Peer-reviewed publikationer

Peer-reviewed publications

the GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J. H. (2024). Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis. Translational Psychiatry, 14(1), Artikel 296. https://doi.org/10.1038/s41398-024-02981-1

Billing, A. M., Kim, Y. C., Gullaksen, S., Schrage, B., Raabe, J., Hutzfeldt, A., Demir, F., Kovalenko, E., Lassé, M., Dugourd, A., Fallegger, R., Klampe, B., Jaegers, J., Li, Q., Kravtsova, O., Crespo-Masip, M., Palermo, A., Fenton, R. A., Hoxha, E. ... Rinschen, M. M. (2024). Metabolic Communication by SGLT2 Inhibition. Circulation, 149(11), 860-884. https://doi.org/10.1161/CIRCULATIONAHA.123.065517

Actis Dato, V., Lange, S. & Cho, Y. (2024). Metabolic Flexibility of the Heart: The Role of Fatty Acid Metabolism in Health, Heart Failure, and Cardiometabolic Diseases. International Journal of Molecular Sciences , 25(2), Artikel 1211. https://doi.org/10.3390/ijms25021211

Chrysopoulou, M. & Rinschen, M. M. (2024). Metabolic Rewiring and Communication: An Integrative View of Kidney Proximal Tubule Function. Annual Review of Physiology, 86, 405-427. https://doi.org/10.1146/annurev-physiol-042222-024724

Nissen Pedersen, A. K., Gormsen, L. C., Nielsen, S., Jessen, N. & Bjerre, M. (2024). Metformin Improves the Prerequisites for FGF21 Signaling in Patients with Type 2 Diabetes. The Journal of clinical endocrinology and metabolism, 109(2), e552-e561. https://doi.org/10.1210/clinem/dgad583

Kalkbrenner, A. E., Zheng, C., Yu, J., Jenson, T. E., Kuhlwein, T., Ladd-Acosta, C., Grove, J. & Schendel, D. (2024). Method for Testing Etiologic Heterogeneity Among Non-Competing Diagnoses, Applied to Impact of Perinatal Exposures on Autism and Attention Deficit Hyperactivity Disorder. Epidemiology, 35(5), 689-700. Artikel 1760. https://doi.org/10.1097/EDE.0000000000001760

Christensen, K. B., Ünsal, Ş., Ebbesen, M. F., Hemstra, L., Schlosser, A., Rosenstand, K., Hansen, P. B. L., Jensen, B. L., Bloksgaard, M., Simonsen, U. & Sorensen, G. L. (2024). MFAP4-Deficiency Aggravates Age-Induced Changes in Resistance Artery Structure, While Ameliorating Hypertension. Hypertension, 81(6), 1308-1319. https://doi.org/10.1161/HYPERTENSIONAHA.123.22283

Bøgh, N., Sørensen, C. B., Alstrup, A. K. O., Søvsø Szocska Hansen, E., Andersen, O. M. & Laustsen, C. (2024). Mice and minipigs with compromised expression of the Alzheimer's disease gene SORL1 show cerebral metabolic disturbances on hyperpolarized [1-¹³C]pyruvate and sodium MRI. Brain Communications, 6(2), Artikel fcae114. https://doi.org/10.1093/braincomms/fcae114

Linder, A., Portmann, K., Schlotheuber, L. J., Streuli, A., Glänzer, W. S., Eyer, K. & Lüchtefeld, I. (2024). Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells. Journal of Visualized Experiments, 2024(205), Artikel e66492. https://doi.org/10.3791/66492

Fruhwürth, S., Zetterberg, H. & Paludan, S. R. (2024). Microglia and amyloid plaque formation in Alzheimer's disease – Evidence, possible mechanisms, and future challenges. Journal of Neuroimmunology, 390, Artikel 578342. https://doi.org/10.1016/j.jneuroim.2024.578342

Gudbergsson, J. M. & Etzerodt, A. (2024). Migrasomes should not be classified as extracellular vesicles. Journal of Cellular and Molecular Medicine, 28(9), e18337. Artikel e18337. https://doi.org/10.1111/jcmm.18337

