Peer-reviewed publikationer

Peer-reviewed publications

Borchard, S., Raschke, S., Zak, K. M., Eberhagen, C., Einer, C., Weber, E., Müller, S. M., Michalke, B., Lichtmannegger, J., Wieser, A., Rieder, T., Popowicz, G. M., Adamski, J., Klingenspor, M., Coles, A. H., Viana, R., Vendelbo, M. H., Sandahl, T. D., Schwerdtle, T. ... Zischka, H. (2021). Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage. Life Science Alliance, 5(3), Artikel e202101164. https://doi.org/10.26508/lsa.202101164

Łuczkowska, K., Sokolowska, K. E., Taryma-Lesniak, O., Pastuszak, K., Supernat, A., Bybjerg-Grauholm, J., Hansen, L. L., Paczkowska, E., Wojdacz, T. K. & Machaliński, B. (2021). Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound. Scientific Reports, 11(1), Artikel 9846. https://doi.org/10.1038/s41598-021-89128-0

Grubb, S., Lauritzen, M. & Aalkjær, C. (2021). Brain capillary pericytes and neurovascular coupling. Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, 254, Artikel 110893. https://doi.org/10.1016/j.cbpa.2020.110893

Reinert, L. S., Rashidi, A. S., Tran, D. N., Katzilieris-Petras, G., Hvidt, A. K., Gohr, M., Fruhwürth, S., Bodda, C., Thomsen, M. K., Vendelbo, M. H., Khan, A. R., Hansen, B., Bergström, P., Agholme, L., Mogensen, T. H., Christensen, M. H., Nyengaard, J. R., Sen, G. C., Zetterberg, H. ... Paludan, S. R. (2021). Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production. Journal of Clinical Investigation, 131(1), Artikel e136824. https://doi.org/10.1172/JCI136824

Klose-Jensen, R., Hartlev, L. B., Thomsen, J. S., Nyengaard, J. R., Boel, L. W. T., Laursen, M., Laurberg, T. B., Stengaard-Pedersen, K. & Hauge, E. M. (2021). Calcified cartilage in patients with osteoarthritis of the hip compared to that of healthy subjects. A design-based histological study. Bone, 143, Artikel 115660. https://doi.org/10.1016/j.bone.2020.115660

Stewart, L. M., Gerner, L., Rettel, M., Stein, F., Burrows, J. F., Mills, I. G. & Evergren, E. (2021). CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. Cell Death and Disease, 12(11), Artikel 1040. https://doi.org/10.1038/s41419-021-04335-x

Breining, P., Frølund, A. L., Højen, J. F., Gunst, J. D., Staerke, N. B., Sædder, E. A., Cases-Thomas, M., Little, P., Nielsen, L. P., Søgaard, O. S. & Kjolby, M. (2021). Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety. Basic & Clinical Pharmacology & Toxicology, 128(2), 204-212. https://doi.org/10.1111/bcpt.13533

Hoffmann, M., Hofmann-Winkler, H., Smith, J. C., Krüger, N., Arora, P., Sørensen, L. K., Søgaard, O. S., Hasselstrøm, J. B., Winkler, M., Hempel, T., Raich, L., Olsson, S., Danov, O., Jonigk, D., Yamazoe, T., Yamatsuta, K., Mizuno, H., Ludwig, S., Noé, F. ... Pöhlmann, S. (2021). Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65, Artikel 103255. https://doi.org/10.1016/j.ebiom.2021.103255

Pedrazzi, J. F. C., Sales, A. J., Guimarães, F. S., Joca, S. R. L., Crippa, J. A. S. & Del Bel, E. (2021). Cannabidiol prevents disruptions in sensorimotor gating induced by psychotomimetic drugs that last for 24-h with probable involvement of epigenetic changes in the ventral striatum. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 111, Artikel 110352. https://doi.org/10.1016/j.pnpbp.2021.110352

Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K. L., Horsted, E. W., Erdoğan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M. ... Sander, A. F. (2021). Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity. Nature Communications, 12(1), Artikel 324. https://doi.org/10.1038/s41467-020-20251-8

Sanchez-Solares, J., Sanchez, L., Pablo-Torres, C., Diaz-Fernandez, C., Sørensen, P., Barber, D. & Gomez-Casado, C. (2021). Celiac Disease Causes Epithelial Disruption and Regulatory T Cell Recruitment in the Oral Mucosa. Frontiers in Immunology, 12, Artikel 623805. https://doi.org/10.3389/fimmu.2021.623805

Grimm, D. G. (2021). Cell and Molecular Biology of Thyroid Disorders 2.0. International Journal of Molecular Medicine, 22(4), 1-7. Artikel 1990. https://doi.org/10.3390/ijms22041990

