Peer-reviewed publikationer

Peer-reviewed publications

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Pedersen, C. V. B., Østergaard, L., Mogensen, T., Paludan, S. R. & Bertelsen, L. S. (2007). Toll-like receptorer, nye behandlingsstrategier? Ugeskrift for Læger, 169(23), 2193-8.

Babcock, A., Wirenfeldt, M., Holm, T., Nielsen, H. H., Dissing-Olesen, L., Toft-Hansen, H., Millward, J. M., Landmann, R., Rivest, S., Finsen, B., Owens, T. & Holm, T. H. (2006). Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation. Journal of Neuroscience, 26(49), 12826-37. https://doi.org/10.1523/JNEUROSCI.4937-05.2006

Kragstrup, T. W., Andersen, T., Holm, C., Schiøttz-Christensen, B., Jurik, A. G., Hvid, M. & Deleuran, B. (2015). Toll-like receptor 2 and 4 induced IL-19 dampens immune reactions and associates inversely with spondyloarthritis disease activity. Clinical and Experimental Immunology, 180(2), 233-242. https://doi.org/10.1111/cei.12577

Paludan, S. R., Levy, O. & Bowie, A. G. (2011). Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake. Nature Immunology, 12(9), 805-8. https://doi.org/10.1038/ni.0911-805

Isidor, S., Laursen, T. L., Bundgaard, H., Sædder, E. A. & Helgestad, O. K. (2023). Toksisk forbrug af baclofen med kramper ved udtrapning. Ugeskrift for Læger, 185(13), Artikel V09220530.

Hagn-Meincke, R., Frøkjær, J. B., Drewes, A. M., Holmboe, C. H., Krogh, K., Nedergaard, R. B., Davidsen, L., Okdahl, T., Haldorsen, I. S., Park, W., Deleuran, B. W. & Olesen, S. S. (2025). Tocilizumab for Painful Chronic Pancreatitis (TOPAC trial): Protocol for a phase 2 randomized, placebo-controlled, double-blind, investigator-initiated trial. Pancreatology, 25(3), 343-352. https://doi.org/10.1016/j.pan.2025.03.001

Skott, M., Andreassen, T. T., Ulrich-Vinther, M., Chen, X., Keyler, D. E., LeSage, M. G., Pentel, P. R., Bechtold, J. E. & Søballe, K. (2006). Tobacco Extract but Not Nicotine Impairs the Mechanical Strength of Fracture Healing in Rats. Journal of Orthopaedic Research, 24, 1472-1479.

Guan, X., Zhang, B. & Sun, L. (2022). TNFR2 is a regulatory target of pol-miR-194a and promotes the antibacterial immunity of Japanese flounder Paralichthys olivaceus. Developmental and Comparative Immunology, 135, Artikel 104477. https://doi.org/10.1016/j.dci.2022.104477

Dam, V. S., Bødtkjer, D. M. B., Nyvad, J. T., Aalkjær, C. & Matchkov, V. (2014). TMEM16A knockdown abrogates two different Ca(2+)-activated Cl (-) currents and contractility of smooth muscle in rat mesenteric small arteries. Pflügers Archiv - European Journal of Physiology, 466(7), 1391-1409. http://www.ncbi.nlm.nih.gov/pubmed/24162234

Dai, Y., Idorn, M., Serrero, M. C., Pan, X., Thomsen, E. A., Narita, R., Maimaitili, M., Qian, X., Iversen, M. B., Reinert, L. S., Flygaard, R. K., Chen, M., Ding, X., Zhang, B. C., Carter-Timofte, M. E., Lu, Q., Jiang, Z., Zhong, Y., Zhang, S. ... Paludan, S. R. (2024). TMEFF1 is a neuron-specific restriction factor for herpes simplex virus. Nature, 632(8024), 383-389. https://doi.org/10.1038/s41586-024-07670-z

Offersen, R., Melchjorsen, J., Paludan, S. R., Østergaard, L. J., Tolstrup, M. & Søgaard, O. S. (2012). TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults. Human Vaccines & Immunotherapeutics, 8(8), 1042-7. https://doi.org/10.4161/hv.20707

Holm, C., Petersen, C. C., Hvid, M., Petersen, L., Paludan, S. R., Deleuran, B. & Hokland, M. (2009). TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells. Journal of Immunology, 183, 4422-31. https://doi.org/10.4049/jimmunol.0804318

