Peer-reviewed publikationer

Peer-reviewed publications

Granau, A. M., Andersen, P. A., Jakobsen, T., Taouxi, K., Dalila, N., Mogensen, J. B., Kristensen, L. S., Grønbæk, K. & Dimopoulos, K. (2023). Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma. Cancers, 15(2), Artikel 510. https://doi.org/10.3390/cancers15020510

Brent, M. B. & Emmanuel, T. (2023). Contemporary Advances in Computer-Assisted Bone Histomorphometry and Identification of Bone Cells in Culture. Calcified Tissue International, 112(1), 1-12. https://doi.org/10.1007/s00223-022-01035-2

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2023). Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement (Journal of Biological Chemistry (2018) 293(17) (6269–6281), (S0021925820397313), (10.1074/jbc.RA117.001179)). The Journal of Biological Chemistry, 299(2), Artikel 102951. https://doi.org/10.1016/j.jbc.2023.102951

Østergaard, M., Naver, E. B., Schüpbach, D., Kaestner, A., Strobl, M., Brüel, A., Thomsen, J. S., Schmidt, S., Poulsen, H. F., Kuhn, L. T. & Birkedal, H. (2023). Correlative study of liquid in human bone by 3D neutron microscopy and lab-based X-ray μCT. Bone, 175, Artikel 116837. https://doi.org/10.1016/j.bone.2023.116837

Ammitzbøll, C., Thomsen, M. K., Andersen, J. B., Bartels, L. E., Hermansen, M.-L. F., Johannsen, A. D., Mistegaard, C. E., Mikkelsen, S., Vils, S. R., Erikstrup, C., Hauge, E.-M. & Troldborg, A. (2023). COVID-19 vaccination in patients with rheumatic diseases leads to a high seroconversion rate and reduced self-imposed isolation and shielding behaviour. Modern Rheumatology, 33(4), 777–785. https://doi.org/10.1093/mr/roac069

Bendixen, L., Jensen, T. I. & Bak, R. O. (2023). CRISPR-Cas-mediated transcriptional modulation: The therapeutic promises of CRISPRa and CRISPRi. Molecular Therapy, 31(7), 1920-1937. https://doi.org/10.1016/j.ymthe.2023.03.024

Berggreen, A. H., Petersen, J. L., Lin, L., Benabdellah, K. & Luo, Y. (2023). CRISPR delivery with extracellular vesicles: Promises and challenges. Journal of Extracellular Biology, 2(9), e111. Artikel e111. https://doi.org/10.1002/jex2.111

Rømer, T. B., Khoder-Agha, F., Aasted, M. K. M., de Haan, N., Horn, S., Dylander, A., Zhang, T., Pallesen, E. M. H., Dabelsteen, S., Wuhrer, M., Høgsbro, C. F., Thomsen, E. A., Mikkelsen, J. G. & Wandall, H. H. (2023). CRISPR-screen identifies ZIP9 and dysregulated Zn2+ homeostasis as a cause of cancer-associated changes in glycosylation. Glycobiology, 33(9), 700-714. https://doi.org/10.1093/glycob/cwad003

Grycel, K., Larsen, N. Y., Feng, Y., Qvortrup, K., Jensen, P. H., Fayyaz, M., Madsen, M. G., Midtgaard, J., Xu, Z., Hasselholt, S. & Nyengaard, J. R. (2023). CRMP2 conditional knockout changes axonal function and ultrastructure of axons in mice corpus callosum. Molecular and Cellular Neuroscience, 126, Artikel 103882. https://doi.org/10.1016/j.mcn.2023.103882

Kanai, R., Vilsen, B., Cornelius, F. & Toyoshima, C. (2023). Crystal structures of Na⁺,K⁺-ATPase reveal the mechanism that converts the K⁺-bound form to Na⁺-bound form and opens and closes the cytoplasmic gate. FEBS Letters, 597(15), 1957-1976. https://doi.org/10.1002/1873-3468.14689

Corydon, T. J., Schulz, H., Richter, P., Strauch, S. M., Böhmer, M., Ricciardi, D. A., Wehland, M., Krüger, M., Erzinger, G. S., Lebert, M., Infanger, M., Wise, P. M. & Grimm, D. (2023). Current Knowledge about the Impact of Microgravity on Gene Regulation. Cells, 12(7), Artikel 1043. https://doi.org/10.3390/cells12071043

Ahle, C. M., Feidenhansl, C. & Brüggemann, H. (2023). Cutibacterium acnes. Trends in Microbiology, 31(4), 419-420. https://doi.org/10.1016/j.tim.2022.10.006

