Poulsen, E. T., Nielsen, N. S., Scavenius, C., Mogensen, E. H., Risør, M. W., Runager, K., Lukassen, M. V., Rasmussen, C. B., Christiansen, G., Richner, M., Vorum, H.
& Enghild, J. J. (2019).
The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.
Journal of Biological Chemistry,
294(31), 11817-11828.
https://doi.org/10.1074/jbc.RA119.009050
Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D.
, Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi-Hemami, H., Teilum, K. & Ellgaard, L. (2019).
The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework.
Journal of Biological Chemistry,
294(22), 8745-8759.
https://doi.org/10.1074/jbc.RA119.007491
Li, K., Neumann, K., Duhan, V., Namineni, S.
, Hansen, A. L., Wartewig, T., Kurgyis, Z.
, Holm, C. K., Heikenwalder, M., Lang, K. S. & Ruland, J. (2019).
The uric acid crystal receptor Clec12A potentiates type I interferon responses.
Proceedings of the National Academy of Sciences,
116(37), 18544-18549.
https://doi.org/10.1073/pnas.1821351116
Maxel, T.
, Smidt, K., Petersen, C. C., Honoré, B., Christensen, A. K., Jeppesen, P. B., Brock, B., Rungby, J., Palmfeldt, J. & Larsen, A. (2019).
The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells.
Scientific Reports,
9(1), Artikel 8589.
https://doi.org/10.1038/s41598-019-44954-1
Hanifa, M. A., Skott, M., Maltesen, R. G., Rasmussen, B. S., Nielsen, S.
, Frøkiær, J., Ring, T. & Wimmer, R. (2019).
Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model.
Metabolomics,
15(8), Artikel 112.
https://doi.org/10.1007/s11306-019-1569-3
Ørstrup, L. H.
, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B.
, Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, J.
& Glud, A. N. (2019).
Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method.
Heliyon,
5(11), Artikel e02892.
https://doi.org/10.1016/j.heliyon.2019.e02892,
https://doi.org/10.1016/j.heliyon.2019.e02892
Musliner, K., Vilhjálmsson, B. J., Albiñana Climent, C., Krebs, M. D., Zandi, P. P.
, Agerbo, E., Mortensen, P. B., Werge, T.
, Børglum, A. & Østergaard, S. D. (2019).
Towards precision medicine in psychiatric care: Using polygenic risk scores to predict outcomes in hospital-treated depression patients . S88-S88. Abstract fra World Congress of Psychiatric Genetics , Anaheim , California, USA.
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S.
, Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, K. J., Pers, T. H., Khodosevich, K., Simons, B. D. & Jensen, K. B. (2019).
Tracing the origin of adult intestinal stem cells.
Nature,
570(7759), 107-111.
https://doi.org/10.1038/s41586-019-1212-5
van Diggelen, F., Hrle, D., Apetri, M.
, Christiansen, G., Rammes, G., Tepper, A.
& Otzen, D. E. (2019).
Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation.
PLOS ONE,
14(3), Artikel 0213663.
https://doi.org/10.1371/journal.pone.0213663
Budolfsen, C., Faber, J.
, Grimm, D., Krüger, M., Bauer, J., Wehland, M., Infanger, M.
& Magnusson, N. E. (2019).
Tyrosine Kinase Inhibitor-Induced Hypertension: Role of Hypertension as a Biomarker in Cancer Treatment.
Current Vascular Pharmacology,
17(6), 618-634.
https://doi.org/10.2174/1570161117666190130165810
Rodríguez-Rodríguez, R., Ackermann, T. N., Plaza, J. A.
, Simonsen, U., Matchkov, V., Llobera, A. & Munoz-Berbel, X. (2019).
Ultrasensitive photonic microsystem enabling sub-micrometric monitoring of arterial oscillations for advanced cardiovascular studies.
Frontiers in Physiology,
10, Artikel 940.
https://doi.org/10.3389/fphys.2019.00940
Gammelgaard, K. R., Vad-Nielsen, J., Clement, M. S., Weiss, S., Daugaard, T. F., Dagnæs-Hansen, F., Meldgaard, P., Sorensen, B. S. & Nielsen, A. L. (2019).
Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC.
Translational Oncology,
12(3), 432-440.
https://doi.org/10.1016/j.tranon.2018.11.017
Voss, N. C. S., Kold-Petersen, H. H., Henningsen, M. B., Homilius, C. & Boedtkjer, E. (2019).
Upregulated Na+/H+-exchange protects human colon cancer tissue against intracellular acidification.
BioMed Research International,
2019, Artikel 3702783.
https://doi.org/10.1155/2019/3702783
Meier, M., Knudsen, A. R., Andersen, K. J., Ludvigsen, M., Eriksen, P. L., Honoré, B. & Mortensen, F. V. (2019).
Upregulation of ureagenesis may be pivotal for survival of post-hepatectomy liver failure in rats. Poster session præsenteret på 13th Congress of the European – African Hepato-Pancreato-Biliary Association, Amsterdam, Holland.
Hinrichs, G. R.
, Weyer, K., Friis, U. G., Svenningsen, P., Lund, I. K.
, Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L.
& Birn, H. (2019).
Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice.
Acta Physiologica (Online),
227(4), Artikel e13362.
https://doi.org/10.1111/apha.13362
Volqvartz, T., Vestergaard, A. L., Aagaard, S. K., Andreasen, M. F., Lesnikova, I., Uldbjerg, N., Larsen, A. & Bor, P. (2019).
Use of alternative medicine, ginger and licorice among Danish pregnant women - a prospective cohort study.
BMC Complementary and Alternative Medicine,
19(1), Artikel 5.
https://doi.org/10.1186/s12906-018-2419-y
Gaspar, H. A., Gerring, Z., Hübel, C., Middeldorp, C. M., Derks, E. M., Breen, G. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019).
Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder.
Translational Psychiatry,
9(1), Artikel 117.
https://doi.org/10.1038/s41398-019-0451-4
Hannon, E.
, Schendel, D., Ladd-Acosta, C.
, Grove, J., Hansen, C. S., Hougaard, D. M., Bresnahan, M.
, Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M.
, Mortensen, P. B., Børglum, A. D., Werge, T.
, Pedersen, M. G., Nordentoft, M., Buxbaum, J. D., Fallin, M. D., Bybjerg-Grauholm, J. ... Mill, J. (2019).
Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight.
Philosophical Transactions of the Royal Society B: Biological Sciences,
374(1770), Artikel 20180120.
https://doi.org/10.1098/rstb.2018.0120
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A. ... Jacobsson, B. (2019).
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.
Nature Communications,
10(1), 1-13. Artikel 3927.
https://doi.org/10.1038/s41467-019-11881-8
Kjaer, L.
, Skov, V., Andersen, M. T.
, Aggerholm, A., Clair, P., Gniot, M.
, Soeby, K., Udby, L., Dorff, M. H., Hasselbalch, H. & Pallisgaard, N. (2019).
Variant-specific discrepancy when quantitating BCR-ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay.
European Journal of Haematology,
103(1), 26-34.
https://doi.org/10.1111/ejh.13238
Giesecke, T., Himmerkus, N.
, Leipziger, J., Bleich, M., Koshimizu, T. A., Fähling, M., Smorodchenko, A., Shpak, J., Knappe, C., Isermann, J.
, Ayasse, N., Kawahara, K., Schmoranzer, J., Gimber, N., Paliege, A., Bachmann, S. & Mutig, K. (2019).
Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells.
Journal of the American Society of Nephrology : JASN,
30(6), 946-961.
https://doi.org/10.1681/ASN.2018080816
Kaiser, K., Gyllborg, D., Procházka, J.
, Salašová, A., Kompaníková, P., Molina, F. L., Laguna-Goya, R., Radaszkiewicz, T., Harnoš, J., Procházková, M., Potěšil, D., Barker, R. A., Casado, Á. G., Zdráhal, Z., Sedláček, R., Arenas, E., Villaescusa, J. C. & Bryja, V. (2019).
WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.
Nature Communications,
10(1), Artikel 1498.
https://doi.org/10.1038/s41467-019-09298-4
Johnsen, N., Hamilton, A. D. M., Greve, A. S., Christensen, M. G., Therkildsen, J. R., Wehmöller, J., Skals, M. & Praetorius, H. A. (2019).
α-Haemolysin production, as a single factor, causes fulminant sepsis in a model of Escherichia coli-induced bacteraemia.
Cellular Microbiology,
21(6), Artikel e13017.
https://doi.org/10.1111/cmi.13017
Khammy, M. M., Kim, S., Bentzen, B. H.
, Lee, S., Choi, I.
, Aalkjær, C. & Jepps, T. A. (2018).
4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances Kv7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries.
British Journal of Pharmacology,
175(3), 501-516.
https://doi.org/10.1111/bph.14097
Giambartolomei, C., Liu, J. Z., Zhang, W.
, Hauberg, M., Shi, H., Boocock, J., Pickrell, J., Jaffe, A. E., Pasaniuc, B. & Roussos, P. (2018).
A Bayesian framework for multiple trait colocalization from summary association statistics.
Bioinformatics,
34(15), 2538-2545.
https://doi.org/10.1093/bioinformatics/bty147
Weyer, K., Andersen, P. K., Schmidt, K., Mollet, G., Antignac, C.
, Birn, H., Nielsen, R. & Christensen, E. I. (2018).
Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice.
Kidney International,
93(2), 335-342.
https://doi.org/10.1016/j.kint.2017.07.024
Mohammadnejad, A., Brasch-Andersen, C., Li, W.
, Haagerup, A., Baumbach, J. & Tan, Q. (2018).
A case-only genome-wide association study on gene-sex interaction in allergic rhinitis.
Annals of Allergy, Asthma & Immunology,
121(3), 366-+.
https://doi.org/10.1016/j.anai.2018.07.001
Godoy, L. D., Rossignoli, M. T., Delfino-Pereira, P., Garcia-Cairasco, N. & de Lima Umeoka, E. H. (2018).
A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications.
Frontiers in Behavioral Neuroscience,
12, 127.
https://doi.org/10.3389/fnbeh.2018.00127
Jordan, V. E., Walker, J. A., Beckstrom, T. O., Steely, C. J., McDaniel, C. L., St Romain, C. P., The Baboon Genome Analysis Consortium, Worley, K. C., Phillips-Conroy, J., Jolly, C. J., Rogers, J., Konkel, M. K. & Batzer, M. A. (2018).
A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms.
Mobile DNA,
9(1), Artikel 13.
https://doi.org/10.1186/s13100-018-0118-3
Jan, A., Jansonius, B., Delaidelli, A., Bhanshali, F., An, Y. A.
, Ferreira, N., Smits, L. M., Negri, G. L., Schwamborn, J. C.
, Jensen, P. H., Mackenzie, I. R., Taubert, S. & Sorensen, P. H. (2018).
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
Acta Neuropathologica Communications,
6(1), Artikel 54.
https://doi.org/10.1186/s40478-018-0554-9
Abd El-Maksoud , A. A., H. Abd El-Ghany, I., S. El-Beltagi, H.
, Anankanbil, S., Banerjee, C., Petersen, S. V., Pérez, B. & Guo, Z. (2018).
Adding functionality to milk-based protein: Preparation, and physico-chemical characterization of β-lactoglobulin-phenolic conjugates.
Food Chemistry,
241, 281-289.
https://doi.org/10.1016/j.foodchem.2017.08.101
Poulsen, S. B., Marin De Evsikova, C.
, Murali, S. K., Praetorius, J., Chern, Y.
, Fenton, R. A. & Rieg, T. (2018).
Adenylyl cyclase 6 is required for maintaining acid-base homeostasis.
Clinical Science,
132(16), 1779-1796.
https://doi.org/10.1042/CS20180060