Peer-reviewed publications

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Hansen, T. F., Aalund Olsen, D., Sørensen, F. B. & Jakobsen, A. (2016). Circulating epidermal growth factor-like domain 7 has prognostic impact in patients with metastatic cancer.

Brøsen, K., Andersen, S. E., Borregaard, J., Christensen, H. R., Christensen, P. M., Dalhoff, K. P., Damkier, P., Hallas, J., Heisterberg, J., Jessen, N., Jürgens, G., Kampmann, J. P. K., Laursen, B. E., Laursen, T., Nielsen, L. P., Poulsen, B. K., Poulsen, H. E., Andersen, L. V., Senderovitz, T. & Sonne, J. (2016). Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality. Basic & Clinical Pharmacology & Toxicology, 119(6), 523-532. https://doi.org/10.1111/bcpt.12681

Petruskevicius, I., Ludvigsen, M., Hjortebjerg, R., Sørensen, B. S., Kamper, P., Vase, M. Ø., Oestgaard, L. G., Nielsen, B., Honoré, B., Bjerre, M., Rabinovich, G. A. & d'Amore, F. A. (2016). Clinical relevance of galectin-1 in hematologic malignancies treated with non-myeloablative hemopoietic stem cell transplantation. Bone Marrow Transplantation, 51(10), 1387-1390. https://doi.org/10.1038/bmt.2016.127

Holm, T. H., Isaksen, T. J., Pedersen, S. G., Heuck, A., Bøttger, P., Füchtbauer, E.-M., Nedergaard, S. T., Nyengaard, J. R., Andreasen, M., Nissen, P. & Lykke-Hartmann, K. (2016). Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform. Scientific Reports, 6(31972), Article 31972. https://doi.org/10.1038/srep31972

Leth, S., Schleimann, M. H., Nissen, S. K., Højen, J. F., Olesen, R., Graversen, M. E., Jorgensen, S., Kjær, A. S., Denton, P. W., Mørk, A., Sommerfelt, M. A., Krogsgaard, K., Østergaard, L., Rasmussen, T. A., Tolstrup, M. & Søgaard, O. S. (2016). Combined effect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial. The Lancet HIV, 3(10), e463–e472. https://doi.org/10.1016/S2352-3018(16)30055-8

Lønborg, J., Kelbæk, H., Holmvang, L., Helqvist, S., Vejlstrup, N., Jørgensen, E., Saunamäki, K., Dridi, N. P., Kløvgaard, L., Kaltoft, A., Bøtker, H.-E., Lassen, J. F., Clemmensen, P., Terkelsen, C. J. & Engstrøm, T. (2016). Comparison of Outcome of Patients With ST-Segment Elevation Myocardial Infarction and Complete Versus Incomplete ST-Resolution Before Primary Percutaneous Coronary Intervention. The American Journal of Cardiology, 117(11), 1735-40. https://doi.org/10.1016/j.amjcard.2016.03.009

Gotfred-Rasmussen, H., Lund, M., Enemark, H. L., Erlandsen, M. & Petersen, E. (2016). Comparison of sensitivity and specificity of 4 methods for detection of Giardia duodenalis in feces: immunofluorescence and PCR are superior to microscopy of concentrated iodine-stained samples. Diagnostic Microbiology and Infectious Disease, 84(3), 187-90. https://doi.org/10.1016/j.diagmicrobio.2015.11.005

Troldborg, A., Thiel, S., Jensen, L., Stengaard-Pedersen, K. & Jensenius, J. C. (2016). Complement activation evaluated by measurement of C3dg - A new assay and results from measurements in patients with SLE. Immunobiology Volume 221, Issue 10, Pages 1035-1226 2016.

Banda, N. K., Acharya, S., Scheinman, R. I., Mehta, G., Takahashi, M., Thiel, S., Sekine, H., Fujita, T. & Holers, V. M. (2016). Complement mannan-binding lectin associated serine proteases 1 and 3 generated by allo-liver transplantation cleave in vivo pro-Factor D generated by the adipose tissue into active Factor D. Journal of Immunology, 196(1 Supplement).

