Fogh, S., Dipace, G., Bie, A., Veiga-da-Cunha, M.
, Hansen, J., Kjeldsen, M., Mosegaard, S., Ribes, A.
, Gregersen, N., Aagaard, L., Schaftingen, E. V.
& Olsen, R. K. J. (2021).
Variants in the Ethylmalonyl-CoA Decarboxylase (ECHDC1) Gene; a Novel Player in Ethylmalonic Aciduria? Journal of Inherited Metabolic Disease,
44(5), 1215-1225.
https://doi.org/10.1002/jimd.12394
Herlin, L. K., Hansen, K. S., Bodilsen, J., Larsen, L., Brandt, C. T., Andersen, C. Ø., Hansen, B. R., von Lüttichau, H. R., Helweg-Larsen, J., Wiese, L.
, Storgaard, M., Nielsen, H.
& Mogensen, T. (2021).
Varicella Zoster Virus Encephalitis in Denmark From 2015 to 2019: A Nationwide Prospective Cohort Study.
Clinical Infectious Diseases,
72(7), 1192–1199.
https://doi.org/10.1093/cid/ciaa185
Torp, C. K., Brüner, M., Keller, K. K., Brouwer, E.
, Hauge, E.-M., McGonagle, D.
& Kragstrup, T. W. (2021).
Vasculitis therapy refines vasculitis mechanistic classification.
Autoimmunity Reviews,
20(6), Article 102829.
https://doi.org/10.1016/j.autrev.2021.102829
Fredes, F., Silva, M. A., Koppensteiner, P., Kobayashi, K., Joesch, M. & Shigemoto, R. (2021).
Ventro-dorsal Hippocampal Pathway Gates Novelty-Induced Contextual Memory Formation.
Current Biology,
31(1), 25-38.e5.
https://doi.org/10.1016/j.cub.2020.09.074
Tomac, J., Mazor, M., Lisnić, B., Golemac, M., Kveštak, D., Bralić, M., Bilić Zulle, L., Brinkmann, M. M., Dölken, L.
, Reinert, L. S., Paludan, S. R., Krmpotić, A., Jonjić, S. & Juranić Lisnić, V. (2021).
Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility.
Immunity,
54(7), 1478-1493.e6.
https://doi.org/10.1016/j.immuni.2021.04.020
Vestergaard, A. L., Justesen, S., Volqvartz, T., Aagaard, S. K., Andreasen, M. F., Lesnikova, I.
, Uldbjerg, N., Larsen, A. & Bor, P. (2021).
Vitamin D insufficiency among Danish pregnant women: Prevalence and association with adverse obstetric outcomes and placental vitamin D metabolism.
Acta Obstetricia et Gynecologica Scandinavica,
100(3), 480-488.
https://doi.org/10.1111/aogs.14019
Martis, L.-S., Højgaard, K., Holmes, M. C.
, Elfving, B. & Wiborg, O. (2021).
Vortioxetine ameliorates anhedonic-like behaviour and promotes strategic cognitive performance in a rodent touchscreen task.
Scientific Reports,
11(1), 9113. Article 9113.
https://doi.org/10.1038/s41598-021-88462-7
Holmen Olofsson, G.
, Idorn, M., Carnaz Simões, A. M., Aehnlich, P., Skadborg, S. K., Noessner, E., Debets, R., Moser, B., Met, Ö. & thor Straten, P. (2021).
Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens.
Frontiers in Immunology,
12, Article 645131.
https://doi.org/10.3389/fimmu.2021.645131
Hait, A. S., Thomsen, M. M., Larsen, S. M., Helleberg, M.
, Mardahl, M., Barfod, T. S.
, Christiansen, M., Brandt, C.
& Mogensen, T. H. (2021).
Whole-Exome Sequencing of Patients With Recurrent HSV-2 Lymphocytic Mollaret Meningitis.
The Journal of Infectious Diseases,
223(10), 1776-1786.
https://doi.org/10.1093/infdis/jiaa589
Stokholm, K., Thomsen, M. B., Phan, J. A., Møller, L. K.
, Bay-Richter, C., Christiansen, S. H., Woldbye, D. P. D.
, Romero-Ramos, M. & Landau, A. M. (2021).
α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease.
Biomedicines,
9(12), Article 1876.
https://doi.org/10.3390/biomedicines9121876
Delaidelli, A.
, Richner, M., Jiang, L., van der Laan, A., Bergholdt Jul Christiansen, I., Ferreira, N., Nyengaard, J. R., Vægter, C. B., Jensen, P. H., Mackenzie, I. R., Sorensen, P. H.
& Jan, A. (2021).
α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.
Acta Neuropathologica Communications,
9(1), Article 105.
https://doi.org/10.1186/s40478-021-01209-3
Mose, M., Møller, N., Jessen, N., Mikkelsen, U. R., Christensen, B.
, Rakvaag, E., Hartmann, B., Holst, J. J.
, Jørgensen, J. O. L. & Rittig, N. (2021).
β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion during Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial.
The Journal of Nutrition,
151(6), 1462-1472.
https://doi.org/10.1093/jn/nxab010
Lubberding, A. F., Pereira, L., Xue, J., Gottlieb, L. A.
