Peer-reviewed publikationer

Peer-reviewed publications

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Trist, B. G., Wright, C. J., Rangel, A., Cottle, L., Prasad, A., Jensen, N. M., Gram, H., Dzamko, N., Jensen, P. H. & Kirik, D. (2024). Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain. npj Parkinson's Disease , 10(1), Artikel 217. https://doi.org/10.1038/s41531-024-00830-y

Trinh, N. T. H., Semark, B. D., Munk-Olsen, T., Liu, X., Thapa, S. B., Yilmaz, Z., Petersen, L. V. & Lupattelli, A. (2023). Antidepressant treatment in pregnancy: a Danish registry linkage study in pregnant women with pre-existing obsessive-compulsive disorder. Translational Psychiatry, 13(1), Artikel 223. https://doi.org/10.1038/s41398-023-02516-0

Trimpert, C., van den Berg, D. T. M., Fenton, R. A., Klussmann, E. & Deen, P. M. T. (2012). Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus. Nephrology Dialysis Transplantation, 27(12), 4389-97. https://doi.org/10.1093/ndt/gfs292

Triel, C., Vestergaard, M. E., Bolund, L., Jensen, T. G., Jensen, U. B. & Jensen, U. B. (2004). Side population cells in human and mouse epidermis lack stem cell characteristics. Experimental Cell Research, 295(1), 79-90. https://doi.org/10.1016/j.yexcr.2003.11.032

Triel, C., Vestergaard, M. E., Bolund, L., Jensen, T. G. & Jensen, U. B. (2007). Corrigendum to "Side population cells in human and mouse epidermis lack stem cell characteristics" [Exp. Cell Res. 295 (2004) 79-90] (DOI:10.1016/j.yexcr.2003.11.032). Experimental Cell Research, 313(18). https://doi.org/10.1016/j.yexcr.2007.05.007

Treves, S., Larini, F., Menegazzi, P., Steinberg, T. H., Koval, M., Vilsen, B., Andersen, J. P. & Zorzato, F. (1994). Alteration of intracellular Ca²⁺ transients in COS-7 cells transfected with the cDNA encoding skeletal-muscle ryanodine receptor carrying a mutation associated with malignant hyperthermia. Biochemical Journal, 301(3), 661-665. https://doi.org/10.1042/bj3010661

Treves, S., Vilsen, B., Chiozzi, P., Andersen, J. P. & Zorzato, F. (1992). Molecular cloning, functional expression and tissue distribution of the cDNA encoding frog skeletal muscle calsequestrin. Biochemical Journal, 283(3), 767-772. https://doi.org/10.1042/bj2830767

Treutlein, J., Mühleisen, T. W., Frank, J., Mattheisen, M., Herms, S., Ludwig, K. U., Treutlein, T., Schmael, C., Strohmaier, J., Bösshenz, K. V., Breuer, R., Paul, T., Witt, S. H., Schulze, T. G., Schlösser, R. G. M., Nenadic, I., Sauer, H., Becker, T., Maier, W. ... Rietschel, M. (2009). Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter. Schizophrenia Research, 111(1-3), 123-30. https://doi.org/10.1016/j.schres.2009.03.011

Treur, J. L., Demontis, D., Smith, G. D., Sallis, H., Richardson, T. G., Wiers, R. W., Børglum, A. D., Verweij, K. J. H. & Munafò, M. R. (2021). Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization. Addiction Biology, 26(1), Artikel e12849. https://doi.org/10.1111/adb.12849

Treppendahl, M. B., Kristensen, L. S. & Grønbæk, K. (2014). Predicting response to epigenetic therapy. Journal of Clinical Investigation, 124(1), 47-55. https://doi.org/10.1172/JCI69737

Trepiccione, F., Capasso, G., Nielsen, S. & Christensen, B. M. (2013). Evaluation of cellular plasticity in the collecting duct during recovery from lithium-induced nephrogenic diabetes insipidus. A J P: Renal Physiology (Online), 305(6), F919-29. https://doi.org/10.1152/ajprenal.00152.2012

Trepiccione, F. & Christensen, B. M. (2010). Lithium-induced nephrogenic diabetes insipidus: new clinical and experimental findings. Journal of Nephrology, 23 Suppl 16, S43-8.