Yonehara, K., Fiscella, M., Drinnenberg, A., Esposti, F., Trenholm, S., Krol, J., Franke, F., Scherf, B. G., Kusnyerik, A., Müller, J., Szabo, A., Jüttner, J., Cordoba, F., Reddy, A. P., Németh, J., Nagy, Z. Z., Munier, F., Hierlemann, A. & Roska, B. (2016). Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity. Neuron, 89(1), 177-93. https://doi.org/10.1016/j.neuron.2015.11.032

Likus, W., Siemianowicz, K., Bienk, K., Pakula, M., Pathak, H., Dutta, C., Wang, Q., Shojaei, S., Assaraf, Y. G., Ghavami, S., Cieslar-Pobuda, A. & Los, M. J. (2016). Could drugs inhibiting the mevalonate pathway also target cancer stem cells? Drug Resistance Updates, 25, 13-25. https://doi.org/10.1016/j.drup.2016.02.001

Sehgal, P., Olesen, C. & Møller, J. V. (2016). Coupling ratio for ca²⁺ transport by calcium oxalate precipitation. Methods in Molecular Biology, 1377, 157-160. https://doi.org/10.1007/978-1-4939-3179-8_15

Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016). Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. Genetics (Print), 203(4), 1901-1913. https://doi.org/10.1534/genetics.116.189498

Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016). Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 5th International Conference on Quantitative Genetics , Madison, United States.

Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016). Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 2nd Annual Danish Bioinformatics Conference, Odense, Denmark.

Lin, L., Vad-Nielsen, J. & Luo, Y. (2016). CRISPR-mediated multiplexed genetic manipulation. OncoTargets and Therapy, 7(49), 80103-80104. https://doi.org/10.18632/oncotarget.13371

Clausen, J. D., Bublitz, M., Arnou, B. J.-P., Olesen, C., Andersen, J. P., Møller, J. V. & Nissen, P. (2016). Crystal Structure of the Vanadate-Inhibited Ca²⁺-ATPase. Structure, 24(4), 617-623. https://doi.org/10.1016/j.str.2016.02.018

Larsen, J. V., Kristensen, A. M., Pallesen, L. T., Bauer, J., Vægter, C. B., Nielsen, M. S., Madsen, P. & Petersen, C. M. (2016). Cytokine-like factor-1 (CLF-1): An essential facilitator of cardiotrophin-like cytokine: CNTFRα (CLC:CNTFRα) signalling and sorLA mediated turnover. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.00917-15

Nissen, L., Winther, S., Isaksen, C., Ejlersen, J. A., Brix, L., Urbonaviciene, G., Frost, L., Helleskov Madsen, L., Lyhne Knudsen, L., Schmidt, S. E., Holm, N. R., Maeng, M., Nyegaard, M., Bøtker, H. E. & Bøttcher, M. (2016). Danish study of Non-Invasive testintg in Coronary artery disease (Dan-NICAD): Study protocol for a randomised controlled trial. Trials, 17(1), Article 262. https://doi.org/10.1186/s13063-016-1388-z

Gunnarsson, A. P., Christensen, R., Li, J. & Jensen, U. B. (2016). Dataset on gene expression profiling of multiple murine hair follicle populations. Data in Brief, 9, 328-34. https://doi.org/10.1016/j.dib.2016.08.063

Sædder, E. A., Lisby, M., Nielsen, L. P., Rungby, J., Andersen, L. V., Bonnerup, D. K. & Brock, B. (2016). Detection of Patients at High Risk of Medication Errors: Development and Validation of an Algorithm. Basic & Clinical Pharmacology & Toxicology, 118(2), 143-149. https://doi.org/10.1111/bcpt.12473

Molgaard, S., Ulrichsen, M., Olsen, D. & Glerup, S. (2016). Detection of phosphorylated Akt and MAPK in cell culture assays. MethodsX, 3, 386-398. https://doi.org/10.1016/j.mex.2016.04.009

Clausen, J. D., McIntosh, D. B., Woolley, D. G. & Andersen, J. P. (2016). Determination of the ATP Affinity of the Sarcoplasmic Reticulum Ca(2+)-ATPase by Competitive Inhibition of [γ-(32)P]TNP-8N3-ATP Photolabeling. Methods in molecular biology (Clifton, N.J.), 1377, 233-59. https://doi.org/10.1007/978-1-4939-3179-8_22

Huebner, A. R., Cheng, L., Somparn, P., Knepper, M. A., Fenton, R. A. & Pisitkun, T. (2016). Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation. Molecular and Cellular Proteomics, 15(May), 1556-1571. https://doi.org/10.1074/mcp.M115.054965

Yiu, G., Rasmussen, T. K., Ajami, B., Haddon, D. J., Chu, A. D., Tangsombatvisit, S., Haynes, W. A., Diep, V., Steinman, L., Faix, J. & Utz, P. J. (2016). Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1. Arthritis & Rheumatology, 68(5), 1233–1244. https://doi.org/10.1002/art.39535

Storgaard, H., Bagger, J. I., Knop, F. K., Vilsbøll, T. & Rungby, J. (2016). Diabetic Ketoacidosis in a Patient with Type 2 Diabetes After Initiation of Sodium-Glucose Cotransporter 2 Inhibitor Treatment. Basic & Clinical Pharmacology & Toxicology, 118(2), 168-70. https://doi.org/10.1111/bcpt.12457

Lee, S., Axelsen, T. V., Andersen, A. P., Vahl, P., Pedersen, S. H. F. & Boedtkjer, E. (2016). Disrupting Na⁺,HCO₃^–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development. Oncogene, 35(16), 2112-2122.

