Institut for Biomedicin - Medarbejderportal

Peer-reviewed publikationer

Peer-reviewed publications

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Brøns, N., Kaspersen, K. A., Bay, J. T., Dowsett, J., Erikstrup, C., Hjalgrim, H., Aagaard, B., Mikkelsen, C., Mikkelsen, S., Pedersen, O. B., Rostgaard, K., Schwinn, M., Sørensen, E., Rigas, A. S., Glenthøj, A. & Ostrowski, S. R. (2025). Iron deficiency and infection risk in Danish blood donors. Transfusion, 65(2), 286-296. https://doi.org/10.1111/trf.18105

Blanco, G., Xue, J., Thomas, L., Dominguez Rieg, J. A., Sun, D., Assmus, A., Fenton, R. A. & Rieg, T. (2025). Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus. Acta Physiologica (Print), 241(4), e70029. https://doi.org/10.1111/apha.70029

Hummelgaard, S., Hvid, H., Birn, H., Glerup, S., Tom, N., Bilgin, M., Kirchhoff, J. E. & Weyer, K. (2025). Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats. American journal of physiology. Renal physiology, 328(1), F48-F67. https://doi.org/10.1152/ajprenal.00065.2024

Homilius, C., Seefeldt, J. M., Hansen, J., Nielsen, B. R. R., de Paoli, F. V. & Boedtkjer, E. (2025). Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy. Acta Physiologica, 241(5), Artikel e70037. https://doi.org/10.1111/apha.70037

Ferapontov, A., Mellemkjær, A., Mcgettrick, H., Vorup-Jensen, T., Kragstrup, T. W. & Juul-Madsen, K. (2025). Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation. Journal of Translational Autoimmunity, 10, Artikel 100266. https://doi.org/10.1016/j.jtauto.2025.100266

Zein, L., Dietrich, M., Balta, D., Bader, V., Scheuer, C., Zellner, S., Weinelt, N., Vandrey, J., Mari, M. C., Behrends, C., Zunke, F., Winklhofer, K. F. & Van Wijk, S. J. L. (2025). Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival. Autophagy. Advance online publication. https://doi.org/10.1080/15548627.2024.2443945

Lou, S., Ryberg, A., Becher, N., Lund, I. C. B. & Vogel, I. (Accepteret/In press). Making Sense of a Prenatal Detection of Trisomy 16 Mosaicism in the Placenta: A Qualitative Study of Pregnant Women's Decision Making. Prenatal Diagnosis. https://doi.org/10.1002/pd.6751

Zeng, Y., Lv, W., Tao, H., Li, C., Jiang, S., Liang, Y., Chen, C., Yu, T., Li, Y., Wu, S., Cui, X., Liang, N., Wang, P., Xu, H., Dong, J., Teng, H., Chen, K., Mu, K., Fan, T. ... Han, P. (2025). Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneity. iScience, 28(1), 111510. Artikel 111510. https://doi.org/10.1016/j.isci.2024.111510

Thunbo, M. Ø., Vendelbo, J. H., Larsen, A., Witte, D. R. & Pedersen, L. H. (2025). Maternal Demographic Patterns in Medication use During Pregnancy: A Nationwide Register Study. Basic & Clinical Pharmacology & Toxicology, 136(4), Artikel e70020. https://doi.org/10.1111/bcpt.70020

Lohrmann, F., Efstratiou, A., Sørensen, U. B. S., Creti, R., Decheva, A., Křížová, P., Kozáková, J., Rodriguez-Granger, J., De La Rosa Fraile, M., Margarit, I., Rinaudo, D., Maione, D., Telford, J., Orefici, G., Kilian, M., Afshar, B., Melin, P., Berner, R., Hufnagel, M. ... on behalf of DEVANI Study Group (2025). Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study. Infection, 53(1), 373-381. https://doi.org/10.1007/s15010-024-02380-0

Johnsen, L. Ø., Friis, K. A., Møller-Madsen, M. K. & Damkier, H. H. (2025). Mechanisms of cerebrospinal fluid secretion by the choroid plexus epithelium: Application to various intracranial pathologies. Clinical Anatomy, 38(1), 63-74. https://doi.org/10.1002/ca.24199

Dittrich, A., Andersson, S. A., Busk, M., Hansen, K., Foldager, C. B., Palmfeldt, J., Andersen, A., Pedersen, M., Vendelbo, M., Nielsen, K. L. & Lauridsen, H. (2025). Metabolic changes during cardiac regeneration in the axolotl. Developmental Dynamics. Advance online publication. https://doi.org/10.1002/dvdy.70020

Madsen, K. S., Henriksen, M., Døssing, A., Poulsen, A. S., Oscar, R., Kragstrup, T., Ellegaard, K., Knop, F. K., Boesen, M., Hunter, D. J., Christensen, R. & Bliddal, H. (2025). Metformin treatment for patients with hand osteoarthritis: protocol for the multicentre, randomised, placebo-controlled METRO trial. BMJ Open, 15(3), Artikel e093831. Advance online publication. https://doi.org/10.1136/bmjopen-2024-093831

Lynderup, E. M., Vendelbo, M., Kirk, F. T., Vase, K. H., Alstrup, A. K. O., Rieder, T., DiSpirito, A. A., Semrau, J. D., Laursen, T. L., Ott, P., Zischka, H. & Sandahl, T. D. (Accepteret/In press). Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI. British Journal of Pharmacology.

