Abramochkin, D. V., Kuzmin, V. S.
, Matchkov, V., Kamensky, A. A.
& Wang, T. (2021).
The snake heart pacemaker is localized near the sinoatrial valve.
Journal of Experimental Biology,
224(16), Article jeb242778.
https://doi.org/10.1242/JEB.242778
Schack, V. R., Rossen, L. S., Ekebjærg, C. C., Thuesen, K. K. H., Bundgaard, B. & Höllsberg, P. B. (2021).
The Tetraspanin Protein CD9 Modulates Infection with Human Herpesvirus 6A and 6B in a CD46-Dependent Manner.
Journal of Virology,
95(8), Article e02259-20.
https://doi.org/10.1128/JVI.02259-20
Vareecal Joseph, J., Blaavand, M. S., Daubon, T., Kruyt, F. AE.
& Thomsen, M. K. (2021).
Three-dimensional culture models to study glioblastoma — current trends and future perspectives.
Current Opinion in Pharmacology,
61, 91-97.
https://doi.org/10.1016/j.coph.2021.08.019
Miles, A. E., Dos Santos, F. C., Byrne, E. M., Renteria, M. E., McIntosh, A. M., Adams, M. J., Pistis, G., Castelao, E., Preisig, M., Baune, B. T., Schubert, K. O., Lewis, C. M., Jones, L. A., Jones, I., Uher, R., Smoller, J. W., Perlis, R. H., Levinson, D. F., Potash, J. B. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021).
Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk.
Neuropsychopharmacology,
46(13), 2304-2311.
https://doi.org/10.1038/s41386-021-01189-x
Prat-Duran, J., Pinilla, E., Nørregaard, R., Simonsen, U. & Buus, N. H. (2021).
Transglutaminase 2 as a novel target in chronic kidney disease - Methods, mechanisms and pharmacological inhibition.
Pharmacology & Therapeutics,
222, Article 107787.
https://doi.org/10.1016/j.pharmthera.2020.107787
Pinilla, E., Comerma Steffensen, S. G., Prat Duran, J., Rivera, L.
, Matchkov, V., Buus, N. H. & Simonsen, U. (2021).
Transglutaminase 2 Inhibitor LDN 27219 Age-Dependently Lowers Blood Pressure and Improves Endothelium-Dependent Vasodilation in Resistance Arteries.
Hypertension,
77(1), 216-227.
https://doi.org/10.1161/HYPERTENSIONAHA.120.15352
Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M.
, Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, T., Lage, K. & Regeneron Genetics Center (2021).
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.
Nature Communications,
12(1), Article 5276.
https://doi.org/10.1038/s41467-021-25014-7
Ferreira, N., Gonçalves, N. P., Jan, A., Jensen, N. M., van der Laan, A., Mohseni, S.
, Vægter, C. B. & Jensen, P. H. (2021).
Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain.
Acta Neuropathologica Communications,
9(1), Article 31.
https://doi.org/10.1186/s40478-021-01131-8
Petersen, A. G., Lind, P. C., Jensen, A.-S. B., Eggertsen, M. A., Granfeldt, A. & Simonsen, U. (2021).
Treatment with senicapoc in a porcine model of acute respiratory distress syndrome.
Intensive Care Medicine Experimental,
9(1), Article 20.
https://doi.org/10.1186/s40635-021-00381-z
Hald, S. M., Möller, S., García Rodríguez, L. A., Salman, R. A. S., Sharma, M., Christensen, H.
, Hellfritzsch, M., Pottegård, A., Hallas, J. & Gaist, D. (2021).
Trends in Incidence of Intracerebral Hemorrhage and Association with Antithrombotic Drug Use in Denmark, 2005-2018.
JAMA network open,
4(5), Article e218380.
https://doi.org/10.1001/jamanetworkopen.2021.8380
Hatje, F., Wedekind, U., Sachs, W., Loreth, D., Reichelt, J.
, Demir, F., Kosub, C., Heintz, L., Tomas, N., Huber, T., Skuza, S., Sachs, M., Zielinski, S.
, Rinschen, M. & Meyer-Schwesinger, C. (2021).
