Peer-reviewed publikationer

Peer-reviewed publications

Lu, X., Elizondo, R. A., Nielsen, R., Christensen, E. I., Yang, J., Hammock, B. D. & Watsky, M. A. (2015). Vitamin D in Tear Fluid. Investigative Ophthalmology & Visual Science, 56(10), 5880-5887. https://doi.org/10.1167/iovs.15-17177

Telinius, N., Majgaard, J., Kim, S., Katballe, N., Pahle, E., Nielsen, J., Hjortdal, V., Aalkjaer, C. & Bødtkjer, D. M. B. (2015). Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels. The Journal of Physiology, 593(14), 3109-3122. https://doi.org/10.1113/JP270166

Andersen, C. L., Nielsen, H. M., Kristensen, L. S., Søgaard, A., Vikeså, J., Jønson, L., Nielsen, F. C., Hasselbalch, H., Bjerrum, O. W., Punj, V. & Grønbæk, K. (2015). Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome. OncoTarget, 6(38), 40588-97. https://doi.org/10.18632/oncotarget.5845

Qin, H., Samuels, J. F., Wang, Y., Zhu, Y., Grados, M. A., Riddle, M. A., Greenberg, B. D., Knowles, J. A., Fyer, A. J., McCracken, J. T., Murphy, D. L., Rasmussen, S. A., Cullen, B. A., Piacentini, J., Geller, D., Stewart, S. E., Pauls, D., Bienvenu, O. J., Goes, F. S. ... Shugart, Y. Y. (2015). Whole-genome association analysis of treatment response in obsessive-compulsive disorder. Molecular Psychiatry. https://doi.org/10.1038/mp.2015.32

Zheng, H.-F., Forgetta, V., Hsu, Y.-H., Estrada, K., Rosello-Diez, A., Leo, P. J., Dahia, C. L., Park-Min, K. H., Tobias, J. H., Kooperberg, C., Kleinman, A., Styrkarsdottir, U., Liu, C.-T., Uggla, C., Evans, D. S., Nielson, C. M., Walter, K., Pettersson-Kymmer, U., McCarthy, S. ... AOGC Consortium (2015). Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature, 526(7571), 112-7. https://doi.org/10.1038/nature14878

Juraeva, D., Treutlein, J., Scholz, H., Frank, J., Degenhardt, F., Cichon, S., Ridinger, M., Mattheisen, M., Witt, S. H., Lang, M., Sommer, W. H., Hoffmann, P., Herms, S., Wodarz, N., Soyka, M., Zill, P., Maier, W., Jünger, E., Gaebel, W. ... Rietschel, M. (2015). XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set Based Analysis and Follow-up Studies in Drosophila and Humans. Neuropsychopharmacology, 40, 361–371. https://doi.org/10.1038/npp.2014.178

La Rosa, L. R., Perrone, L., Nielsen, M. S., Calissano, P., Andersen, O. M. & Matrone, C. (2015). Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction. Frontiers in Cellular Neuroscience, 9, 109. https://doi.org/10.3389/fncel.2015.00109

Sandow, S. L., Hinkley, V., Lykke-Hartmann, K., Hangaard, L., Staehr, C., Aalkjær, C. & Matchkov, V. (2015). α1-,α2-Na,K-ATPase and Kir 2.1 expression and their implications for cerebral artery function and migraine etiology in a mouse model of Familial Hemiplegic Migraine type 2. Proceedings of the Australian Physiological Society, 46. http://aups.org.au/Proceedings/46/

Roos, J., Oancea, C., Heinssmann, M., Khan, D., Held, H., Kahnt, A. S., Capelo, R., la Buscató, E., Proschak, E., Puccetti, E., Steinhilber, D., Fleming, I., Maier (shared last author), T. & Ruthardt (shared last author), M. (2014). 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell-like Cells in Acute Myeloid Leukemia. Cancer Research, 74(18), 5244-55. https://doi.org/10.1158/0008-5472.CAN-13-3012

de Paoli, F. V., Nielsen, B. D., Rasmussen, F., Deleuran, B. W. & Søndergaard, K. (2014). Abatacept induces clinical improvement in patients with severe systemic sclerosis. Scandinavian Journal of Rheumatology.