Lutta, A., Liu, Q., Pedersen, G. K., Dong, M., Grohganz, H., Nielsen, L. H. & Schmidt, S. T. (Accepteret/In press). Microfluidic fabrication of pectin-coated liposomes for drug delivery. Drug Delivery and Translational Research. https://doi.org/10.1007/s13346-025-01812-0

Haidari, R., Fowler, W. J., Robinson, S. D., Johnson, R. T. & Warren, D. T. (2025). Microvascular endothelial cells display organ-specific responses to extracellular matrix stiffness. Current Research in Physiology, 8, Artikel 100140. https://doi.org/10.1016/j.crphys.2025.100140

Pozzo, E., Yedigaryan, L., Giarratana, N., Wang, C. C., Garrido, G. M., Degreef, E., Marini, V., Rinaldi, G., van der Veer, B. K., Sassi, G., Eelen, G., Planque, M., Fanzani, A., Koh, K. P., Carmeliet, P., Yustein, J. T., Fendt, S. M., Uyttebroeck, A. & Sampaolesi, M. (2025). miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma. Cell Reports, 44(1), Artikel 115171. https://doi.org/10.1016/j.celrep.2024.115171

Silva, N. R., Arjmand, S., Domingos, L. B., Chaves-Filho, A. M., Mottin, M., Real, C. C., Waszkiewicz, A. L., Gobira, P. H., Ferraro, A. N., Landau, A. M., Andrade, C. H., Müller, H. K., Wegener, G. & Joca, S. R. L. (2025). Modulation of the endocannabinoid system by (S)-ketamine in an animal model of depression. Pharmacological Research, 211, 107545. Artikel 107545. https://doi.org/10.1016/j.phrs.2024.107545

Larsen, M. L., Nørgaard, L., Linge, P., Larsen, J. B., Langkilde, H. Z., Hauge, E. M., Thiel, S., Voss, A., Bengtsson, A. & Troldborg, A. (2025). Molecular mechanisms underlying thrombosis in systemic lupus erythematosus – A Systematic review. Seminars in Arthritis and Rheumatism, 72, Artikel 152707. https://doi.org/10.1016/j.semarthrit.2025.152707

Rydder, P. M., Andreasen, L., Thomsen, S. H., Jensen, U. B., Becher, N., Dunø, M. & Vogel, I. (2025). Mosaic STS gene deletions in chorionic villus samples are often confined to the placenta, and they differ in size from STS gene deletions in patients with X-linked Ichthyosis. Placenta, 165, 16-22. https://doi.org/10.1016/j.placenta.2025.03.016

Holmberg, A., Pol-Fuster, J., Kuja-Halkola, R., Larsson, H., Lichtenstein, P., Chang, Z., D'Onofrio, B. M., Brikell, I., Sidorchuk, A., Isomura, K., Crowley, J. J., Martinsson, L., Rück, C., Mataix-Cols, D. & Fernández De La Cruz, L. (2025). Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders. BMJ Mental Health, 28(1), Artikel e301323. https://doi.org/10.1136/bmjment-2024-301323

Corydon, T. J. & Bek, T. (2025). Multiple gene therapy as a tool for regulating the expression of molecules involved in neovascular age-related macular degeneration. Progress in Retinal and Eye Research, 104, Artikel 101323. https://doi.org/10.1016/j.preteyeres.2024.101323

Boonkaew, S., Teodori, L., Vendelbo, M. H., Kjems, J. & Ferapontova, E. E. (2025). Nanobodies' duo facilitates ultrasensitive serum HER-2/neu immunoassays via enhanced avidity interactions. Analytica Chimica Acta, 1335, Artikel 343472. https://doi.org/10.1016/j.aca.2024.343472

Joca, S. (2025). Neurodegenerative disorders: Advances in neurobiology and new treatment perspectives. Basic and Clinical Pharmacology and Toxicology, 136(1), Artikel e14098. https://doi.org/10.1111/bcpt.14098

