Peer-reviewed publikationer

Peer-reviewed publications

Papini, N. M., Presseller, E., Bulik, C. M., Holde, K., Larsen, J. T., Thornton, L. M., Albiñana, C., Vilhjálmsson, B. J., Mortensen, P. B., Yilmaz, Z. & Petersen, L. V. (2024). Interplay of polygenic liability with birth-related, somatic, and psychosocial factors in anorexia nervosa risk: a nationwide study. Psychological Medicine, 54(9), 2073-2086. https://doi.org/10.1017/S0033291724000175

Troldborg, A., Godnic-Polai, Z., Cervenak, L., Hansen, A. G., Farkas, H. & Thiel, S. (2024). Inter-α-trypsin inhibitor heavy chain 4 (ITIH4) as a compensatory protease inhibitor in hereditary angioedema. The Journal of Allergy and Clinical Immunology, 154(2), 468-479.e6. https://doi.org/10.1016/j.jaci.2024.03.028

Thygesen, M., Entezari, S., Houlind, N. K., Nielsen, T. H., Olsen, N. Ø., Nielsen, T. D., Skov, M., Tankisi, A., Rasmussen, M., Einarsson, H. B., Orlowski, D., Dyrskog, S. E., Thorup, L., Pedersen, M. & Rasmussen, M. M. (2024). Intraspinal pressure is not elevated after traumatic spinal cord injury in a porcine model sham-controlled trial. Poster-session præsenteret på Eurospine 2024, Østrig.

Byeon, C. H., Hansen, K. H., Jeffrey, J., Saricayir, H., Andreasen, M. & Akbey, Ü. (2024). Intrinsically disordered Pseudomonas chaperone FapA slows down the fibrillation of major biofilm-forming functional amyloid FapC. FEBS journal, 291(9), 1925-1943. https://doi.org/10.1111/febs.17084

Swaminathan, P., Klingstedt, T., Theologidis, V., Gram, H., Larsson, J., Hagen, L., Liabakk, N. B., Gederaas, O. A., Hammarström, P., Nilsson, K. P. R., Van Den Berge, N. & Lindgren, M. (2024). In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging. International Journal of Molecular Sciences , 25(22), Artikel 12458. https://doi.org/10.3390/ijms252212458

On behalf of the ADA/EASD PMDI (2024). Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review. Communications Medicine, 4(1), Artikel 66. https://doi.org/10.1038/s43856-024-00478-y

Pedersen, L. H. & Liew, Z. (2024). Is man the only animal with ears that cannot move them? Reflections on observational studies in obstetrics and gynecology. Acta Obstetricia et Gynecologica Scandinavica, 103(8), 1478-1479. https://doi.org/10.1111/aogs.14925

Mikkelsen, J. H., Stødkilde, K., Jensen, M. P., Hansen, A. G., Wu, Q., Lorentzen, J., Graversen, J. H., Andersen, G. R., Fenton, R. A., Etzerodt, A., Thiel, S. & Andersen, C. B. F. (2024). Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis. Journal of Immunology, 212(8), 1334-1344. https://doi.org/10.4049/jimmunol.2300862

Larsen, M. L., Voss, A., Nielsen, C. T. H., Hauge, E. M., Faurschou, M. & Troldborg, A. (2024). Kimærisk antigenreceptor T-cellebehandling til refraktære systemiske autoimmune reumatologiske sygdomme. Ugeskrift for Læger, 186(47). https://doi.org/10.61409/V06240429

Rober, J. K., Wulff Kelstrup, G. & Høy, K. (2024). Kirurgi øger symptomatiske patienters livskvalitet ved spondylolistese. Ugeskrift for Læger, 186(39), Artikel V04240279. https://doi.org/10.61409/V04240279

Andersen, O. M., Monti, G., Jensen, A. M. G., de Waal, M. W. J., Hulsman, M., Olsen, J. G. & Holstege, H. (2024). Known disease-causing variants in homologous proteins help predict pathogenicity of SORL1 variants in Alzheimer’s disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(S1), Artikel e084835. https://doi.org/10.1002/alz.084835

van der Horst, D., Carter-Timofte, M. E., Danneels, A., Silva da Costa, L., Kurmasheva, N., Thielke, A. L., Hansen, A. L., Chorošajev, V., Holm, C. K., Belouzard, S., de Weber, I., Beny, C. & Olagnier, D. (2024). Large-scale deep learning identifies the antiviral potential of PKI-179 and MTI-31 against coronaviruses. Antiviral Research, 231, Artikel 106012. https://doi.org/10.1016/j.antiviral.2024.106012