Jensen, J. M., Mose, F. H., Kulik, A.-E. O., Bech, J. N., Fenton, R. A. & Pedersen, E. B. (2014). Abnormal urinary excretion of NKCC2 and AQP2 in response to hypertonic saline in chronic kidney disease: an intervention study in patients with chronic kidney disease and healthy controls. B M C Nephrology, 15, 101. https://doi.org/10.1186/1471-2369-15-101

Doktor, T. K., Schrøder, L. D., Andersen, H. S., Brøner, S., Kitewska, A., Sørensen, C. B. & Andresen, B. S. (2014). Absence of an intron splicing silencer in porcine Smn1 intron 7 confers immunity to the exon skipping mutation in human SMN2. PLOS ONE, 9(6), e98841. https://doi.org/10.1371/journal.pone.0098841

Wittenborn, T. R., Larsen, E. K. U., Nielsen, T., Rydtoft, L. M., Hansen, L., Nygaard, J. V., Vorup-Jensen, T., Kjems, J., Horsman, M. R. & Nielsen, N. C. (2014). Accumulation of nano-sized particles in a murine model of angiogenesis. Biochemical and Biophysical Research Communications, 443(2), 470-6. https://doi.org/10.1016/j.bbrc.2013.11.127

Rockenstein, E., Nuber, S., Overk, C. R., Ubhi, K., Mante, M., Patrick, C., Adame, A., Trejo-Morales, M., Gerez, J., Picotti, P., Jensen, P. H., Campioni, S., Riek, R., Winkler, J., Gage, F. H., Winner, B. & Masliah, E. (2014). Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain, 137(Pt 5), 1496-513. https://doi.org/10.1093/brain/awu057

Wang, H., Flannery, S. M., Dickhöfer, S., Huhn, S., George, J., Kubarenko, A. V., Lascorz, J., Bevier, M., Willemsen, J., Pichulik, T., Schafmayer, C., Binder, M., Manoury, B., Paludan, S. R., Alarcon-Riquelme, M., Bowie, A. G., Försti, A. & Weber, A. N. R. (2014). A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival. Journal of Biological Chemistry, 289(33), 23123-31. https://doi.org/10.1074/jbc.M113.492934

Thudium, C. S., Moscatelli, I., Flores, C., Thomsen, J. S., Brüel, A., Gudmann, N. S., Hauge, E. M., Karsdal, M. A., Richter, J. & Henriksen, K. (2014). A comparison of osteoclast-rich and osteoclast-poor osteopetrosis in adult mice sheds light on the role of the osteoclast in coupling bone resorption and bone formation. Calcified Tissue International, 95(1), 83-93. https://doi.org/10.1007/s00223-014-9865-4

Hasenfuss, S. C., Bakiri, L., Thomsen, M. K., Hamacher, R. & Wagner, E. F. (2014). Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism. Hepatology, 59(1), 261-73. https://doi.org/10.1002/hep.26518

Vildbrad, M. D., Andersen, A., Holmboe, S., Ringgaard, S., Nielsen, J. M. & Nielsen-Kudsk, J. E. (2014). Acute effects of levosimendan in experimental models of right ventricular hypertrophy and failure. Pulmonary Circulation, 4(3), 511-519. https://doi.org/10.1086/677366

Vegger, J. B., Nielsen, E. S., Brüel, A. & Thomsen, J. S. (2014). Additive effect of PTH (1-34) and zoledronate in the prevention of disuse osteopenia in rats. Bone, 66, 287-295. https://doi.org/10.1016/j.bone.2014.06.020