Trepiccione, F., Pisitkun, T., Hoffert, J. D., Poulsen, S. B., Capasso, G., Nielsen, S., Knepper, M. A., Fenton, R. A. & Christensen, B. M. (2014). Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2. Kidney International. https://doi.org/10.1038/ki.2014.107

Trepiccione, F., Iena, F. M., Catalini, L., Carpi, F. M., Koed, M. & Frische, S. (2017). Measurement of total CO2 in microliter samples of urine and other biological fluids using infrared detection of CO2. Pflügers Archiv - European Journal of Physiology, 469(10), 1267-1275. https://doi.org/10.1007/s00424-017-1997-8

Trepiccione, F., Altobelli, C., Capasso, G., Christensen, B. M. & Frische, S. (2018). Lithium increases ammonium excretion leading to altered urinary acid-base buffer composition. Journal of Nephrology, 31(3), 385-393. https://doi.org/10.1007/s40620-017-0460-4

Trelle, M. B., Hirschberg, D., Jansson, A., Ploug, M., Roepstorff, P., Andreasen, P. & Jørgensen, T. (2012). Hydrogen/Deuterium Exchange Mass Spectrometry Reveals Specific Changes in the Local Flexibility of Plasminogen Activator Inhibitor 1 upon Binding to the Somatomedin B Domain of Vitronectin. Biochemistry, 51(41), 8256–8266. https://doi.org/10.1021/bi3008998

Traversa, D., Simonetti, G., Tolomeo, D., Visci, G., Macchia, G., Ghetti, M., Martinelli, G., Kristensen, L. S. & Storlazzi, C. T. (2022). Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease. British Journal of Cancer, 126(6), 835-850. https://doi.org/10.1038/s41416-021-01584-7

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018). Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory. Neuropsychopharmacology, 43(13), 2572-2577. https://doi.org/10.1038/s41386-018-0092-y

Tran, T. L., Bek, T., Holm, L., la Cour, M., Nielsen, S., Prause, J. U., Rojek, A., Hamann, S. & Heegaard, S. (2013). Aquaporins 6-12 in the human eye. Acta Ophthalmologica (Online), 91(6), 557-63. https://doi.org/10.1111/j.1755-3768.2012.02547.x

Toyoshima, C., Kanai, R. & Cornelius, F. (2011). First crystal structure of Na⁺,K⁺-ATPase: New light on the oldest ion pump. Structure, 19, 1732-1738.

Toyoshima, C. & Cornelius, F. (2013). New crystal structures of P-type ATPases: excitement continues. Current Opinion in Structural Biology, 23, 507-514.

Toxvig, A. K., Wehland, M., Grimm, D., Infanger, M. & Krüger, M. (2019). A Focus on Riociguat in the Treatment of Pulmonary Arterial Hypertension. Basic & Clinical Pharmacology & Toxicology, 125(3), 202-214. https://doi.org/10.1111/bcpt.13272

Toustrup-Jensen, M. S., Hauge, M. & Vilsen, B. (2001). Mutational effects on conformational changes of the dephospho-and phospho-forms of the Na⁺,K⁺-ATPase. Biochemistry, 40, 5521-5532.

Toustrup-Jensen, M. S. & Vilsen, B. (2003). Functional consequences of alterations to Ile²⁷⁹, Ile²⁸³, Glu²⁸⁴, His²⁸⁵, Phe²⁸⁶, and His²⁸⁸, in the NH₂-terminal part of transmembrane helix M3 of theNa⁺,K⁺-ATPase. Journal of Biological Chemistry, 278, 38653-38664.

Toustrup-Jensen, M. S. & Vilsen, B. (2002). Importance of Glu282 in transmembrane segment M3 of the Na⁺,K⁺-ATPase for control of cation interaction and conformational changes. Journal of Biological Chemistry, 277, 38607-38617.

Toustrup-Jensen, M. S. & Vilsen, B. (2003). Importance of conserved Thr²¹⁴ in domain A of the Na⁺,K⁺-ATPase for stabilization of the phosphoryl transition state complex in E₂P phosphorylation. Journal of Biological Chemistry, 278, 11402-11410.

