Thomsen, M. M., Skouboe, M. K., Møhlenberg, M., Zhao, J., de Keukeleere, K., Heinz, J. L., Werner, M., Hollensen, A. K., Lønskov, J., Nielsen, I., Carter-Timofte, M. E., Zhang, B., Mikkelsen, J. G., Fisker, N.
, Paludan, S. R., Assing, K.
& Mogensen, T. H. (2024).
Impaired STING Activation Due to a Variant in the E3 Ubiquitin Ligase AMFR in a Patient with Severe VZV Infection and Hemophagocytic Lymphohistiocytosis.
Journal of Clinical Immunology,
44(2), Artikel 56.
https://doi.org/10.1007/s10875-024-01653-5
Thomsen, S. H., Lund, I. C. B., Bache, I.
, Becher, N. & Vogel, I. (2024).
Placental mosaicism for autosomal trisomies: comprehensive follow-up of 528 Danish cases (1983–2021).
American Journal of Obstetrics and Gynecology MFM,
6(11), Artikel 101497.
https://doi.org/10.1016/j.ajogmf.2024.101497
Thomsen, A. K., Steffensen, M. A., Villarruel Hinnerskov, J. M., Nielsen, A. T., Vorum, H.
, Honoré, B., Nissen, M. H. & Sørensen, T. L. (2024).
Complement proteins and complement regulatory proteins are associated with age-related macular degeneration stage and treatment response.
Journal of Neuroinflammation,
21(1), Artikel 284.
https://doi.org/10.1186/s12974-024-03273-7
Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C. ... the Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group (2014).
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
Brain Imaging and Behavior.
https://doi.org/10.1007/s11682-013-9269-5
Thomassen, M.
, Hansen, T. V. O., Borg, A., Lianee, H. T.
, Wikman, F., Pedersen, I. S., Bisgaard, M. L., Nielsen, F. C., Kruse, T. A. & Gerdes, A.-M. (2008).
BRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer. Acta Oncologica,
47(4), 772-7.
https://doi.org/10.1080/02841860802004974
Thomassen, M.
, Pedersen, I. S., Vogel, I., Hansen, T. V. O., Brasch-Andersen, C., Brasen, C. L., Crüger, D.
, Sunde, L., Nielsen, F. C.
, Jensen, U. B., Bisgaard, M. L., Borg, Å., Gerdes, A.-M. & Kruse, T. A. (2011).
A BRCA2 mutation incorrectly mapped in the original BRCA2 reference sequence, is a common West Danish founder mutation disrupting mRNA splicing.
Breast Cancer Research and Treatment,
128 (1), 179-85.
https://doi.org/10.1007/s10549-010-1272-6
Thomassen, M., Blanco, A., Montagna, M., Hansen, T. V. O.
, Pedersen, I. S., Gutiérrez-Enríquez, S., Menéndez, M., Fachal, L., Santamariña, M., Steffensen, A. Y., Jønson, L., Agata, S., Whiley, P., Tognazzo, S., Tornero, E.
, Jensen, U. B., Balmaña, J., Kruse, T. A., Goldgar, D. E. ... Vega, A. (2012).
Characterization of BRCA1 and BRCA2 splicing variants: a collaborative report by ENIGMA consortium members.
Breast Cancer Research and Treatment,
132(3), 1009-23.
https://doi.org/10.1007/s10549-011-1674-0
Thomasen, P. B., Salasova, A., Kjaer-Sorensen, K., Woloszczuková, L., Lavický, J.
, Login, H., Tranberg-Jensen, J., Almeida, S., Beel, S., Kavková, M.
, Qvist, P., Kjolby, M., Ovesen, P. L., Nolte, S., Vestergaard, B., Udrea, A.-C., Nejsum, L. N., Chao, M. V., Van Damme, P.
... Nykjaer, A. (2023).
SorCS2 binds progranulin to regulate motor neuron development.
Cell Reports,
42(11), Artikel 113333.
https://doi.org/10.1016/j.celrep.2023.113333
Thomas, A. C., Williams, H., Setõ-Salvia, N., Bacchelli, C., Jenkins, D., O'Sullivan, M., Mengrelis, K., Ishida, M., Ocaka, L., Chanudet, E., James, C.
, Lescai, F., Anderson, G., Morrogh, D., Ryten, M., Duncan, A. J., Pai, Y. J., Saraiva, J. M., Ramos, F. ... Stanier, P. (2014).
Mutations in SNX14 cause a distinctive autosomal-recessive cerebellar ataxia and intellectual disability syndrome.
American Journal of Human Genetics,
95(5), 611-621.
https://doi.org/10.1016/j.ajhg.2014.10.007
Thomas, L., Xue, J.
, Murali, S. K., Fenton, R. A., Dominguez Rieg, J. A. & Rieg, T. (2019).
Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function.
Journal of the American Society of Nephrology : JASN,
30(11), 2128-2139.
https://doi.org/10.1681/ASN.2018121250
Thomas, L., Xue, J.