Tripartite Separation of Glomerular Cell-Types and Proteomes From Reporter-Free Mice.
Journal of the American Society of Nephrology : JASN,
32(9), 2175-2193.
https://doi.org/10.1681/ASN.2020091346
Teuwen, L. A., De Rooij, L. P. M. H., Cuypers, A., Rohlenova, K., Dumas, S. J., García-Caballero, M., Meta, E., Amersfoort, J., Taverna, F., Becker, L. M., Veiga, N., Cantelmo, A. R., Geldhof, V., Conchinha, N. V.
, Kalucka, J., Treps, L., Conradi, L. C., Khan, S., Karakach, T. K.
... Carmeliet, P. (2021).
Tumor vessel co-option probed by single-cell analysis.
Cell Reports,
35(11), Article 109253.
https://doi.org/10.1016/j.celrep.2021.109253
Hudecz, D., Sigurdardóttir, S. B.
, Christensen, S. C., Hempel, C., Urquhart, A. J., Andresen, T. L.
& Nielsen, M. S. (2021).
Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells.
PLOS ONE,
16(4 ), Article e0249686.
https://doi.org/10.1371/journal.pone.0249686
Cong, J., Chang, S.-J.
, Thomsen, J. S., Andreasen, A., Chen, X., Xing, J., Zhang, J., Gu, L. & Zhai, X.-Y. (2021).
Ultrastructural identification of developing proximal tubules based on three-dimensional reconstruction.
Veterinary Medicine and Science,
7(5), 1989-1998.
https://doi.org/10.1002/vms3.558
Seppälä, T. T., Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L. ... Møller, P. (2021).
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
European Journal of Cancer,
148, 124-133.
https://doi.org/10.1016/j.ejca.2021.02.022
Nielsen, A. J., Nielsen, M. C., Birn, H., Ivarsen, P., Møller, H. J. & Hviid, C. V. B. (2021).
Urine soluble CD163 (sCD163) as biomarker in glomerulonephritis: stability, reference interval and diagnostic performance.
Clinical Chemistry and Laboratory Medicine,
59(4), 701-709.
https://doi.org/10.1515/cclm-2020-0466
Pottegård, A., Lund, L. C., Henriksen, D. P., Folkestad, L.
, Hellfritzsch, M., Hallas, J. & Kristensen, K. B. (2021).
Use of dipeptidyl peptidase-4 inhibitors and risk of splanchnic vein thrombosis: A Danish nationwide new-user active comparator cohort study.
Diabetes, Obesity and Metabolism,
23(2), 648-652.
https://doi.org/10.1111/dom.14253
Arslanova, A., Shafaattalab, S., Ye, K., Asghari, P., Lin, L., Kim, B. R., Roston, T. M., Hove-Madsen, L., Van Petegem, F., Sanatani, S., Moore, E., Lynn, F., Søndergaard, M.
, Luo, Y., Chen, S. R. W. & Tibbits, G. F. (2021).
Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia.
Current Protocols,
1(12), Article e320.
https://doi.org/10.1002/cpz1.320
Lykke, M. R., Becher, N. H., Haahr, T., Boedtkjer, E., Jensen, J. S.
& Uldbjerg, N. (2021).
Vaginal, cervical and uterine pH in women with normal and abnormal vaginal microbiota.
Pathogens,
10(2), Article 90.
https://doi.org/10.3390/pathogens10020090
Bolin, K., Imgenberg-Kreuz, J., Leonard, D., Sandling, J. K., Alexsson, A., Pucholt, P., Haarhaus, M. L., Almlöf, J. C., Nititham, J., Jönsen, A., Sjöwall, C., Bengtsson, A. A., Rantapää-Dahlqvist, S., Svenungsson, E., Gunnarsson, I., Syvänen, A.-C., Lerang, K.
, Troldborg, A., Voss, A. ... Nordmark, G. (2021).
Variants in BANK1 are associated with lupus nephritis of European ancestry.
Genes and Immunity,
22(3), 194-202.
https://doi.org/10.1038/s41435-021-00142-8
Fogh, S., Dipace, G., Bie, A., Veiga-da-Cunha, M.