, Matchkov, V. V., Gomez, A. M. & Thomsen, M. B. (2020).
Aberrant sinus node firing during β-adrenergic stimulation leads to cardiac arrhythmias in diabetic mice.
Acta Physiologica (Print),
229(1), Article e13444.
https://doi.org/10.1111/apha.13444
Staehr, C., Rajanathan, R., Postnov, D.
, Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L.
, Aalkjær, C. & Matchkov, V. (2020).
Abnormal neurovascular coupling as a cause of excess cerebral vasodilation in familial migraine.
Cardiovascular Research,
116(12), 2009-2020. Article cvz306.
https://doi.org/10.1093/cvr/cvz306
Pedersen, M. A., Jensen-Fangel, S., Nielsen, E., Borghammer, P. & Vendelbo, M. H. (2020).
Absent 18F-FDG Uptake in the Brain-Unsuspected Brain Death.
Clinical Nuclear Medicine,
45(10), e433-e434.
https://doi.org/10.1097/RLU.0000000000003237
Bernth Jensen, J. M., Petersen, M. S., Ellerman-Eriksen, S., Møller, B. K., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2020).
Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity.
Scientific Reports,
10(1), Article 4611.
https://doi.org/10.1038/s41598-020-61632-9
Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020).
A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system.
The Journal of Biological Chemistry,
295(26), 8746-8758.
https://doi.org/10.1074/jbc.RA119.012339
Henriksen, T.
, Dalhoff, K. P., Hansen, H. E., Brenneche, A. W., Lønberg, U. S.
& Danielsen, E. H. (2020).
Access and Use of Device-Aided Therapies for Parkinson’s Disease in Denmark.
Movement Disorders Clinical Practice,
7(6), 656-663.
https://doi.org/10.1002/mdc3.12988
Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-Valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V.
, Bergmann, T. B., Bystron, I.
, Capogna, M., Chang, Y., Clemens, A., de Kock, C. P. J., DeFelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D. ... Lein, E. (2020).
A community-based transcriptomics classification and nomenclature of neocortical cell types.
Nature Neuroscience,
23(12), 1456-1468.
https://doi.org/10.1038/s41593-020-0685-8
Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R.
, Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D.
, Mazarakis, S. M. M., Lojek, N.
, Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B.
, Thiel, S. & Andersen, G. R. (2020).
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Journal of Immunology,
205(8), 2287-2300.
https://doi.org/10.4049/jimmunol.2000752
Carstensen, M., Christensen, T., Stilund, M. L. M., Møller, H. J., Petersen, E. L. & Petersen, T. (2020).
Activated monocytes and markers of inflammation in newly diagnosed multiple sclerosis.
Immunology and Cell Biology,
98(7), 549-562.
https://doi.org/10.1111/imcb.12337
Pedersen, S. A., Klesse, T.
, Andreasen, M. F., Dalhoff, K. P.
& Andersen, C. U. (2020).
Active chlordiazepoxide metabolites in a patient needing life support after treatment of alcohol abstinence.
Basic & Clinical Pharmacology & Toxicology,
127(5), 438-441.
https://doi.org/10.1111/bcpt.13449
Weinschutz Mendes, H., Boldt, A. W., Stahlke, E.
, Jensenius, J. C., Thiel, S. & Messias-Reason, I. J. T. (2020).
Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.
PLOS Neglected Tropical Diseases ,
14(4), 1-20. Article e0007534.
https://doi.org/10.1371/journal.pntd.0007534
Paksarian, D.
, Trabjerg, B. B., Merikangas, K. R.
, Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T.
, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T. (2020).
Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression.
British Journal of Psychiatry,
217(1), 390-396.
https://doi.org/10.1192/bjp.2020.8
Skorstengaard, M. H., Jensen, A. B., Andreassen, P., Brogaard, T., Bendstrup, E., Løkke, A., Aagaard, S., Wiggers, H. & Neergaard, M. A. (2020).
Advance care planning and place of death, hospitalisation and actual place of death in lung, heart and cancer disease: a randomised controlled trial.
BMJ Supportive & Palliative Care,
10(4), E37. Article e37.
https://doi.org/10.1136/bmjspcare-2018-001677
Khatri, S., Hansen, J., Clausen, M. H.
, Kragstrup, T. W., Hung, S. C., Mellins, E. & Astakhova, K. (2020).
A first in class therapeutic nanoparticle for specific targeting of anti-citrullinated protein antibody ameliorates serum transfer and collagen induced arthritis.
Annals of the Rheumatic Diseases,
79(Suppl.1), 208. Article LB0002.
https://doi.org/10.1136/annrheumdis-2020-eular.6754
Christensen, N. R., De Luca, M., Lever, M. B.
, Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T. ... Madsen, K. L. (2020).
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
EMBO Molecular Medicine,
12(6), Article 11248.
https://doi.org/10.15252/emmm.201911248
Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J.
, Børglum, A. D., Daly, M. J.
, Mors, O., Hougaard, D. M.
, Mortensen, P. B., Werge, T., Nordentoft, M., Thompson, W. K. & Benros, M. E. (2020).