Reinert, L. S., Harder, L., Holm, C. K., Iversen, M. B., Horan, K. A., Dagnæs-Hansen, F., Ulhøi, B. P., Holm, T. H., Mogensen, T. H., Owens, T., Nyengaard, J. R., Thomsen, A. R. & Paludan, S. R. (2012). TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. Journal of Clinical Investigation. https://doi.org/10.1172/JCI60893

Lindner, S. C., Köhl, U., Maier, T., Steinhilber, D. & Sorg, B. L. (2009). TLR2 ligands augment cPLA2alpha activity and lead to enhanced leukotriene release in human monocytes. Journal of Leukocyte Biology, 86(2), 389-99. https://doi.org/10.1189/jlb.1008591

Sørensen, L. N., Reinert, L., Malmgaard, L., Bartholdy, C., Thomsen, A. R. & Paludan, S. R. (2008). TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain. Journal of Immunology, 181, 8604-12.

Sørensen, L. N., Reinert, L. S., Malmgaard, L., Bartholdy, C., Thomsen, A. R. & Paludan, S. R. (2008). TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain. Journal of Immunology, 181(12), 8604-12.

Reinholdt, J. & Kilian, M. (1995). Titration of inhibiting antibodies to bacterial IgA1 proteases in human sera and secretions. Advances in Experimental Medicine and Biology, 371A, 605-8.

Hanifa, M. A., Skott, M., Maltesen, R. G., Rasmussen, B. S., Nielsen, S., Frøkiær, J., Ring, T. & Wimmer, R. (2020). Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease. Data in Brief, 33, Artikel 106567. https://doi.org/10.1016/j.dib.2020.106567

Hanifa, M. A., Skott, M., Maltesen, R. G., Rasmussen, B. S., Nielsen, S., Frøkiær, J., Ring, T. & Wimmer, R. (2019). Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model. Metabolomics, 15(8), Artikel 112. https://doi.org/10.1007/s11306-019-1569-3

Pamphlett, R., Danscher, G., Rungby, J. & Stoltenberg, M. (2000). Tissue uptake of bismuth from shotgun pellets. Environmental Research, 82(3), 258-62. https://doi.org/10.1006/enrs.1999.4016

Boros, S., Xi, Q., Dimke, H. A., van der Kemp, A. W., Tudpor, K., Verkaart, S., Lee, K. P., Bindels, R. J. & Hoenderop, J. G. (2011). Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-011-0818-z

Mikkelsen, T. R., Brandt, J., Larsen, H. J., Larsen, B. B., Poulsen, K., Ingerslev, J., Din, N. & Hjorth, J. P. (1992). Tissue-specific expression in the salivary glands of transgenic mice. Nucleic Acids Research, 20(9), 2249-55.

West, M. J. (2013). Tissue shrinkage and stereological studies. Cold Spring Harbor Protocols, 2013(3). https://doi.org/10.1101/pdb.top071860

Etzerodt, A., Moulin, M., Doktor, T. K., Delfini, M., Mossadegh-Keller, N., Bajenoff, M., Sieweke, M. H., Moestrup, S. K., Auphan-Anezin, N. & Lawrence, T. (2020). Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer. The Journal of Experimental Medicine, 217(4), Artikel e20191869. https://doi.org/10.1084/jem.20191869

Goncalves, N. P., Goncalves, P., Magalhaes, J., Ventosa, M., Coelho, A. V. & Saraiva, M. J. (2016). Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model. Neurobiology of Aging, 47, 91-101. https://doi.org/10.1016/j.neurobiolaging.2016.07.020

Holmskov, U. L., Teisner, B., Pedersen, N. T., Laursen, S., Rasmussen, H. B. & Jensenius, J. C. (1992). Tissue localization of conglutinin, a bovine C-type lectin. Immunology, 76(1), 169-73.

El Moghrabi, S., Houillier, P., Picard, N., Sohet, F., Wootla, B., Bloch-Faure, M., Leviel, F., Cheval, L., Frische, S., Meneton, P., Eladari, D. & Chambrey, R. (2010). Tissue kallikrein permits early renal adaptation to potassium load. Proceedings of the National Academy of Sciences (PNAS), 107(30), 13526-31. https://doi.org/10.1073/pnas.0913070107

Kelly, M. P., Kahr, O., Aalkjær, C., Cumin, F. & Samani, N. J. (1997). Tissue expression of components of the renin-angiotensin system in experimental post-infarction heart failure in rats: effects of heart failure and angiotensin-converting enzyme inhibitor treatment. Clinical Science, 92(5), 455-465.