Toustrup-Jensen, M. S., Holm, R., Einholm, A. P., Schack, V. R., Morth, J. P., Nissen, P., Andersen, J. P. & Vilsen, B. (2009). The C Terminus of Na+,K+-ATPase Controls Na+ Affinity on Both Sides of the Membrane through Arg935. Journal of Biological Chemistry, 284(28), 18715-18725.

Toustrup-Jensen, M. S., Einholm, A. P., Schack, V., Nielsen, H. N., Holm, R., Sobrido, M.-J., Andersen, J. P., Clausen, T. & Vilsen, B. (2014). Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. Journal of Biological Chemistry, 289(6), 3186-3197.

Toustrup, L. B., Zhou, Y., Kvistgaard, H., Gregersen, N., Rittig, S., Aagaard, L., Corydon, T. J., Luo, Y. & Christensen, J. H. (2017). Induced pluripotent stem cells derived from a patient with autosomal dominant familial neurohypophyseal diabetes insipidus caused by a variant in the AVP gene. Stem Cell Research, 19, 37-42. https://doi.org/10.1016/j.scr.2016.12.021

Toustrup, L. B., Kvistgaard, H., Palmfeldt, J., Bjerre, C. K., Gregersen, N., Rittig, S., Corydon, T. J. & Christensen, J. H. (2018). The Novel Ser18del AVP Variant Causes Inherited Neurohypophyseal Diabetes Insipidus by Mechanisms Shared with Other Signal Peptide Variants. Neuroendocrinology, 106(2), 167–186. https://doi.org/10.1159/000477246

Toussaint, L., Indelicato, D. J., Stokkevåg, C. H., Lassen, Y. A., Pedro, C., Mikkelsen, R., Di Pinto, M., Li, Z., Flampouri, S., Vestergaard, A., Petersen, J. B. B., Schrøder, H., Høyer, M. & Muren, L. P. (2019). Radiation doses to brain substructures associated with cognition in radiotherapy of pediatric brain tumors. Acta Oncologica, 58(10), 1457-1462. https://doi.org/10.1080/0284186X.2019.1629014

Toussaint, L., Indelicato, D. J., Muren, L. P., Li, Z., Lassen-Ramshad, Y., Kirby, K., Pedro, C., Mikkelsen, R., Di Pinto, M., Høyer, M. & Stokkevåg, C. H. (2020). Temporal lobe sparing radiotherapy with photons or protons for cognitive function preservation in paediatric craniopharyngioma. Radiotherapy and Oncology, 142, 140-146. https://doi.org/10.1016/j.radonc.2019.08.002

Toussaint, L., Indelicato, D. J., Muren, L. P., Li, Z., Lassen, Y. A., Kirby, K., Pedro, C., Mikkelsen, R., Di Pinto, M., Høyer, M. & Stokkevåg, C. H. (2021). Response to: 'Comments on "Temporal lobe sparing radiotherapy with photons or protons for cognitive function preservation in paediatric craniopharyngioma" by Toussaint, et al.: Prior similar field arrangement work and a need for variable RBE Use'. Radiotherapy & Oncology, 158, 330-331. https://doi.org/10.1016/j.radonc.2021.01.025

Tougaard, B. G., Laursen, K. S., Jensen, J. D. & Buus, N. H. (2020). Comparison of self- and nurse-measured office blood pressure in patients with chronic kidney disease. Blood Pressure Monitoring, 25(5), 237-241. https://doi.org/10.1097/MBP.0000000000000453

Tøttrup, M., Forsingdal Hardlei, T., Bendtsen, M., Bue, M., Brock, B., Fuursted, K., Søballe, K. & Birke-Sørensen, H. (2014). Pharmacokinetics of Cefuroxime in Cortical and Cancellous Bone Obtained by Microdialysis - a Porcine Study. Antimicrobial Agents and Chemotherapy, 58(6), 3200-3205. https://doi.org/10.1128/AAC.02438-14

Tóth, A. & Nielsen, M. S. (2018). Analysis of the trafficking system in blood-brain barrier models by high content screening microscopy. Neural Regeneration Research, 13(11), 1883.

Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S. (2018). The Endo-Lysosomal System of Brain Endothelial Cells Is Influenced by Astrocytes In Vitro. Molecular Neurobiology, 55(11), 8522-8537. https://doi.org/10.1007/s12035-018-0988-x

Toth, A. E., Nielsen, S. S. E., Tomaka, W., Abbott, N. J. & Nielsen, M. S. (2019). The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells. Fluids and Barriers of the CNS, 16(1), Artikel 14. https://doi.org/10.1186/s12987-019-0134-9

Toth, A. E., Holst, M. R. & Nielsen, M. S. (2020). Vesicular Transport Machinery in Brain Endothelial Cells: What We Know and What We Do Not. Current Pharmaceutical Design, 26(13), 1405-1416. https://doi.org/10.2174/1381612826666200212113421

Toth, A. E., Helms, H. C., Harazin, A., Johnsen, K. B., Goldeman, C., Burkhart, A., Thomsen, M. S., Kempen, P. J., Klepe, A., Lipka, D. V., Møller, P. L., Andresen, T. L., Nyegaard, M., Moos, T., Brodin, B. & Nielsen, M. S. (2022). Sortilin regulates blood-brain barrier integrity. FEBS journal, 289(4), 1062-1079. https://doi.org/10.1111/febs.16225

Toth, A. E. & Nielsen, M. S. (2023). Sortilins in the blood-brain barrier: impact on barrier integrity. Neural Regeneration Research, 18(3), 549-550. https://doi.org/10.4103/1673-5374.350197

Toth, A. E., Klepe, A., Lipka, D. V., Goldeman, C., Brodin, B. & Nielsen, M. S. (2022). SorLA in astrocytes regulates blood-brain barrier integrity. Frontiers in Drug Delivery, 2, Artikel 1082689. https://doi.org/10.3389/fddev.2022.1082689

Torvund-Jensen, J., Steengaard, J., Reimer, L., Fihl, L. B. & Laursen, L. S. (2014). Transport and translation of MBP mRNA is regulated differently by distinct hnRNP proteins. Journal of Cell Science, 127(Pt 7), 1550-1564. https://doi.org/10.1242/jcs.140855

Tørring, N., Dagnæs-Hansen, F., Sørensen, B. S., Ørntoft, T. F. & Nexø, E. (2005). Increase in amphiregulin and epiregulin in prostate cancer xenograft after androgen deprivation-impact of specific HER1 inhibition. Prostate, 64(1), 1-8.

Tørring, M., Jensen, K. H., Hessellund, A., Aalkjær, C. & Bek, T. (2009). The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition. Investigative Ophthalmology & Visual Science, 50(1), 345-51.

Tørring, C. W., Petersen, C. C., Bjerg, L., Kofod-Olsen, E., Petersen, T. & Höllsberg, P. (2013). The B1-cell subpopulation is diminshed in patients with relapsing-remitting multiple sclerosis. Journal of Neuroimmunology, 262, 92-99.

Tørring, C. W., Andreasen, C., Gehr, N., Hansen, L. B., Petersen, T. & Höllsberg, P. (2014). Higher incidence of Epstein-Barr virus-induced lymphocyte transformation in multiple sclerosis. Acta Neurologica Scandinavica, 130(2), 90-96. https://doi.org/10.1111/ane.12249

Tørring, N., Petersen, O. B., Becher, N., Vogel, I., Uldbjerg, N. & the Danish Fetal Medicine Study Group (2015). First trimester screening for other trisomies than trisomy 21, 18 and 13. Prenatal Diagnosis, 35(6), 612-19. https://doi.org/10.1002/pd.4584

Torring, M. S., Aalkjaer, C. & Bek, T. (2014). Constriction of porcine retinal arterioles induced by endothelin-1 and the thromboxane analogue U46619 in vitro decreases with increasing vascular branching level. Acta Ophthalmologica, 92(3), 232-7. https://doi.org/10.1111/aos.12143

Torres, Y. P., Morera, F. J., Carvacho, I. & Latorre, R. (2007). A marriage of convenience: beta-subunits and voltage-dependent K+ channels. Journal of Biological Chemistry, 282(34), 24485-9. Artikel 17606609.

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