, Hansen, J., Kjeldsen, M., Mosegaard, S., Ribes, A.
, Gregersen, N., Aagaard, L., Schaftingen, E. V.
& Olsen, R. K. J. (2021).
Variants in the Ethylmalonyl-CoA Decarboxylase (ECHDC1) Gene; a Novel Player in Ethylmalonic Aciduria? Journal of Inherited Metabolic Disease,
44(5), 1215-1225.
https://doi.org/10.1002/jimd.12394
Bauer, M., Glenn, T., Achtyes, E. D., Alda, M., Agaoglu, E., Altınbaş, K., Andreassen, O. A., Angelopoulos, E., Ardau, R., Vares, E. A., Aydin, M., Ayhan, Y., Baethge, C., Bauer, R., Baune, B. T., Balaban, C., Becerra-Palars, C., Behere, A. P., Behere, P. B. ... Whybrow, P. C. (2021).
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder.
International Journal of Bipolar Disorders,
9(1), Article 26.
https://doi.org/10.1186/s40345-021-00231-7
Herlin, L. K., Hansen, K. S., Bodilsen, J., Larsen, L., Brandt, C. T., Andersen, C. Ø., Hansen, B. R., von Lüttichau, H. R., Helweg-Larsen, J., Wiese, L.
, Storgaard, M., Nielsen, H.
& Mogensen, T. (2021).
Varicella Zoster Virus Encephalitis in Denmark From 2015 to 2019: A Nationwide Prospective Cohort Study.
Clinical Infectious Diseases,
72(7), 1192–1199.
https://doi.org/10.1093/cid/ciaa185
Torp, C. K., Brüner, M., Keller, K. K., Brouwer, E.
, Hauge, E.-M., McGonagle, D.
& Kragstrup, T. W. (2021).
Vasculitis therapy refines vasculitis mechanistic classification.
Autoimmunity Reviews,
20(6), Article 102829.
https://doi.org/10.1016/j.autrev.2021.102829
Fredes, F., Silva, M. A., Koppensteiner, P., Kobayashi, K., Joesch, M. & Shigemoto, R. (2021).
Ventro-dorsal Hippocampal Pathway Gates Novelty-Induced Contextual Memory Formation.
Current Biology,
31(1), 25-38.e5.
https://doi.org/10.1016/j.cub.2020.09.074
Tomac, J., Mazor, M., Lisnić, B., Golemac, M., Kveštak, D., Bralić, M., Bilić Zulle, L., Brinkmann, M. M., Dölken, L.
, Reinert, L. S., Paludan, S. R., Krmpotić, A., Jonjić, S. & Juranić Lisnić, V. (2021).
Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility.
Immunity,
54(7), 1478-1493.e6.
https://doi.org/10.1016/j.immuni.2021.04.020
Vestergaard, A. L., Justesen, S., Volqvartz, T., Aagaard, S. K., Andreasen, M. F., Lesnikova, I.
, Uldbjerg, N., Larsen, A. & Bor, P. (2021).
Vitamin D insufficiency among Danish pregnant women: Prevalence and association with adverse obstetric outcomes and placental vitamin D metabolism.
Acta Obstetricia et Gynecologica Scandinavica,
100(3), 480-488.
https://doi.org/10.1111/aogs.14019
Martis, L.-S., Højgaard, K., Holmes, M. C.
, Elfving, B. & Wiborg, O. (2021).
Vortioxetine ameliorates anhedonic-like behaviour and promotes strategic cognitive performance in a rodent touchscreen task.
Scientific Reports,
11(1), 9113. Article 9113.
https://doi.org/10.1038/s41598-021-88462-7
Holmen Olofsson, G.
, Idorn, M., Carnaz Simões, A. M., Aehnlich, P., Skadborg, S. K., Noessner, E., Debets, R., Moser, B., Met, Ö. & thor Straten, P. (2021).
Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens.
Frontiers in Immunology,
12, Article 645131.
https://doi.org/10.3389/fimmu.2021.645131
Hait, A. S., Thomsen, M. M., Larsen, S. M., Helleberg, M.
