Peer-reviewed publications

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Wittenborn, T. R., Nielsen, T., Thomsen, J. S., Horsman, M. R. & Nygaard, J. V. (2016). Simulation of heterogeneous molecular delivery in tumours using μCT reconstructions and MRI validation. Microvascular Research, 108, 69-74. https://doi.org/10.1016/j.mvr.2016.08.004

Bayley, J. S., Pedersen, T. H. & Nielsen, O. B. (2016). Skeletal muscle dysfunction in the db/db mouse model of type 2 diabetes. Muscle & Nerve, 54(3), 460-8. https://doi.org/10.1002/mus.25064

Ishima, Y., Kragh-Hansen, U. & Otagiri, M. (2016). S-Nitroso Adducts of Albumin Analogs: Characterization, Categorization, and Possible Future Therapeutic Applications. In M. Otagiri & V. T. Giam Chuang (Eds.), Albumin in Medicine: Pathological and Clinical Applications (pp. 147-164). Springer.

Røder, M. E., Storgaard, H., Rungby, J., Knop, F. K. & Vilsbøll, T. (2016). Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes. Ugeskrift for Læger, 178(38).

Molgaard, S., Demontis, D., Nicholson, A. M., Finch, N. A., Petersen, R. C., Petersen, C. M., Rademakers, R., Nykjaer, A. & Glerup, S. (2016). Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals. Experimental Gerontology, 84, 96-100. https://doi.org/10.1016/j.exger.2016.09.002

Glerup, S., Bolcho, U., Bøggild, S., Vaegter, C. B., Smith, A. H., Nieto-Gonzalez, J. L., Ovesen, P. L., Pedersen, L. F., Fjorback, A. N., Kjolby, M., Login, H., Holm, M. M., Andersen, O. M., Nyengaard, J. R., Willnow, T. E., Jensen, K., Nykjaer, A. & Jensen, S. M. (2016). SorCS2 is required for BDNF-dependent plasticity in the hippocampus. Molecular Psychiatry, 21(12), 1740-1751. https://doi.org/10.1038/mp.2016.108

Goettsch, C., Hutscheson, JD., Aikawa, M., Iwata, H., Pham, T., Nykjær, A., Kjølby, M. F., Rogers, M., Michel, T., Shibasaki, M., Hagita, S., Kramann, R., Rader, D. J., Libby, P., Singh, SA. & Aikawa, E. (2016). Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. Journal of Clinical Investigation, 126(4), 1323.

Bathia, T., Cornelius, F., Brewer, J., Bagatolli, LA., Simonsen, AC., Ipsen, JH. & Mouritsen, O. G. (2016). Spatial distribution and activity of Na,K-ATPase in lipid bilayer membranes with phase boundaries. BBA Biomembranes, 1858(6), 1390-1399.

Boggild, S., Molgaard, S., Glerup, S. & Nyengaard, J. R. (2016). Spatiotemporal patterns of sortilin and SorCS2 localization during organ development. B M C Cell Biology, 17(1), 8. Article 8. https://doi.org/10.1186/s12860-016-0085-9

Matchkov, V. & Krivoi, II. (2016). Specialized Functional Diversity and Interactions of the Na,K-ATPase. Frontiers in Physiology, 7(MAY), Article 179. https://doi.org/10.3389/fphys.2016.00179

Meier, S. M., Uher, R., Mors, O., Dalsgaard, S., Munk-Olsen, T., Laursen, T. M., Mattheisen, M., Nordentoft, M., Mortensen, P. B. & Pavlova, B. (2016). Specific anxiety disorders and subsequent risk for bipolar disorder: a nationwide study. World Psychiatry, 15(2), 187-188. https://doi.org/10.1002/wps.20314

Rasmussen, R. & Carlsen, E. M. (2016). Spontaneous Functional Recovery from Incomplete Spinal Cord Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(33), 8535-7. https://doi.org/10.1523/JNEUROSCI.1684-16.2016

Willerslev-Olsen, A., Krejsgaard, T., Lindahl, L. M., Litvinov, I. V., Fredholm, S., Petersen, D. L., Nastasi, C., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Bonefeld, C. M., Geisler, C., Woetmann, A., Iversen, L., Kilian, M., Koralov, S. & Odum, N. (2016). Staphylococcus aureus enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma. Blood, 127(10), 1287-96. https://doi.org/10.1182/blood-2015-08-662353

Thingholm, L. B., Andersen, L., Makalic, E., Southey, M. C., Thomassen, M. & Hansen, L. L. (2016). Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges. Frontiers in Genetics, 7(FEB), 1-13. Article 2.