Glintborg, B., Hansson, M., Hammer, H. B., Klareskog, L., Saevarsdottir, S., Westerlind, H., Rönnelid, J., Gehring, I., Benson, M., Esbensen, B. A., Hetland, M. L., Padyukov, L., Kragstrup, T. W., Hauge, E.-M., Axnäs, B. B., Krogh, N. S., Johannesson, M. & Askling, J. (2024). Legal obstacles jeopardise research in personalised medicine - experiences from a Nordic collaboration within rheumatology. Scandinavian Journal of Public Health, 52(8), 1019-1025. https://doi.org/10.1177/14034948231212711

Hebib, L., Herraiz-Adillo, Á., Higueras-Fresnillo, S., Berglind, D., Daka, B., Wennberg, P., Hagström, E., Lenander, C., Ahlqvist, V. H., Östgren, C. J., Rådholm, K. & Henriksson, P. (2024). Life’s Essential 8 is inversely associated with high-sensitivity C-reactive protein. Scientific Reports, 14(1), Artikel 15024. https://doi.org/10.1038/s41598-024-65977-3

Ou, A. H., Rosenthal, S. B., Adli, M., Akiyama, K., Akula, N., Alda, M., Amare, A. T., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Cervantes, P. ... Kelsoe, J. R. (2024). Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study. Translational Psychiatry, 14(1), Artikel 109. https://doi.org/10.1038/s41398-024-02811-4

Bakiri, L., Hasenfuss, S. C., Guío-Carrión, A., Thomsen, M. K., Hasselblatt, P. & Wagner, E. F. (2024). Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc. Proceedings of the National Academy of Sciences (PNAS), 121(18), Artikel e2404188121. https://doi.org/10.1073/pnas.2404188121

Jørgensen, R. M., Støvring, H., Østergaard, J. N., Hede, S., Svendsen, K., Vestergaard, E. T. & Bruun, J. M. (2024). Long-term change in BMI for children with obesity treated in family-centered lifestyle interventions. Obesity Facts, 17(6), 570-581. https://doi.org/10.1159/000540389

Dørflinger, G. H., Holt, C. B., Thiel, S., Bech, J. N., Østergaard, J. A. & Bjerre, M. (2024). Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes. International Journal of Molecular Sciences , 25(13), Artikel 7204. https://doi.org/10.3390/ijms25137204

El-Masri, B. M., Andreasen, C. M., Laursen, K. S., Kofod, V. B., Dahl, X. G., Nielsen, M. H., Thomsen, J. S., Brüel, A., Sørensen, M. S., Hansen, L. J., Kim, A. S., Taylor, V. E., Massarotti, C., McDonald, M. M., You, X., Charles, J. F., Delaisse, J. M. & Andersen, T. L. (2024). Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect. Bone Research, 12(1), Artikel 62. https://doi.org/10.1038/s41413-024-00362-4

Holt, C. B., Halkjær, L., Dudley, T., Schwaeble, W., Krarup Hansen, T., Thiel, S. & Østergaard, J. A. (2024). MASP-2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes. Scandinavian Journal of Immunology, 99(4), Artikel e13348. https://doi.org/10.1111/sji.13348

Sønderskov, M. B., Hasselstrøm, J. B., Bahij, R. & Andersen, C. U. (2024). Medicinal cannabis tea contains variable doses of cannabinoids and no terpenes. Basic and Clinical Pharmacology and Toxicology, 135(3), 334-344. https://doi.org/10.1111/bcpt.14056

the GSRD Consortium, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J. H. (2024). Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis. Translational Psychiatry, 14(1), Artikel 296. https://doi.org/10.1038/s41398-024-02981-1

Billing, A. M., Kim, Y. C., Gullaksen, S., Schrage, B., Raabe, J., Hutzfeldt, A., Demir, F., Kovalenko, E., Lassé, M., Dugourd, A., Fallegger, R., Klampe, B., Jaegers, J., Li, Q., Kravtsova, O., Crespo-Masip, M., Palermo, A., Fenton, R. A., Hoxha, E. ... Rinschen, M. M. (2024). Metabolic Communication by SGLT2 Inhibition. Circulation, 149(11), 860-884. https://doi.org/10.1161/CIRCULATIONAHA.123.065517

Actis Dato, V., Lange, S. & Cho, Y. (2024). Metabolic Flexibility of the Heart: The Role of Fatty Acid Metabolism in Health, Heart Failure, and Cardiometabolic Diseases. International Journal of Molecular Sciences , 25(2), Artikel 1211. https://doi.org/10.3390/ijms25021211

Chrysopoulou, M. & Rinschen, M. M. (2024). Metabolic Rewiring and Communication: An Integrative View of Kidney Proximal Tubule Function. Annual Review of Physiology, 86, 405-427. https://doi.org/10.1146/annurev-physiol-042222-024724

