Holmen Olofsson, G.
, Pedersen, S. R., Aehnlich, P., Svane, I. M.
, Idorn, M. & thor Straten, P. (2021).
The capacity of CD4+ Vγ9Vδ2 T cells to kill cancer cells correlates with co-expression of CD56.
Cytotherapy,
23(7), 582-589.
https://doi.org/10.1016/j.jcyt.2021.02.003
Melnik, D., Krüger, M., Schulz, H.
, Kopp, S., Wehland, M., Bauer, J., Baselet, B., Vermeesen, R., Baatout, S.
, Corydon, T. J., Infanger, M.
& Grimm, D. (2021).
The cellbox-2 mission to the international space station: Thyroid cancer cells in space.
International Journal of Molecular Sciences ,
22(16), Article 8777.
https://doi.org/10.3390/ijms22168777
Wu, A., Wolley, M. J.
, Wu, Q., Gordon, R. D.
, Fenton, R. A. & Stowasser, M. (2021).
The Cl−/HCO3− exchanger pendrin is downregulated during oral co-administration of exogenous mineralocorticoid and KCl in patients with primary aldosteronism.
Journal of Human Hypertension,
35(10), 837-848.
https://doi.org/10.1038/s41371-020-00439-7
Berthelsen, M. F., Riedel, M., Cai, H., Skaarup, S. H., Alstrup, A. K. O., Dagnæs-Hansen, F., Luo, Y., Jensen, U. B., Hager, H.
, Liu, Y., Callesen, H., Vendelbo, M. H., Jakobsen, J. E. & Thomsen, M. K. (2021).
The CRISPR/Cas9 Minipig—A Transgenic Minipig to Produce Specific Mutations in Designated Tissues.
Cancers,
13(12), Article 3024.
https://doi.org/10.3390/cancers13123024
Zhang, C., Li, C., Yang, L., Leng, L., Jovic, D., Wang, J., Fang, F., Li, G., Zhao, D., Li, X.
, Lin, L., Luo, Y., Bolund, L., Huang, J., Lin, G. & Xu, F. (2021).
The Dynamic Changes of Transcription Factors During the Development Processes of Human Biparental and Uniparental Embryos.
Frontiers in Cell and Developmental Biology,
9, Article 709498.
https://doi.org/10.3389/fcell.2021.709498
Bulik, C. M., Thornton, L. M., Parker, R., Kennedy, H., Baker, J. H., MacDermod, C., Guintivano, J., Cleland, L., Miller, A. L., Harper, L.
, Larsen, J. T., Yilmaz, Z., Grove, J., Sullivan, P. F.
, Petersen, L. V., Jordan, J., Kennedy, M. A. & Martin, N. G. (2021).
The Eating Disorders Genetics Initiative (EDGI): study protocol.
BMC Psychiatry,
21(1), Article 234.
https://doi.org/10.1186/s12888-021-03212-3
Hansen, J. S., Hansen, R. M., Petersen, T., Gustavsen, S., Oturai, A. B., Sellebjerg, F.
, Sædder, E. A., Kasch, H., Rasmussen, P. V., Finnerup, N. B. & Svendsen, K. B. (2021).
The effect of cannabis-based medicine on neuropathic pain and spasticity in patients with multiple sclerosis and spinal cord injury: Study protocol of a national multicenter double-blinded, placebo-controlled trial.
Brain sciences,
11(9), Article 1212.
https://doi.org/10.3390/brainsci11091212
Bromer, F. D., Brent, M. B., Pedersen, M., Thomsen, J. S., Brüel, A. & Foldager, C. B. (2021).
The Effect of Normobaric Intermittent Hypoxia Therapy on Bone in Normal and Disuse Osteopenic Mice.
