Peer-reviewed publications

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Dietz, L. L., Furman, N. T., Larsen, T. V., Daugaard, T. F., Thomsen, E. A., Keller, J. L., Aagaard, L., Sorensen, B. S. & Nielsen, A. L. (2022). An Extended PD-L2 Cytoplasmic Domain Results From Alternative Splicing in NSCLC Cells. Journal of Immunotherapy, 45(9), 379-388. https://doi.org/10.1097/CJI.0000000000000439

Subramanian, A., Zakeri, P., Mousa, M., Alnaqbi, H., Alshamsi, F. Y., Bettoni, L., Damiani, E., Alsafar, H., Saeys, Y. & Carmeliet, P. (2022). Angiogenesis goes computational – The future way forward to discover new angiogenic targets? Computational and Structural Biotechnology Journal, 20, 5235-5255. https://doi.org/10.1016/j.csbj.2022.09.019

Fabian-Jessing, B. K., Jakobsen, T. S., Jensen, E. G., Alsing, S., Hansen, S., Aagaard, L., Askou, A. L., Bek, T. & Corydon, T. J. (2022). Animal Models of Choroidal Neovascularization: A Systematic Review. Investigative Ophthalmology & Visual Science, 63(9), Article 11. https://doi.org/10.1167/iovs.63.9.11

Vilsen, B., Holm, R. & Nielsen, H. N. (2022). A novel super-efficient rescue mutation restoring the functional capability of Na,K-ATPase α3 in neurological disease. 58-59. Poster session presented at 16th International Conference on NA,K-ATPase and Related Transport ATPases, Banff, Canada.

Holm, R., Nielsen, H. N. & Vilsen, B. (2022). A novel super-efficient rescue mutation restoring the functional capability of Na,K-ATPase α3 in neurological disease.. Abstract from 16th International Conference on NA,K-ATPase and Related Transport ATPases, Banff, Canada.

Fahlquist-Hagert, C. (2022). Antibodies to cartilage oligomeric matrix protein are pathogenic in mice and may be clinically relevant in rheumatoid arthritis. Arthritis & Rheumatology, 74(6), 961-971. https://doi.org/10.1002/art.42072

Brent, M. B., Brüel, A. & Thomsen, J. S. (2022). Anti-sclerostin antibodies and abaloparatide have additive effects when used as a countermeasure against disuse osteopenia in female rats. Bone, 160, Article 116417. https://doi.org/10.1016/j.bone.2022.116417

Müller, R. U., Messchendorp, A. L., Birn, H., Capasso, G., Cornec-Le Gall, E., Devuyst, O., van Eerde, A., Guirchoun, P., Harris, T., Hoorn, E. J., Knoers, N. V. A. M., Korst, U., Mekahli, D., Le Meur, Y., Nijenhuis, T., Ong, A. C. M., Sayer, J. A., Schaefer, F., Servais, A. ... Gansevoort, R. T. (2022). An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Nephrology Dialysis Transplantation, 37(5), 825-839. https://doi.org/10.1093/ndt/gfab312

Pirhaghi, M., Frank, S. A., Alam, P., Nielsen, J., Sereikaite, V., Gupta, A., Strømgaard, K., Andreasen, M., Sharma, D., Saboury, A. A. & Otzen, D. E. (2022). A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers. Journal of Biological Chemistry, 298(12), Article 102688. https://doi.org/10.1016/j.jbc.2022.102688

Antaki, D., Guevara, J., Maihofer, A. X., Klein, M., Gujral, M., Grove, J., Carey, C. E., Hong, O., Arranz, M. J., Hervas, A., Corsello, C., Vaux, K. K., Muotri, A. R., Iakoucheva, L. M., Courchesne, E., Pierce, K., Gleeson, J. G., Robinson, E. B., Nievergelt, C. M. & Sebat, J. (2022). A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nature Genetics, 54(9), 1284-1292. https://doi.org/10.1038/s41588-022-01064-5

Thomsen, M. K. (2022). Application of CRISPR for In Vivo Mouse Cancer Studies. Cancers, 14(20), Article 5014. https://doi.org/10.3390/cancers14205014

Jensen, J. B., Dollerup, O. L., Møller, A. B., Billeskov, T. B., Dalbram, E., Chubanava, S., Damgaard, M. V., Dellinger, R. W., Trošt, K., Moritz, T., Ringgaard, S., Møller, N., Treebak, J. T., Farup, J. & Jessen, N. (2022). A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals. JCI Insight, 7(19), Article e158314. https://doi.org/10.1172/jci.insight.158314