, Mardahl, M., Barfod, T. S.
, Christiansen, M., Brandt, C.
& Mogensen, T. H. (2021).
Whole-Exome Sequencing of Patients With Recurrent HSV-2 Lymphocytic Mollaret Meningitis.
The Journal of Infectious Diseases,
223(10), 1776-1786.
https://doi.org/10.1093/infdis/jiaa589
Stokholm, K., Thomsen, M. B., Phan, J. A., Møller, L. K.
, Bay-Richter, C., Christiansen, S. H., Woldbye, D. P. D.
, Romero-Ramos, M. & Landau, A. M. (2021).
α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease.
Biomedicines,
9(12), Article 1876.
https://doi.org/10.3390/biomedicines9121876
Delaidelli, A.
, Richner, M., Jiang, L., van der Laan, A., Bergholdt Jul Christiansen, I., Ferreira, N., Nyengaard, J. R., Vægter, C. B., Jensen, P. H., Mackenzie, I. R., Sorensen, P. H.
& Jan, A. (2021).
α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.
Acta Neuropathologica Communications,
9(1), Article 105.
https://doi.org/10.1186/s40478-021-01209-3
Mose, M., Møller, N., Jessen, N., Mikkelsen, U. R., Christensen, B.
, Rakvaag, E., Hartmann, B., Holst, J. J.
, Jørgensen, J. O. L. & Rittig, N. (2021).
β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion during Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial.
The Journal of Nutrition,
151(6), 1462-1472.
https://doi.org/10.1093/jn/nxab010
Lubberding, A. F., Pereira, L., Xue, J., Gottlieb, L. A.
, Matchkov, V. V., Gomez, A. M. & Thomsen, M. B. (2020).
Aberrant sinus node firing during β-adrenergic stimulation leads to cardiac arrhythmias in diabetic mice.
Acta Physiologica (Print),
229(1), Article e13444.
https://doi.org/10.1111/apha.13444
Staehr, C., Rajanathan, R., Postnov, D.
, Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L.
, Aalkjær, C. & Matchkov, V. (2020).
Abnormal neurovascular coupling as a cause of excess cerebral vasodilation in familial migraine.
Cardiovascular Research,
116(12), 2009-2020. Article cvz306.
https://doi.org/10.1093/cvr/cvz306
Pedersen, M. A., Jensen-Fangel, S., Nielsen, E., Borghammer, P. & Vendelbo, M. H. (2020).
Absent 18F-FDG Uptake in the Brain-Unsuspected Brain Death.
Clinical Nuclear Medicine,
45(10), e433-e434.
https://doi.org/10.1097/RLU.0000000000003237
Bernth Jensen, J. M., Petersen, M. S., Ellerman-Eriksen, S., Møller, B. K., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2020).
Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity.
Scientific Reports,
10(1), Article 4611.
https://doi.org/10.1038/s41598-020-61632-9
Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020).
A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system.
The Journal of Biological Chemistry,
295(26), 8746-8758.
https://doi.org/10.1074/jbc.RA119.012339
Henriksen, T.
, Dalhoff, K. P., Hansen, H. E., Brenneche, A. W., Lønberg, U. S.
& Danielsen, E. H. (2020).
Access and Use of Device-Aided Therapies for Parkinson’s Disease in Denmark.
Movement Disorders Clinical Practice,
7(6), 656-663.
https://doi.org/10.1002/mdc3.12988
Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-Valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V.
, Bergmann, T. B., Bystron, I.
, Capogna, M., Chang, Y., Clemens, A., de Kock, C. P. J., DeFelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D. ... Lein, E. (2020).
A community-based transcriptomics classification and nomenclature of neocortical cell types.
Nature Neuroscience,
23(12), 1456-1468.
https://doi.org/10.1038/s41593-020-0685-8
Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R.
, Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D.
, Mazarakis, S. M. M., Lojek, N.
, Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B.
, Thiel, S. & Andersen, G. R. (2020).
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Journal of Immunology,
205(8), 2287-2300.
https://doi.org/10.4049/jimmunol.2000752