Peer-reviewed publications

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Klinger, S. C., Glerup, S., Raarup, M. K., Mari, M. C., Nyegaard, M., Koster, G., Prabakaran, T., Nilsson, B. S., Kjaergaard, M. M., Bakke, O., Nykjær, A., Olivecrona, G., Petersen, C. M. & Nielsen, M. S. (2011). SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. Journal of Cell Science, 124(Pt 7), 1095-105. https://doi.org/10.1242/jcs.072538

Vaegter, C. B., Jansen, P., Fjorback, A. W., Glerup, S., Skeldal, S., Kjølby, M. F., Richner, M., Erdmann, B., Nyengaard, J. R., Tessarollo, L., Lewin, G. R., Willnow, T. E., Chao, M. V. & Nykjaer, A. (2011). Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nature Neuroscience, 14(1), 54-61. https://doi.org/10.1038/nn.2689

Willnow, T., Kjølby, M. F. & Nykjær, A. (2011). Sortilins: new players in lipoprotein metabolism. Current Opinion in Lipidology, 22(2), 79-85. https://doi.org/10.1097/MOL.0b013e3283416f2b

Yonehara, K., Balint, K., Noda, M., Nagel, G., Bamberg, E. & Roska, B. (2011). Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature, 469(7330), 407-10. https://doi.org/10.1038/nature09711

Guzzi, R., Babavali, M., Bartucci, R., Sportelli, L., Esmann, M. & Marsh, D. (2011). Spin-echo EPR of Na,K-ATPase unfolding by urea. BBA General Subjects, 1808, 1618-1628. https://doi.org/10.1016/j.bbamem.2010.11.008

Blumberga, G., Groes, L. & Dahl, R. (2011). SQ-standardized house dust mite immunotherapy as an immunomodulatory treatment in patients with asthma. Allergy: European Journal of Allergy and Clinical Immunology, 66(2), 178-85. https://doi.org/10.1111/j.1398-9995.2010.02451.x

Kapri-Pardes, E., Katz, A., Haviv, H., Mahmmoud, Y. A., Ilan, M., Khalfin-Penigel, I., Carmeli, S., Yarden, O. & Karlish, S. J. (2011). Stabilization of the α2 isoform of Na,K-ATPase by mutations in a phospholipid binding pocket. Journal of Biological Chemistry, 286(50), 42888-42899. https://doi.org/10.1074/jbc.M111.293852

Holm, M. M., Nieto-Gonzales, J. L., Vardya, I., Christensen, T., Wiborg, O. & Jensen, K. (2011). Stress-susceptibility and resilience can be distinguished by hippocampal electrophysiological analysis in a chronic mild stress rat model of depression. Abstract from The Brain Prize Meeting, Aarhus, Denmark.

Brüel, A., Olsen, J., Birkedal, H., Risager, M. B., Andreassen, T. T., Raffalt, A. C., Andersen, J. E. T. & Thomsen, J. S. (2011). Strontium Is Incorporated Into the Fracture Callus But Does Not Influence the Mechanical Strength of Healing Rat Fractures. Calcified Tissue International, 88(2), 142-52. https://doi.org/10.1007/s00223-010-9439-z

Kragstrup, T. W., Kjaer, M. & Mackey, A. L. (2011). Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging. Scandinavian Journal of Medicine & Science in Sports Online, 21(6), 749-57. https://doi.org/10.1111/j.1600-0838.2011.01377.x

Yatime, L., Laursen, M., Morth, J. P., Esmann, M., Nissen, P. & Fedosova, N. (2011). Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. Journal of Structural Biology, 174, 296-306. https://doi.org/10.1016/j.jsb.2010.12.004

Yatime, L., Laursen, M., Morth, J. P., Esmann, M., Nissen, P. & Fedosova, N. U. (2011). Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. Journal of Structural Biology, 174(2), 296-306. https://doi.org/10.1016/j.jsb.2010.12.004

Li, Y., Zheng, H., Luo, R., Wu, H., Zhu, H., Li, R., Cao, H., Wu, B., Huang, S., Shao, H., Ma, H., Zhang, F., Feng, S., Zhang, W., Du, H., Tian, G., Li, J., Zhang, X., Li, S. ... Wang, J. (2011). Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly. Nature Biotechnology, 29(8), 723-30. https://doi.org/10.1038/nbt.1904