Nielsen, R. B., Egefjord, L., Eskildsen, S. F., Møller, A., Brændgaard, H., Jensen, M. G., Brock, B., Rungby, J. & Østergaard, L. (2016). Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. Abstract from 10th FENS FORUM of Neuroscience 2016, København, Denmark.

Kravtsova, V., Petrov, A. M., Matchkov, V., Bouzinova, E., Vasiliev, A. N., Benziane, B., Zefirov, A. L., Chibalin, A. V., Heiny, J. A. & Krivoi, II. (2016). Distinct alpha2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse. Journal of General Physiology, 147(2), 175-188. https://doi.org/10.1085/jgp.201511494

Hertle, E., Arts, I. C. W., Van Der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Hoffmann-Petersen, I. T., Thiel, S., Stehouwer, C. D. A. & Van Greevenbroek, M. M. J. (2016). Distinct longitudinal associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 with endothelial dysfunction and intima-media thickness. Arteriosclerosis, Thrombosis, and Vascular Biology, 36(6), 1278-1285. https://doi.org/10.1161/ATVBAHA.115.306552

Mikkelsen, C. R., Jornil, J., Vukelic Andersen, L., Banner, J. & Hasselstrøm, J. B. (2016). Distribution of QT-prolonging drugs and metabolites between cardiac tissue and femoral blood in a psychiatric population. Abstract from SOFT 2016: Society of Forensic Toxicologists, Dallas, United States.

Nielsen, C. H., Larsen, A. & Nielsen, A. L. (2016). DNA methylation alterations in response to prenatal exposure of maternal cigarette smoking: A persistent epigenetic impact on health from maternal lifestyle? Archives of Toxicology, 90(2), 231-245. https://doi.org/10.1007/s00204-014-1426-0

Nissen, J. B., Søholm Hansen, C., Starnawska, A., Mattheisen, M., Børglum, A., Buttenschøn, H. N. & Hollegård, M. (2016). DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Frontiers in Psychiatry, 7(35), Article 35. https://doi.org/10.3389/fpsyt.2016.00035

Lyngsø, K. S., Assersen, K., Dalgaard, E. G., Skott, O., Jensen, B. L. & Hansen, P. B. L. (2016). Does Aldosterone Play a Significant Role for Regulation of Vascular Tone? Journal of Cardiovascular Pharmacology, 68(1), 1-10. https://doi.org/10.1097/FJC.0000000000000345

Hjorth, M. H., Egund, N., Mechlenburg, I., Gelineck, J., Jakobsen, S. S., Soballe, K. & Stilling, M. (2016). Does a titanium sleeve reduce the frequency of pseudotumors in metal-on-metal total hip arthroplasty at 5–7 years follow-up? Revue de Chirurgie Orthopedique et Traumatologique, 102(8), 739. https://doi.org/10.1016/j.rcot.2016.09.030

Staehr, C., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Aalkjær, C. & Matchkov, V. (2016). Dysfunctional neurovascular coupling in Familial hemiplegic migraine type 2. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 23.

Topol, A., Zhu, S., Hartley, B. J., English, J., Hauberg, M. E., Tran, N., Rittenhouse, C. A., Simone, A., Ruderfer, D. M., Johnson, J., Readhead, B., Hadas, Y., Gochman, P. A., Wang, Y.-C., Shah, H., Cagney, G., Rapoport, J., Gage, F. H., Dudley, J. T. ... Brennand, K. J. (2016). Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Reports, 15(5), 1024-36. https://doi.org/10.1016/j.celrep.2016.03.090

Jørgensen, S. E., Bøttger, P., Kofod-Olsen, E., Holm, M., Mørk, N., Ørntoft, T. F., Sørensen, U., Bernth-Jensen, J. M., Herlin, T., Veirum, J., Larsen, C. S., Østergaard, L. J., Hartmann, R., Christiansen, M. & Mogensen, T. (2016). Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO. Journal of Allergy and Clinical Immunology, 138(6), 1706-1709.e4. https://doi.org/10.1016/j.jaci.2016.05.030

Lebeck, J. (2016). Editorial: Sexual Dimorphism in Glucose and Lipid Metabolism. Frontiers in Endocrinology, 7(DEC), Article 166.

