Peer-reviewed publications

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Grarup, N., Andreasen, C. H., Andersen, M. K., Albrechtsen, A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, O. B. (2008). The -250G>A promoter variant in hepatic lipase (LIPC) associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. Journal of Clinical Endocrinology and Metabolism, 93(6), 2294-9.

Pedersen, C. B., Kølvraa, S., Kølvraa, A., Stenbroen, V., Kjeldsen, M., Ensenauer, R., Tein, I., Matern, D., Rinaldo, P., Vianey-Saban, C., Ribes, A., Lehnert, W., Christensen, E., Corydon, T. J., Andresen, B. S., Vang, S., Bolund, L., Vockley, J., Bross, P. & Gregersen, N. (2008). The ACADS gene variation spectrum in 114 patients with short-chain acyl-CoA dehydrogenase (SCAD) deficiency is dominated by missense variations leading to protein misfolding at the cellular level. Human Genetics, 124(1), 43-56. https://doi.org/10.1007/s00439-008-0521-9

Schiffmann, S., Maier, T., Wobst, I., Janssen, A., Corban-Wilhelm, H., Angioni, C., Geisslinger, G. & Grösch, S. (2008). The anti-proliferative potency of celecoxib is not a class effect of coxibs. Biochemical Pharmacology, 76(2), 179-87. https://doi.org/10.1016/j.bcp.2008.04.017

Wang, J., Wang, W., Li, R., Li, Y., Tian, G., Goodman, L., Fan, W., Zhang, J., Li, J., Zhang, J., Guo, Y., Feng, B., Li, H., Lu, Y., Fang, X., Liang, H., Du, Z., Li, D., Zhao, Y. ... Wang, J. (2008). The diploid genome sequence of an Asian individual. Nature, 456(7218), 60-5. https://doi.org/10.1038/nature07484

Petersen, A. H., Kohler, G., Korsatko, S., Wutte, A., Wonisch, M., Mautner, A., Rønn, B. B., Clauson, P., Laursen, T., Wollmer, P. & Pieber, T. R. (2008). The effect of exercise on the absorption of inhaled human insulin in healthy volunteers. British Journal of Clinical Pharmacology, 65(2), 165-171.

Ding, M., Danielsen, C. C. & Hvid, I. (2008). The effects of bone remodeling inhibition by alendronate on 3-D microarchitecture of subchondral bone tissues in guinea pig primary osteoarthrosis. Calcified Tissue International, 82(1), 77-86.

Lehtonen, S., Shah, M., Nielsen, R., Iino, N., Ryan, J. J., Zhou, H. & Farquhar, M. G. (2008). The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis. Molecular Biology of the Cell, 19(7), 2949-61. https://doi.org/10.1091/mbc.E07-05-0521

Kragstrup, T. W., Otkjaer, K., Holm, C., Jørgensen, A., Hokland, M., Iversen, L. & Deleuran, B. W. (2008). The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. Cytokine, 41(1), 16-23. https://doi.org/10.1016/j.cyto.2007.10.004

Goldbaum, O., Jensen, P. H. & Richter-Landsberg, C. (2008). The expression of tubulin polymerization promoting protein TPPP/p25α is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress. Glia, 56, 1736-1746.

Petersen, S. V., Kristensen, T., Petersen, J. S., Ramsgaard, L., Oury, T., Crapo, J., Nielsen, N. C. & Enghild, J. J. (2008). The folding of human active and inactive extracellular superoxide dismutase is an intracellular event. Journal of Biological Chemistry, 283(22), 15031. https://doi.org/10.1074/jbc.M801548200

Seedorf, H., Fricke, W. F., Veith, B., Brüggemann, H., Liesegang, H., Strittmatter, A., Miethke, M., Buckel, W., Hinderberger, J., Li, F., Hagemeier, C., Thauer, R. K. & Gottschalk, G. (2008). The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features. Proceedings of the National Academy of Sciences (PNAS), 105(6), 2128-33. https://doi.org/10.1073/pnas.0711093105

Bross, P., Naundrup, S., Hansen, J., Nielsen, M. N., Christensen, J. H., Kruhøffer, M., Palmfeldt, J., Corydon, T. J., Gregersen, N., Ang, D., Georgopoulos, C. & Nielsen, K. L. (2008). The Hsp60-(p.V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo. Journal of Biological Chemistry, 283(23), 15694-700. https://doi.org/10.1074/jbc.M800548200

Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, J. D. (2008). The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42. Gene Expression Patterns, 1227, 240-7. https://doi.org/10.1016/j.brainres.2008.06.062

Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, J. D. (2008). The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice oxerexpressing human amyloid-beta 1-42. Brain Research, 1227, 240-47.