Winther, S., Dupont Rasmussen, L., Westra, J., Abdulzahra, S. R. K., Dahl, J. N., Gormsen, L. C., Christiansen, E. H., Brix, G. S., Mortensen, J., Ejlersen, J. A., Søndergaard, H. M., Hansson, N. C. L., Holm, N. R., Knudsen, L. L., Eftekhari, A., Møller, P. L., Rohde, P. D., Nyegaard, M. & Böttcher, M. (2023). Danish study of Non-Invasive Testing in Coronary Artery Disease 3 (Dan-NICAD 3): Study design of a controlled study on optimal diagnostic strategy. Open Heart, 10(2), Artikel e002328. https://doi.org/10.1136/openhrt-2023-002328

Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J. ... Hansen, T. F. (2023). DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals. BMC genomic data, 24(1), Artikel 30. https://doi.org/10.1186/s12863-023-01132-7

Andersen, C. U., Ahmed, H., Rædkjær, M., Hasselstrøm, J. B. & Larsen, M. K. (2023). Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark. Basic and Clinical Pharmacology and Toxicology, 132(1), 111-119. https://doi.org/10.1111/bcpt.13808

Becker, L. M., Chen, S. H., Rodor, J., de Rooij, L. P. M. H., Baker, A. H. & Carmeliet, P. (2023). Deciphering endothelial heterogeneity in health and disease at single-cell resolution: progress and perspectives. Cardiovascular Research, 119(1), 6-27. https://doi.org/10.1093/cvr/cvac018

Silveira, K. M., Sartim, A. G., Vieira, L., Lisboa, S. F., Wegener, G. & Joca, S. R. L. (2023). Decreased sensitivity to antidepressant drugs in Wistar Hannover rats submitted to two animal models of depression. Acta Neuropsychiatrica, 35(1), 35-49. https://doi.org/10.1017/neu.2022.24

Carrero, J. J., Fu, E. L., Vestergaard, S. V., Jensen, S. K., Gasparini, A., Mahalingasivam, V., Bell, S., Birn, H., Heide-Jørgensen, U., Clase, C. M., Cleary, F., Coresh, J., Dekker, F. W., Gansevoort, R. T., Hemmelgarn, B. R., Jager, K. J., Jafar, T. H., Kovesdy, C. P., Sood, M. M. ... Nitsch, D. (2023). Defining measures of kidney function in observational studies using routine health care data: methodological and reporting considerations. Kidney International, 103(1), 53-69. https://doi.org/10.1016/j.kint.2022.09.020

Davis, F. M. (2023). DEI conversations: more than a box-ticking exercise. Nature Reviews Molecular Cell Biology, 24(4), 238. https://doi.org/10.1038/s41580-022-00565-9

Bordoni, L., Thoren, A. E., Gutiérrez-Jiménez, E., Åbjørsbråten, K. S., Bjørnstad, D. M., Tang, W., Stern, M., Østergaard, L., Nagelhus, E. A., Frische, S., Ottersen, O. P. & Enger, R. (2023). Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema. Glia, 71(11), 2559-2572. https://doi.org/10.1002/glia.24439

Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G. ... Børglum, A. D. (2023). Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. Nature Medicine, 29(7), 1832-1844. https://doi.org/10.1038/s41591-023-02352-1

Philpott, C., Kumaresan, K., Fjaeldstad, A. W., Macchi, A., Monti, G., Frasnelli, J., Konstantinidis, I., Pinto, J., Mullol, J., Boardman, J., Vodicka, J., Holbrook, E., Ramakrishnan, V. R., Lechner, M. & Hummel, T. (2023). Developing a core outcome set for clinical trials in olfactory disorders: a COMET initiative. Rhinology, 61(4), 312-319. https://doi.org/10.4193/Rhin22.116

Sørensen, C. A., Jeffery, L., Falhof, J., Harbig, P., Roelsgaard, K., Gram, S. & Olesen, C. (2023). Developing and piloting a cross-sectoral hospital pharmacist intervention for patients in transition between hospital and general practice. Therapeutic Advances in Drug Safety, 14. https://doi.org/10.1177/20420986231159221

Martinez-Fernandez de la Camara, C., Storm, T., Salman, A., Burgoyne, T., Rasmussen, M. Q., Orlans, H. O., Russell, A. J., Davies, S. G., Barnard, A. R. & MacLaren, R. E. (2023). Developmental Expression of the Cell Cycle Regulator p16^INK4a in Retinal Glial Cells: A Novel Marker for Immature Ocular Astrocytes? Journal of Histochemistry and Cytochemistry, 71(6), 301-320. https://doi.org/10.1369/00221554231184286

