Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C. ... the Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group (2014).
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
Brain Imaging and Behavior.
https://doi.org/10.1007/s11682-013-9269-5Thomassen, M.
, Hansen, T. V. O., Borg, A., Lianee, H. T.
, Wikman, F., Pedersen, I. S., Bisgaard, M. L., Nielsen, F. C., Kruse, T. A. & Gerdes, A.-M. (2008).
BRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer. Acta Oncologica,
47(4), 772-7.
https://doi.org/10.1080/02841860802004974Thomassen, M.
, Pedersen, I. S., Vogel, I., Hansen, T. V. O., Brasch-Andersen, C., Brasen, C. L., Crüger, D.
, Sunde, L., Nielsen, F. C.
, Jensen, U. B., Bisgaard, M. L., Borg, Å., Gerdes, A.-M. & Kruse, T. A. (2011).
A BRCA2 mutation incorrectly mapped in the original BRCA2 reference sequence, is a common West Danish founder mutation disrupting mRNA splicing.
Breast Cancer Research and Treatment,
128 (1), 179-85.
https://doi.org/10.1007/s10549-010-1272-6Thomassen, M., Blanco, A., Montagna, M., Hansen, T. V. O.
, Pedersen, I. S., Gutiérrez-Enríquez, S., Menéndez, M., Fachal, L., Santamariña, M., Steffensen, A. Y., Jønson, L., Agata, S., Whiley, P., Tognazzo, S., Tornero, E.
, Jensen, U. B., Balmaña, J., Kruse, T. A., Goldgar, D. E. ... Vega, A. (2012).
Characterization of BRCA1 and BRCA2 splicing variants: a collaborative report by ENIGMA consortium members.
Breast Cancer Research and Treatment,
132(3), 1009-23.
https://doi.org/10.1007/s10549-011-1674-0Thomasen, P. B., Salasova, A., Kjaer-Sorensen, K., Woloszczuková, L., Lavický, J.
, Login, H., Tranberg-Jensen, J., Almeida, S., Beel, S., Kavková, M.
, Qvist, P., Kjolby, M., Ovesen, P. L., Nolte, S., Vestergaard, B., Udrea, A.-C., Nejsum, L. N., Chao, M. V., Van Damme, P.
... Nykjaer, A. (2023).
SorCS2 binds progranulin to regulate motor neuron development.
Cell Reports,
42(11), Artikel 113333.
https://doi.org/10.1016/j.celrep.2023.113333
Thomas, A. C., Williams, H., Setõ-Salvia, N., Bacchelli, C., Jenkins, D., O'Sullivan, M., Mengrelis, K., Ishida, M., Ocaka, L., Chanudet, E., James, C.
, Lescai, F., Anderson, G., Morrogh, D., Ryten, M., Duncan, A. J., Pai, Y. J., Saraiva, J. M., Ramos, F. ... Stanier, P. (2014).
Mutations in SNX14 cause a distinctive autosomal-recessive cerebellar ataxia and intellectual disability syndrome.
American Journal of Human Genetics,
95(5), 611-621.
https://doi.org/10.1016/j.ajhg.2014.10.007Thomas, L., Xue, J.
, Murali, S. K., Fenton, R. A., Dominguez Rieg, J. A. & Rieg, T. (2019).
Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function.
Journal of the American Society of Nephrology : JASN,
30(11), 2128-2139.
https://doi.org/10.1681/ASN.2018121250Thomas, L., Xue, J.
, Murali, S. K., Fenton, R. A., Rieg, J. A. D. & Rieg, T. (2019).
Npt2a inhibition in chronic kidney disease.
Acta Physiologica,
227.
https://doi.org/10.1111/apha.13366Thisted, D. L. A., Østergaard, M. V., Pedersen, A. A., Pedersen, P. J., Lindsay, R. T., Murray, A. J., Fink, L. N., Pedersen, T. X., Secher, T.
, Johansen, T. T., Thrane, S. T., Skarsfeldt, T., Jelsing, J., Thomsen, M. B. & Zois, N. E. (2020).
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Scientific Reports,
10(1), Artikel 16130.
https://doi.org/10.1038/s41598-020-73046-8Thingholm, L. B., Andersen, L., Makalic, E., Southey, M. C., Thomassen, M.
& Hansen, L. L. (2016).
Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges.
Frontiers in Genetics,
7(FEB), 1-13. Artikel 2.
Thinggaard, L. B., Su, J., Comerma Steffensen, S. G., Pinilla, E., Carlsson, R. F., Hernanz, R., Sheykhzade, M.
, Danielsen, C. C. & Simonsen, U. (2020).