Jayatissa, M. N., Bisgaard, C., West, M. J. & Wiborg, O. (2008). The number of granule cells in rat hippocampus is reduced after chronic mild stress and re-established after chronic escitalopram treatment. Neuropharmacology, 54(3). https://doi.org/10.1016/j.neuropharm.2007.11.009

Marques, J., Anwar, J., Eskildsen-Larsen, S., Rebouillat, D., Paludan, S. R., Sen, G., Williams, B. R. G. & Hartmann, R. (2008). The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain. Journal of General Virology, 89(Pt 11), 2767-72. https://doi.org/10.1099/vir.0.2008/003558-0

Jensen, K. H., Aalkjær, C., Lambert, J. D. C., Hessellund, A. & Bek, T. (2008). The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition. Acta Ophthalmologica, 86, 26-33.

Watson, P., Vasen, H. FA., Mecklin, J.-P., Aarnio, M., Järvinen, H., Myrhøj, T., Sunde, L., Wijnen, JT. & Lynch, H. T. (2008). The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. International Journal of Cancer, 123(2), 444-9.

Pedersen, M. Ø., Larsen, A., Stoltenberg, M. & Penkowa, M. (2008). The role of metallothionein in oncogenesis and cancer prognosis. Progress in Histochemistry and Cytochemistry, 44(1), 29-64. https://doi.org/10.1016/j.proghi.2008.10.001

Christoffersen, C., Ahlström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B. (2008). The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma. Journal of Biological Chemistry, 283, 18765-18772. https://doi.org/10.1074/jbc.M800695200

Sørensen, L. N., Reinert, L. S., Malmgaard, L., Bartholdy, C., Thomsen, A. R. & Paludan, S. R. (2008). TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain. Journal of Immunology, 181(12), 8604-12.

Sørensen, L. N., Reinert, L., Malmgaard, L., Bartholdy, C., Thomsen, A. R. & Paludan, S. R. (2008). TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain. Journal of Immunology, 181, 8604-12.

Banke, T. G. & Gegelashvili, G. (2008). Tonic activation of group I mGluRs modulates inhibitory synaptic strength by regulating KCC2 activity. The Journal of Physiology, 586(Pt 20), 4925-34. https://doi.org/10.1113/jphysiol.2008.157024

Hindré, T., Brüggemann, H., Buchrieser, C. & Héchard, Y. (2008). Transcriptional profiling of Legionella pneumophila biofilm cells and the influence of iron on biofilm formation. Microbiology, 154(Pt 1), 30-41. https://doi.org/10.1099/mic.0.2007/008698-0

Christensen, R., Alsner, J., Sørensen, F. B., Dagnaes-Hansen, F., Kolvraa, S. & Serakinci, N. (2008). Transformation of human mesenchymal stem cells in radiation carcinogenesis: long-term effect of ionizing radiation. Regenerative Medicine, 3(6), 849-61. https://doi.org/10.2217/17460751.3.6.849

Mansilla, F., Dominguez, C. A. G., Yeadon, J. E., Corydon, T. J., Burden, S. J. & Knudsen, C. R. (2008). Translation elongation factor eEF1A binds to a novel myosin binding protein-C-like protein. Molecular and Cellular Biology, 105(3), 847-858.

Graversen, J. H., Laurberg, J. M., Andersen, M. H., Falk, E., Nieland, J., Christensen, J., Etzerodt, M., Thøgersen, H. C. & Moestrup, S. K. (2008). Trimerization of apolipoprotein A-I retards plasma clearance and preserves antiatherosclerotic properties. Journal of Cardiovascular Pharmacology, 51(2), 170-177.

Laursen, H. B., Kannerup, A.-S., Oxlund, H., Yasuda, Y., Funch-Jensen, P., Rokkjaer, M. & Mortensen, F. V. (2008). T-tube drainage stimulates the healing of choledocho-choledochostomies. An experimental study in pigs. Journal of Hepato - Biliary - Pancreatic Surgery, 15(6), 622-6. https://doi.org/10.1007/s00534-007-1322-6

Niemann, I., Bolund, L. & Sunde, L. (2008). Twin pregnancies with diploid hydatidiform mole and co-existing normal fetus may originate from one oocyte. Human Reproduction, 23(9), 2031-5. https://doi.org/10.1093/humrep/den226

Andersen, C. Y., Rosendahl, M., Byskov, A. G., Loft, A., Ottosen, C., Dueholm, M., Schmidt, K. L. T., Andersen, A. N. & Ernst, E. (2008). Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Human Reproduction, 23(10), 2266-72. https://doi.org/10.1093/humrep/den244

Gailly, P., Jouret, F., Martin, D., Cosyns, J.-P., Nishita, T., Antignac, C., Willnow, T. E., Courtoy, P. J., Scheinman, S. J., Christensen, E. I. & Devuyst, O. (2008). Type III Carbonic Anhydrase: A Novel Renal Isoform that Plays a Role in Proximal Tubule Dysfunction. Kidney International, 74, 52-61.

Thisted, H., Johnsen, S. P., Søndergaard, F. & J., R. (2008). Type of preadmission glucose-lowering treatment and prognosis among patients hospitalised with myocardial infarction: a nationwide follow-up study. Diabetologia, 51, 567-574.

Kristiansen, S., Ifversen, P. & Danscher, G. (2008). Ultrastructural localization and chemical binding of silver ions in human organotypic skin cultures. Histochemistry and Cell Biology, 130(1), 177-184.