Grønnebæk, T. S., Haahr-Lillevang, H., Skov, M., Kelly, K., Kerr, N. R., Viteri, J. A., Jaworek, A., Bartlett, A., Bold, J., Hutchison, J., Quiroz, J., Tankisi, H., Pedersen, T. H., Andersen, H. & Arnold, W. D. (2025). Neuromuscular transmission deficits in patients with CMT and ClC-1 inhibition in CMT animal models. Annals of clinical and translational neurology, 12(2), 320-331. https://doi.org/10.1002/acn3.52252

Voloudakis, G., Therrien, K., Tomasi, S., Rajagopal, V. M., Choi, S. W., Demontis, D., Fullard, J. F., Børglum, A. D., O’Reilly, P. F., Hoffman, G. E. & Roussos, P. (2025). Neuropsychiatric polygenic scores are weak predictors of professional categories. Nature Human Behaviour, 9(3), 595-608. Artikel 2457. https://doi.org/10.1038/s41562-024-02074-5

Bedei, I., Bruder, J., Lund, I. C. B., Thomsen, S. H., Vogel, I., Maciel-Guerra, A. T., Alvarez-Nava, F., Crenshaw, M. L., Axt-Fliedner, R., Gravholt, C. H. & Skakkebæk, A. (2025). Non-Invasive Prenatal Testing by Cell-Free DNA (cfNIPT) for Detecting Turner Syndrome With Mosaicism and Structural Variants—Prenatal Findings and Postnatal Outcomes. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. Advance online publication. https://doi.org/10.1002/ajmg.c.32136

Schulz, H., Abdelfattah, F., Heinrich, A., Melnik, D., Sandt, V., Krüger, M., Wehland, M., Hoffmann, P., Cortés-Sánchez, J. L., Evert, M., Evert, K. & Grimm, D. (2025). Omics Investigations of Prostate Cancer Cells Exposed to Simulated Microgravity Conditions. Biomolecules, 15(2), Artikel 303. https://doi.org/10.3390/biom15020303

Fejerskov, O. & Manji, F. (2025). Oral Health Care - Past, Present and Future Perspectives. I O. Fejerskov & B. Nyvad (red.), Dental Caries : The disease and its clinical management (4 udg., s. 401-405). Wiley-Blackwell.

Chen, M. Y., Fulton, L. M., Huang, I., Liman, A., Hossain, S. S., Hamilton, C. D., Song, S., Geissmann, Q., King, K. C. & Haney, C. H. (2025). Order among chaos: High throughput MYCroplanters can distinguish interacting drivers of host infection in a highly stochastic system. PLOS Pathogens, 21(2 February), Artikel e1012894. https://doi.org/10.1371/journal.ppat.1012894

Broksø, A. D., Bendixen, L., Fammé, S., Mikkelsen, K., Jensen, T. I. & Bak, R. O. (2025). Orthogonal transcriptional modulation and gene editing using multiple CRISPR/Cas systems. Molecular Therapy, 33(1), 71-89. https://doi.org/10.1016/j.ymthe.2024.11.024

Alan Albayrak, E., Pinilla, E., Comerma Steffensen, S. G., Erac, Y., Yetik-Anacak, G., Simonsen, U. & Sevin, G. (2025). Osthole improves erectile function by increasing endogenous H2S production. European Journal of Pharmacology. https://doi.org/10.1016/j.ejphar.2025.177619

Suur, B. E., Karadimou, G., Willems, C. J. J. M., Bergman, O., Lengquist, M., Kronqvist, M., Baumgartner, R., Malin, S., Gisterå, A., Hansson, G. K., Mälarstig, A., Hedin, U., Ketelhuth, D. F. J. & Matic, L. (2025). PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis. Vascular Pharmacology, 159, Artikel 107490. https://doi.org/10.1016/j.vph.2025.107490

Janssen, N., van Polen, E. J., Daemen, J. H. T., Franssen, A. J. P. M., Hulsewé, K. W. E., Vissers, Y. L. J., Van Veer, H. G., de Paoli, F. V. & de Loos, E. R. (2025). Pectus excavatum revision surgery: a complex challenge requiring centralization of expertise. Journal of Thoracic Disease, 17(3), 1126-1130. https://doi.org/10.21037/jtd-24-1883

Gomez Del Val, A., Sánchez, A. B., Freire-Agulleiro, O., Pilar Martínez, M., Muñoz, M., Olmos, L., Sáenz-Medina, J., Comerma Steffensen, S. G., Simonsen, U., Rivera, L., López, M. F., Contreras, C. & Prieto, D. (2025). Penile endothelial dysfunction, impaired redox metabolism and blunted mitochondrial bioenergetics in diet-induced obesity: Compensatory role of H2O2. Free Radical Biology & Medicine, 230, 222-233. https://doi.org/10.1016/j.freeradbiomed.2025.02.004