Rothemejer, F. H., Lauritsen, N. P., Juhl, A. K., Schleimann, M. H., König, S., Søgaard, O. S., Bak, R. & Tolstrup, M. (2023). Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus. Viruses, 15(1), Artikel 202. https://doi.org/10.3390/v15010202

Melnik, D., Cortés-Sánchez, J. L., Sandt, V., Kahlert, S., Kopp, S., Grimm, D. & Krüger, M. (2023). Dexamethasone Selectively Inhibits Detachment of Metastatic Thyroid Cancer Cells during Random Positioning. Cancers, 15(6), Artikel 1641. https://doi.org/10.3390/cancers15061641

Ravn, K., Hatt, L., Singh, R., Schelde, P., Hansen, E. S., Vogel, I., Uldbjerg, N., Niemann, I. & Sunde, L. (2023). Diagnosis of hydatidiform moles using circulating gestational trophoblasts isolated from maternal blood. Placenta, 135, 7-15. https://doi.org/10.1016/j.placenta.2023.02.012

Isayeva, G., Potlukova, E., Rumora, K., Lopez Ayala, P., Kurun, A., Leibfarth, J.-P., Schäfer, I., Michel, E., Pesen, K., Zellweger, M. J., Trendelenburg, M., Korsgaard Hejlesen, T., Gudmann Hansen, A., Thiel, S. & Mueller, C. (2023). Diagnostic and Prognostic Value of H-ficolin for Functionally Relevant Coronary Artery Disease. Clinica Chimica Acta, 551, Artikel 117582. https://doi.org/10.1016/j.cca.2023.117582

Grimm, P. R., Tatomir, A., Rosenbaek, L. L., Kim, B. Y., Li, D., Delpire, E. J., Fenton, R. A. & Welling, P. A. (2023). Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl co-transporter and reduces blood pressure. Journal of Clinical Investigation, 133(21), Artikel e158498. https://doi.org/10.1172/JCI158498

Jørgensen, C. S., Kamperis, K., Knudsen, J. H., Kjeldsen, M., Christensen, J. H., Borch, L., Rittig, S. & Palmfeldt, J. (2023). Differences in the urinary metabolome and proteome between wet and dry nights in children with monosymptomatic nocturnal enuresis and nocturnal polyuria. Pediatric nephrology (Berlin, Germany), 38(10), 3347-3358. https://doi.org/10.1007/s00467-023-05963-5

Andreasen, M. & Nedergaard, S. (2023). Differential role of oxidative stress in synaptic and nonsynaptic in vitro ictogenesis. Journal of Neurophysiology, 129(5), 999 - 1009. https://doi.org/10.1152/jn.00004.2023

Larsen, M. L., Troldborg, A., Toonen, E. J. M., Hurler, L., Prohaszka, Z., Cervenak, L., Hansen, A. G. & Thiel, S. (2023). Differentiating Between Activation via the Lectin or the Classical Complement Pathway in Patients with Systemic Lupus Erythematosus. Clinical and Experimental Immunology, 214(1), 18-25. https://doi.org/10.1093/cei/uxad070

Mauthe, M., Kampinga, H. H., Hipp, M. S. & Reggiori, F. (2023). Digest it all: the lysosomal turnover of cytoplasmic aggregates. Trends in Biochemical Sciences, 48(3), 216-228. https://doi.org/10.1016/j.tibs.2022.09.012

Jensen, A. M. G., Kitago, Y., Fazeli, E., Vægter, C. B., Small, S. A., Petsko, G. A. & Andersen, O. M. (2023). Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer. Proceedings of the National Academy of Sciences (PNAS), 120(4), Artikel e2212180120. https://doi.org/10.1073/pnas.2212180120

Huang, J., Lin, Q., Fei, H., He, Z., Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zuo, E., Luo, Y., Ran, Y., Qiu, J.-L., Zhao, K. T. & Gao, C. (2023). Discovery of deaminase functions by structure-based protein clustering. Cell, 186(15), 3182-3195.e14. https://doi.org/10.1016/j.cell.2023.05.041

Masaracchia, L., Fredes, F., Woolrich, M. W. & Vidaurre, D. (2023). Dissecting unsupervised learning through hidden Markov modeling in electrophysiological data. Journal of Neurophysiology, 130(2), 364-379. https://doi.org/10.1152/jn.00054.2023

Little, R., Murali, S. K., Poulsen, S. B., Grimm, P. R., Assmus, A., Cheng, L., Ivy, J. R., Hoorn, E. J., Matchkov, V., Welling, P. A. & Fenton, R. A. (2023). Dissociation of sodium-chloride cotransporter expression and blood pressure during chronic high dietary potassium supplementation. JCI Insight, 8(5), Artikel e156437. https://doi.org/10.1172/jci.insight.156437

