Peer-reviewed publikationer

Peer-reviewed publications

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Vad-Nielsen, J., Lin, L., Jensen, K. T., Nielsen, A. L. & Luo, Y. (2016). A Golden Gate-based Protocol for Assembly of Multiplexed gRNA Expression Arrays for CRISPR/Cas9. Bio-protocol, 6(23), Artikel e2059. https://doi.org/10.21769/BioProtoc.2059

Vad-Nielsen, J., Nielsen, A. L. & Luo, Y. (2018). Simple method for assembly of CRISPR synergistic activation mediator gRNA expression array. Journal of Biotechnology, 274, 54-57. https://doi.org/10.1016/j.jbiotec.2018.03.018

Vad-Nielsen, J., Gammelgaard, K. R., Daugaard, T. F. & Nielsen, A. L. (2019). Cause-and-Effect relationship between FGFR1 expression and epithelial-mesenchymal transition in EGFR-mutated non-small cell lung cancer cells. Lung Cancer, 132, 132-140. https://doi.org/10.1016/j.lungcan.2019.04.023

Vad-Nielsen, J., Meldgaard, P., Sorensen, B. S. & Nielsen, A. L. (2020). Cell-free Chromatin Immunoprecipitation (cfChIP) from blood plasma can determine gene-expression in tumors from non-small-cell lung cancer patients. Lung Cancer, 147, 244-251. https://doi.org/10.1016/j.lungcan.2020.07.023

Vad-Nielsen, J., Staunstrup, N. H., Kjeldsen, M. L., Dybdal, N., Flandin, G., De Stradis, C., Daugaard, T. F., Vilsbøll-Larsen, T., Maansson, C. T., Doktor, T. K., Sorensen, B. S. & Nielsen, A. L. (2023). Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells. Translational Lung Cancer Research, 12(1), 42-65. https://doi.org/10.21037/tlcr-22-507

Uzureau, P., Uzureau, S., Lecordier, L., Fontaine, F., Tebabi, P., Homblé, F., Grélard, A., Zhendre, V., Nolan, D. P., Lins, L., Crowet, J.-M., Pays, A., Felu, C., Poelvoorde, P., Vanhollebeke, B., Moestrup, S. K., Lyngsø, J., Pedersen, J. S., Mottram, J. C. ... Pays, E. (2013). Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature, 501(7467), 430-4. https://doi.org/10.1038/nature12516

Uzureau, S., Lecordier, L., Uzureau, P., Hennig, D., Graversen, J. H., Homblé, F., Mfutu, P. E., Oliveira Arcolino, F., Ramos, A. R., La Rovere, R. M., Luyten, T., Vermeersch, M., Tebabi, P., Dieu, M., Cuypers, B., Deborggraeve, S., Rabant, M., Legendre, C., Moestrup, S. K. ... Pays, E. (2020). APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin. Cell Reports, 30(11), 3821-3836.e13. https://doi.org/10.1016/j.celrep.2020.02.064

Uzgün, S., Akdemir, O., Hasenpusch, G., Maucksch, C., Golas, M. M., Sander, B., Stark, H., Imker, R., Lutz, J.-F. & Rudolph, C. (2010). Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: influence of macromolecular structure on gene vector particle properties and transfection efficiency. Biomacromolecules, 11(1), 39-50. https://doi.org/10.1021/bm9008759

Uwera, J., Nedergaard, S. T. & Andreasen, M. (2015). A novel mechanism for the anticonvulsant effect of furosemide in rat hippocampus in vitro. Brain Research, 1625, 1-8.

Uriarte, M., De Francesco, P. N., Fernández, G., Castrogiovanni, D., D'Arcangelo, M., Imbernon, M., Cantel, S., Denoyelle, S., Fehrentz, J. A., Praetorius, J., Prevot, V. & Perello, M. (2021). Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms. Molecular and Cellular Endocrinology, 538, Artikel 111449. https://doi.org/10.1016/j.mce.2021.111449

Urbschat, A., Stumpf, S., Hänze, J., Paulus, P., Maier, T. J., Weipert, C., Hofmann, R. & Hegele, A. (2016). Expression of the anti-inflammatory suppressor of cytokine signaling 3 (SOCS3) in human clear cell renal cell carcinoma. Tumor Biology, 37(7), 9649-9656. https://doi.org/10.1007/s13277-016-4857-9

Urbschat, A., Baer, P., Zacharowski, K., Sprunck, V., Scheller, B., Raimann, F., Maier, T. J., Hegele, A., Hofmann, R. & Mersmann, J. (2018). Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney. Basic & Clinical Pharmacology & Toxicology, 122(2), 223-232. https://doi.org/10.1111/bcpt.12896

Urbschat, A. E., Nielsen, T. K., Nielsen, R. & Maier, T. J. (2019). Effect of nitro fatty acids in LPS challenged primary human renal tubular epithelial cells.