Laursen, R., Wehland, M., Kopp, S., Pietsch, J., Infanger, M., Grosse, J. & Grimm, D. (2016). Effects and Role of Multikinase Inhibitors in Thyroid Cancer. Current Pharmaceutical Design, 22(39), 5915-5926.

Bie, A. S., Fernandez-Guerra, P., Birkler, R. I. D., Nisemblat, S., Pelnena, D., Lu, X., Deignan, J. L., Lee, H., Dorrani, N., Corydon, T. J., Palmfeldt, J., Bivina, L., Azem, A., Herman, K. & Bross, P. (2016). Effects of a Mutation in the HSPE1 Gene Encoding the Mitochondrial Co-chaperonin HSP10 and Its Potential Association with a Neurological and Developmental Disorder. Frontiers in Molecular Biosciences, 3(OCT), 65. Article 65. https://doi.org/10.3389/fmolb.2016.00065

Andersen, M. N., Al-Karradi, S. N. H., Kragstrup, T. W. & Hokland, M. (2016). Elimination of erroneous results in flow cytometry caused by antibody binding to Fc receptors on human monocytes and macrophages. Cytometry. Part A, 89(11), 1001–1009. https://doi.org/10.1002/cyto.a.22995

Nexø, B. A., Bisgaard Jensen, S., Hansen, B. & Laska, M. J. (2016). Endogenous retroviruses are associated with autoimmune diseases. Ugeskrift for Læger, 178(24).

Shadnezhad, A., Naegeli, A., Sjögren, J., Adamczyk, B., Leo, F., Allhorn, M., G Karlsson, N., Jensen, A. & Collin, M. (2016). EndoSd: an IgG glycan hydrolyzing enzyme in Streptococcus dysgalactiae subspecies dysgalactiae. Future Microbiology, 11(6), 721-736. https://doi.org/10.2217/fmb.16.14

Dyla, M., Andersen, J., Kjaergaard, M., Birkedal, V., Terry, D. S., Altman, R. B., Blanchard, S., Nissen, P. & Knudsen, C. R. (2016). Engineering a prototypic P-type ATPase Listeria Monocytogenes Ca(2+)-ATPase 1 for single-molecule FRET studies. Bioconjugate Chemistry, 27(9), 2176-2187. https://doi.org/10.1021/acs.bioconjchem.6b00387

Zhou, Y., Liu, Y., Hussmann, D., Brøgger, P., Al-Saaidi, R. A., Tan, S., Lin, L., Petersen, T. S., Zhou, G. Q., Bross, P., Aagaard, L., Klein, T., Rønn, S. G., Pedersen, H. D., Bolund, L., Nielsen, A. L., Sørensen, C. B. & Luo, Y. (2016). Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system. Cellular and Molecular Life Sciences, 73(13), 2543-63. https://doi.org/10.1007/s00018-015-2128-3

Stenvang, M., Christiansen, G. & Otzen, D. E. (2016). Epigallocatechin gallate remodels fibrils of Lattice Corneal Dystrophy protein, facilitating proteolytic degradation and preventing formation of membrane-permeabilizing species. Biochemistry, 55(16), 2344-2357. https://doi.org/10.1021/acs.biochem.6b00063

Stenvang, M., Dueholm, M. S., Vad, B. S., Seviour, T. W., Zeng, G., Geifman-Shochat, S., Søndergaard, M. T., Christiansen, G., Meyer, R. L., Kjelleberg, S., Otzen, D. E. & Nielsen, P. H. (2016). Epigallocatechin Gallate Remodels overexpressed Functional Amyloids in Pseudomonas aeruginosa and Increases Biofilm Susceptibility to Antibiotic Treatment. Journal of Biological Chemistry, 291(51), 26540-26553. https://doi.org/10.1074/jbc.M116.739953

Viuff, A.-C. F., Pedersen, L. H., Kyng, K. J., Staunstrup, N. H., Børglum, A. & Henriksen, T. B. (2016). Epigenetic changes in newborns exposed to antidepressant medication during pregnancy - a planned genome wide study. Poster session presented at 2016 Epidemiology Conference of the Americas, Miami, United States.

David-Bosne, S., Clausen, M. V., Poulsen, H., Møller, J. V., Nissen, P. & Le Maire, M. (2016). Erratum: Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes (Nature Structural and Molecular Biology (2016) 23 (1-2)). Nature Structural and Molecular Biology, 23(4). https://doi.org/10.1038/nsmb0416-358a

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Revised 14.09.2020