High Altitude Medicine and Biology,
22(2), 225-234.
https://doi.org/10.1089/ham.2020.0164
Giannakopoulou, O., Lin, K., Meng, X., Su, M.-H., Kuo, P.-H., Peterson, R. E., Awasthi, S., Moscati, A., Coleman, J. R. I., Bass, N., Millwood, I. Y., Chen, Y., Chen, Z., Chen, H.-C., Lu, M.-L., Huang, M.-C., Chen, C.-H., Stahl, E. A., Loos, R. J. F. ... 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021).
The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.
JAMA Psychiatry,
78(11), 1258-1269.
https://doi.org/10.1001/jamapsychiatry.2021.2099
Hansen, R. S.
, Thuesen, K. K., Bregnhøj, A., Moldovan, L. I., Kristensen, L. S., Grek, C. L., Ghatnekar, G. S.
, Iversen, L. & Johansen, C. (2021).
The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes.
Experimental Dermatology,
30(6), 773-781.
https://doi.org/10.1111/exd.14302
Bernth Jensen, J. M., Skeldal, S., Petersen, M. S., Møller, B. K., Hoffmann, S.
, Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2021).
The human natural anti-αGal antibody targets common pathogens by broad-spectrum polyreactivity.
Immunology,
162(4), 434-451.
https://doi.org/10.1111/imm.13297
Faraj, S. E., Valsecchi, W. M., Cerf, N. T.
, Fedosova, N., Rossi, R. C. & Montes, M. R. (2021).
The interaction of Na+, K+, and phosphate with the gastric H,K-ATPase: Kinetics of E1–E2 conformational changes assessed by eosin fluorescence measurements.
B B A - Biomembranes,
1863(1), Article 183477.
https://doi.org/10.1016/j.bbamem.2020.183477
Stock, S. J., Zoega, H., Brockway, M., Mulholland, R. H., Miller, J. E., Been, J. V., Wood, R., Abok, I. I., Alshaikh, B., Ayede, A. I., Bacchini, F., Bhutta, Z. A., Brew, B. K., Brook, J., Calvert, C., Campbell-Yeo, M., Chan, D., Chirombo, J., Connor, K. L. ... iPOP Study Team (2021).
The international Perinatal Outcomes in the Pandemic (iPOP) study: Protocol.
Wellcome Open Research,
6, Article 21.
https://doi.org/10.12688/wellcomeopenres.16507.1
Berg, P., Svendsen, S. L., Sorensen, M. V., Schreiber, R., Kunzelmann, K.
& Leipziger, J. (2021).
The molecular mechanism of CFTR- and secretin-dependent renal bicarbonate excretion.
The Journal of Physiology,
599(12), 3003-3011.
https://doi.org/10.1113/JP281285
Østergaard, J. A., Jansson Sigfrids, F., Forsblom, C., Dahlström, E. H., Thorn, L. M., Harjutsalo, V., Flyvbjerg, A.
, Thiel, S., Hansen, T. K. & Groop, P.-H. (2021).
The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes.
Scientific Reports,
11(1), 8919. Article 8919.
https://doi.org/10.1038/s41598-021-88352-y
Jan, A., Gonçalves, N. P., Vaegter, C. B., Jensen, P. H. & Ferreira, N. (2021).
The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease: Update on Models and Hypotheses.
International Journal of Molecular Sciences ,
22(15), Article 8338.
https://doi.org/10.3390/ijms22158338
Abramochkin, D. V., Kuzmin, V. S.
, Matchkov, V., Kamensky, A. A.
& Wang, T. (2021).
The snake heart pacemaker is localized near the sinoatrial valve.
Journal of Experimental Biology,
224(16), Article jeb242778.
https://doi.org/10.1242/JEB.242778
Schack, V. R., Rossen, L. S., Ekebjærg, C. C., Thuesen, K. K. H., Bundgaard, B. & Höllsberg, P. B. (2021).
The Tetraspanin Protein CD9 Modulates Infection with Human Herpesvirus 6A and 6B in a CD46-Dependent Manner.