Herold, J. & Kalucka, J. (2022). A Rapid Adaptable Method for Isolation of Endothelial Cells from Human Adipose Tissue. In A. V. Benest (Ed.), Angiogenesis (pp. 235-250). Humana Press. https://doi.org/10.1007/978-1-0716-2059-5_18

Brent, M. B. (2022). A review of the skeletal effects of exposure to high altitude and potential mechanisms for hypobaric hypoxia-induced bone loss. Bone, 154, Article 116258. https://doi.org/10.1016/j.bone.2021.116258

de Rooij, L. P. M. H., Becker, L. M. & Carmeliet, P. (2022). A Role for the Vascular Endothelium in Post-Acute COVID-19? Circulation, 145(20), 1503-1505. https://doi.org/10.1161/CIRCULATIONAHA.122.059231

Jägers, J., Kirsch, M., Cantore, M., Karaman, O. & Ferenz, K. B. (2022). Artificial oxygen carriers in organ preservation: Dose dependency in a rat model of ex-vivo normothermic kidney perfusion. Artificial organs, 46(9), 1783-1793. https://doi.org/10.1111/aor.14264

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S.-H., Ferreira, T., Highland, H. H. ... Understanding Society Scientific Group (2022). A saturated map of common genetic variants associated with human height. Nature, 610(7933), 704–712. https://doi.org/10.1038/s41586-022-05275-y

Ren, T., Zhang, J., Yu, Y., Pedersen, L. H., Wang, H., Li, F., Henriksen, T. B. & Li, J. (2022). Association of labour epidural analgesia with neurodevelopmental disorders in offspring: a Danish population-based cohort study. British Journal of Anaesthesia, 128(3), 513-521. https://doi.org/10.1016/j.bja.2021.10.042

Yde, J., Wu, Q., Borg, J. F., Fenton, R. A. & Moeller, H. B. (2022). A systems-level analysis of bile acids effects on rat colon epithelial cells. American Journal of Physiology - Gastrointestinal and Liver Physiology, 322(1), G34-G48. https://doi.org/10.1152/ajpgi.00178.2021

í Kongsstovu, S., Mikalsen, S. O., Homrum, E., Jacobsen, J. A., Als, T. D., Gislason, H., Flicek, P., Nielsen, E. E. & Dahl, H. A. (2022). Atlantic herring (Clupea harengus) population structure in the Northeast Atlantic Ocean. Fisheries Research, 249, Article 106231. https://doi.org/10.1016/j.fishres.2022.106231

Ernst, C., Aalkjær, C. & Bek, T. (2022). ATP induced calcium signaling activity in perivascular cells differ at different vascular branch levels in the porcine retina. Microvascular Research, 139, Article 104256. https://doi.org/10.1016/j.mvr.2021.104256

Gao, Z., Ravendran, S., Mikkelsen, N. S., Haldrup, J., Cai, H., Ding, X., Paludan, S. R., Thomsen, M. K., Mikkelsen, J. G. & Bak, R. O. (2022). A truncated reverse transcriptase enhances prime editing by split AAV vectors. Molecular Therapy, 30(9), 2942-2951. https://doi.org/10.1016/j.ymthe.2022.07.001

Demir, F. & Huesgen, P. F. (2022). A User Guide to Validation, Annotation, and Evaluation of N-Terminome Datasets with MANTI. In Methods in Molecular Biology (pp. 271-283). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2079-3_22

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (Nature Communications, (2022), 13, 1, (3620), 10.1038/s41467-022-31388-z). Nature Communications, 13(1), Article 6748. https://doi.org/10.1038/s41467-022-34498-w

DBDS Genetic Consortium & GO Consortium (2022). Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology (Nature Communications, (2022), 13, 1, (634), 10.1038/s41467-022-28167-1). Nature Communications, 13(1), Article 2419. https://doi.org/10.1038/s41467-022-30129-6

Loucif, H., Dagenais-Lussier, X., Avizonis, D., Choinière, L., Beji, C., Cassin, L., Routy, J.-P., Fritz, J. H., Olagnier, D. & van Grevenynghe, J. (2022). Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells. Autophagy, 18(6), 1256-1273. https://doi.org/10.1080/15548627.2021.1972403

Mavroeidi, P., Arvanitaki, F., Vetsi, M., Becker, S., Vlachakis, D., Jensen, P. H., Stefanis, L. & Xilouri, M. (2022). Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models. Autophagy, 18(9), 2104-2133. https://doi.org/10.1080/15548627.2021.2016256

Deen, P. M. T., Boone, M., Schweer, H., Olesen, E. T. B., Carmone, C., Wetzels, J. F. M., Fenton, R. A. & Kortenoeven, M. L. A. (2022). A Vasopressin-Induced Change in Prostaglandin Receptor Subtype Expression Explains the Differential Effect of PGE₂on AQP2 Expression. Frontiers in Physiology, 12, Article 787598. https://doi.org/10.3389/fphys.2021.787598