Gjesing, A. P., Nielsen, A. A., Brandslund, I., Christensen, C., Sandbæk, A., Jørgensen, T., Witte, D. R., Bonnefond, A., Froguel, P., Hansen, T. & Pedersen, O. (2011). Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes. B M C Medical Genetics, 12, 99. https://doi.org/10.1186/1471-2350-12-99

Kim, K.-J., Pearl, P. L., Jensen, K., Snead, O. C., Malaspina, P., Jakobs, C. & Gibson, K. M. (2011). Succinic semialdehyde dehydrogenase: biochemical-molecular-clinical disease mechanisms, redox regulation, and functional significance. Antioxidants & Redox Signaling, 15(3), 691-718. https://doi.org/10.1089/ars.2010.3470

Steinert, G., Oancea, C., Roos, J., Hagemeyer, H., Maier, T., Ruthardt, M. & Puccetti, E. (2011). Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα. PLOS ONE, 6(7), e22540. https://doi.org/10.1371/journal.pone.0022540

Jensen, M., Schmidt, S., Fedosova, N., Mollenhauer, J. & Jensen, H. H. (2011). Synthesis and Evaluation of Cardiac Glycosides Mimics as Potential Anticancer Drugs. Bioorganic & Medicinal Chemistry, 19, 2407-2417.

Bak, A. M., Egefjord, L., Jensen, M. G., Steffensen, C., Stecher, C. W., Smidt, K., Brock, B. & Rungby, J. (2011). Targeting amyloid-beta by glucagon-like peptide -1 (GLP-1) in Alzheimer's disease and diabetes. Expert Opinion On Therapeutic Targets, 15(10), 1153-62. https://doi.org/10.1517/14728222.2011.600691

Bak, R. O., Stenderup, K., Rosada, C., Petersen, L. B., Moldt, B., Dagnæs-Hansen, F., Jakobsen, M., Kamp, S., Jensen, T. G., Dam, T. N. & Mikkelsen, J. G. (2011). Targeting of human interleukin-12B by small hairpin RNAs in xenografted psoriatic skin. B M C Dermatology, 11(1), 5. https://doi.org/10.1186/1471-5945-11-5

Durinck, S., Ho, C., Wang, N. J., Liao, W., Jakkula, L. R., Collisson, E. A., Pons, J., Chan, S.-W., Lam, E. T., Chu, C., Park, K., Hong, S.-W., Hur, J. S., Huh, N., Neuhaus, I. M., Yu, S. S., Grekin, R. T., Mauro, T. M., Cleaver, J. E. ... Cho, R. J. (2011). Temporal dissection of tumorigenesis in primary cancers. Cancer Drug Discovery and Development, 1(2), 137-143. https://doi.org/10.1158/2159-8290.CD-11-0028

Melchjorsen, J., Risør, M. W., Søgaard, O. S., Oʼloughlin, K. L., Chow, S., Paludan, S. R., Ellermann-Eriksen, S., Hedley, D. W., Phd, H. M., Østergaard, L. J. & Tolstrup, M. (2011). Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12 / IL-10 balance in human primary cells. J A I D S, 57(4), 265-275. https://doi.org/10.1097/QAI.0b013e3182185276

Vandecaetsbeek, I., Christensen, S. B., Liu, H., Van Veldhoven, PP., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P. (2011). Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases. BBA General Subjects, 1813(5), 1118-27.

Vandecaetsbeek, I., Christensen, S. B., Liu, H., Van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P. (2011). Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases. BBA General Subjects, 1813(5), 1118-27. https://doi.org/10.1016/j.bbamcr.2010.12.020

Krass, M., Wegener, G., Vasar, E. & Volke, V. (2011). The antidepressant action of imipramine and venlafaxine involves suppression of nitric oxide synthesis. Behavioural Brain Research, 218(1), 57-63. https://doi.org/10.1016/j.bbr.2010.11.027