Urbschat, A., Thiemens, A. K., Mertens, C., Rehwald, C., Meier, J. K., Baer, P. C. & Jung, M. (2020). Macrophage-secreted lipocalin-2 promotes regeneration of injured primary murine renal tubular epithelial cells. International Journal of Molecular Sciences , 21(6), Artikel 2038. https://doi.org/10.3390/ijms21062038

Urbonavicius, S., Vorum, H., Urbonaviciene, G., Trumpickas, M., Pavalkis, D. & Honore, B. (2005). Predictors of post-operative mortality following treatment for non-ruptured abdominal aortic aneyrysm. Trials, 6, 14.

Urbonavicius, S., Heegaard, N. H., Honore, B., Vorum, H. & Lindholt, J. S. (2006). Autoantibodies in cases with abdominal aortic aneurysms are seldom and without association with progression rate. E J V E S Extra, 12, 13-14.

Urbonavicius, S., Lindholt, J. S., Vorum, H., Urbonaviciene, G., Henneberg, E. W. & Honoré, B. (2009). Proteomic identification of differentially expressed proteins in aortic wall of patients with ruptured and nonruptured abdominal aortic aneurysms. Journal of Vascular Surgery, 49, 455-463.

Urbonavicius, S., Urbonaviciene, G., Honoré, B., Henneberg, E. W., Vorum, H. & Lindholt, J. S. (2008). Potential circulating biomarkers for abdominal aortic aneurysm expansion and rupture--a systematic review. European Journal of Vascular and Endovascular Surgery, 36(3), 273-80; discussion 281-2. https://doi.org/10.1016/j.ejvs.2008.05.009

Urbonavicius, S., Wiggers, H., Bøtker, H. E., Nielsen, T. T., Kimose, H. H., Østergaard, M., Lindholt, J. S., Vorum, H. & Honoré, B. (2009). Proteomic analysis identifies mitochondrial metabolic enzymes as major discriminators between different stages of the failing human myocardium. Acta Cardiologica, 64(4), 511-22.

Urbonavicius, S., Lindholt, J. S., Delbosc, S., Urbonaviciene, G., Henneberg, E. W., Vorum, H., Meilhac, O. & Honoré, B. (2010). Proteins associated with the size and expansion rate of the abdominal aortic aneurysm wall as identified by proteomic analysis. Interactive Cardiovascular and Thoracic Surgery, 11(4), 433-41. https://doi.org/10.1510/icvts.2010.238139

Urbonaviciene, G., Urbonavicius, S., Vorum, H., Bluzaite, I., Jarusevicius, G., Honoré, B. & Tamosiunaite, M. (2008). Evaluation of prognostic clinical and ECG parameters in patients after myocardial infarction by applying logistic regression method. Pacing and Clinical Electrophysiology, 31, 1391-1398.

Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G. (2010). IFI16 is an innate immune sensor for intracellular DNA. Nature Immunology, 11(11), 997-1004. https://doi.org/10.1038/ni.1932

Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Ng, D. P. K., Holmkvist, J., Borch-Johnsen, K., Jørgensen, T., Sandbaek, A., Lauritzen, T., Hansen, T., Nurbaya, S., Tsunoda, T., Kubo, M., Babazono, T., Hirose, H., Hayashi, M., Iwamoto, Y. ... Maeda, S. (2008). SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nature Genetics, 40(9), 1098-102. https://doi.org/10.1038/ng.208

Underhaug, J., Jakobsen, L. O., Esmann, M., Malmendal, A. & Nielsen, N. C. (2006). NMR studies of the fifth transmembrane segment of Na⁺,K⁺-ATPase reveals a non-helical ion-binding region. FEBS Letters, 580, 4777-4783.