Endothelial Dysfunction and Passive Changes in the Aorta and Coronary Arteries of Diabetic db/db Mice.
Frontiers in Physiology,
11, Artikel 667.
https://doi.org/10.3389/fphys.2020.00667
Thinggaard, L. B., Pinilla, E., Arcanjo, D. D. R., Hernanz, R., Prat Duran, J., Petersen, A., Köhler, R., Sheykhzade, M.
, Comerma Steffensen, S. G. & Simonsen, U. (2021).
Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice.
Frontiers in Pharmacology,
11, Artikel 619152.
https://doi.org/10.3389/fphar.2020.619152
Thim-uam, A.
, Prabakaran, T., Tansakul, M., Makjaroen, J., Wongkongkathep, P., Chantaravisoot, N., Saethang, T., Leelahavanichkul, A., Benjachat, T.
, Paludan, S., Pisitkun, T. & Pisitkun, P. (2020).
STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation.
iScience,
23(9), Artikel 101530.
https://doi.org/10.1016/j.isci.2020.101530Thim, T., Bentzon, J. F., Kristiansen, S. B., Simonsen, U., Andersen, H. L., Wassermann, K.
& Falk, E. (2006).
Size of myocardial infarction induced by ischaemia/reperfusion is unaltered in rats with metabolic syndrome.
Clin. Sci.,
110(6), 665-71.
Thienel, M., Müller-Reif, J. B., Zhang, Z., Ehreiser, V., Huth, J., Shchurovska, K., Kilani, B., Schweizer, L., Geyer, P. E., Zwiebel, M., Novotny, J., Lüsebrink, E., Little, G., Orban, M., Nicolai, L., El Nemr, S., Titova, A., Spannagl, M., Kindberg, J. ... Petzold, T. (2023).
Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
Science,
380(6641), 178-187.
https://doi.org/10.1126/science.abo5044Thielsen, K. D., Moser, J. M., Schmitt-John, T., Jensen, M. S., Jensen, K. & Holm, M. M. (2013).
The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments.
PLoS One,
8(12)(e82767).
Thielens, N. M., Cseh, S.
, Thiel, S., Vorup-Jensen, T., Rossi, V.
, Jensenius, J. C. & Arlaud, G. J. (2001).
Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL.
Journal of Immunology,
166(8), 5068-77.
Thiele, L. S., Ishtiak-Ahmed, K., Thirstrup, J. P., Agerbo, E., Lunenburg, C. A. T. C., Müller, D. J.
& Gasse, C. (2022).
Clinical Impact of Functional CYP2C19 and CYP2D6 Gene Variants on Treatment with Antidepressants in Young People with Depression: A Danish Cohort Study.
Pharmaceuticals,
15(7), Artikel 870.
https://doi.org/10.3390/ph15070870
Thiel, S., Vorup-Jensen, T., Stover, C. M., Schwaeble, W., Laursen, S. B.
, Poulsen, K., Willis, A. C., Eggleton, P., Hansen, S., Holmskov, U., Reid, K. B.
& Jensenius, J. C. (1997).
A second serine protease associated with mannan-binding lectin that activates complement.
Nature,
386, 506-10.
Thiel, S., Steffensen, R. N., Christensen, I. J., Ip, WK., Lau, YL., Reason, IJ., Eiberg, H., Gadjeva, M., Ruseva, M.
& Jensenius, J. C. (2007).
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms. Genes and Immunity,
8(2), 154-163.
Thiel, S., Petersen, S. V., Vorup-Jensen, T., Matsushita, M.
, Fujita, T., Stover, C. M., Schwaeble, W. J.
& Jensenius, J. C. (2000).
Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19. Journal of Immunology,
165(2), 878-87.
Thiel, S., Kolev, M.
, Degn, S. E., Steffensen, R., Hansen, A., Ruseva, M.
& Jensenius, J. C. (2009).
Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity.
Journal of Immunology,
182(5), 2939-47.
https://doi.org/10.4049/jimmunol.0802053
Thiel, S., Bjerke, T., Hansen, D., Poulsen, L. K.
, Schiøtz, P. O. & Jensenius, J. C. (1995).
Ontogeny of human mannan-binding protein, a lectin of the innate immune system.
Pediatric Allergy and Immunology,
6(1), 20-3.
Thiel, S., Holmskov, U.
, Hviid, L., Laursen, S. B.
& Jensenius, J. C. (1992).
The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response.
Clinical and Experimental Immunology,
90(1), 31-5.
Thiel, S., Baatrup, G., Friis-Christiansen, P., Svehag, S. E.
& Jensenius, J. C. (1987).
Characterization of a lectin in human plasma analogous to bovine conglutinin.