A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness.
Human Genetics,
139(5), 593-604.
https://doi.org/10.1007/s00439-020-02140-8
Johnson, E. C.
, Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T.-K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E. ... Psychiatric Genomics Consortium Substance Use Disorders Workgroup (2020).
A large-scale genome-wide association study meta-analysis of cannabis use disorder.
The Lancet Psychiatry,
7(12), 1032-1045.
https://doi.org/10.1016/S2215-0366(20)30339-4
Purves, K. L., Coleman, J. R. I.
, Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M.
, Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M.
, Mors, O. ... Eley, T. C. (2020).
A major role for common genetic variation in anxiety disorders.
Molecular Psychiatry,
25, 3292-3303.
https://doi.org/10.1038/s41380-019-0559-1
Sjöstedt, E., Zhong, W., Fagerberg, L., Karlsson, M., Mitsios, N., Adori, C., Oksvold, P., Edfors, F., Limiszewska, A., Hikmet, F.
, Huang, J., Du, Y.
, Lin, L., Dong, Z., Yang, L., Liu, X., Jiang, H., Xu, X., Wang, J. ... Mulder, J. (2020).
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Science,
367(6482), Article 5947.
https://doi.org/10.1126/science.aay5947
Liu, Y.
, Xu, W., Huang, Z. H., Guo, J.
, Fedosova, N. & Jiang, R. W. (2020).
An Efficient Strategy for the Chemo-Enzymatic Synthesis of Bufalin Glycosides with Improved Water Solubility and Inhibition against Na+, K+-ATPase.
Chemistry and Biodiversity,
17(11), Article e2000529.
https://doi.org/10.1002/cbdv.202000529
Toft, G., Heide-Jørgensen, U., van Haalen, H., James, G., Hedman, K.
, Birn, H., Christiansen, C. F. & Thomsen, R. W. (2020).
Anemia and clinical outcomes in patients with non-dialysis dependent or dialysis dependent severe chronic kidney disease: a Danish population-based study.
Journal of Nephrology,
33(1), 147-156.
https://doi.org/10.1007/s40620-019-00652-9
Wehland, M., Simonsen, U., Buus, N. H., Krüger, M.
& Grimm, D. (2020).
An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension.
Expert Opinion on Pharmacotherapy,
21(10), 1133-1143.
https://doi.org/10.1080/14656566.2020.1735356
Bordoni, L., Jiménez, E. G., Nielsen, S.
, Østergaard, L. & Frische, S. (2020).
A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics.
Experimental animals,
69(1), 92-103.
https://doi.org/10.1538/expanim.19-0040
Xue, J., Thomas, L., Tahmasbi, M., Valdez, A., Dominguez Rieg, J. A.
, Fenton, R. A. & Rieg, T. (2020).
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.
Clinical Science,
134(8), 941-953.
https://doi.org/10.1042/CS20200065
Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H.
, Kalucka, J., Sokol, L., García-Caballero, M., Zheng, Y., Qian, J., Teuwen, L.-A., Khan, S., Boeckx, B., Wauters, E., Decaluwé, H., De Leyn, P.
... Carmeliet, P. (2020).
An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates.
Cancer Cell,
37(1), 21-36.e13.
https://doi.org/10.1016/j.ccell.2019.12.001
Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H.
, Kalucka, J., Sokol, L., Garcia-Caballero, M., Zheng, Y., Qian, J., Teuwen, L.-A., Khan, S., Boeckx, B., Wauters, E., Decaluwe, H., De Leyn, P.
... Carmeliet, P. (2020).
An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates (vol 37, pg 21.e1, 2020).
Cancer Cell,
37(3), 421-421.
https://doi.org/10.1016/j.ccell.2020.03.002
Bie, A. S., Cömert, C., Körner, R.
, Corydon, T. J., Palmfeldt, J., Hipp, M. S., Hartl, F. U.
& Bross, P. (2020).
An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space.
Cell Stress & Chaperones,
25(3), 407-416.
https://doi.org/10.1007/s12192-020-01080-6
Damsgaard, C., Lauridsen, H., Harter, T. S., Kwan, G. T.
, Thomsen, J. S., Funder, A. M. D., Supuran, C. T., Tresguerres, M., Matthews, P. GD. & Brauner, C. J. (2020).
A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina.
eLife,
9, 1-20. Article e58995.
https://doi.org/10.7554/eLife.58995
Mahmoudi, R., Aghaei, S., Salehpour, Z., Mousavizadeh, A., Khoramrooz, S. S., Taheripour Sisakht, M.
, Christiansen, G., Baneshi, M., Karimi, B. & Bardania, H. (2020).
Antibacterial and antioxidant properties of phyto-synthesized silver nanoparticles using Lavandula stoechas extract.
Applied Organometallic Chemistry,
34(2), Article e5394.
https://doi.org/10.1002/aoc.5394
Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R.
, Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B.
, Laursen, N. S., Carroll, M. C.
& Andersen, G. R. (2020).
An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
Journal of Immunology,
205(6), 1678-1694.
https://doi.org/10.4049/jimmunol.2000528