Peer-reviewed publikationer

Peer-reviewed publications

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Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019). Investigating the association between body fat and depression via Mendelian randomization. Translational Psychiatry, 9(1), artikel 184. https://doi.org/10.1038/s41398-019-0516-4

Speed, D., Hemani, G., Speed, M. S., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Børglum, A. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica, 139(4), 395-397. https://doi.org/10.1111/acps.13009

Staehr, C., Rajanathan, R. & Matchkov, V. V. (2019). Involvement of the Na ⁺ ,K ⁺-ATPase isoforms in control of cerebral perfusion. Experimental Physiology, 104(7), 1023-1028. https://doi.org/10.1113/EP087519

Mogensen, T. H. (2019). IRF and STAT transcription factors - From basic biology to roles in infection, protective immunity, and primary immunodeficiencies. Frontiers in Immunology, 9, artikel 3047. https://doi.org/10.3389/fimmu.2018.03047

Alstrup, T., Eijken, M., Bohn, A. B., Møller, B. & Damsgaard, T. E. (2019). Isolation of Adipose Tissue-Derived Stem Cells: Enzymatic Digestion in Combination with Mechanical Distortion to Increase Adipose Tissue-Derived Stem Cell Yield from Human Aspirated Fat. Current protocols in stem cell biology, 48(1), artikel e68. adv. onlinepublikation. https://doi.org/10.1002/cpsc.68

Poulsen, S. B. & Fenton, R. A. (2019). K+ and the renin-angiotensin-aldosterone system: new insights into their role in blood pressure control and hypertension treatment. The Journal of Physiology, 597(17), 4451-4464. adv. onlinepublikation. https://doi.org/10.1113/JP276844

Fredslund, S. O., Gravholt, C. H., Laursen, B. E. & Jensen, A. B. (2019). Key metabolic parameters change significantly in early breast cancer survivors: An explorative PILOT study. Journal of Translational Medicine, 17(1), artikel 105. https://doi.org/10.1186/s12967-019-1850-2

King, D., Glynn, M. D., Cindric, S., Kernan, D., O’Connell, T., Hakimjavadi, R., Kearney, S., Ackermann, T., Berbel, X. M., Llobera, A., Simonsen, U., Laursen, B. E., Redmond, E. M., Cahill, P. A. & Ducrée, J. (2019). Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform. Scientific Reports, 9, artikel 4157. https://doi.org/10.1038/s41598-019-40612-8

Therkildsen, J. R., Christensen, M. G., Tingskov, S. J., Wehmöller, J., Nørregaard, R. & Praetorius, H. A. (2019). Lack of P2X ₇ Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin–Producing Escherichia coli. American Journal of Pathology, 189(6), 1201-1211. https://doi.org/10.1016/j.ajpath.2019.02.013

Larsen, J. B., Andersen, A. S., Hvas, C. L., Thiel, S., Lassen, M. R., Hvas, A-M. & Hansen, A. T. (2019). Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia. American Journal of Reproductive Immunology Online, 81(4), e13092. artikel e13092. https://doi.org/10.1111/aji.13092

M'kacher, R., Junker, S., Jeandidier, E. & Carde, P. (2019). Letter to the editor of environmental and molecular mutagenesis: In regard to Ramos et al. Environmental and Molecular Mutagenesis, 60(4), 385-386. https://doi.org/10.1002/em.22282

Xiang, X., Luo, L., Nodzyński, M., Li, C., Han, P., Dou, H., Petersen, T. S., Liang, X., Pan, X., Qu, K., Yang, L., Dang, Y., Liu, X., Bolund, L., Zhang, X., Tong, G., Xing, Y., Luo, Y. & Lin, L. (2019). LION: a simple and rapid method to achieve CRISPR gene editing. Cellular and Molecular Life Sciences, 76(13), 2633-2645. https://doi.org/10.1007/s00018-019-03064-x

Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019). Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy, 27(8), 1424-1435. https://doi.org/10.1016/j.ymthe.2019.05.002

Andersen, M. A., Sotty, F., Jensen, P. H., Badolo, L., Jeggo, R., Smith, G. P. & Christensen, K. V. (2019). Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications. eNeuro , 6(6), artikel ENEURO.0453-18.2019. https://doi.org/10.1523/ENEURO.0453-18.2019

Pedersen, J. N., Jiang, Z., Christiansen, G., Lee, J. C., Pedersen, J. S. & Otzen, D. E. (2019). Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures. Biochimica et Biophysica Acta - Proteins and Proteomics, 1867(5), 519-528. https://doi.org/10.1016/j.bbapap.2018.11.007