MISEV Consortium (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2), Artikel e12404. https://doi.org/10.1002/jev2.12404

Munkholm, K., Ussing, A., Brink, M., Edemann-Callesen, H., Canbolat, S. S., Christensen, R., Dahl, K. S., Ebdrup, B. H., Jensen, M. E. J., Kierulf-Lassen, C., Madsen, G. K., Nielsen, S. M., Paulsen, C. P., Rohde, J. F., Tarp, S. & Baandrup, L. (2024). Minor tranquillizers for short-term treatment of newly onset symptoms of anxiety and distress: a systematic review with network meta-analysis of randomized trials. European Archives of Psychiatry and Clinical Neuroscience, 274(3), 475-486. https://doi.org/10.1007/s00406-023-01680-0

Jensen, N. M., Fu, Y. H., Betzer, C., Li, H., Elfarrash, S., Shaib, A. H., Krah, D., Vitic, Z., Reimer, L., Gram, H., Buchman, V., Denham, M., Rizzoli, S. O., Halliday, G. M. & Jensen, P. H. (2024). MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity. npj Parkinson's Disease , 10(1), Artikel 227. https://doi.org/10.1038/s41531-024-00841-9

Little, R. & Ellison, D. H. (2024). Modifying Dietary Sodium and Potassium Intake: An End to the 'Salt Wars'? Hypertension, 81(3), 415-425. https://doi.org/10.1161/HYPERTENSIONAHA.123.19487

Arjmand, S., Biojone, C. & Wegener, G. (2024). Modulation of Leucine Sensors to Mitigate Antipsychotics-Induced Metabolic Syndrome: A New Vista. ACS Pharmacology and Translational Science, 7(1), 294-297. https://doi.org/10.1021/acsptsci.3c00319

Cóppola Segovia, V. & Reggiori, F. (2024). Molecular insights into aggrephagy: Their cellular functions in the context of neurodegenerative diseases. Journal of Molecular Biology, 436(15), Artikel 168493. https://doi.org/10.1016/j.jmb.2024.168493

Nielsen, J., Lauritsen, J., Pedersen, J. N., Nowak, J. S., Bendtsen, M. K., Kleijwegt, G., Lusser, K., Pitarch, L. C., Moreno, J. V., Schneider, M. M., Krainer, G., Goksøyr, L., Khalifé, P., Kaalund, S. S., Aznar, S., Kjærgaard, M., Sereikaité, V., Strømgaard, K., Knowles, T. P. J. ... Otzen, D. E. (2024). Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers. npj Parkinson's Disease , 10(1), Artikel 139. https://doi.org/10.1038/s41531-024-00747-6

Herlin, M. K., Bernth Jensen, J. M., Andreasen, L., Petersen, M. S., Lønskov, J., Thorup, M. B., Birkebæk, N., Mogensen, T. H., Herlin, T. & Deleuran, B. (2024). Monozygotic triplets with juvenile-onset autoimmunity and 18p microdeletion involving PTPRM. Frontiers in Genetics, 15, Artikel 1437566. https://doi.org/10.3389/fgene.2024.1437566

Pupak, A., Rodríguez-Navarro, I., Sathasivam, K., Singh, A., Essmann, A., del Toro, D., Ginés, S., Mouro Pinto, R., Bates, G. P., Vang Ørom, U. A., Martí, E. & Brito, V. (2024). m⁶A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts. EMBO Reports, 25(11), 5026-5052. https://doi.org/10.1038/s44319-024-00283-7

Macht, A., Huang, Y., Reinert, L. S., Grass, V., Lohmer, K., Aristizabal Prada, E. T., Babel, E., Semmler, A., Zhang, W., Wegner, A., Lichtenegger-Hartl, E., Haas, S., Hasenpusch, G., Meyer, S., Paludan, S. R., Pichlmair, A., Rudolph, C. & Langenickel, T. (2024). Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice. EMBO Reports, 25(9), 3777-3788. https://doi.org/10.1038/s44319-024-00216-4