Bach, E., Møller, A. B., Jørgensen, J. O. L., Vendelbo, M. H., Jessen, N., Pedersen, S. B., Nielsen, T. S. & Møller, N. (2016). Stress hormone release is a key component of the metabolic response to lipopolysaccharide (LPS): studies in hypopituitary and healthy subjects. Journal of Endocrinology, 175(5), 455-465. https://doi.org/10.1530/EJE-16-0444

Jensen, M. R., Bajic, G., Zhang, X., Laustsen, A. K., Koldsø, H., Skeby, K. K., Schiøtt, B., Andersen, G. R. & Vorup-Jensen, T. (2016). Structural basis for simvastatin competitive antagonism of complement receptor 3. Journal of Biological Chemistry, 291(33), 16963-16976. https://doi.org/10.1074/jbc.M116.732222

Schatz-Jakobsen, J. A., Pedersen, D. V. & Andersen, G. R. (2016). Structural insight into proteolytic activation and regulation of the complement system. Immunological Reviews, 274(1), 59-73. https://doi.org/10.1111/imr.12465

Diernaes, J. E. F., Hjuler, K. F., Kristensen, L. & Deleuran, M. (2016). Subcutaneous Phaeohyphomycosis due to Alternaria dennisii in a 85-year-old Immunocompromised Patient. Acta Dermato-Venereologica, 96(5), 701-702. https://doi.org/10.2340/00015555-2343

Dahlén, G., Luan, W.-M., Dahlgren, U., Papapanou, P. N., Baelum, V. & Fejerskov, O. (2016). Subgingival bacterial clusters and serum antibody response as markers of extent and severity of periodontitis in adult Chinese. European Journal of Oral Sciences, 124(2), 179-187. https://doi.org/10.1111/eos.12256

Jensen, J. B., Sundelin, E. I., Jakobsen, S., Gormsen, L. C., Munk, O. L., Frøkiær, J. & Jessen, N. (2016). [ ¹¹C]-labeled metformin distribution in the liver and small intestine using dynamic positron emission tomography in mice demonstrates tissue-specific transporter dependency. Diabetes, 65(6), 1724-1730. https://doi.org/10.2337/db16-0032

Heftdal, L. D., Hvid, M., Deleuran, B. & Kragstrup, T. W. (2016). SYNOVIAL MYOFIBROBLASTS FROM SPONDYLOARTHRITIS PATIENTS PRODUCE IL-26 SPONTANEOUSLY AND THE PRODUCTION IS ENHANCED UPON IL-1, TNF-alpha AND LPS STIMULATION. Annals of the Rheumatic Diseases, 75, 84-84. https://doi.org/10.1136/annrheumdis-2016-eular.4585

Vegger, J. B., Brüel, A., Sørensen, T. G. & Thomsen, J. S. (2016). Systemic Treatment with Strontium Ranelate Does Not Influence the Healing of Femoral Mid-shaft Defects in Rats. Calcified Tissue International, 98(2), 206-14. https://doi.org/10.1007/s00223-015-0077-3

Cai, Y., Laustsen, A., Zhou, Y., Sun, C., Anderson, M. V., Li, S., Uldbjerg, N., Luo, Y., Jakobsen, M. R. & Mikkelsen, J. G. (2016). Targeted, homology-driven gene insertion in stem cells by ZFN-loaded 'all-in-one' lentiviral vectors. eLife, 5(JUN2016), Article e12213. https://doi.org/10.7554/eLife.12213

Richner, M., Vægter, C. B. & Pallesen, L. T. (2016). Targeting glial dysfunction to treat post-surgical neuropathic pain. Scandinavian Journal of Pain, 10, 58-60.