, Murali, S. K., Fenton, R. A., Rieg, J. A. D. & Rieg, T. (2019).
Npt2a inhibition in chronic kidney disease.
Acta Physiologica,
227.
https://doi.org/10.1111/apha.13366
Thisted, D. L. A., Østergaard, M. V., Pedersen, A. A., Pedersen, P. J., Lindsay, R. T., Murray, A. J., Fink, L. N., Pedersen, T. X., Secher, T.
, Johansen, T. T., Thrane, S. T., Skarsfeldt, T., Jelsing, J., Thomsen, M. B. & Zois, N. E. (2020).
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Scientific Reports,
10(1), Artikel 16130.
https://doi.org/10.1038/s41598-020-73046-8
Thingholm, L. B., Andersen, L., Makalic, E., Southey, M. C., Thomassen, M.
& Hansen, L. L. (2016).
Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges.
Frontiers in Genetics,
7(FEB), 1-13. Artikel 2.
Thinggaard, L. B., Su, J., Comerma Steffensen, S. G., Pinilla, E., Carlsson, R. F., Hernanz, R., Sheykhzade, M.
, Danielsen, C. C. & Simonsen, U. (2020).
Endothelial Dysfunction and Passive Changes in the Aorta and Coronary Arteries of Diabetic db/db Mice.
Frontiers in Physiology,
11, Artikel 667.
https://doi.org/10.3389/fphys.2020.00667
Thinggaard, L. B., Pinilla, E., Arcanjo, D. D. R., Hernanz, R., Prat Duran, J., Petersen, A., Köhler, R., Sheykhzade, M.
, Comerma Steffensen, S. G. & Simonsen, U. (2021).
Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice.
Frontiers in Pharmacology,
11, Artikel 619152.
https://doi.org/10.3389/fphar.2020.619152
Thim-uam, A.
, Prabakaran, T., Tansakul, M., Makjaroen, J., Wongkongkathep, P., Chantaravisoot, N., Saethang, T., Leelahavanichkul, A., Benjachat, T.
, Paludan, S., Pisitkun, T. & Pisitkun, P. (2020).
STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation.
iScience,
23(9), Artikel 101530.
https://doi.org/10.1016/j.isci.2020.101530
Thim, T., Bentzon, J. F., Kristiansen, S. B., Simonsen, U., Andersen, H. L., Wassermann, K.
& Falk, E. (2006).
Size of myocardial infarction induced by ischaemia/reperfusion is unaltered in rats with metabolic syndrome.
Clin. Sci.,
110(6), 665-71.
Thienel, M., Müller-Reif, J. B., Zhang, Z., Ehreiser, V., Huth, J., Shchurovska, K., Kilani, B., Schweizer, L., Geyer, P. E., Zwiebel, M., Novotny, J., Lüsebrink, E., Little, G., Orban, M., Nicolai, L., El Nemr, S., Titova, A., Spannagl, M., Kindberg, J. ... Petzold, T. (2023).
Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
Science,
380(6641), 178-187.
https://doi.org/10.1126/science.abo5044
Thielsen, K. D., Moser, J. M., Schmitt-John, T., Jensen, M. S., Jensen, K. & Holm, M. M. (2013).
The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments.
P L o S One,
8(12)(e82767).
Thielens, N. M., Cseh, S.
, Thiel, S., Vorup-Jensen, T., Rossi, V.
, Jensenius, J. C. & Arlaud, G. J. (2001).
Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL.
Journal of Immunology,
166(8), 5068-77.
Thiele, L. S., Ishtiak-Ahmed, K., Thirstrup, J. P., Agerbo, E., Lunenburg, C. A. T. C., Müller, D. J.
& Gasse, C. (2022).
Clinical Impact of Functional CYP2C19 and CYP2D6 Gene Variants on Treatment with Antidepressants in Young People with Depression: A Danish Cohort Study.
Pharmaceuticals,
15(7), Artikel 870.
https://doi.org/10.3390/ph15070870
Thiel, S., Vorup-Jensen, T., Stover, C. M., Schwaeble, W., Laursen, S. B.
, Poulsen, K., Willis, A. C., Eggleton, P., Hansen, S., Holmskov, U., Reid, K. B.
& Jensenius, J. C. (1997).
A second serine protease associated with mannan-binding lectin that activates complement.
Nature,
386, 506-10.
Thiel, S., Steffensen, R. N., Christensen, I. J., Ip, WK., Lau, YL., Reason, IJ., Eiberg, H., Gadjeva, M., Ruseva, M.
& Jensenius, J. C. (2007).
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms. Genes and Immunity,
8(2), 154-163.
Thiel, S., Petersen, S. V., Vorup-Jensen, T., Matsushita, M.
, Fujita, T., Stover, C. M., Schwaeble, W. J.
& Jensenius, J. C. (2000).
Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19. Journal of Immunology,
165(2), 878-87.
Thiel, S., Kolev, M.
, Degn, S. E., Steffensen, R., Hansen, A., Ruseva, M.
& Jensenius, J. C. (2009).
Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity.