Freese, N. H., Estrada, A. R., Blakley, I. C., Duan, J. & Loraine, A. E. (2019). Many rice genes are differentially spliced between roots and shoots but cytokinin has minimal effect on splicing. Plant Direct, 3(5), artikel e00136. https://doi.org/10.1002/pld3.136

Scavenius, C., Poulsen, E. C., Thøgersen, I. B., Roebuck, M., Frostick, S., Bou-Gharios, G., Yamamoto, K., Deleuran, B. & Enghild, J. J. (2019). Matrix-degrading protease ADAMTS-5 cleaves inter-αinhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients. Journal of Biological Chemistry, 294(42), 15495-15504. https://doi.org/10.1074/jbc.RA119.008844

Mohammad-Beigi, H., Hosseini, A., Adeli, M., Ejtehadi, M. R., Christiansen, G., Sahin, C., Tu, Z., Tavakol, M., Dilmaghani-Marand, A., Nabipour, I., Farzadfar, F., Otzen, D. E., Mahmoudi, M. & Hajipour, M. J. (2019). Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein. ACS Nano, 13(3), 3243-3256. https://doi.org/10.1021/acsnano.8b08983

Goossens, P., Rodriguez-Vita, J., Etzerodt, A., Masse, M., Rastoin, O., Gouirand, V., Ulas, T., Papantonopoulou, O., Van Eck, M., Auphan-Anezin, N., Bebien, M., Verthuy, C., Vu Manh, T. P., Turner, M., Dalod, M., Schultze, J. L. & Lawrence, T. (2019). Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression. Cell Metabolism, 29(6), 1376-1389.e4. adv. onlinepublikation. https://doi.org/10.1016/j.cmet.2019.02.016

Gormsen, L. C., Søndergaard, E., Christensen, N. L., Brøsen, K., Jessen, N. & Nielsen, S. (2019). Metformin increases endogenous glucose production in non-diabeticindividuals and individuals with recent-onset type 2 diabetes. Diabetologia, 62, 1251–1256. adv. onlinepublikation. https://doi.org/10.1007/s00125-019-4872-7

Myhre, C. L., Thygesen, C., Villadsen, B., Vollerup, J., Ilkjaer, L., Krohn, K. T., Grebing, M., Zhao, S., Khan, A. M., Dissing-Olesen, L., Jensen, M. S., Babcock, A. A. & Finsen, B. (2019). Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice. Frontiers in Cellular Neuroscience, 13, artikel 308. https://doi.org/10.3389/fncel.2019.00308

Due, H., Schönherz, A. A., Ryø, L., Primo, M. N., Jespersen, D. S., Thomsen, E. A., Roug, A. S., Xiao, M., Tan, X., Pang, Y., Young, K. H., Bøgsted, M., Mikkelsen, J. G. & Dybkær, K. (2019). MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma. Blood Advances, 3(7), 1185-1196. https://doi.org/10.1182/bloodadvances.2018029660

Bouzinova, E., Lykke-Hartmann, K., Nyengaard, J. R., Beck, H. C., Matchkov, V. & Staehr, C. (2019). Migraine-associated mutation in the a2 isoform Na,K-ATPase is associated with cardiomyopathy-like changes in the mouse heart. Acta Physiologica (Print), 227(S721).

Kogelman, L. J. A., Esserlind, A-L., Francke Christensen, A., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Folkmann Hansen, T. & DBDS Genomic Consortium, The International Headache Genetics Consortium (2019). Migraine polygenic risk score associates with efficacy of migraine-specific drugs. Neurology: Genetics, 5(6), artikel e364. https://doi.org/10.1212/NXG.0000000000000364

Riis, S., Christensen, B., Sørensen, B., Møller, A. B., Husted, A. S., Pedersen, S. B., Schwartz, T. W., Jørgensen, J. O. L. & Jessen, N. (2019). Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males. Journal of applied physiology (Bethesda, Md. : 1985), 126(3), 569-577. https://doi.org/10.1152/japplphysiol.00989.2018

Møller, A. B., Lønbro, S., Farup, J., Voss, T. S., Rittig, N., Wang, J., Højris, I., Mikkelsen, U. R. & Jessen, N. (2019). Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy. Journal of Cancer Research and Clinical Oncology, 145(6), 1449-1460. adv. onlinepublikation. https://doi.org/10.1007/s00432-019-02911-5