Rohde, P. D., Madsen, L. S., Arvidson, S. M. N., Loeschcke, V., Demontis, D. & Kristensen, T. N. (2016). Testing candidate genes for attention-deficit/hyperactivity disorder in fruit flies using a high throughput assay for complex behavior. Fly, 10(1), 25-34. Article 1158365. https://doi.org/10.1080/19336934.2016.1158365

Amdisen, C., Keller, A. K., Hansen, R. S., Nørregaard, R., Krag, S. R. P., Møldrup, U., Pedersen, M., Jespersen, B. & Birn, H. (2016). Testing Danegaptide Effects on Kidney Function after Ischemia/Reperfusion Injury in a New Porcine Two Week Model. P L o S One, 11(10), Article e0164109. https://doi.org/10.1371/journal.pone.0164109

Tvilling, L., Glud, A. N., Jan, J., Orlowski, D., Ettrup, K. S., Bender, D., Petersen, M., Bjarkam, C., West, M. J. & Sorensen, J. C. (2016). The anatomy and neurohistology of the minipig pituitary. Poster session presented at Neuroscience Day 2016, Aarhus, Denmark.

Zhang, X., Bajic, G., Andersen, G. R., Christiansen, S. H. & Vorup-Jensen, T. (2016). The cationic peptide LL-37 binds Mac-1 (CD11b/CD18) with a low dissociation rate and promotes phagocytosis. B B A - Proteins and Proteomics, 1864(5), 471-478. https://doi.org/10.1016/j.bbapap.2016.02.013

Laursen, T. L., Støy, S., Deleuran, B., Vilstrup, H., Grønbaek, H. & Sandahl, T. D. (2016). The damage-associated molecular pattern HMGB1 is elevated in human alcoholic hepatitis, but does not seem to be a primary driver of inflammation. Acta Pathologica et Microbiologica Scandinavica APMIS, 124(9), 741-7. https://doi.org/10.1111/apm.12568

Brüggemann, H. (2016). The emerging role of propionibacteria in human health and disease. In The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology (pp. 199-214). John Wiley & Sons.

Depner, M., Fuchs, S., Raabe, J., Frede, N., Glocker, C., Doffinger, R., Gkrania-Klotsas, E., Kumararatne, D., Atkinson, T. P., Schroeder, H. W., Niehues, T., Dückers, G., Stray-Pedersen, A., Baumann, U., Schmidt, R., Franco, J. L., Orrego, J., Ben-Shoshan, M., McCusker, C. ... Grimbacher, B. (2016). The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1. Journal of Clinical Immunology, 36(1), 73-84. https://doi.org/10.1007/s10875-015-0214-9

Overgaard-Steensen, C., Stødkilde-Jørgensen, H., Larsson, A., Tønnesen, E., Frøkiaer, J. & Ring, T. (2016). The frequently used intraperitoneal hyponatraemia model induces hypovolaemic hyponatraemia with possible model-dependent brain sodium loss. Experimental Physiology, 101.7(7), 932-945. https://doi.org/10.1113/EP085751

Brøchner, A. C., Mikkelsen, S., Hegelund, I., Hokland, M., Mogensen, O. & Toft, P. (2016). The immune response is affected for at least three weeks after extensive surgery for ovarian cancer. Danish Medical Journal, 63(6), 1-5. Article A5243. http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2016/DMJ_2016_06/A5243

de Vries, N. L., Swets, M., Vahrmeijer, A. L., Hokland, M. & Kuppen, P. J. K. (2016). The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment. International Journal of Molecular Sciences , 17(7). https://doi.org/10.3390/ijms17071030

Wehland, M., Warnke, E., Frett, T., Hemmersbach, R., Hauslage, J., Ma, X., Aleshcheva, G., Pietsch, J., Bauer, J. & Grimm, D. (2016). The Impact of Hypergravity and Vibration on Gene and Protein Expression of Thyroid Cells. Microgravity - Science and Technology, 28(3), 261-274. https://doi.org/10.1007/s12217-015-9474-5

Grimm, D., Grosse, J., Wehland, M., Mann, V., Reseland, J. E., Sundaresan, A. & Corydon, T. J. (2016). The impact of microgravity on bone in humans. Bone, 87, 44-56. https://doi.org/10.1016/j.bone.2015.12.057

Bieghs, L., Johnsen, H. E., Maes, K., Menu, E., Van Valckenborgh, E., Overgaard, M. T., Nyegaard, M., Conover, C. A., Vanderkerken, K. & De Bruyne, E. (2016). The insulin-like growth factor system in Multiple Myeloma: diagnostic and therapeutic potential. OncoTarget, 7(30), 48732-48752. https://doi.org/10.18632/oncotarget.8982