Underbjerg, M., Kesmodel, U. S., Landrø, N. I., Bakketeig, L. S., Grove, J., Wimberley, T., Kilburn, T. R., Sværke, C., Thorsen, P. & Mortensen, E. L. (2012). The Effects of Low to Moderate Alcohol Consumption and Binge Drinking in Early Pregnancy on Selective and Sustained Attention in Five-Year-Old Children. B J O G, 119(10), 1211-1221. https://doi.org/10.1111/j.1471-0528.2012.03396.x

Ulusoy, A., Febbraro, F., Jensen, P. H., Kirik, D. & Romero-Ramos, M. (2010). Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology. European Journal of Neuroscience, 32(3), 409-22. https://doi.org/10.1111/j.1460-9568.2010.07284.x

Ulrik, M. G., Pujolar, J. M., Ferchaud, A.-L., Jacobsen, L. M. W., Als, T. D., Gagnaire, P. A., Frydenberg, J., Bøcher, P. K., Jonsson, B., Bernatchez, L. & Hansen, M. M. (2014). Do North Atlantic eels show parallel patterns of spatially varying selection? BMC Evolutionary Biology, 14, Artikel 138. https://doi.org/10.1186/1471-2148-14-138

Ulrich-Vinther, M. & Andreassen, T. T. (2005). Osteoprotegerin treatment impairs remodeling and apparent material properties of callus tissue without influencing structural fracture strength. Calcif. Tissue Int., 76(4), 280-286.

Ulrich-Vinther, M., Schwarz, E. M., Pedersen, F. S., Søballe, K. & Andreassen, T. T. (2005). Gene therapy with human osteoprotegerin decreases callus remodelling with limited effects on biomechanical properties. Bone, 37(6), 751-758. https://doi.org/10.1016/j.bone.2005.07.021

Ulrichsen, M., Gonçalves, N. P., Mohseni, S., Hjæresen, S., Lisle, T. L., Molgaard, S., Madsen, N. K., Andersen, O. M., Svenningsen, Å. F., Glerup, S., Nykjær, A. & Vægter, C. B. (2022). Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury. Frontiers in Cellular Neuroscience, 16, Artikel 856734. https://doi.org/10.3389/fncel.2022.856734

Ulmsten, U., Andersson, K. E. & Forman, A. (1978). Relaxing effects of Nifedipine on the nonpregnant human uterus in vitro and in vivo. Obstetrics and Gynecology, 52(4), 436-41.

Uldbjerg, N. & Danielsen, C. C. (1988). A study of the interaction in vitro between type I collagen and a small dermatan sulphate proteoglycan. Biochemical Journal, 251(3), 643-8.

Uldbjerg, N., Singh, R., Hatt, L., Vestergaard, E. M., Vogel, I., Christensen, R., Schelde, P. & Kølvrå, S. (2016). Cell based Non‐invasive Prenatal Testing (NIPT). Abstract fra The 40th Nordic Congress of Obstetrics and Gynecology, Helsinki, Finland.

Uldbjerg, N., Singh, R., Christensen, R., Schelde, P., Vogel, I., Hatt, L. & Kølvraa, S. (2016). Cell-baswd non-invasive prenatal testing. Abstract fra 26th World Congress on Ultrasound in Obstetrics and Gynecology, Rome, Italien.

Uldbjerg, C. S., Miller, J. E., Burgner, D., Pedersen, L. H. & Bech, B. H. (2021). Antibiotic exposure during pregnancy and childhood asthma: a national birth cohort study investigating timing of exposure and mode of delivery. Archives of Disease in Childhood, 106(9), 888-894. https://doi.org/10.1136/archdischild-2020-319659

Ulbrich, C., Westphal, K., Baatout, S., Wehland, M., Bauer, J., Flick, B., Infanger, M., Kreutz, R., Vadrucci, S., Egli, M., Cogoli, A., Derradji, H., Pietsch, J., Paul, M. & Grimm, D. (2008). Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity. Journal of Cellular Biochemistry, 104(4), 1324-41. https://doi.org/10.1002/jcb.21710

Ulbrich, C., Westphal, K., Pietsch, J., Winkler, H. D. F., Leder, A., Bauer, J., Kossmehl, P., Grosse, J., Schoenberger, J., Infanger, M., Egli, M. & Grimm, D. (2010). Characterization of human chondrocytes exposed to simulated microgravity. Cellular Physiology and Biochemistry, 25(4-5), 551-60. https://doi.org/10.1159/000303059