Waheed, N., Waris, R., Naseer, M., Razzaq, A., Haider, N., Shah, A. A. & Ullah, A. (2024). Mutational spectrum of CFTR in cystic fibrosis patients with gastrointestinal and hepatobiliary manifestations. Molecular Biology Reports, 51(1), Artikel 573. https://doi.org/10.1007/s11033-024-09508-3

Biojone, C., Cannarozzo, C., Seiffert, N., Diniz, C. R. A. F., Brunello, C. A., Castrén, E. & Casarotto, P. (2024). Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB. Cellular and Molecular Neurobiology, 44(1), Artikel 4. https://doi.org/10.1007/s10571-023-01438-1

Liang, X., Pacuła-Miszewska, A. J., Vartak, R., Prajapati, M., Zheng, H., Zhao, C., Mao, G., Patel, K., Fedosova, N., Ścianowski, J. & Billack, B. (2024). N-3-Methylbutyl-benzisoselenazol-3(2H)-one Exerts Antifungal Activity In Vitro and in a Mouse Model of Vulvovaginal Candidiasis. Current issues in molecular biology, 46(3), 2480-2496. https://doi.org/10.3390/cimb46030157

Kudrin, P., Singh, A., Meierhofer, D., Kuśnierczyk, A. & Ørom, U. A. V. (2024). N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules. EMBO Reports, 25(4), 1814-1834. https://doi.org/10.1038/s44319-024-00098-6

Nielsen, H. N., Holm, R., Sweazey, R., Andersen, J. P., Artigas, P. & Vilsen, B. (2024). Na+,K+-ATPase with Disrupted Na+ Binding Sites I and III Binds Na+ with Increased Affinity at Site II and Undergoes Na+-Activated Phosphorylation with ATP. Biomolecules, 14(1), Artikel 135. https://doi.org/10.3390/biom14010135

Aaen, P., Kristensen, K. B., Antony, A., Hansen, S. H., Cornett, C., Pedersen, S. F. & Boedtkjer, E. (2024). Na⁺/H⁺-exchange inhibition by cariporide is compensated via Na⁺,HCO₃⁻-cotransport and has no net growth consequences for ErbB2-driven breast carcinomas. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1870(7), Artikel 167450. https://doi.org/10.1016/j.bbadis.2024.167450

Khan, A. M., Steffensen, M. A., Paskeviciute, E., Abduljabar, A. B., Sørensen, T. L., Vorum, H., Nissen, M. H. & Honoré, B. (2024). Neuroretinal degeneration in a mouse model of systemic chronic immune activation observed by proteomics. Frontiers in Immunology, 15, Artikel 1374617. https://doi.org/10.3389/fimmu.2024.1374617

Guldager, M. B., Biojone, C., Rodrigues Da Silva, N., Dornela Godoy, L. & Joca, S. (2024). New insights into the involvement of serotonin and BDNF-TrkB signalling in cannabidiol's antidepressant effect. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 133, Artikel 111029. https://doi.org/10.1016/j.pnpbp.2024.111029

Herlin, L. K., Sørensen, S. B., Graakjaer, J. A., Andersen, S., Schmidt, S. A. J., Sommerlund, M. & Mogensen, T. H. (2024). NF-κB Activation and X-Inactivation in Females with Incontinentia Pigmenti and Recurrent Infections. Journal of Clinical Immunology, 44(6), 136. Artikel 136. https://doi.org/10.1007/s10875-024-01737-2

Johnsen, L. Ø., Sigad, A., Friis, K. A., Berg, P. M. & Damkier, H. H. (2024). NH4Cl-induced metabolic acidosis increases the abundance of HCO3 - transporters in the choroid plexus of mice. Frontiers in Physiology, 15, Artikel 1491793. https://doi.org/10.3389/fphys.2024.1491793

Faress, I., Khalil, V., Hou, W. H., Moreno, A., Andersen, N., Fonseca, R., Piriz, J., Capogna, M. & Nabavi, S. (2024). Non-Hebbian plasticity transforms transient experiences into lasting memories. eLife, 12, Artikel RP91421. https://doi.org/10.7554/eLife.91421

