Peer-reviewed publications

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Hinrichs, G. R., Weyer, K., Friis, U. G., Svenningsen, P., Lund, I. K., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H. (2019). Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice. Acta Physiologica (Online), 227(4), Article e13362. https://doi.org/10.1111/apha.13362

Nykjaer, A., Petersen, C. M., Christensen, E. I., Davidsen, O. & Gliemann, J. (1990). Urokinase receptors in human monocytes. BBA General Subjects, 1052(3), 399-407.

Nykjaer, A., Møller, B. K., Todd, R. F., Christensen, T., Andreasen, P., Gliemann, J. & Petersen, C. M. (1994). Urokinase receptor. An activation antigen in human T lymphocytes. Journal of Immunology, 152(2), 505-16.

Jensen, P. H., Nykjaer, A., Andreasen, P. A., Lund, L., Astedt, B., Lecander, I. & Gliemann, J. (1989). Urokinase binds to a plasminogen activator inhibitor type-2-like molecule in placental microvillous membranes. BBA General Subjects, 986(1), 135-40.

Nielsen, A. J., Nielsen, M. C., Birn, H., Ivarsen, P., Møller, H. J. & Hviid, C. V. B. (2021). Urine soluble CD163 (sCD163) as biomarker in glomerulonephritis: stability, reference interval and diagnostic performance. Clinical Chemistry and Laboratory Medicine, 59(4), 701-709. https://doi.org/10.1515/cclm-2020-0466

Madsen, M. G., Nørregaard, R., Stødkilde-Jørgensen, L., Christensen, J. H., Jørgensen, T. M. & Frøkiær, J. (2012). Urine and kidney cytokine profiles in experimental unilateral acute and chronic hydronephrosis. Scandinavian Journal of Urology and Nephrology, 46(2), 91-96. https://doi.org/10.3109/00365599.2011.637958

Nørregaard, R., Jensen, B. L., Topcu, S. O., Wang, G., Schweer, H., Nielsen, S. & Frøkiaer, J. (2010). Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 298(4), R1017-25. https://doi.org/10.1152/ajpregu.00336.2009

Wu, Q. & Fenton, R. A. (2021). Urinary proteomics for kidney dysfunction: insights and trends. Expert Review of Proteomics, 18(6), 437-452. https://doi.org/10.1080/14789450.2021.1950535

Wilmer, M. J., Christensen, E. I., van den Heuvel, L. P., Monnens, L. A. & Levtchenko, E. A. (2008). Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. American Journal of Kidney Diseases, 51, 893-903.

Geurts, F., Chaker, L., van der Burgh, A. C., Cronin-Fenton, D., Fenton, R. A. & Hoorn, E. J. (2024). Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease. Journal of the American Heart Association, 13(4), Article e032835. https://doi.org/10.1161/JAHA.123.032835

Salih, M., Fenton, R. A., Zietse, R. & Hoorn, E. J. (2015). Urinary extracellular vesicles as markers to assess kidney sodium transport. Current Opinion in Nephrology & Hypertension. https://doi.org/10.1097/MNH.0000000000000192

Van Heugten, M. H., Hoorn, E. J. & Fenton, R. A. (2022). Urinary extracellular vesicles: does cargo reflect tissue? Current Opinion in Nephrology and Hypertension, 31(5), 464-470. https://doi.org/10.1097/MNH.0000000000000822

Nielsen, C. B., Birn, H., Brandt, F. & Kampmann, J. D. (2022). Urinary Dipstick Is Not Reliable as a Screening Tool for Albuminuria in the Emergency Department—A Prospective Cohort Study. Diagnostics, 12(2), Article 457. https://doi.org/10.3390/diagnostics12020457

Rodionova, E. A., Kuznetsova, A. A., Shakhmatova, E. I., Prutskova, N., Nielsen, S., Holtbäck, U., Natochin, Y. & Zelenina, M. (2006). Urinary Aquaporin-2 in Children with Acute Pyelonephritis. Pediatric Nephrology, 21, 361-367.

Foerster, R. H., Lamprecht, G., Rischmüller, K., Berlin, P., Rousing, A. Q., Sørensen, M. V., Leipziger, J. & Berg, P. (2024). Urinary acid-base excretion deciphers high acid load from colonic bicarbonate loss in intestinal failure patients with ileocolonic anastomosis: guidance for composition of parenteral support. Clinical Nutrition, 43(5), 1043-1050. https://doi.org/10.1016/j.clnu.2024.03.007

Wang, G., Li, C., Kim, SW., Ring, T., Wen, J., Djurhuus, J. C., Wang, W., Nielsen, S. & Frøkiær, J. (2008). Ureter obstruction alters expression of renal acid-base transport proteins in rat kidney. American Journal of Physiology: Renal Physiology, 295(2), 497-506.