Ulbrich, C., Leder, A., Pietsch, J., Flick, B., Wehland, M. & Grimm, D. G. (2010). The impact of vascular endothelial growth factor and basic fibroblast growth factor on cardiac fibroblasts grown under altered gravity conditions. Cellular Physiology and Biochemistry, 26(6), 1011-22. https://doi.org/10.1159/000323976

Ulbrich, C., Pietsch, J., Grosse, J., Wehland, M., Schulz, H., Saar, K., Hübner, N., Hauslage, J., Hemmersbach, R., Braun, M., van Loon, J., Vagt, N., Egli, M., Richter, P., Einspanier, R., Sharbati, S., Baltz, T., Infanger, M., Ma, X. & Grimm, D. (2011). Differential Gene Regulation under Altered Gravity Conditions in Follicular Thyroid Cancer Cells: Relationship between the Extracellular Matrix and the Cytoskeleton. Cellular Physiology and Biochemistry, 28(2), 185-98. https://doi.org/10.1159/000331730

Ulbrich, C., Wehland, M., Pietsch, J., Aleshcheva, G., Wise, P., van Loon, J., Magnusson, N., Infanger, M., Grosse, J., Eilles, C., Sundaresan, A. & Grimm, D. (2014). The impact of simulated and real microgravity on bone cells and mesenchymal stem cells. BioMed Research International, 2014, Artikel 928507. https://doi.org/10.1155/2014/928507

Uhrenholt, L., Ullerup, R., Vesterby, A. & Gregersen, M. E. G. (2006). Examination of Cervical Spine Histological Sections - A Technical Note. The Journal of Whiplash & Related Disorders, 5(1), 55-60.

Uemura, K., Saka, M., Nakagawa, T., Kawasaki, N., Thiel, S., Jensenius, J. C. & Kawasaki, T. (2002). L-MBP is expressed in epithelial cells of mouse small intestine. Journal of Immunology, 169(12), 6945-50.

Uemura, T., Lee, S.-J., Yasumura, M., Takeuchi, T., Yoshida, T., Ra, M., Taguchi, R., Sakimura, K. & Mishina, M. (2010). Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum. Cell, 141(6), 1068-79. https://doi.org/10.1016/j.cell.2010.04.035

Ueland, T., Ebbesen, E. N., Thomsen, J. S., Mosekilde, L., Brixen, K., Flyvbjerg, A. & Bollerslev, J. (2002). Decreased trabecular bone biomechanical competence, apparent density, IGF-II and IGFBP-5 content in acromegaly. European Journal of Clinical Investigation, 32(2), 122-128. https://doi.org/10.1046/j.1365-2362.2002.00944.x

Uchiyama, K., Tomita, M., Yano, M., Chida, J., Hara, H., Das, N. R., Nykjaer, A. & Sakaguchi, S. (2017). Prions amplify through degradation of the VPS10P sorting receptor sortilin. P L o S Pathogens, 13(6), e1006470. Artikel e1006470. https://doi.org/10.1371/journal.ppat.1006470

Ubhi, K., Rockenstein, E., Kragh, C., Inglis, C., Spencer, B., Michael, S., Mante, M., Adame, A., Galasko, D. & Masliah, E. (2013). Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. The European journal of neuroscience. https://doi.org/10.1111/ejn.12444

Tvilling, L., Glud, A. N., Jan, J., Orlowski, D., Ettrup, K. S., Bender, D., Petersen, M., Bjarkam, C., West, M. J. & Sorensen, J. C. (2016). The anatomy and neurohistology of the minipig pituitary. Poster session præsenteret på Neuroscience Day 2016, Aarhus, Danmark.

Tveden-Nyborg, P., Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, J. (2021). BCPT policy for experimental and clinical studies. Basic & Clinical Pharmacology & Toxicology, 128(1), 4-8. https://doi.org/10.1111/bcpt.13492

Tveden-Nyborg, P., Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, J. (2023). BCPT 2023 policy for experimental and clinical studies. Basic and Clinical Pharmacology and Toxicology, 133(4), 391-396. https://doi.org/10.1111/bcpt.13944

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Revideret 14.09.2020