Juul-Kristensen, T., Thiesen, C., Haurum, L. W., Keller-Socin, J. G., Lendamba, R. W., Zoleko Manego, R., Betouke, M. E., Knudsen, B. R., Pareja, E., Pareja-Tobes, E., Labouriau, R., Ghyslain, M.-N. & Tesauro, C. (2024). Non-Invasive Malaria Detection in Sub-Saharan Africa Using a DNA-Based Sensor System. Sensors, 24(24), Artikel 7947. https://doi.org/10.3390/s24247947

Trist, B. G., Wright, C. J., Rangel, A., Cottle, L., Prasad, A., Jensen, N. M., Gram, H., Dzamko, N., Jensen, P. H. & Kirik, D. (2024). Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain. npj Parkinson's Disease , 10(1), Artikel 217. https://doi.org/10.1038/s41531-024-00830-y

Holm-Weber, T., Skov, F., Mohanakumar, S., Thorup, L., Riis, T., Christensen, M. B., Peick Sonne, D., Jensen, P. B., Bødtkjer, D. M. B. & Hjortdal, V. E. (2024). Octreotide improves human lymphatic fluid transport: a translational trial. European Journal of Cardio-Thoracic Surgery, 65(1), Artikel ezad380. https://doi.org/10.1093/ejcts/ezad380

Kurmasheva, N., Said, A., Wong, B., Kinderman, P., Han, X., Rahimic, A. H. F., Kress, A., Carter-Timofte, M. E., Holm, E., van der Horst, D., Kollmann, C. F., Liu, Z., Wang, C., Hoang, H.-D., Kovalenko, E., Chrysopoulou, M., Twayana, K. S., Ottosen, R. N., Svenningsen, E. B. ... Olagnier, D. (2024). Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature Communications, 15(1), Artikel 4096. https://doi.org/10.1038/s41467-024-48422-x

Abdelfattah, F., Schulz, H., Wehland, M., Corydon, T. J., Sahana, J., Kraus, A., Krüger, M., González-Torres, L. F., Cortés-Sánchez, J. L., Wise, P. M., Mushunuri, A., Hemmersbach, R., Liemersdorf, C., Infanger, M. & Grimm, D. (2024). Omics Studies of Specialized Cells and Stem Cells under Microgravity Conditions. International Journal of Molecular Sciences , 25(18), Artikel 10014. https://doi.org/10.3390/ijms251810014

Graf, J., Schulz, H., Wehland, M., Corydon, T. J., Sahana, J., Abdelfattah, F., Wuest, S. L., Egli, M., Krüger, M., Kraus, A., Wise, P. M., Infanger, M. & Grimm, D. (2024). Omics Studies of Tumor Cells under Microgravity Conditions. International Journal of Molecular Sciences , 25(2), Artikel 926. https://doi.org/10.3390/ijms25020926

Rohr, L., Ehinger, A., Rausch, L., Glöckner Burmeister, N., Meixner, A. J., Gronnier, J., Harter, K., Kemmerling, B. & zur Oven-Krockhaus, S. (2024). OneFlowTraX: a user-friendly software for super-resolution analysis of single-molecule dynamics and nanoscale organization. Frontiers in Plant Science, 15, Artikel 1358935. https://doi.org/10.3389/fpls.2024.1358935

Mogensen, L. S., Mikkelsen, S. A., Tadini-Buoninsegni, F., Holm, R., Matsell, E., Vilsen, B., Molday, R. S. & Andersen, J. P. (2024). On the track of the lipid transport pathway of the phospholipid flippase ATP8A2: Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4. Biochimica et Biophysica Acta. Molecular Cell Research, 1871(1), Artikel 119570. https://doi.org/10.1016/j.bbamcr.2023.119570