Pedersen, J. G., Egedal, J. H., Packard, T. A., Thavachelvam, K., Xie, G., van der Sluis, R. M., Greene, W. C., Roan, N. R. & Jakobsen, M. R. (2021). Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status. Frontiers in Microbiology, 12, Artikel 763030. https://doi.org/10.3389/fmicb.2021.763030

Blay-Cadanet, J., Pedersen, A. & Holm, C. K. (2021). Cellular Metabolites Regulate Central Nucleic Acid Sensing Pathways. Frontiers in Immunology, 12, Artikel 635738. https://doi.org/10.3389/fimmu.2021.635738

Raaby Gammelgaard, K., Sandfeld-Paulsen, B., Godsk, S. H., Demuth, C., Meldgaard, P., Sorensen, B. S. & Jakobsen, M. R. (2021). cGAS-STING pathway expression as a prognostic tool in NSCLC. Translational Lung Cancer Research, 10(1), 340-354. https://doi.org/10.21037/tlcr-20-524

Haslund-Krog, S. S., Jorgensen, I. M., Henriksen, T. B., Dalhoff, K., Debes, N. M., van den Anker, J. & Holst, H. (2021). Challenges in conducting paediatric trials with off-patent drugs. Contemporary Clinical Trials Communications, 23, Artikel 100783. https://doi.org/10.1016/j.conctc.2021.100783

Wise, P. M., Neviani, P., Riwaldt, S., Corydon, T. J., Wehland, M., Braun, M., Krüger, M., Infanger, M. & Grimm, D. (2021). Changes in exosomal mirna composition in thyroid cancer cells after prolonged exposure to real microgravity in space. International Journal of Molecular Sciences , 22(23), Artikel 12841. https://doi.org/10.3390/ijms222312841

Wise, P. M., Neviani, P., Riwaldt, S., Corydon, T. J., Wehland, M., Braun, M., Krüger, M., Infanger, M. & Grimm, D. (2021). Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space. International Journal of Molecular Sciences , 22(4), Artikel 2132. https://doi.org/10.3390/ijms22042132

Fredslund, S. O., Buus, N. H., Skjold, C., Laugesen, E., Jensen, A. B. & Laursen, B. E. (2021). Changes in vascular function during breast cancer treatment. British Journal of Clinical Pharmacology, 87(11), 4230-4240. https://doi.org/10.1111/bcp.14837

Moldovan, L. I., Tsoi, L. C., Ranjitha, U., Hager, H., Weidinger, S., Gudjonsson, J. E., Kjems, J. & Kristensen, L. S. (2021). Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles. Experimental Dermatology, 30(8), 1187-1196. https://doi.org/10.1111/exd.14227

Juul-Madsen, K., Troldborg, A., Wittenborn, T. R., Axelsen, M. G., Zhao, H., Klausen, L. H., Luecke, S., Paludan, S. R., Stengaard-Pedersen, K., Dong, M., Møller, H. J., Thiel, S., Jensen, H., Schuck, P., Sutherland, D. S., Degn, S. E. & Vorup-Jensen, T. (2021). Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus. Proceedings of the National Academy of Sciences (PNAS), 118(30), Artikel e2106647118. https://doi.org/10.1073/pnas.2106647118

Greisen, S. R. & Deleuran, B. (2021). Checkpoint Molecules in Rheumatology—or the Benefits of Being Exhausted. Current Rheumatology Reports, 23(4), Artikel 22. https://doi.org/10.1007/s11926-021-00991-2

Pedersen, T. H., Macdonald, W. A., Broch-Lips, M., Halldorsdottir, O. & Bækgaard Nielsen, O. (2021). Chloride channel inhibition improves neuromuscular function under conditions mimicking neuromuscular disorders. Acta Physiologica, 233(2), Artikel e13690. https://doi.org/10.1111/apha.13690

Kravtsova, V. V., Paramonova, I. I., Vilchinskaya, N. A., Tishkova, M. V., Matchkov, V. V., Shenkman, B. S. & Krivoi, I. I. (2021). Chronic ouabain prevents na,k-atpase dysfunction and targets ampk and il-6 in disused rat soleus muscle. International Journal of Molecular Sciences , 22(8), Artikel 3920. https://doi.org/10.3390/ijms22083920

Olesen, M. T. J. & Kristensen, L. S. (2021). Circular RNAs as microRNA sponges: Evidence and controversies. Essays in Biochemistry, 65(4), 685-696. https://doi.org/10.1042/EBC20200060

Damgaard, C., Danielsen, A. K., Enevold, C., Reinholdt, J., Holmstrup, P., Nielsen, C. H. & Massarenti, L. (2021). Circulating antibodies against leukotoxin A as marker of periodontitis Grades B and C and oral infection with Aggregatibacter actinomycetemcomitans. Journal of Periodontology, 92(12), 1795-1804. https://doi.org/10.1002/JPER.20-0895