Buken, C., Sahana, J., Corydon, T. J., Melnik, D., Bauer, J., Wehland, M., Krüger, M., Balk, S., Abuagela, N., Infanger, M. & Grimm, D. (2019). Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity. Scientific Reports, 9(1), artikel 11882. https://doi.org/10.1038/s41598-019-48378-9

Mohanakumar, S., Telinius, N., Kelly, B., Lauridsen, H., Bødtkjer, D. M. B., Pedersen, M., de Leval, M. & Hjortdal, V. E. (2019). Morphology and Function of the Lymphatic Vasculature in Patients With a Fontan Circulation. Circulation: Cardiovascular Imaging, 12(4), e008074. artikel e008074. https://doi.org/10.1161/CIRCIMAGING.118.008074

Zhang, P., Gu, L., Cong, J., Zhang, J., Thomsen, J. S., Andreasen, A., Chang, S-J., Deng, S-Q., Xing, J. & Zhai, X-Y. (2019). Morphology of the initial nephron-collecting duct connection in mice using computerized 3D tracing and electron microscopy. Biochemical and Biophysical Research Communications, 509(1), 114-118. https://doi.org/10.1016/j.bbrc.2018.12.079

DellaValle, B., Hasseldam, H., Johansen, F. F., Iversen, H. K., Rungby, J. & Hempel, C. (2019). Multiple Soluble Components of the Glycocalyx Are Increased in Patient Plasma After Ischemic Stroke. Stroke, 50(10), 2948-2951. https://doi.org/10.1161/STROKEAHA.119.025953

Witt, A. H., Søgaard Kristensen, R., Fuglsang-Frederiksen, A., Pedersen, T. H., Finnerup, N. B., Kasch, H. & Tankisi, H. (2019). Muscle velocity recovery cycles in neurogenic muscles. Clinical Neurophysiology, 130(9), 1520-1527. https://doi.org/10.1016/j.clinph.2019.05.030

Migliorini, L. B., Brüggemann, H., de Sales, R. O., Koga, P. C. M., de Souza, A. V., Martino, M. D. V., Galhardo, R. S. & Severino, P. (2019). Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin: Genotypic and Phenotypic Differences Between the Pseudomonas aeruginosa Strain PA14 and Clinical Isolates. Frontiers in Microbiology, 10, artikel 1553. https://doi.org/10.3389/fmicb.2019.01553

Carter-Timofte, M. E., Hansen, A. F., Christiansen, M., Paludan, S. R. & Mogensen, T. H. (2019). Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection. Genes and Immunity, 20(3), 214-223. adv. onlinepublikation. https://doi.org/10.1038/s41435-018-0027-y

Boedtkjer, E. (2019). Na⁺,HCO₃^– cotransporter NBCn1 accelerates breast carcinogenesis. Cancer and Metastasis Reviews, 38(1-2), 165-178. https://doi.org/10.1007/s10555-019-09784-7

Olawi, N., Krüger, M., Grimm, D., Infanger, M. & Wehland, M. (2019). Nebivolol in the Treatment of Arterial Hypertension. Basic & Clinical Pharmacology & Toxicology, 125(3), 189-201. adv. onlinepublikation. https://doi.org/10.1111/bcpt.13248

Bijkerk, R., Aleksinskaya, M. A., Duijs, J. M. G. J., Veth, J., Husen, B., Reiche, D., Prehn, C., Adamski, J., Rabelink, T. J., De Mey, J. G. R. & van Zonneveld, A. J. (2019). Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation. Clinical Science, 133(2), 239-252. https://doi.org/10.1042/CS20180882

Dembic, M., Andersen, H. S., Bastin, J., Doktor, T. K., Corydon, T. J., Sass, J. O., Costa, A. L., Djouadi, F. & Andresen, B. S. (2019). Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease. Molecular Genetics and Metabolism, 126(1), 64-76. https://doi.org/10.1016/j.ymgme.2018.10.004

Mey, L., Jung, M., Roos, F., Blaheta, R., Hegele, A., Kinscherf, R. & Urbschat, A. (2019). NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells. Journal of Cancer Research and Clinical Oncology, 145(6), 1405-1416. https://doi.org/10.1007/s00432-019-02901-7

Frich, C. K., Krüger, F., Walther, R., Domar, C., Andersen, A. H. F., Tvilum, A., Dagnæs-Hansen, F., Denton, P. W., Tolstrup, M., Paludan, S. R., Münch, JJ. & Zelikin, A. N. (2019). Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs. Journal of Controlled Release, 294, 298-310. https://doi.org/10.1016/j.jconrel.2018.12.016