Christiansen, J. R., Ferreira, S. A., Szymkowski, D. E., Jakobsson, J., Tansey, M. G. & Romero-Ramos, M. (2025). Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats. Neurobiology of Disease, 206, Artikel 106803. https://doi.org/10.1016/j.nbd.2025.106803

Bentestuen, M. S., Weis, C. N., Jeppesen, C. B., Thiele, L. S., Thirstrup, J. P., Cordero-Solorzano, J., Jensen, H. K., Starnawska, A., Hauser, A. S. & Gasse, C. (2025). Pharmacogenomic markers associated with drug-induced QT prolongation: a systematic review. Pharmacogenomics, 26(1-2), 53-72. https://doi.org/10.1080/14622416.2025.2481025

Sønderskov, M. B., Khatir, D. S., Kjærgaard, K. D., Hasselstrøm, J. B., Sørensen, L. K., Sædder, E. A. & Andersen, C. U. (2025). Pharmacokinetics and Side Effects of Δ⁹-Tetrahydrocannabinol and Cannabidiol in Patients with Different Stages of CKD. Kidney International Reports, 10(3), 707-719. https://doi.org/10.1016/j.ekir.2024.12.030

International Liaison Committee on Resuscitation ILCOR Advanced Paediatric Life Support Task Forces (2025). Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis. Resuscitation, 208, 110489. Artikel 110489. https://doi.org/10.1016/j.resuscitation.2025.110489

Jensen, M., Nielsen, S. F., Thiel, S., Hansen, S. W. K., Palarasah, Y., Svenningsen, P., Bech, J. N., Mose, F. H. & Jensen, B. L. (2025). Pilot Study of Sodium-Glucose Cotransporter 2 Inhibitor Empagliflozin Shows Reduced Intrarenal Complement Activation in Patients With Diabetes and CKD. Kidney International Reports, 10(2), 591-595. https://doi.org/10.1016/j.ekir.2024.11.014, https://doi.org/10.1016/j.ekir.2024.11.014

Wu, A., Wolley, M. J., Vesey, D., Terker, A. S., Welling, P. A., Fenton, R. A. & Stowasser, M. (2025). Plasma Potassium Negatively Correlates With Sodium Chloride Cotransporter Abundance and Phosphorylation in Urinary Extracellular Vesicles From Patients With Chronic Kidney Disease. Nephrology, 30(3), e70017. https://doi.org/10.1111/nep.70017

Sag, E., Balik, Z., Demir, S., Kaya, U. A., Sener, S., Cuceoglu, M. K., Atalay, E., Bocutcu, S., Vural, T., Tasdemir, N. K., Aydin, B., Bilginer, Y., Deleuran, B. & Ozen, S. (2025). Polyarticular juvenile idiopathic arthritis has a distinct co-inhibitor receptor profile. Rheumatology, 64(3), 1424-1430. https://doi.org/10.1093/rheumatology/keae306

Ahlqvist, V. H. & Ballin, M. (2025). Polygenic risk analysis in physical activity and health: why are the same results interpreted differently? British Journal of Sports Medicine, 59(3). https://doi.org/10.1136/bjsports-2024-108697

APEX consortium & Mortensen, P. B. (2025). Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population. Molecular Psychiatry, Artikel 2301. Advance online publication. https://doi.org/10.1038/s41380-025-02927-z

Gachon, F., Bugianesi, E., Castelnuovo, G., Oster, H., Pendergast, J. S. & Montagnese, S. (2025). Potential bidirectional communication between the liver and the central circadian clock in MASLD. NPJ Metabolic Health and Disease, 3(1), Artikel 15. https://doi.org/10.1038/s44324-025-00058-1

Kolding, L., Henriksen, JN., Sædder, EA., Ovesen, PG. & Pedersen, LH. (2025). Pregnancy Outcomes After Semaglutide Exposure. Basic and Clinical Pharmacology and Toxicology, 136(4), Artikel e70021. https://doi.org/10.1111/bcpt.70021

Henriksen, J. N., Rosenquist, S. B., Illum, D. G. & Andersen, C. U. (2025). Prevalence of Patients Admitted to Intensive Care After Administration of Chlordiazepoxide in the Emergency Room. Basic & Clinical Pharmacology & Toxicology, 136(4), e70018. https://doi.org/10.1111/bcpt.70018

Yuan, H., Song, Z., Sun, X.-Q., Song, C., Guo, L., Zhang, Q., Luo, Y., Yuan, C., Gao, J. & Jia, X. (2025). Profiling the cell diversity and tissue structure of aqueous humor circulatory system in human eyes using spatial single-cell RNA sequencing. Genes & diseases, 12(1), 101304. Artikel 101304. https://doi.org/10.1016/j.gendis.2024.101304

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Revideret 14.09.2020