Uriarte, M., De Francesco, P. N., Fernández, G., Castrogiovanni, D., D'Arcangelo, M., Imbernon, M., Cantel, S., Denoyelle, S., Fehrentz, J. A., Praetorius, J., Prevot, V. & Perello, M. (2021). Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms. Molecular and Cellular Endocrinology, 538, Artikel 111449. https://doi.org/10.1016/j.mce.2021.111449

Doherty, M. A., Langdahl, B. L., Vogel Denmark, I. & Haagerup, A. (2021). Clinical and genetic evaluation of Danish patients with pycnodysostosis. European Journal of Medical Genetics, 64(2), 104135. Artikel 104135. https://doi.org/10.1016/j.ejmg.2021.104135

Sagerfors, S., Poehlein, A., Afshar, M., Lindblad, B. E., Brüggemann, H. & Söderquist, B. (2021). Clinical and genomic features of Corynebacterium macginleyi-associated infectious keratitis. Scientific Reports, 11(1), 6015. Artikel 6015. https://doi.org/10.1038/s41598-021-85336-w

Nielsen, M. L., Lildballe, D. L., Rasmussen, M., Bojesen, A., Birn, H. & Sunde, L. (2021). Clinical genetic diagnostics in Danish autosomal dominant polycystic kidney disease patients reveal possible founder variants. European Journal of Medical Genetics, 64(4), Artikel 104183. https://doi.org/10.1016/j.ejmg.2021.104183

Sartim, A. G., Marques, J., Silveira, K. M., Gobira, P. H., Guimarães, F. S., Wegener, G. & Joca, S. R. (2021). Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects. Neuropharmacology, 195, Artikel 108679. https://doi.org/10.1016/j.neuropharm.2021.108679

Laursen, I. H., Banasik, K., Haue, A. D., Petersen, O., Holm, P. C., Westergaard, D., Bundgaard, H., Brunak, S., Frikke-Schmidt, R., Holm, H., Sørensen, E., Thørner, L. W., Larsen, M. A. H., Schwinn, M., Køber, L., Torp-Pedersen, C., Ostrowski, S. R., Erikstrup, C., Nyegaard, M. ... Ullum, H. (2021). Cohort profile: Copenhagen Hospital Biobank - Cardiovascular Disease Cohort (CHB-CVDC): Construction of a large-scale genetic cohort to facilitate a better understanding of heart diseases. BMJ Open, 11(12), Artikel e049709. https://doi.org/10.1136/bmjopen-2021-049709

Vandewalle, J., Timmermans, S., Paakinaho, V., Vancraeynest, L., Dewyse, L., Vanderhaeghen, T., Wallaeys, C., Van Wyngene, L., Van Looveren, K., Nuyttens, L., Eggermont, M., Dewaele, S., Velho, T. R., Moita, L. F., Weis, S., Sponholz, C., van Grunsven, L. A., Dewerchin, M., Carmeliet, P. ... Libert, C. (2021). Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis. Cell Metabolism, 33(9), 1763-1776.e5. https://doi.org/10.1016/j.cmet.2021.07.002

Schubert, K. O., Thalamuthu, A., Amare, A. T., Frank, J., Streit, F., Adl, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J.-M., Backlund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Marie-Claire, C. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry, 11(1), Artikel 606. https://doi.org/10.1038/s41398-021-01702-2

Zhao, B., Li, T., Yang, Y., Wang, X., Luo, T., Shan, Y., Zhu, Z., Xiong, D., Hauberg, M. E., Bendl, J., Fullard, J. F., Roussos, P., Li, Y., Stein, J. L. & Zhu, H. (2021). Common genetic variation influencing human white matter microstructure. Science, 372(6548), Artikel eabf3736. https://doi.org/10.1126/science.abf3736

Banerjee, S., Zhang, X., Kuang, S., Wang, J., Li, L., Fan, G., Luo, Y., Sun, S., Han, P., Wu, Q., Yang, S., Ji, X., Li, Y., Deng, L., Tian, X., Wang, Z., Zhang, Y., Wu, K., Zhu, S. ... Liu, X. (2021). Comparative analysis of clonal evolution among patients with right- and left-sided colon and rectal cancer. iScience, 24(7), Artikel 102718. https://doi.org/10.1016/j.isci.2021.102718

Berthelsen, M. F., Leknes, S. L., Riedel, M., Pedersen, M. A., Joseph, J. V., Hager, H., Vendelbo, M. H. & Thomsen, M. K. (2021). Comparative analysis of Stk11/Lkb1 versus Pten deficiency in lung adenocarcinoma induced by CRISPR/Cas9. Cancers, 13(5), Artikel 974. https://doi.org/10.3390/cancers13050974