Scandinavian Journal of Immunology,
26(5), 461-8.
Thiel, S., Steffensen, R., Christensen, I. J., Ip, W. K., Lau, Y. L., Reason, I. J. M., Eiberg, H. R. L., Gadjeva, M., Ruseva, M.
& Jensenius, J. C. (2007).
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms.
Genes and Immunity,
8(2), 154-63.
https://doi.org/10.1038/sj.gene.6364373
Thiel, S., Vorup-Jensen, T., Stover, C. M., Schwaeble, W., Laursen, S.
, Poulsen, K., Willis, A. C., Eggleton, P.
, Hansen, S., Holmskov, U. L., Reid, K. B.
& Jensenius, J. C. (1997).
A second serine protease associated with mannan-binding lectin that activates complement.
Nature,
386(6624), 506-10.
https://doi.org/10.1038/386506a0
Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J.
& Jensenius, J. C. (2012).
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
Clinical and Experimental Immunology. Supplement,
169(1), 38-48.
https://doi.org/10.1111/j.1365-2249.2012.04584.x
Therkildsen, N. O., Hemmer-Hansen, J.
, Als, T. D., Swain, D. P., Morgan, M. J., Trippel, E. A., Palumbi, S. R., Meldrup, D. & Nielsen, E. E. (2013).
Microevolution in time and space: SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod.
Molecular Ecology,
22(9), 2424-2440.
https://doi.org/10.1111/mec.12260Therkildsen, C., Timshel, S., Nilbert, M. & HNPCC-gruppe: Henrik Okkels og Henrik Krarup, Klinisk Biokemisk Afdeling, Aalborg Sygehus; Friedrik Wikman og Torben F. Ørntoft, Klinisk Biokemisk Afdeling, Århus Universitetshospital, Skejby; Thomas v. O. Hansen og Finn C. Nielsen, Klinisk Biokemisk Afdeling, Rigshospitalet; Marie Luise Bisgaard, Institut for Cellulær og Molekylær Medicin, Københavns Universitet; Inge Bernstein, HNPCC-registret, Gastroenheden, Hvidovre Hospital; Lone Sunde, Klinisk Genetisk Afdeling, Århus Universitetshospital; Anne-Marie Gerdes, Afdeling for Biokemi, Farmakologi og Genetik, Odense Universitetssygehus; Dorthe Crüger, Klinisk Genetisk Afdeling, Vejle Sygehus (2008).
Indsigter og udfordringer i danske Lynch-syndrom-familier.
Ugeskrift for Læger,
170(25), 2252-5.
Therkildsen, J. R., Christensen, M. G., Tingskov, S. J., Wehmöller, J., Nørregaard, R. & Praetorius, H. A. (2019).
Lack of P2X
7
Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin–Producing Escherichia coli.
American Journal of Pathology,
189(6), 1201-1211.
https://doi.org/10.1016/j.ajpath.2019.02.013
Therkildsen, J., Rohde, P. D.
, Nissen, L., Thygesen, J., Hauge, E.-M., Langdahl, B. L., Boettcher, M., Nyegaard, M. & Winther, S. (2023).
A genome-wide genomic score added to standard recommended stratification tools does not improve the identification of patients with very low bone mineral density.
Osteoporosis International,
34(11), 1893-1906.
https://doi.org/10.1007/s00198-023-06857-w
Therkildsen, J. R., Tingskov, S. J., Jensen, M. S., Praetorius, H. & Nørregaard, R. (2023).
P2X7 accelerate tissue fibrosis via metalloproteinase 8-dependent macrophage infiltration in a murine model of unilateral ureteral obstruction.
Physiological Reports,
11(22), Artikel e15878.
https://doi.org/10.14814/phy2.15878
Therkildsen, J., Jensen, R. K., Hänel, M., Langdahl, B. L., Thygesen, J.
, Thomsen, J. S., Manske, S. L.
, Keller, K. K. & Hauge, E. M. (2025).
Erosive Progression by High-Resolution Peripheral Quantitative Computed Tomography and Conventional Radiography in Rheumatoid Arthritis.
Rheumatology,
64(3), 1092-1101. Artikel Online ahead of print.
https://doi.org/10.1093/rheumatology/keae281
Therkildsen, J., Jensen, R. K., Hänel, M., Langdahl, B. L., Thomsen, J. S., Manske, S. L.
, Keller, K. K. & Hauge, E. M. (2025).
Detecting new erosions in rheumatoid arthritis over one year – Radiography and high-resolution computed tomography of finger joints.
Joint Bone Spine,
92(1), Artikel 105812.
https://doi.org/10.1016/j.jbspin.2024.105812