Gies, S. E., Hänzelmann, S., Kylies, D., Lassé, M., Lagies, S., Hausmann, F., Khatri, R., Zolotarev, N., Poets, M., Zhang, T., Demir, F., Billing, A. M., Quaas, J., Meister, E., Engesser, J., Mühlig, A. K., Lu, S., Liu, S., Chilla, S. ... Huber, T. B. (2024). Optimized protocol for the multiomics processing of cryopreserved human kidney tissue. American Journal of Physiology - Renal Physiology, 327(5), F822-F844. https://doi.org/10.1152/ajprenal.00404.2023

Vestergaard, A. E. F., Jensen, S. K., Heide-Jørgensen, U., Adelborg, K., Birn, H., Carrero, J.-J. & Christiansen, C. F. (2024). Oral anticoagulant treatment and risk of kidney disease-a nationwide, population-based cohort study. Clinical Kidney Journal, 17(1), Artikel sfad252. https://doi.org/10.1093/ckj/sfad252

Domingos, L. B., Silva Júnior, A. F. D., Diniz, C. R. A. F., Rosa, J., Terzian, A. L. B. & Moraes Resstel, L. B. (2024). P2X7 receptors modulate acquisition of cue fear extinction and contextual background memory generalization in male mice. Neuropharmacology, 261, Artikel 110177. https://doi.org/10.1016/j.neuropharm.2024.110177

Kraus, A., Skoczynski, K., Brötsch, M., Burzlaff, N., Leipziger, J., Schiffer, M., Büttner-Herold, M. & Buchholz, B. (2024). P2Y2R and Cyst Growth in Polycystic Kidney Disease. Journal of the American Society of Nephrology : JASN, 35(10), 1351-1365. https://doi.org/10.1681/ASN.0000000000000416

Mårup, F. H., Peters, C. D., Nielsen, S. F., Nygaard, L., Madsen, B., Mose, F. H. & Birn, H. (2024). Patiromer to Reduce Albuminuria through Increased Renin Angiotensin Aldosterone System Inhibition in Patients With CKD-A Feasibility Trial. Kidney International Reports, 9(8), 2399-2409. https://doi.org/10.1016/j.ekir.2024.05.006

Kraft, C. & Reggiori, F. (2024). Phagophore closure, autophagosome maturation and autophagosome fusion during macroautophagy in the yeast Saccharomyces cerevisiae. FEBS Letters, 598(1), 73-83. https://doi.org/10.1002/1873-3468.14720

Hansen, J. S., Boix, F., Hasselstrøm, J. B., Sørensen, L. K., Kjolby, M., Gustavsen, S., Hansen, R. M., Petersen, T., Sellebjerg, F., Kasch, H., Rasmussen, P. V., Finnerup, N. B., Saedder, E. A. & Svendsen, K. B. (2024). Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial. Clinical and Translational Science, 17(1), Artikel e13685. https://doi.org/10.1111/cts.13685

Prat-Duran, J., Binotti Abreu De Araujo, I. B., Juste, N., Pinilla, E., Rios, F. J., Montezano, A. C., Touyz, R. M., Simonsen, U., Nørregaard, R. & Buus, N. H. (2024). Pharmacological modulation of transglutaminase 2 in the unilateral ureteral obstruction mouse model. European Journal of Pharmacology, 984, Artikel 177037. https://doi.org/10.1016/j.ejphar.2024.177037

Liu, Y. B., Arystarkhova, E., Sacino, A. N., Szabari, M. V., Lutz, C. M., Terrey, M., Morsci, N., Jakobs, T. C., Lykke-Hartmann, K., Brashear, A., Napoli, E. & Sweadner, K. J. (2024). Phenotype distinctions in mice deficient in the neuron-specific α3 subunit of Na,K-ATPase: Atp1a3 ^tm1Ling/+and Atp1a3^+/D801Y. eNeuro , 11(8). https://doi.org/10.1523/ENEURO.0101-24.2024

iPSYCH Consortium (2024). Phenotypic and ancestry-related assortative mating in autism. Molecular Autism, 15(1), 27. Artikel 27. https://doi.org/10.1186/s13229-024-00605-5

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Revideret 21.08.2025