Walter, A. & Bilde, T. (2022). Avoiding the tragedy of the commons: Improved group-feeding performance in kin groups maintains foraging cooperation in subsocial Stegodyphus africanus spiders (Araneae, Eresidae). Journal of Evolutionary Biology, 35(3), 391-399. https://doi.org/10.1111/jeb.13976

AlZaim, I. & Kalucka, J. (2022). Batokine neuregulin 4 promotes atherosclerotic resolution. Nature Metabolism, 4(11), 1440-1441. https://doi.org/10.1038/s42255-022-00669-8

Nielsen, A. F., Bindereif, A., Bozzoni, I., Hanan, M., Hansen, T. B., Irimia, M., Kadener, S., Kristensen, L. S., Legnini, I., Morlando, M., Olesen, M. T. J., Pasterkamp, R. J., Preibisch, S., Rajewsky, N., Sünkel, C. & Kjems, J. (2022). Best practice standards for circular RNA research. Nature Methods, 19(10), 1208-1220. https://doi.org/10.1038/s41592-022-01487-2

Silva, M. G. D., Barbosa, S. L. F., Silva, D. S., Bezerra, I. B. M., Alves Bezerra, É., Coelho, A. G., Pinheiro da Silva Morais, I. C., Rezende-Júnior, L. M., Carmo, I. S. D., Lima-Neto, J. D. S., Comerma-Steffensen, S. G., Citó, A. M. D. G. L. & Arcanjo, D. D. R. (2022). Bioactive Natural Products against Systemic Arterial Hypertension: A Past 20-Year Systematic and Prospective Review. Evidence-Based Complementary and Alternative Medicine, 2022, Article 8499625. https://doi.org/10.1155/2022/8499625

Afshar, M., Møllebjerg, A., Minero, G. A., Hollensteiner, J., Poehlein, A., Himmelbach, A., Lange, J., Meyer, R. L. & Brüggemann, H. (2022). Biofilm formation and inflammatory potential of Staphylococcus saccharolyticus: A possible cause of orthopedic implant-associated infections. Frontiers in Microbiology, 13, Article 1070201. https://doi.org/10.3389/fmicb.2022.1070201

Walter, F. R., Harazin, A., Tóth, A. E., Veszelka, S., Santa-Maria, A. R., Barna, L., Kincses, A., Biczó, G., Balla, Z., Kui, B., Maléth, J., Cervenak, L., Tubak, V., Kittel, Á., Rakonczay, Z. & Deli, M. A. (2022). Blood–brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells. Fluids and Barriers of the CNS, 19(1), Article 16. https://doi.org/10.1186/s12987-022-00308-0

Takeuchi, T., Tamura, M., Tse, D., Kajii, Y., Fernández, G. & Morris, R. G. M. (2022). Brain region networks for the assimilation of new associative memory into a schema. Molecular Brain, 15, Article 24. https://doi.org/10.1186/s13041-022-00908-9

Jensen, R. K., Christensen, A. F., Hartlev, L. B., Thomsen, J. S., Boel, L. W. T., Laursen, M. B., Revald, P., Varnum, C., Keller, K. K. & Hauge, E. M. (2022). Calcified cartilage differs in patients with end-stage primary osteoarthritis and secondary osteoarthritis due to rheumatoid arthritis of the hip joint. Scandinavian Journal of Rheumatology, 51(6), 441-451. https://doi.org/10.1080/03009742.2021.1952754

Cortés-Sánchez, J. L., Callant, J., Krüger, M., Sahana, J., Kraus, A., Baselet, B., Infanger, M., Baatout, S. & Grimm, D. (2022). Cancer studies under space conditions: Finding answers abroad. Biomedicines, 10(1), Article 25. https://doi.org/10.3390/biomedicines10010025

Mårup, F. H., Peters, C. D., Christensen, J. H. & Birn, H. (2022). Can patiromer allow for intensified renin-angiotensin-aldosterone system blockade with losartan and spironolactone leading to decreased albuminuria in patients with chronic kidney disease, albuminuria and hyperkalaemia? An open-label randomised controlled trial: MorphCKD. BMJ Open, 12(2), Article e057503. https://doi.org/10.1136/bmjopen-2021-057503

Jankowski, V., Saritas, T., Kjolby, M., Hermann, J., Speer, T., Himmelsbach, A., Mahr, K., Heuschkel, M. A., Schunk, S. J., Thirup, S., Winther, S., Bottcher, M., Nyegard, M., Nykjaer, A., Kramann, R., Kaesler, N., Jankowski, J., Floege, J., Marx, N. & Goettsch, C. (2022). Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney International, 101(3), 574-584. https://doi.org/10.1016/j.kint.2021.10.018