Mutsaers, H. A. M., van den Heuvel, L. P., Ringens, L. H. J., Dankers, A. C. A., Russel, F. G. M., Wetzels, J. F. M., Hoenderop, J. G. & Masereeuw, R. (2011). Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. PLOS ONE, 6(4), Article e18438. https://doi.org/10.1371/journal.pone.0018438

Fenton, R. A. & Yang, B. (2014). Urea transporter knockout mice and their renal phenotypes. Sub-cellular Biochemistry, 73, 137-52. https://doi.org/10.1007/978-94-017-9343-8_9

Stewart, G. S., Fenton, R. A., Thévenod, F. & Smith, C. P. (2004). Urea movement across mouse colonic plasma membranes is mediated by UT-A urea transporters. Gastroenterology, 126(3), 765-73. https://doi.org/10.1053/j.gastro.2003.11.045

Locht, L. J., Smidt, K., Rungby, J., Stoltenberg, M. & Larsen, A. (2011). Uptake of silver from metallic silver surfaces induces cell death and a pro-inflammatory response in cultured J774 macrophages. Histology and Histopathology, 26(6).

Jessen, H., Røigaard, H. & Jacobsen, C. (1996). Uptake of neutral alpha- and beta-amino acids by human proximal tubular cells. BBA General Subjects, 1282(2), 225-32.

Seppälä, T. T., Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L. ... Møller, P. (2021). Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report. European Journal of Cancer, 148, 124-133. https://doi.org/10.1016/j.ejca.2021.02.022

Meier, M., Knudsen, A. R., Andersen, K. J., Ludvigsen, M., Eriksen, P. L., Honoré, B. & Mortensen, F. V. (2019). Upregulation of ureagenesis may be pivotal for survival of post-hepatectomy liver failure in rats. Poster session presented at 13th Congress of the European – African Hepato-Pancreato-Biliary Association, Amsterdam, Netherlands.

Coulson, E. J. & Nykjaer, A. (2013). Up-regulation of sortilin mediated by amyloid-β and p75(NTR): safety lies in the middle course. Journal of Neurochemistry, 127(2), 149-51. https://doi.org/10.1111/jnc.12389

Sørensen, K. M. J., Meldgaard, T., Melchjorsen, C. J., Fridriksdottir, A. J., Pedersen, H., Petersen, O. W. & Kristensen, P. (2017). Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections. BMC Cancer, 17(1), 19. Article 19. https://doi.org/10.1186/s12885-016-2987-5

Staehr, C., Rajanathan, R. & Matchkov, V. (2019). Upregulation of Endothelial Kir2. 1 Channel Disturbs Neurovascular Coupling in Familial Hemiplegic Migraine. Acta Physiologica (Print), 227(S721), 121-121.

Capasso, G., Rizzo, M., Garavaglia, M. L., Trepiccione, F., Zacchia, M., Mugione, A., Ferrari, P., Paulmichl, M., Lang, F., Loffing, J., Carrel, M., Damiano, S., Wagner, C. A., Bianchi, G. & Meyer, G. (2008). Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension. American Journal of Physiology: Renal Physiology, 295(2), F556-67. https://doi.org/10.1152/ajprenal.00340.2007

Voss, N. C. S., Kold-Petersen, H. H., Henningsen, M. B., Homilius, C. & Boedtkjer, E. (2019). Upregulated Na⁺/H⁺-exchange protects human colon cancer tissue against intracellular acidification. BioMed Research International, 2019, Article 3702783. https://doi.org/10.1155/2019/3702783

Gammelgaard, K. R., Vad-Nielsen, J., Clement, M. S., Weiss, S., Daugaard, T. F., Dagnæs-Hansen, F., Meldgaard, P., Sorensen, B. S. & Nielsen, A. L. (2019). Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC. Translational Oncology, 12(3), 432-440. https://doi.org/10.1016/j.tranon.2018.11.017

Frøbert, O., Funch-Jensen, P., Jacobsen, N. O., Kruse, A. & Bagger, J. P. (1995). Upper endoscopy in patients with angina and normal coronary angiograms. Endoscopy, 27(5), 365-70. https://doi.org/10.1055/s-2007-1005715

Nielsen, K., Hjortdal, J., Pihlmann, M. & Corydon, T. J. (2012). Update on the keratoconus genetics. Acta Ophthamologica (Online). https://doi.org/10.1111/j.1755-3768.2012.02400.x

Rasmussen, M. R., Nielsen, K. L., Christensen, M. B. L. R., Nielsen, C. B., Svendsen, P., Dimke, H., Christensen, E. I., Johannsen, M. & Moestrup, S. K. (2016). Untargeted Metabolomics Analysis of ABCC6-Deficient Mice Discloses an Altered Metabolic Liver Profile. Journal of Proteome Research, 15(12), 4591-4600. https://doi.org/10.1021/acs.jproteome.6b00669

Shepherd, G. M. G. & Yamawaki, N. (2021). Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle. Nature Reviews. Neuroscience, 22(7), 389-406.

Maddika, S., Panigrahi, S., Wiechec, E., Wesselborg, S., Fischer, U., Schulze-Osthoff, K. & Los, M. (2008). Unscheduled Akt-triggered activation of CDK2 as a key effector mechanism of apoptin's anticancer toxicity. Molecular and Cellular Biology.