Maddika, S., Panigrahi, S., Wiechec, E., Wesselborg, S., Fischer, U., Schulze-Osthoff, K. & Los, M. (2008). Unscheduled Akt-triggered activation of CDK2 as a key effector mechanism of apoptin's anticancer toxicity. Molecular and Cellular Biology.

Capasso, G., Rizzo, M., Garavaglia, M. L., Trepiccione, F., Zacchia, M., Mugione, A., Ferrari, P., Paulmichl, M., Lang, F., Loffing, J., Carrel, M., Damiano, S., Wagner, C. A., Bianchi, G. & Meyer, G. (2008). Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension. American Journal of Physiology: Renal Physiology, 295(2), F556-67. https://doi.org/10.1152/ajprenal.00340.2007

Wang, G., Li, C., Kim, SW., Ring, T., Wen, J., Djurhuus, J. C., Wang, W., Nielsen, S. & Frøkiær, J. (2008). Ureter obstruction alters expression of renal acid-base transport proteins in rat kidney. American Journal of Physiology: Renal Physiology, 295(2), 497-506.

Wilmer, M. J., Christensen, E. I., van den Heuvel, L. P., Monnens, L. A. & Levtchenko, E. A. (2008). Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. American Journal of Kidney Diseases, 51, 893-903.

Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, H., Sørensen, T. I. A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, O. & Hansen, T. (2008). Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes. Diabetes. https://doi.org/10.2337/db08-0620

Infanger, M., Grosse, J., Westphal, K., Leder, A., Ulbrich, C., Paul, M. & Grimm, D. (2008). Vascular endothelial growth factor induces extracellular matrix proteins and osteopontin in the umbilical artery. Annals of Vascular Surgery, 22(2), 273-84. https://doi.org/10.1016/j.avsg.2007.11.002

Bødtkjer, D. M. B., Matchkov, V., Bødtkjer, E., Nilsson, H. & Aalkjær, C. (2008). Vasomotion has chloride-dependency in rat mesenteric small arteries. Pflügers Archiv - European Journal of Physiology, 457(2), 389-404. https://doi.org/10.1007/s00424-008-0532-3

Hoffert, J. D., Fenton, R., Møller, H., Simons, B., Tchapyjnikov, D., McDill, B. W., Yu, M.-J., Pisitkun, T., Chen, F. & Knepper, M. A. (2008). Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2. Journal of Biological Chemistry, 283(36), 24617-27. https://doi.org/10.1074/jbc.M803074200

Eriksen, J., Rasmussen, S. G. F., Rasmussen, T. N., Vægter, C. B., Cha, J. H., Zou, M.-F., Newman, A. H. & Rasmussen, T. N. (2008). Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogues. Journal of Neuroscience, 29(21), 6798-6808.

Willnow, T. E., Petersen, C. M. & Nykjær, A. (2008). VPs10p-domain receptors . central regulators of neuronal viability. Nature Reviews. Neuroscience, 9, 899-909.

Chi, Z.-H., Wang, X., Cai, J.-Q., Stoltenberg, M., Danscher, G. & Wang, Z.-Y. (2008). Zinc transporter 3 immunohistochemistochemical tracing of sprouting mossy fibres. Neurochemistry International, 52(7), 1305-1309.

Simonsen, U., Laursen, B. E. & Petersen, J. S. (2008). ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. British Journal of Pharmacology, 153(6), 1185-94. https://doi.org/10.1038/sj.bjp.0707688

Lee, YJ., Choi, HJ., Lim, JS., Earm, JH., Bee, BH., Kim, IS., Frøkiær, J., Nielsen, S. & Kwon, TH. (2008). A novel method of ligand peptidomics to identify peptide ligands binding to AQP2-expressing plasma membranes and intracellular vesicles of rat kidney. . American Journal of Physiology: Renal Physiology, 295(1), 300-309.

Doi, K., Hu, X., Yuen, PS., Leelahavanichkul, A., Yasuda, H., Kim, SM., Schnermann, J., Jonassen, TE., Frøkiær, J. & Nielsen, S. (2008). AP214, an analouge of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced actute kidney injury and mortality. Kidney International, 73(11), 1266-1274.

Huebener, N., Fest, S., Strandsby, A. B., Michalsky, E., Preissner, R., Zeng, Y., Gaedicke, G. & Lode, H. N. (2008). A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity. Molecular Cancer Therapeutics, 7, 2241-2251. https://doi.org/10.1158/1535-7163.MCT-08-0109

Kleinnijenhuis, A. J., Hedegaard, C., Lundvig, D. M. S., Sundbye, S., Issinger, O. G., Nørregaard Jensen, O. & Jensen, P. H. (2008). Identification of multiple posttranslational modifications in the porcine brain specific p25α. Journal of Neurochemistry, 1006, 925-933.

Nørregaard, R., Bødker, T., Jensen, BL., Stødkilde-Jørgensen, L., Nielsen, S. & Frøkiær, J. (2008). Increased renal adrenomedullin expression in rats with ureteral obstruction. American Journal of Physiology: Renal Physiology.

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