Kragstrup, T. W., Greisen, S. R., Nielsen, M. A., Rhodes, C., Stengaard-Pedersen, K., Hetland, M. L., Hørslev-Petersen, K., Junker, P., Østergaard, M., Hvid, M., Vorup-Jensen, T., Robinson, W. H., Sokolove, J. & Deleuran, B. (2016). The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression. Arthritis research & therapy, 18(1), Article 61. https://doi.org/10.1186/s13075-016-0964-7

Jensen, A. B., Ennibi, O. K., Ismaili, Z., Poulsen, K. & Haubek, D. (2016). The JP2 genotype of Aggregatibacter actinomycetemcomitans and marginal periodontitis in the mixed dentition. Journal of Clinical Periodontology, 43(1), 19-25. http://onlinelibrary.wiley.com/doi/10.1111/jcpe.12486/epdf

Vorup-Jensen, T. (2016). The Nanoscience of Polyvalent Binding by Proteins in the Immune Response. In K. Howard, T. Vorup-Jensen & D. Peer (Eds.), Nanomedicine (pp. 53-76). Springer.

Scholz, C. F. P. & Kilian, M. (2016). The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov. International Journal of Systematic and Evolutionary Microbiology, 66(11), 4422-4432. Article 001367. https://doi.org/10.1099/ijsem.0.001367

Ingels, C., Vanhorebeek, I., Derese, I., Jensen, L., Wouters, P. J., Thiel, S. & Van den Berghe, G. (2016). The pattern recognition molecule collectin-L1 in critically ill children. Pediatric Research, 80(2), 237-43. https://doi.org/10.1038/pr.2016.76

Thomsen, J. S., Andreasen, C. M., Bakalova, L. P., Brüel, A., Hauge, E. M., Eschen, G. E. T., Kiil, B. J., Delaisse, J.-M., Kersh, M. E. & Levin Andersen, T. (2016). The radial distribution of the intracortical porosity within the fibula diaphysis. Poster session presented at Annual meating American Society of Bone and Mineral Research, Atlanta, Georgia, United States.

Meidahl, A. C., Orlowski, D., Sørensen, J. C. H. & Bjarkam, C. R. (2016). The Retrograde Connections and Anatomical Segregation of the Göttingen Minipig Nucleus Accumbens. Frontiers in Neuroanatomy, 10(DEC), 117. Article 117. https://doi.org/10.3389/fnana.2016.00117

Jakobsen, K. R., Demuth, C., Sorensen, B. S. & Nielsen, A. L. (2016). The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Translational Lung Cancer Research, 5(2), 172-82. https://doi.org/10.21037/tlcr.2016.04.07

Holm, K., Bank, S., Nielsen, H., Kristensen, L. H., Prag, J. & Jensen, A. (2016). The role of Fusobacterium necrophorum in pharyngotonsillitis - A review. Anaerobe, 42, 89-97. https://doi.org/10.1016/j.anaerobe.2016.09.006

Comuth, W., Münster, A.-M. B., Damiana, T., Henriksen, L. Ø., Husted, S., van de Kerkhof, D., Faaborg, L. & Maat, M. D. (2016). The stability of dabigatran-spiked plasma after storage at -80ºC. Abstract from Eurothrombosis 2016, London, United Kingdom.

Saederup, K. L., Stødkilde-Jørgensen, K., Graversen, J. H., Dickson, C. F., Etzerodt, A., Hansen, S. W. K., Fago, A., Gell, D., Andersen, C. B. F. & Moestrup, S. K. (2016). The Staphylococcus aureus Protein IsdH Inhibits Host Hemoglobin Scavenging to Promote Heme Acquisition by the Pathogen. Journal of Biological Chemistry, 291(46), 23989-23998. https://doi.org/10.1074/jbc.M116.755934

Hansen, S. N., Ehlers, N. S., Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, J., Ditzel, H. J., Brünner, N., Schrohl, A.-S., Stenvang, J. & Gupta, R. (2016). The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells. B M C Genomics, 17(1), 442. Article 442. https://doi.org/10.1186/s12864-016-2749-4

Smerup, M. H., Damkjær, M., Brøndum, E., Baandrup, U. T., Kristiansen, S. B., Nygaard, H., Aalkjær, C., Sauer, C., Buchanan, R., Bertelsen, M. F., Østergaard, K. H., Grøndahl, C., Candy, G., Hasenkam, J. M., Secher, N. H., Bie, P. & Wang, T. (2016). The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output. Journal of Experimental Biology, 49(3), 457-63. https://doi.org/10.1242/jeb.132753

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