Grimm, D., Egli, M., Krüger, M., Riwaldt, S., Corydon, T. J., Kopp, S., Wehland, M., Wise, P., Infanger, M., Mann, V. & Sundaresan, A. (2018). Tissue Engineering Under Microgravity Conditions-Use of Stem Cells and Specialized Cells. Stem Cells and Development, 27(12), 787-804. https://doi.org/10.1089/scd.2017.0242

Wehland, M., Steinwerth, P., Aleshcheva, G., Sahana, J., Hemmersbach, R., Lützenberg, R., Kopp, S., Infanger, M. & Grimm, D. (2020). Tissue Engineering of Cartilage Using a Random Positioning Machine. International Journal of Molecular Sciences , 21(24), 1-24. Artikel 9596. https://doi.org/10.3390/ijms21249596

Aleshcheva, G., Bauer, J., Hemmersbach, R., Egli, M., Wehland, M. & Grimm, D. (2016). Tissue Engineering of Cartilage on Ground-Based Facilities. Microgravity - Science and Technology, 28(3), 237-245. Artikel 10.1007/s12217-015-9479-0. https://doi.org/10.1007/s12217-015-9479-0

Grimm, D., Buken, C., Sahana, J., Bauer, J., Wehland, M., Warnke, E., Kopp, S., Krueger, M., Riwaldt, S., Hemmersbach, R., Corydon, T. J. & Infanger, M. (2018). Tissue engineering and microgravity. Proceedings of the International Astronautical Congress, IAC, 2018-October.

Røpcke, D. M., Rasmussen, J., Ilkjær, C., Skov, S. N., Tjørnild, M. J., Baandrup, U., Danielsen, C. C. & Nielsen, S. L. (2016). Tissue engineered tricuspid valve tube graft: Histology and biomechanics. Poster-session præsenteret på 2nd Annual Meeting, Heart Valve Society, New York, USA.

Basse, P., Herberman, R. B., Hokland, M. & Goldfarb, R. H. (1992). Tissue distribution of adoptively transferred adherent lymphokine-activated killer cells assessed by different cell labels. Cancer Immunology, Immunotherapy, 34(4), 221-7.

Bentzon, J. F., Stenderup, K., Dagnæs-Hansen, F., Abdallah, B. M., Schrøder, H. D., Jensen, T. G. & Kassem, M. (2005). Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene. Biochem. Biophys. Res. Commun., 330, 633-640.

Bentzon, J. F., Stenderup, K., Hansen, F. D., Schroder, H. D., Abdallah, B., Jensen, T. G. & Kassem, M. (2005). Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene. Biochemical and Biophysical Research Communications, 330(3), 633-40. https://doi.org/10.1016/j.bbrc.2005.03.072

Duarte-Silva, E., Oriá, A. C., Mendonça, I. P., de Melo, M. G., Paiva, I. H. R., Maes, M., Joca, S. R. L. & Peixoto, C. A. (2022). Tiny in size, big in impact: Extracellular vesicles as modulators of mood, anxiety and neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews, 135, Artikel 104582. https://doi.org/10.1016/j.neubiorev.2022.104582

Jensen, K. M., Melchjorsen, J., Dagnaes-Hansen, F., Sørensen, U. B. S., Laursen, R. R., Østergaard, L. J., Søgaard, O. S. & Tolstrup, M. (2012). Timing of Toll-like receptor 9 agonist administration in pneumococcal vaccination impacts both humoral and cellular immune responses as well as nasopharyngeal colonization in mice. Microcosm - I I I, 80(5), 1744-52. https://doi.org/10.1128/IAI.00079-12

Nielsen, S. Y., Hoffmann-Lücke, E., Henriksen, T. B., Hartvigsen, C. M., Helmig, R. B., Khalil, M. R., Møller, J. K., Pedersen, L. H., Murra, M. & Greibe, E. (2025). Timing and dosage of intrapartum prophylactic penicillin for preventing early-onset group B streptococcal disease: Assessing maternal and umbilical cord blood concentration. Archives of Disease in Childhood: Fetal and Neonatal Edition, 110(2), F128-F132. Artikel fetalneonatal-2024-326986. https://doi.org/10.1136/archdischild-2024-326986

