwen, L. L., Lantinga, V. A., Qi, H., Pool, M. B. F., Vendrell, I., Kessler, B. M., Fischer, R., Lin, L., Luo, Y., Jespersen, B., van Dijk, K. W., Bakker, B. M. ... Moers, C. (2025). Kidney Metabolism During Normothermic Machine Perfusion Differs Substantially From In Vivo Conditions. Transplantation. Advance online publication. https://doi.org/10.1097/TP.0000000000005586

Klæstrup, I. H., Reinert, L. S., Ferreira, S. A., Lauritsen, J., Toft, G. U., Gram, H., Jensen, P. H., Paludan, S. R. & Romero-Ramos, M. (2026). Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model. npj Parkinson's Disease , 12(1), Artikel 17. Advance online publication. https://doi.org/10.1038/s41531-025-01228-0

Blanco, G., Xue, J., Thomas, L., Dominguez Rieg, J. A., Sun, D., Assmus, A., Fenton, R. A. & Rieg, T. (2025). Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus. Acta Physiologica, 241(4), Artikel e70029. https://doi.org/10.1111/apha.70029

Hummelgaard, S., Hvid, H., Birn, H., Glerup, S., Tom, N., Bilgin, M., Kirchhoff, J. E. & Weyer, K. (2025). Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats. American journal of physiology. Renal physiology, 328(1), F48-F67. https://doi.org/10.1152/ajprenal.00065.2024

Hørsdal, O. K., Ellegaard, M. S., Larsen, A. M., Guldbrandsen, H. Ø., Moeslund, N., Eifer Møller, J., Helgestad, O. K. L., Ravn, H. B., Wiggers, H., Nielsen, B. R. R., Gopalasingam, N. & Berg-Hansen, K. (2025). Lactate infusion improves cardiac function in a porcine model of ischemic cardiogenic shock. Critical Care, 29(1), Artikel 113. https://doi.org/10.1186/s13054-025-05346-2

Homilius, C., Seefeldt, J. M., Hansen, J., Nielsen, B. R. R., de Paoli, F. V. & Boedtkjer, E. (2025). Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy. Acta Physiologica, 241(5), Artikel e70037. https://doi.org/10.1111/apha.70037

Li, C., Lv, W., He, Z., Pan, X., Zeng, Y., Mulder, J., Sjöstedt, E., Huang, Z., Liu, W., Xu, L., Eisenberg, E., Lin, L., Hansen, J. B., Huang, J. & Luo, Y. (2025). Landscape of A-I RNA editing in mouse, pig, macaque, and human brains. Nucleic Acids Research, 53(11), Artikel gkaf534. https://doi.org/10.1093/nar/gkaf534

Ferapontov, A., Mellemkjær, A., Mcgettrick, H., Vorup-Jensen, T., Kragstrup, T. W. & Juul-Madsen, K. (2025). Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation. Journal of Translational Autoimmunity, 10, Artikel 100266. https://doi.org/10.1016/j.jtauto.2025.100266

Lizarralde-Guerrero, M., Olagnier, D., Aranda, F., Maiuri, M. C., Kroemer, G. & Pol, J. G. (2025). Latest insights into oncolytic viro-immunotherapy with vesicular stomatitis virus. Seminars in Immunology, 80, Artikel 101996. https://doi.org/10.1016/j.smim.2025.101996

Zein, L., Dietrich, M., Balta, D., Bader, V., Scheuer, C., Zellner, S., Weinelt, N., Vandrey, J., Mari, M. C., Behrends, C., Zunke, F., Winklhofer, K. F. & Van Wijk, S. J. L. (2025). Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival. Autophagy, 21(5), 1075-1095. https://doi.org/10.1080/15548627.2024.2443945

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