Journal of Virology,
95(8), Article e02259-20.
https://doi.org/10.1128/JVI.02259-20
Vareecal Joseph, J., Blaavand, M. S., Daubon, T., Kruyt, F. AE.
& Thomsen, M. K. (2021).
Three-dimensional culture models to study glioblastoma — current trends and future perspectives.
Current Opinion in Pharmacology,
61, 91-97.
https://doi.org/10.1016/j.coph.2021.08.019
Miles, A. E., Dos Santos, F. C., Byrne, E. M., Renteria, M. E., McIntosh, A. M., Adams, M. J., Pistis, G., Castelao, E., Preisig, M., Baune, B. T., Schubert, K. O., Lewis, C. M., Jones, L. A., Jones, I., Uher, R., Smoller, J. W., Perlis, R. H., Levinson, D. F., Potash, J. B. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021).
Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk.
Neuropsychopharmacology,
46(13), 2304-2311.
https://doi.org/10.1038/s41386-021-01189-x
Prat-Duran, J., Pinilla, E., Nørregaard, R., Simonsen, U. & Buus, N. H. (2021).
Transglutaminase 2 as a novel target in chronic kidney disease - Methods, mechanisms and pharmacological inhibition.
Pharmacology & Therapeutics,
222, Article 107787.
https://doi.org/10.1016/j.pharmthera.2020.107787
Pinilla, E., Comerma Steffensen, S. G., Prat Duran, J., Rivera, L.
, Matchkov, V., Buus, N. H. & Simonsen, U. (2021).
Transglutaminase 2 Inhibitor LDN 27219 Age-Dependently Lowers Blood Pressure and Improves Endothelium-Dependent Vasodilation in Resistance Arteries.
Hypertension,
77(1), 216-227.
https://doi.org/10.1161/HYPERTENSIONAHA.120.15352
Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M.
, Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, T., Lage, K. & Regeneron Genetics Center (2021).
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.
Nature Communications,
12(1), Article 5276.
https://doi.org/10.1038/s41467-021-25014-7
Ferreira, N., Gonçalves, N. P., Jan, A., Jensen, N. M., van der Laan, A., Mohseni, S.
, Vægter, C. B. & Jensen, P. H. (2021).
Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain.
Acta Neuropathologica Communications,
9(1), Article 31.
https://doi.org/10.1186/s40478-021-01131-8
Petersen, A. G., Lind, P. C., Jensen, A.-S. B., Eggertsen, M. A., Granfeldt, A. & Simonsen, U. (2021).
Treatment with senicapoc in a porcine model of acute respiratory distress syndrome.
Intensive Care Medicine Experimental,
9(1), Article 20.
https://doi.org/10.1186/s40635-021-00381-z
Hald, S. M., Möller, S., García Rodríguez, L. A., Salman, R. A. S., Sharma, M., Christensen, H.
, Hellfritzsch, M., Pottegård, A., Hallas, J. & Gaist, D. (2021).
Trends in Incidence of Intracerebral Hemorrhage and Association with Antithrombotic Drug Use in Denmark, 2005-2018.
JAMA network open,
4(5), Article e218380.
https://doi.org/10.1001/jamanetworkopen.2021.8380
Hatje, F., Wedekind, U., Sachs, W., Loreth, D., Reichelt, J.
, Demir, F., Kosub, C., Heintz, L., Tomas, N., Huber, T., Skuza, S., Sachs, M., Zielinski, S.
, Rinschen, M. & Meyer-Schwesinger, C. (2021).
Tripartite Separation of Glomerular Cell-Types and Proteomes From Reporter-Free Mice.
Journal of the American Society of Nephrology : JASN,
32(9), 2175-2193.
https://doi.org/10.1681/ASN.2020091346
Teuwen, L. A., De Rooij, L. P. M. H., Cuypers, A., Rohlenova, K., Dumas, S. J., García-Caballero, M., Meta, E., Amersfoort, J., Taverna, F., Becker, L. M., Veiga, N., Cantelmo, A. R., Geldhof, V., Conchinha, N. V.