Nissen Pedersen, A. K., Gormsen, L. C., Nielsen, S., Jessen, N. & Bjerre, M. (2024). Metformin Improves the Prerequisites for FGF21 Signaling in Patients with Type 2 Diabetes. The Journal of clinical endocrinology and metabolism, 109(2), e552-e561. https://doi.org/10.1210/clinem/dgad583

Kalkbrenner, A. E., Zheng, C., Yu, J., Jenson, T. E., Kuhlwein, T., Ladd-Acosta, C., Grove, J. & Schendel, D. (2024). Method for Testing Etiologic Heterogeneity Among Non-Competing Diagnoses, Applied to Impact of Perinatal Exposures on Autism and Attention Deficit Hyperactivity Disorder. Epidemiology, 35(5), 689-700. Artikel 1760. https://doi.org/10.1097/EDE.0000000000001760

Christensen, K. B., Ünsal, Ş., Ebbesen, M. F., Hemstra, L., Schlosser, A., Rosenstand, K., Hansen, P. B. L., Jensen, B. L., Bloksgaard, M., Simonsen, U. & Sorensen, G. L. (2024). MFAP4-Deficiency Aggravates Age-Induced Changes in Resistance Artery Structure, While Ameliorating Hypertension. Hypertension, 81(6), 1308-1319. https://doi.org/10.1161/HYPERTENSIONAHA.123.22283

Bøgh, N., Sørensen, C. B., Alstrup, A. K. O., Søvsø Szocska Hansen, E., Andersen, O. M. & Laustsen, C. (2024). Mice and minipigs with compromised expression of the Alzheimer's disease gene SORL1 show cerebral metabolic disturbances on hyperpolarized [1-¹³C]pyruvate and sodium MRI. Brain Communications, 6(2), Artikel fcae114. https://doi.org/10.1093/braincomms/fcae114

Linder, A., Portmann, K., Schlotheuber, L. J., Streuli, A., Glänzer, W. S., Eyer, K. & Lüchtefeld, I. (2024). Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells. Journal of Visualized Experiments, 2024(205), Artikel e66492. https://doi.org/10.3791/66492

Fruhwürth, S., Zetterberg, H. & Paludan, S. R. (2024). Microglia and amyloid plaque formation in Alzheimer's disease – Evidence, possible mechanisms, and future challenges. Journal of Neuroimmunology, 390, Artikel 578342. https://doi.org/10.1016/j.jneuroim.2024.578342

Gudbergsson, J. M. & Etzerodt, A. (2024). Migrasomes should not be classified as extracellular vesicles. Journal of Cellular and Molecular Medicine, 28(9), e18337. Artikel e18337. https://doi.org/10.1111/jcmm.18337

MISEV Consortium (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2), Artikel e12404. https://doi.org/10.1002/jev2.12404

Munkholm, K., Ussing, A., Brink, M., Edemann-Callesen, H., Canbolat, S. S., Christensen, R., Dahl, K. S., Ebdrup, B. H., Jensen, M. E. J., Kierulf-Lassen, C., Madsen, G. K., Nielsen, S. M., Paulsen, C. P., Rohde, J. F., Tarp, S. & Baandrup, L. (2024). Minor tranquillizers for short-term treatment of newly onset symptoms of anxiety and distress: a systematic review with network meta-analysis of randomized trials. European Archives of Psychiatry and Clinical Neuroscience, 274(3), 475-486. https://doi.org/10.1007/s00406-023-01680-0

Jensen, N. M., Fu, Y. H., Betzer, C., Li, H., Elfarrash, S., Shaib, A. H., Krah, D., Vitic, Z., Reimer, L., Gram, H., Buchman, V., Denham, M., Rizzoli, S. O., Halliday, G. M. & Jensen, P. H. (2024). MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity. npj Parkinson's Disease , 10(1), Artikel 227. https://doi.org/10.1038/s41531-024-00841-9

Little, R. & Ellison, D. H. (2024). Modifying Dietary Sodium and Potassium Intake: An End to the 'Salt Wars'? Hypertension, 81(3), 415-425. https://doi.org/10.1161/HYPERTENSIONAHA.123.19487

Arjmand, S., Biojone, C. & Wegener, G. (2024). Modulation of Leucine Sensors to Mitigate Antipsychotics-Induced Metabolic Syndrome: A New Vista. ACS Pharmacology and Translational Science, 7(1), 294-297. https://doi.org/10.1021/acsptsci.3c00319

Cóppola Segovia, V. & Reggiori, F. (2024). Molecular insights into aggrephagy: Their cellular functions in the context of neurodegenerative diseases. Journal of Molecular Biology, 436(15), Artikel 168493. https://doi.org/10.1016/j.jmb.2024.168493