Blijdorp, C. J., Tutakhel, O. A. Z., Hartjes, T. A., van den Bosch, T. P. P., van Heugten, M. H., Rigalli, J. P., Willemsen, R., Musterd-Bhaggoe, U. M., Barros, E. R., Carles-Fontana, R., Carvajal, C. A., Arntz, O. J., van de Loo, F. A. J., Jenster, G., Clahsen-van Groningen, M. C., Cuevas, C. A., Severs, D., Fenton, R. A., van Royen, M. E. ... Hoorn, E. J. (2021). Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles. Journal of the American Society of Nephrology : JASN, 32(5), 1210-1226. https://doi.org/10.1681/ASN.2020081142

Wittenborn, T. R., Hagert, C. F., Ferapontov, A., Fonager, S., Jensen, L., Winther, G. & Degn, S. E. (2021). Comparison of gamma and x-ray irradiation for myeloablation and establishment of normal and autoimmune syngeneic bone marrow chimeras. PLoS One, 16(3), Artikel e0247501. https://doi.org/10.1371/journal.pone.0247501

Vestergaard, S. V., Birn, H., Hansen, A. T., Nørgaard, M., Nitsch, D. & Christiansen, C. F. (2021). Comparison of Patients with Hospital-recorded Nephrotic Syndrome and Patients with Nephrotic Proteinuria and Hypoalbuminemia: a Nationwide Study in Denmark. Kidney360, 2(9), 1482-1490. https://doi.org/10.34067/KID.0000362021

Ahle, C. M., Stødkilde-Jørgensen, K., Poehlein, A., Streit, W. R., Hüpeden, J. & Brüggemann, H. (2021). Comparison of three amplicon sequencing approaches to determine staphylococcal populations on human skin. BMC Microbiology, 21(1), Artikel 221. https://doi.org/10.1186/s12866-021-02284-1

Jensen, R. K., Bajic, G., Sen, M., Springer, T. A., Vorup-Jensen, T. & Andersen, G. R. (2021). Complement receptor 3 forms a compact high-affinity complex with iC3b. Journal of Immunology, 206(12), 3032-3042. https://doi.org/10.4049/jimmunol.2001208

Sagerfors, S., Poehlein, A., Söderquist, B. & Brüggemann, H. (2021). Complete genome sequences of two Corynebacterium macginleyi strains isolated from infectious keratitis. Microbiology Resource Announcements, 10(17), Artikel e00207-21. https://doi.org/10.1128/MRA.00207-21

Afshar, M., Poehlein, A., Söderquist, B. & Brüggemann, H. (2021). Complete Genome Sequences of Two Staphylococcus saccharolyticus Strains Isolated from Prosthetic Joint Infections. Microbiology Resource Announcements, 10(10), Artikel e00157-21. https://doi.org/10.1128/MRA.00157-21

Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M. F., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W. ... Sakamoto, K. (2021). Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle. Molecular Metabolism, 51, Artikel 101228. https://doi.org/10.1016/j.molmet.2021.101228

Rindom, E., Herskind, J., Blaauw, B., Overgaard, K., Vissing, K. & de Paoli, F. V. (2021). Concomitant excitation and tension development are required for myocellular gene expression and protein synthesis in rat skeletal muscle. Acta Physiologica, 231(1), Artikel e13540. https://doi.org/10.1111/apha.13540

Byrne, E. M., Zhu, Z., Qi, T., Skene, N. G., Bryois, J., Pardinas, A. F., Stahl, E., Smoller, J. W., Rietschel, M., Owen, M. J., Walters, J. T. R., O'Donovan, M. C., McGrath, J. G., Hjerling-Leffler, J., Sullivan, P. F., Goddard, M. E., Visscher, P. M., Yang, J., Wray, N. R. & Bipolar Working Group of the Psychiatric Genomics Consortium (2021). Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry, 26(6), 2070-2081. https://doi.org/10.1038/s41380-020-0705-9

Paludan, S. R. & Mogensen, T. H. (2021). Constitutive and latent immune mechanisms exert ‘silent’ control of virus infections in the central nervous system. Current Opinion in Immunology, 72, 158-166. https://doi.org/10.1016/j.coi.2021.05.004

Paludan, S. R., Pradeu, T., Masters, S. L. & Mogensen, T. H. (2021). Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature Reviews Immunology, 21(3), 137-150. https://doi.org/10.1038/s41577-020-0391-5

Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T. M., Melbye, M., Hougaard, D. M. & Christiansen, M. (2021). Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study. Journal of Neurodevelopmental Disorders, 13(1), 19. Artikel 19. https://doi.org/10.1186/s11689-021-09367-0

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