Kappelgaard, A.-M. & Laursen, T. (2011). The benefits of growth hormone therapy in patients with Turner syndrome, Noonan syndrome and children born small for gestational age. Growth Hormone & IGF Research, 21(6), 305-13. https://doi.org/10.1016/j.ghir.2011.09.004

Daugaard, H., Elmengaard, B., Andreassen, T. T., Baas, J., Bechtold, J. E. & Soballe, K. (2011). The combined effect of parathyroid hormone and bone graft on implant fixation. Journal of Bone and Joint Surgery: British Volume, 93(1), 131-9. https://doi.org/10.1302/0301-620X.93B1.24261

Middleton, D., Hughes, E. & Esmann, M. (2011). The conformation of ATP within the Na,K-ATPase nucleotide site from a statistically-constrained analysis of REDOR solid-state NMR data. Angewandte Chemie International Edition, 50(31), 7041-7044. https://doi.org/10.1002/anie.201100736

Martínez, V. G., Moestrup, S. K., Holmskov, U., Mollenhauer, J. & Lozano, F. (2011). The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis. Pharmacological Reviews, 63(4), 967-1000. https://doi.org/10.1124/pr.111.004523

Banke, T. G. (2011). The dilated TRPA1 channel pore state is blocked by amiloride and analogues. Brain Research, 1381, 21-30. https://doi.org/10.1016/j.brainres.2011.01.021

Bohn, A. B., Nederby, L., Harbo, T., Skovbo, A., Vorup-Jensen, T., Krog, J., Jakobsen, J. & Hokland, M. (2011). The effect of IgG levels on the number of natural killer cells and their Fc receptors in chronic inflammatory demyelinating polyradiculoneuropathy. European Journal of Neurology, 18(6), 919-924.

Orlowska, E. Z., Przybylowicz, W., Orlowski, D., Turnau, K. & Mejasz-Przybylowicz, J. (2011). The effect of mycorrhiza on the growth and elemental composition of Ni-hyperaccumulating plant Berkheya coddii Roessler. Environmental Pollution, 159(12), 3730. https://doi.org/10.1016/j.envpol.2011.07.008

Shortt, C., McMorrow, C., Fredsted, A., Jones, J., Bradford, A. & O'Halloran, K. (2011). The effects of chronic sustained and intermittent hypoxia on muscle physiology..

Ding, M., Danielsen, C. C. & Overgaard, S. (2011). The effects of glucocorticoid on microarchitecture, collagen, mineral and mechanical properties of sheep femur cortical bone. Journal of Tissue Engineering and Regenerative Medicine. https://doi.org/10.1002/term.448, https://doi.org/10.1002/448

Pietsch, J., Bauer, J., Egli, M., Infanger, M., Wise, P., Ulbrich, C. & Grimm, D. (2011). The effects of weightlessness on the human organism and mammalian cells. Current Molecular Medicine, 11(5), 350-64.

Poulsen, K., Tettelin, H. & Kilian, M. (2011). The Aggregatibacter Actinomycetemcomitans Genome: Diversity of Pathogenic Potential. In P. E. Kolenbrander (Ed.), Oral Microbial Communities: Genomic inquiry and interspecies communication (pp. 103-117). ASM Press.

Nexø, B. A., Christensen, T., Frederiksen, J., Møller-Larsen, A., Oturai, A. B., Villesen, P., Hansen, B., Nissen, K. K., Laska, M. J., Petersen, T. S., Bonnesen, S., Hedemand, A., Wu, T., Wang, X., Zhang, X., Brudek, T., Maric, R., Søndergaard, H., Sellebjerg, F. T. ... Pedersen, F. S. (2011). The Etiology of Multiple Sclerosis: Genetic Evidence for the Involvement of the Human Endogenous Retrovirus HERV-Fc1. P L o S One, 6(2), e16652. https://doi.org/10.1371/journal.pone.0016652

Vangsted, A. J., Klausen, T. W., Gimsing, P., Abildgaard, N., Andersen, N. F., Gregersen, H., Nexø, B. A. & Vogel, U. B. (2011). The importance of a sub-region on chromosome 19q13.3 for prognosis of multiple myeloma patients after high-dose treatment and stem cell support: a linkage disequilibrium mapping in RAI and CD3EAP. Annals of Hematology, 90(6), 675-84. https://doi.org/10.1007/s00277-010-1105-z