Gong, J. Y., Morton, J. I., Chen, L., Sacre, J. W., Carstensen, B., Gregg, E. W., Pavkov, M. E., Arffman, M., Booth, G. L., Ter Braake, J. G., Chu, L. M., Fleetwood, K., Fosse-Edorh, S., Garbuviene, M., Guion, M., Ha, K. H., Kaul, P., Ke, C., Keskimäki, I. ... Magliano, D. J. (2026). Time trends in mortality from heart failure and atherosclerotic cardiovascular disease in people with and without diabetes: a multi-national population-based study. The lancet. Diabetes & endocrinology, 14(1), 20-28. https://doi.org/10.1016/S2213-8587(25)00265-7

Dale, G. H., Petersen, T., Svendsen, K. B., Christensen, T., Houen, G. & Bek, T. (2018). Time to steroid treatment in severe acute optic neuritis. Brain and Behavior, 8(8), Artikel e01032. https://doi.org/10.1002/brb3.1032

Troldborg, A., Thomsen, M. K., Bartels, L. E., Andersen, J. B., Vils, S. R., Mistegaard, C. E., Johannsen, A. D., Hermansen, M.-L. F., Mikkelsen, S., Erikstrup, C., Hauge, E.-M. & Ammitzbøll, C. (2022). Time since rituximab treatment is essential for developing a humoral response to COVID-19 mRNA vaccines in patients with rheumatic diseases. The Journal of Rheumatology, 49(6), 644-649. https://doi.org/10.3899/jrheum.211152

Skipper, K. A., Nielsen, M. G., Andersen, S., Ryø, L. B., Bak, R. O. & Mikkelsen, J. G. (2018). Time-Restricted PiggyBac DNA Transposition by Transposase Protein Delivery Using Lentivirus-Derived Nanoparticles. Molecular Therapy - Nucleic Acids, 11, 253-262. https://doi.org/10.1016/j.omtn.2018.02.006

Røhl, L., Sakoh, M., Simonsen, C. Z., Vestergaard-Poulsen, P., Sangill, R., Sørensen, J. C. H., Bjarkam, C., Gyldensted, C. & Østergaard, L. (2002). Time evolution of cerebral perfusion and apparent diffusion coefficient measured by magnetic resonance imaging in a porcine stroke model. Journal of Magnetic Resonance Imaging, 15(2), 123-9. https://doi.org/10.1002/jmri.10068

Le Douarin, B., You, J., Nielsen, A. L., Chambon, P. & Losson, R. (1998). TIF1alpha: a possible link between KRAB zinc finger proteins and nuclear receptors. Journal of Steroid Biochemistry and Molecular Biology, 65(1-6), 43-50.

Eika, B., Mølgaard, H., Sonne, O. & Jørgensen, J. O. L. (2001). Tidlig klinik - en øjeblikkelig succes. Beskrivelse af en ny studieordning på Aarhus Universitet. Ugeskrift for Læger, 163, 3626-3629.

Riis, A. L. D., Hansen, T. K., Thiel, S., Gravholt, C. H., Gjedde, S., Gormsen, L. C., Jørgensen, J. O. L., Weeke, J. & Møller, N. (2005). Thyroid hormone increases mannan-binding lectin levels. European Journal of Endocrinology, 153(5), 643-9. https://doi.org/10.1530/eje.1.02013

Warnke, E., Kopp, S., Wehland, M., Hemmersbach, R., Bauer, J., Pietsch, J., Infanger, M. & Grimm, D. (2016). Thyroid Cells Exposed to Simulated Microgravity Conditions – Comparison of the Fast Rotating Clinostat and the Random Positioning Machine. Microgravity - Science and Technology, 28(3), 247-260. https://doi.org/10.1007/s12217-015-9456-7

Kopp, S., Krüger, M., Feldmann, S., Oltmann, H., Schütte, A., Schmitz, B., Bauer, J., Schulz, H., Saar, K., Huebner, N., Wehland, M., Nassef, M. Z., Melnik, D., Meltendorf, S., Infanger, M. & Grimm, D. (2018). Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project. Scientific Reports, 8(1), Artikel 10355. https://doi.org/10.1038/s41598-018-28695-1

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Revideret 21.08.2025