Nielsen, J., Lauritsen, J., Pedersen, J. N., Nowak, J. S., Bendtsen, M. K., Kleijwegt, G., Lusser, K., Pitarch, L. C., Moreno, J. V., Schneider, M. M., Krainer, G., Goksøyr, L., Khalifé, P., Kaalund, S. S., Aznar, S., Kjærgaard, M., Sereikaité, V., Strømgaard, K., Knowles, T. P. J. ... Otzen, D. E. (2024). Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers. npj Parkinson's Disease , 10(1), Artikel 139. https://doi.org/10.1038/s41531-024-00747-6

Herlin, M. K., Bernth Jensen, J. M., Andreasen, L., Petersen, M. S., Lønskov, J., Thorup, M. B., Birkebæk, N., Mogensen, T. H., Herlin, T. & Deleuran, B. (2024). Monozygotic triplets with juvenile-onset autoimmunity and 18p microdeletion involving PTPRM. Frontiers in Genetics, 15, Artikel 1437566. https://doi.org/10.3389/fgene.2024.1437566

Pupak, A., Rodríguez-Navarro, I., Sathasivam, K., Singh, A., Essmann, A., del Toro, D., Ginés, S., Mouro Pinto, R., Bates, G. P., Vang Ørom, U. A., Martí, E. & Brito, V. (2024). m⁶A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts. EMBO Reports, 25(11), 5026-5052. https://doi.org/10.1038/s44319-024-00283-7

Macht, A., Huang, Y., Reinert, L. S., Grass, V., Lohmer, K., Aristizabal Prada, E. T., Babel, E., Semmler, A., Zhang, W., Wegner, A., Lichtenegger-Hartl, E., Haas, S., Hasenpusch, G., Meyer, S., Paludan, S. R., Pichlmair, A., Rudolph, C. & Langenickel, T. (2024). Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice. EMBO Reports, 25(9), 3777-3788. https://doi.org/10.1038/s44319-024-00216-4

Waheed, N., Waris, R., Naseer, M., Razzaq, A., Haider, N., Shah, A. A. & Ullah, A. (2024). Mutational spectrum of CFTR in cystic fibrosis patients with gastrointestinal and hepatobiliary manifestations. Molecular Biology Reports, 51(1), Artikel 573. https://doi.org/10.1007/s11033-024-09508-3

Biojone, C., Cannarozzo, C., Seiffert, N., Diniz, C. R. A. F., Brunello, C. A., Castrén, E. & Casarotto, P. (2024). Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB. Cellular and Molecular Neurobiology, 44(1), Artikel 4. https://doi.org/10.1007/s10571-023-01438-1

Liang, X., Pacuła-Miszewska, A. J., Vartak, R., Prajapati, M., Zheng, H., Zhao, C., Mao, G., Patel, K., Fedosova, N., Ścianowski, J. & Billack, B. (2024). N-3-Methylbutyl-benzisoselenazol-3(2H)-one Exerts Antifungal Activity In Vitro and in a Mouse Model of Vulvovaginal Candidiasis. Current issues in molecular biology, 46(3), 2480-2496. https://doi.org/10.3390/cimb46030157

Kudrin, P., Singh, A., Meierhofer, D., Kuśnierczyk, A. & Ørom, U. A. V. (2024). N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules. EMBO Reports, 25(4), 1814-1834. https://doi.org/10.1038/s44319-024-00098-6

Nielsen, H. N., Holm, R., Sweazey, R., Andersen, J. P., Artigas, P. & Vilsen, B. (2024). Na+,K+-ATPase with Disrupted Na+ Binding Sites I and III Binds Na+ with Increased Affinity at Site II and Undergoes Na+-Activated Phosphorylation with ATP. Biomolecules, 14(1), Artikel 135. https://doi.org/10.3390/biom14010135

Aaen, P., Kristensen, K. B., Antony, A., Hansen, S. H., Cornett, C., Pedersen, S. F. & Boedtkjer, E. (2024). Na⁺/H⁺-exchange inhibition by cariporide is compensated via Na⁺,HCO₃⁻-cotransport and has no net growth consequences for ErbB2-driven breast carcinomas. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1870(7), Artikel 167450. https://doi.org/10.1016/j.bbadis.2024.167450

Khan, A. M., Steffensen, M. A., Paskeviciute, E., Abduljabar, A. B., Sørensen, T. L., Vorum, H., Nissen, M. H. & Honoré, B. (2024). Neuroretinal degeneration in a mouse model of systemic chronic immune activation observed by proteomics. Frontiers in Immunology, 15, Artikel 1374617. https://doi.org/10.3389/fimmu.2024.1374617

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Revideret 14.09.2020