Journal of Immunology,
182(5), 2939-47.
https://doi.org/10.4049/jimmunol.0802053
Thiel, S., Bjerke, T., Hansen, D., Poulsen, L. K.
, Schiøtz, P. O. & Jensenius, J. C. (1995).
Ontogeny of human mannan-binding protein, a lectin of the innate immune system.
Pediatric Allergy and Immunology,
6(1), 20-3.
Thiel, S., Holmskov, U.
, Hviid, L., Laursen, S. B.
& Jensenius, J. C. (1992).
The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response.
Clinical and Experimental Immunology,
90(1), 31-5.
Thiel, S., Baatrup, G., Friis-Christiansen, P., Svehag, S. E.
& Jensenius, J. C. (1987).
Characterization of a lectin in human plasma analogous to bovine conglutinin.
Scandinavian Journal of Immunology,
26(5), 461-8.
Thiel, S., Steffensen, R., Christensen, I. J., Ip, W. K., Lau, Y. L., Reason, I. J. M., Eiberg, H. R. L., Gadjeva, M., Ruseva, M.
& Jensenius, J. C. (2007).
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms.
Genes and Immunity,
8(2), 154-63.
https://doi.org/10.1038/sj.gene.6364373
Thiel, S., Vorup-Jensen, T., Stover, C. M., Schwaeble, W., Laursen, S.
, Poulsen, K., Willis, A. C., Eggleton, P.
, Hansen, S., Holmskov, U. L., Reid, K. B.
& Jensenius, J. C. (1997).
A second serine protease associated with mannan-binding lectin that activates complement.
Nature,
386(6624), 506-10.
https://doi.org/10.1038/386506a0
Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J.
& Jensenius, J. C. (2012).
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
Clinical and Experimental Immunology. Supplement,
169(1), 38-48.
https://doi.org/10.1111/j.1365-2249.2012.04584.x
Therkildsen, N. O., Hemmer-Hansen, J.
, Als, T. D., Swain, D. P., Morgan, M. J., Trippel, E. A., Palumbi, S. R., Meldrup, D. & Nielsen, E. E. (2013).
Microevolution in time and space: SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod.
Molecular Ecology,
22(9), 2424-2440.
https://doi.org/10.1111/mec.12260
Therkildsen, C., Timshel, S., Nilbert, M. & HNPCC-gruppe: Henrik Okkels og Henrik Krarup, Klinisk Biokemisk Afdeling, Aalborg Sygehus; Friedrik Wikman og Torben F. Ørntoft, Klinisk Biokemisk Afdeling, Århus Universitetshospital, Skejby; Thomas v. O. Hansen og Finn C. Nielsen, Klinisk Biokemisk Afdeling, Rigshospitalet; Marie Luise Bisgaard, Institut for Cellulær og Molekylær Medicin, Københavns Universitet; Inge Bernstein, HNPCC-registret, Gastroenheden, Hvidovre Hospital; Lone Sunde, Klinisk Genetisk Afdeling, Århus Universitetshospital; Anne-Marie Gerdes, Afdeling for Biokemi, Farmakologi og Genetik, Odense Universitetssygehus; Dorthe Crüger, Klinisk Genetisk Afdeling, Vejle Sygehus (2008).
Indsigter og udfordringer i danske Lynch-syndrom-familier.
Ugeskrift for Læger,
170(25), 2252-5.
Therkildsen, J. R., Christensen, M. G., Tingskov, S. J., Wehmöller, J., Nørregaard, R. & Praetorius, H. A. (2019).
Lack of P2X
7
Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin–Producing Escherichia coli.
American Journal of Pathology,
189(6), 1201-1211.
https://doi.org/10.1016/j.ajpath.2019.02.013
Therkildsen, J., Rohde, P. D.
, Nissen, L., Thygesen, J., Hauge, E.-M., Langdahl, B. L., Boettcher, M., Nyegaard, M. & Winther, S. (2023).
A genome-wide genomic score added to standard recommended stratification tools does not improve the identification of patients with very low bone mineral density.
Osteoporosis International,
34(11), 1893-1906.
https://doi.org/10.1007/s00198-023-06857-w
Therkildsen, J. R., Tingskov, S. J., Jensen, M. S., Praetorius, H. & Nørregaard, R. (2023).
P2X7 accelerate tissue fibrosis via metalloproteinase 8-dependent macrophage infiltration in a murine model of unilateral ureteral obstruction.
Physiological Reports,
11(22), Artikel e15878.
https://doi.org/10.14814/phy2.15878
Therkildsen, J., Jensen, R. K., Hänel, M., Langdahl, B. L., Thygesen, J.
, Thomsen, J. S., Manske, S. L.
, Keller, K. K. & Hauge, E. M. (2025).
Erosive Progression by High-Resolution Peripheral Quantitative Computed Tomography and Conventional Radiography in Rheumatoid Arthritis.
Rheumatology,
64(3), 1092-1101. Artikel Online ahead of print.
https://doi.org/10.1093/rheumatology/keae281