Wittig, N. K., Birkbak, M., Bach-Gansmo, F. L., Pacureanu, A., Okkels, M. W., Brüel, A., Thomsen, J. S. & Birkedal, H. (2019). No Signature of Osteocytic Osteolysis in Cortical Bone from Lactating NMRI Mice. Calcified Tissue International, 105(3), 308-315. https://doi.org/10.1007/s00223-019-00569-2

Duszkiewicz, A. J., McNamara, C. G., Takeuchi, T. & Genzel, L. (2019). Novelty and Dopaminergic Modulation of Memory Persistence: A Tale of Two Systems. Trends in Neurosciences, 42(2), 102-114. adv. onlinepublikation. https://doi.org/10.1016/j.tins.2018.10.002

Thomas, L., Xue, J., Murali, S. K., Fenton, R. A., Rieg, J. A. D. & Rieg, T. (2019). Npt2a inhibition in chronic kidney disease. Acta Physiologica, 227. https://doi.org/10.1111/apha.13366

Gunderstofte, C., Iversen, M. B., Peri, S., Thielke, A., Balachandran, S., Holm, C. K. & Olagnier, D. (2019). Nrf2 Negatively Regulates Type I Interferon Responses and Increases Susceptibility to Herpes Genital Infection in Mice. Frontiers in Immunology, 10, artikel 2101. https://doi.org/10.3389/fimmu.2019.02101

Witt, A. H., Søgaard Kristensen, R., Fuglsang-Frederiksen, A., Pedersen, T. H., Finnerup, N. B., Kasch, H. & Tankisi, H. (2019). O-26 Muscle velocity recovery cycles in neurogenic muscles. Clinical Neurophysiology, 130(7), e30. https://doi.org/10.1016/j.clinph.2019.04.342

Eskildsen, S., Iranzo, A., Stokholm, M., Staer, K., Ostergaard, K., Eroles, M., Otto, M., Svendsen, K., Pla, A., Vilas, D., Borghammer, P., Santamaria, J., Moller, A., Gaig, C., Brooks, D., Tolosa, E., Ostergaard, L. & Pavese, N. (2019). Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder. S786-S787. Abstract fra International Congress of Parkinson's Disease and Movement Disorders, Nice, Frankrig.

Mohammad-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A., P. Schafer, N., Amiri-Nowdijeh, A., Eskandari, H., Møller, I. M., Hosseini-Mazinani, M., Christiansen, G., Ward, J. L., Morshedi, D. & Otzen, D. (2019). Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity. Journal of Biological Chemistry, 294(11), 4215-4232. https://doi.org/10.1074/jbc.RA118.005723

Keller, K. K., Thomsen, J. S., Stengaard-Pedersen, K., Therkildsen, J., Nielsen, A. W., Schiottz-Christensen, B., Svendsen, L., Graakjær, M., Petersen, P. M., Unger, B., Kjaer, G. G., Langdahl, B. & Hauge, E. M. (2019). OP0133 One-year progression of erosive disease evaluated with high-resolution peripheral quantitative computed tomography in patients with anti-citrullinated peptide antibodies and arthralgia. Annals of the Rheumatic Diseases, 78(Suppl 2), 141-142. https://doi.org/10.1136/annrheumdis-2019-eular.985

Elfarrash, S., Jensen, N. M., Ferreira, N., Betzer, C., Thevathasan, J. V., Diekmann, R., Adel, M., Omar, N. M., Boraie, M. Z., Gad, S., Ries, J., Kirik, D., Nabavi, S. & Jensen, P. H. (2019). Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathologica Communications, 7(1), artikel 213. https://doi.org/10.1186/s40478-019-0865-5

Skals, M., Greve, A. S., Fagerberg, S. K., Johnsen, N., Christensen, M. G. & Praetorius, H. A. (2019). P2X₁ receptor blockers reduce the number of circulating thrombocytes and the overall survival of urosepsis with haemolysin-producing Escherichia coli. Purinergic Signalling, 15(2), 265-276. https://doi.org/10.1007/s11302-019-09658-1

Jørgensen, C. M., Jensen, L., Christiansen, M., Bjerre, M., Jensen, J. M. B. & Thiel, S. (2019). Pattern Recognition Molecules of the Lectin Pathway-Screening of Patients with Suspected Immunodeficiency. Journal of Clinical Immunology, 39(7), 668-677. https://doi.org/10.1007/s10875-019-00675-8

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