Rise, N., Touborg, T., Lundsted, D. H., Dalager-Pedersen, M. & Mogensen, T. H. (2022). Case report: Evolution of pulmonary manifestations and virological markers in critical COVID-19 infection in Bruton’s agammaglobulinemia. Frontiers in Immunology, 13, Article 1057065. https://doi.org/10.3389/fimmu.2022.1057065

Rossen, L. S., Schack, V., Thuesen, K. K. H., Bundgaard, B. & Höllsberg, P. B. (2022). CD46 isoforms influence the mode of entry by human herpesvirus 6A/B in T cells. Journal of Virology, 96(5), Article e01557-21. https://doi.org/10.1128/jvi.01557-21

Fernández-García, J., Franco, F., Parik, S., Altea-Manzano, P., Pane, A. A., Broekaert, D., van Elsen, J., Vermeire, I., Schalley, T., Planque, M., van Brussel, T., Schepers, R., Modave, E., Karakach, T. K., Carmeliet, P., Lambrechts, D., Ho, P. C. & Fendt, S. M. (2022). CD8⁺ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation. Cell Reports, 41(7), Article 111639. https://doi.org/10.1016/j.celrep.2022.111639

Vorperian, S. K., Moufarrej, M. N., Tabula Sapiens Consortium & Quake, S. R. (2022). Cell types of origin of the cell-free transcriptome. Nature Biotechnology, 40(6), 855-861. https://doi.org/10.1038/s41587-021-01188-9

Berg, P., Sorensen, M. V., Rousing, A. Q., Olesen, H. V., Jensen-Fangel, S., Jeppesen, M. & Leipziger, J. (2022). Challenged Urine Bicarbonate Excretion as a Measure of Cystic Fibrosis Transmembrane Conductance Regulator Function in Cystic Fibrosis. Annals of Internal Medicine, 175(11), 1543-1551. https://doi.org/10.7326/M22-1741

Konstantin Nissen, S., Farmen, K., Carstensen, M., Schulte, C., Goldeck, D., Brockmann, K. & Romero‐Ramos, M. (2022). Changes in CD163+, CD11b+, and CCR2+ peripheral monocytes relate to Parkinson's disease and cognition. Brain, Behavior, and Immunity, 101, 182-193. https://doi.org/10.1016/j.bbi.2022.01.005

Knudsen, J. S., Knudsen, S. S., Hulman, A., Witte, D. R., Gregg, E. W., Lauritzen, T., Pedersen, L., Sørensen, H. T. & Thomsen, R. W. (2022). Changes in type 2 diabetes incidence and mortality associated with introduction of HbA1c as diagnostic option: A Danish 24-year population-based study. The Lancet Regional Health - Europe, 14, Article 100291. https://doi.org/10.1016/j.lanepe.2021.100291

Frøbert, A. M., Brohus, M., Toews, J. N. C., Round, P., Fröbert, O., Hammond, G. L. & Overgaard, M. T. (2022). Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin. FEBS Open Bio, 12(2), 362-378. https://doi.org/10.1002/2211-5463.13341

Torm, M. E. W., Sander, B., Hornum, M., Krohn, P., Birn, H. & Larsen, M. (2022). Characterization of Hyperreflective Dots by Structural and Angiographic Optical Coherence Tomography in Patients with Diabetic Retinopathy and Healthy Subjects. Journal of Clinical Medicine, 11(22), Article 6646. https://doi.org/10.3390/jcm11226646

Girdhar, K., Hoffman, G. E., Bendl, J., Rahman, S., Dong, P., Liao, W., Hauberg, M. E., Sloofman, L., Brown, L., Devillers, O., Kassim, B. S., Wiseman, J. R., Park, R., Zharovsky, E., Jacobov, R., Flatow, E., Kozlenkov, A., Gilgenast, T., Johnson, J. S. ... PsychENCODE Consortium (2022). Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains. Nature Neuroscience, 25(4), 474-483. https://doi.org/10.1038/s41593-022-01032-6

Kravtsova, V. V., Fedorova, A. A., Tishkova, M. V., Livanova, A. A., Vetrovoy, O. V., Markov, A. G., Matchkov, V. V. & Krivoi, I. I. (2022). Chronic Ouabain Prevents Radiation-Induced Reduction in the α2 Na,K-ATPase Function in the Rat Diaphragm Muscle. International Journal of Molecular Sciences , 23(18), Article 10921. https://doi.org/10.3390/ijms231810921

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Revised 14.09.2020