Losson, R., Nielsen, A. L. & Nielsen, A. L. (2011). The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation. BBA General Subjects, 1799(5-6), 463-8. https://doi.org/10.1016/j.bbagrm.2010.02.003

Buttenschøn, H. N., Kristensen, A. S., Buch, H. N., Andersen, J. H., Bonde, J. P., Grynderup, M., Hansen, A. M., Kolstad, H., Kaergaard, A., Kaerlev, L., Mikkelsen, S., Thomsen, J. F., Koefoed, P., Erhardt, A., Woldbye, D. P. D., Børglum, A. D. & Mors, O. (2011). The norepinephrine transporter gene is a candidate gene for panic disorder. Journal of neural transmission (Vienna, Austria : 1996), 118(6), 969-976. https://doi.org/10.1007/s00702-011-0624-7

Arnou, B., Montigny, C., Morth, J. P., Nissen, P., Jaxel, C., Møller, J. V. & Maire, M. L. (2011). The Plasmodium falciparum Ca(2+)-ATPase PfATP6: insensitive to artemisinin, but a potential drug target. Biochemical Society. Transactions, 39(3), 823-31. https://doi.org/10.1042/BST0390823

Arnou, B. J.-P., Montigny, C., Morth, J. P., Nissen, P., Jaxel, C., Møller, J. V. & le Maire, M. (2011). The Plasmodium falsiparum Ca(2+)-ATPase PfATP6: insensitive to artemisin, but a potential drug target. Biochemical Society. Transactions, 39(3), 823-831.

Hansen, T. F., Sørensen, F. B. & Lindebjerg, J. (2011). The predictive value of miRNA in relation to first line capecitabine and oxaliplatin in patients with metastatic colorectal cancer.

Østergaard, J., Thiel, S., Hansen, T. K., Rasch, R. & Flyvbjerg, A. (2011). The role of complement C3 in the pathogenesis of diabetic kidney disease in a murine model of type 1 diabetes. Diabetes, e7.

Skovgaard, N., Gouliaev, A., Aalling, M. & Simonsen, U. (2011). The Role of Endogenous H(2)S in Cardiovascular Physiology. Current Pharmaceutical Biotechnology, 1385-1393.

Gjelstrup, L. C., Andersen, S. H., Petersen, S. V., Enghild, J. J., Blom, A. M., Vorup-Jensen, T. & Thiel, S. (2011). The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein. Molecular Immunology, 49(1-2), 38-47. https://doi.org/10.1016/j.molimm.2011.07.018

Sørensen, M. V., Strandsby, A. B., Larsen, C. K., Prætorius, H. & Leipziger, J. G. (2011). The secretory K_Ca1.1 channel localises to crypts of distal mouse colon: functional and molecular evidence. Pflügers Archiv - European Journal of Physiology, 462, 745-752.

Martuseviciene, G., Hofman-Bang, J., Clausen, T., Olgaard, K. & Lewin, E. (2011). The secretory response of parathyroid hormone to acute hypocalcemia in vivo is independent of parathyroid glandular sodium/potassium-ATPase activity. Kidney International, 79, 742-748.

Richner, M., Bjerrum, O. J., Nykjær, A. & Vægter, C. B. (2011). The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice. Journal of Visualized Experiments, 54. http://www.jove.com/details.php?id=3092

Köhler, C., Lighthouse, J. K., Werther, T., Andersen, O. M., Diehl, A., Schmieder, P., Du, J., Holdener, B. C. & Oschkinat, H. (2011). The structure of MESD45-184 brings light into the mechanism of LDLR family folding. Structure, 19(3), 337-48. https://doi.org/10.1016/j.str.2010.12.022

Brinkmann, C. R., Heegaard, C. W., Petersen, T. E., Jensenius, J. C. & Thiel, S. (2011). The toxicity of bovine α-lactalbumin made lethal to tumor cells is highly dependent on oleic acid and induces killing in cancer cell lines and noncancer-derived primary cells. FEBS journal, 278(11), 1955-67. https://doi.org/10.1111/j.1742-4658.2011.08112.x

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