Munk, D. E., Vendelbo, M. H., Kirk, F. T., Rewitz, K. S., Bender, D. A., Vase, K. H., Munk, O. L., Vilstrup, H., Ott, P. & Sandahl, T. D. (2023). Distribution of non-ceruloplasmin-bound copper after i.v. ⁶⁴Cu injection studied with PET/CT in patients with Wilson disease. JHEP Reports, 5(11), Artikel 100916. https://doi.org/10.1016/j.jhepr.2023.100916

Bering, T., Gadgaard, C., Vorum, H., Honoré, B. & Rath, M. F. (2023). Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. Glia, 71(11), 2623-2641. https://doi.org/10.1002/glia.24443

Møller, P., Seppälä, T. T., Ahadova, A., Crosbie, E. J., Holinski-Feder, E., Scott, R., Haupt, S., Möslein, G., Winship, I., Broeke, S. W. B. T., Kohut, K. E., Ryan, N., Bauerfeind, P., Thomas, L. E., Evans, D. G., Aretz, S., Sijmons, R. H., Half, E., Heinimann, K. ... Dominguez-Valentin, M. (2023). Dominantly inherited micro-satellite instable cancer – the four Lynch syndromes - an EHTG, PLSD position statement. Hereditary Cancer in Clinical Practice, 21(1), Artikel 19. https://doi.org/10.1186/s13053-023-00263-3

Skakkebæk, A., Kjær-Sørensen, K., Matchkov, V. V., Christensen, L. L., Just, J., Cömert, C., Andersen, N. H., Oxvig, C. & Gravholt, C. H. (2023). Dosage of the pseudoautosomal gene SLC25A6 is implicated in QTc interval duration. Scientific Reports, 13(1), Artikel 12089. https://doi.org/10.1038/s41598-023-38867-3

Neldeborg, S., Soerensen, J. F., Møller, C. T., Bill, M., Gao, Z., Bak, R. O., Holm, K., Sorensen, B., Nyegaard, M., Luo, Y., Hokland, P., Stougaard, M., Ludvigsen, M. & Holm, C. K. (2023). Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo. Leukemia, 37(9), 1792-1801. https://doi.org/10.1038/s41375-023-01950-9

Dzamko, N., Romero-Ramos, M. & Thaler, A. (2023). Editorial: Updates on inflammation in Parkinson's disease. Frontiers in Neurology, 14, Artikel 1138543. https://doi.org/10.3389/fneur.2023.1138543

Hendel, A. & Bak, R. O. (2023). Editorial: CRISPR and beyond: Cutting-edge technologies for gene correction in therapeutic applications. Frontiers in Genome Editing, 5, Artikel 1203864. https://doi.org/10.3389/fgeed.2023.1203864

Osório, C., Watt, A. & Kisiswa, L. (2023). Editorial: Molecular mechanisms and pathways in cerebellar function. Frontiers in Molecular Neuroscience, 16, Artikel 1258215. https://doi.org/10.3389/fnmol.2023.1258215

Andreasen, M. & Nedergaard, S. (2023). Effects of carbonic anhydrase activity on the excitability of hippocampal axons during high-frequency firing. Brain Research, 1821, 1-8. Artikel 148604. https://doi.org/10.1016/j.brainres.2023.148604

Jokšienė, J., Sahana, J., Wehland, M., Schulz, H., Cortés-Sánchez, J. L., Prat-Duran, J., Grimm, D. & Simonsen, U. (2023). Effects of High Glucose on Human Endothelial Cells Exposed to Simulated Microgravity. Biomolecules, 13(2), Artikel 189. https://doi.org/10.3390/biom13020189

Díaz-Fernández, A., Ferapontov, A., Vendelbo, M. H. & Ferapontova, E. E. (2023). Electrochemical Cellulase-Linked ELASA for Rapid Liquid Biopsy Testing of Serum HER-2/neu. ACS Measurement Science Au, 3(3), 226-235. https://doi.org/10.1021/acsmeasuresciau.2c00067

Tadini-Buoninsegni, F., Mikkelsen, S., Mogensen, L., Holm, R., Molday, R. S. & Andersen, J. P. (2023). Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4-ATPase ATP8A2. FEBS Letters, 597(4), 495-503. https://doi.org/10.1002/1873-3468.14459

Strandvik, B., Qureshi, A. R., Painer, J., Backman-Johansson, C., Engvall, M., Fröbert, O., Kindberg, J., Stenvinkel, P. & Giroud, S. (2023). Elevated plasma phospholipid n-3 docosapentaenoic acid concentrations during hibernation. PLoS One, 18(6 June), Artikel e0285782. https://doi.org/10.1371/journal.pone.0285782

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Revideret 21.08.2025