Quintanova, C., Himmerkus, N., Svendsen, S. L., von Schwerdtner, O., Merkel, C., Pinckert, L., Mutig, K., Breiderhoff, T., Müller, D., Günzel, D. & Bleich, M. (2022). Unrecognized role of claudin-10b in basolateral membrane infoldings of the thick ascending limb. Annals of the New York Academy of Sciences, 1517(1), 266-278. https://doi.org/10.1111/nyas.14882

Traversa, D., Simonetti, G., Tolomeo, D., Visci, G., Macchia, G., Ghetti, M., Martinelli, G., Kristensen, L. S. & Storlazzi, C. T. (2022). Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease. British Journal of Cancer, 126(6), 835-850. https://doi.org/10.1038/s41416-021-01584-7

Ottosson, F., Russo, F., Abrahamsson, A., MacSween, N., Courraud, J., Skogstrand, K., Melander, O., Ericson, U., Orho-Melander, M., Cohen, A. S., Grove, J., Mortensen, P. B., Hougaard, D. M. & Ernst, M. (2024). Unraveling the metabolomic architecture of autism in a large Danish population-based cohort. BMC Medicine, 22(1), Article 302. https://doi.org/10.1186/s12916-024-03516-7

Takeuchi, T. (2024). Unlocking the memory vault: Dopamine, novelty, and memory consolidation in the hippocampus. In S. Sajikumar & T. Abel (Eds.), Synaptic Tagging and Capture: From Synapses to Behavior (2. ed., pp. 265-292). Springer International Publishing. https://doi.org/10.1007/978-3-031-54864-2_14

Kerr, A. M. & Capogna, M. (2007). Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus. The Journal of Physiology, 578(Pt 2), 451-70. https://doi.org/10.1113/jphysiol.2006.121608

Jensen, A., Ladegaard Grønkjær, L., Holmstrup, P., Vilstrup, H. & Kilian, M. (2018). Unique subgingival microbiota associated with periodontitis in cirrhosis patients. Scientific Reports, 8(1), Article 10718. https://doi.org/10.1038/s41598-018-28905-w

Sanggaard, K. W., Danielsen, C. C., Wogensen, L., Vinding, M. S., Rydtoft, L. M., Mortensen, M. B., Karring, H., Nielsen, N. C., Wang, T., Thøgersen, I. B. & Enghild, J. J. (2012). Unique structural features facilitate lizard tail autotomy. P L o S One, 7(12), e51803. https://doi.org/10.1371/journal.pone.0051803

Troldborg, A., Thiel, S., Mistegaard Jørgensen, C., Stengaard-Pedersen, K. & Loft, A. G. R. (2018). Unique Pattern of Lectin Pathway Complement Protein Levels in Axial Spondyloarthritis.

Hermans-Borgmeyer, I., Hampe, W., Schinke, B., Methner, A., Nykjaer, A., Süsens, U., Fenger, U., Herbarth, B. & Schaller, H. C. (1998). Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex. Mechanisms of Development, 70(1-2), 65-76.

Wang, G., Ring, T., Li, C., Kim, S. W., Wen, J., Djurhuus, J. C., Nielsen, S. & Frøkiær, J. (2009). Unilateral Ureteral Obstruction Alters Expression of Acid-Base Transporters in Rat Kidney. Journal of Urology, 182(6), 2964-73. https://doi.org/10.1016/j.juro.2009.08.013

Kierulf-Lassen, C., Nielsen, P. M., Qi, H., Damgaard, M., Laustsen, C., Pedersen, M., Krag, S., Birn, H., Nørregaard, R. & Jespersen, B. (2017). Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses. P L o S One, 12(12), e0190009. Article e0190009. https://doi.org/10.1371/journal.pone.0190009

Mogensen, T. H. (2022). Unexplored roles of type I interferon in antiviral immunity and regulation of inflammation revealed by studying patients with inborn errors of immunity. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 74(1), 140–143. https://doi.org/10.1093/cid/ciaa1798

Zeng, Q., Mousa, M., Nadukkandy, A. S., Franssens, L., Alnaqbi, H., Alshamsi, F. Y., Safar, H. A. & Carmeliet, P. (2023). Understanding tumour endothelial cell heterogeneity and function from single-cell omics. Nature Reviews Cancer, 23(8), 544-564. https://doi.org/10.1038/s41568-023-00591-5

Ribeiro, S., Ribeiro, C., Martins, V. M., Honoré, B., Neves-Petersen, M. T., Gomes, A. C. & Lanceros-Mendez, S. (2022). Understanding Myoblast Differentiation Pathways When Cultured on Electroactive Scaffolds through Proteomic Analysis. ACS applied materials & interfaces, 14(22), 26180-26193. https://doi.org/10.1021/acsami.2c03444

Dollerup, O. L., Treebak, J. T. & Jessen, N. (2019). Underpowered or negative? A crucial distinction. Diabetologia, 62(6), 1094-1095. https://doi.org/10.1007/s00125-019-4853-x

Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A., Otzen, D., Klenerman, D., Matthews, S., Linse, S., Andreasen, M. & Knowles, T. P. J. (2022). Uncovering the universality of self-replication in protein aggregation and its link to disease. Science Advances, 8(32), Article eabn6831. https://doi.org/10.1126/sciadv.abn6831

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Revised 14.09.2020