, Kalucka, J., Treps, L., Conradi, L. C., Khan, S., Karakach, T. K.
... Carmeliet, P. (2021).
Tumor vessel co-option probed by single-cell analysis.
Cell Reports,
35(11), Article 109253.
https://doi.org/10.1016/j.celrep.2021.109253
Hudecz, D., Sigurdardóttir, S. B.
, Christensen, S. C., Hempel, C., Urquhart, A. J., Andresen, T. L.
& Nielsen, M. S. (2021).
Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells.
PLOS ONE,
16(4 ), Article e0249686.
https://doi.org/10.1371/journal.pone.0249686
Cong, J., Chang, S.-J.
, Thomsen, J. S., Andreasen, A., Chen, X., Xing, J., Zhang, J., Gu, L. & Zhai, X.-Y. (2021).
Ultrastructural identification of developing proximal tubules based on three-dimensional reconstruction.
Veterinary Medicine and Science,
7(5), 1989-1998.
https://doi.org/10.1002/vms3.558
Seppälä, T. T., Dominguez-Valentin, M., Crosbie, E. J., Engel, C., Aretz, S., Macrae, F., Winship, I., Capella, G., Thomas, H., Hovig, E., Nielsen, M., Sijmons, R. H., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Mints, M., Gluck, N., Katz, L. ... Møller, P. (2021).
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
European Journal of Cancer,
148, 124-133.
https://doi.org/10.1016/j.ejca.2021.02.022
Nielsen, A. J., Nielsen, M. C., Birn, H., Ivarsen, P., Møller, H. J. & Hviid, C. V. B. (2021).
Urine soluble CD163 (sCD163) as biomarker in glomerulonephritis: stability, reference interval and diagnostic performance.
Clinical Chemistry and Laboratory Medicine,
59(4), 701-709.
https://doi.org/10.1515/cclm-2020-0466
Pottegård, A., Lund, L. C., Henriksen, D. P., Folkestad, L.
, Hellfritzsch, M., Hallas, J. & Kristensen, K. B. (2021).
Use of dipeptidyl peptidase-4 inhibitors and risk of splanchnic vein thrombosis: A Danish nationwide new-user active comparator cohort study.
Diabetes, Obesity and Metabolism,
23(2), 648-652.
https://doi.org/10.1111/dom.14253
Arslanova, A., Shafaattalab, S., Ye, K., Asghari, P., Lin, L., Kim, B. R., Roston, T. M., Hove-Madsen, L., Van Petegem, F., Sanatani, S., Moore, E., Lynn, F., Søndergaard, M.
, Luo, Y., Chen, S. R. W. & Tibbits, G. F. (2021).
Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia.
Current Protocols,
1(12), Article e320.
https://doi.org/10.1002/cpz1.320
Lykke, M. R., Becher, N. H., Haahr, T., Boedtkjer, E., Jensen, J. S.
& Uldbjerg, N. (2021).
Vaginal, cervical and uterine pH in women with normal and abnormal vaginal microbiota.
Pathogens,
10(2), Article 90.
https://doi.org/10.3390/pathogens10020090
Bolin, K., Imgenberg-Kreuz, J., Leonard, D., Sandling, J. K., Alexsson, A., Pucholt, P., Haarhaus, M. L., Almlöf, J. C., Nititham, J., Jönsen, A., Sjöwall, C., Bengtsson, A. A., Rantapää-Dahlqvist, S., Svenungsson, E., Gunnarsson, I., Syvänen, A.-C., Lerang, K.
, Troldborg, A., Voss, A. ... Nordmark, G. (2021).
Variants in BANK1 are associated with lupus nephritis of European ancestry.
Genes and Immunity,
22(3), 194-202.
https://doi.org/10.1038/s41435-021-00142-8