Dybkaer, K., Bogsted, M., Falgreen, S., Kjeldsen, M. K., Schmitz, A., Bodker, J. S., Bilgrau, A. E., Xu-Monette, Z. Y., Ling, L., Bergkvist, K. S., Laursen, M. B., Rodrigo-Domingo, M., Marques, S. C., Rasmussen, S. B., Nyegaard, M., Gaihede, M., Moller, M. B., Samworth, R., Shah, R. ... Johnsen, H. E. (2014). A Diffuse Large B-Cell Lymphoma Classification System That Associates Normal B-Cell Subset Phenotypes with Prognosis. Poster-session præsenteret på 56th Annual Meeting of the American-Society-of-Hematology , USA.

Strauss, S., Greve, T., Ernst, E., Fraidakis, M., Grudzinskas, J. G. & Andersen, C. Y. (2014). Administration of DHEA augments progesterone production in a woman with low ovarian reserve being transplanted with cryopreserved ovarian tissue. Journal of Assisted Reproduction and Genetics, 31(6), 645-9. https://doi.org/10.1007/s10815-014-0214-3

Nielsen, M. H., Beck-Nielsen, H., Andersen, M. N. & Handberg, A. (2014). A flow cytometric method for characterization of circulating cell-derived microparticles in plasma. Journal of Extracellular Vesicles, 3. https://doi.org/10.3402/jev.v3.20795

Torekov, S., Harsløf, T., Rejnmark, L., Eiken, P. A., Jensen, JB., Hansen, T., Pedersen, O., Hermann, AP., Holst, JJ. & Langdahl, B. L. (2014). A Functional Amino Acid Substitution in the Glucose-dependent Insulinotropic Polypeptide-Receptor (GIPR) Gene is Associated with Lower Bone Mineral Density and Increased Fracture risk. Journal of Clinical Endocrinology and Metabolism, jc20133766. https://doi.org/10.1210/jc.2013-3766

Oei, L., Hsu, Y.-H., Styrkarsdottir, U., Eussen, B. H., de Klein, A., Peters, M. J., Halldorsson, B., Liu, C.-T., Alonso, N., Kaptoge, S. K., Thorleifsson, G., Hallmans, G., Hocking, L. J., Husted, L. B., Jameson, K. A., Kruk, M., Lewis, J. R., Patel, M. S., Scollen, S. ... Estrada, K. (2014). A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Journal of Medical Genetics, 51(2), 122-31. https://doi.org/10.1136/jmedgenet-2013-102064

Kim, V., Desai, P., Newell, J. D., Make, B. J., Washko, G. R., Silverman, E. K., Crapo, J. D., Bhatt, S. P., Criner, G. J., COPDGene Investigators & Mattheisen, M. (2014). Airway wall thickness is increased in COPD patients with bronchodilator responsiveness. Respiratory Research Review, 15, 84. https://doi.org/10.1186/s12931-014-0084-3

Joergensen, M. W., Agerholm, I., Hindkjaer, J., Bolund, L., Sunde, L., Ingerslev, H. J. & Kirkegaard, K. (2014). Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method: A time-lapse study. Journal of Assisted Reproduction and Genetics. https://doi.org/10.1007/s10815-014-0178-3

Damsgaard Gunst, J., Klostergaard, K. R. & Leutscher, P. D. C. (2014). Ambulant neuropsykologisk opfølgning af patienter indlagt med aseptisk meningitis. Ugeskrift for Læger, 176(43).

Jørgensen, N. P., Meyer, R., Dagnæs-Hansen, F., Fuursted, K. & Petersen, E. (2014). A modified chronic infection model for testing treatment of Staphylococcus aureus biofilms on implants. PLOS ONE, 9(10), Artikel e103688. https://doi.org/10.1371/journal.pone.0118124

Jørgensen Cehofski, L., Mandal, N., Honoré, B. & Vorum, H. (2014). Analytical platforms in vitreoretinal proteomics. Bioanalysis, 6, 3051-3066. https://doi.org/10.4155/BIO.14.227

Dahl, L. D., Corydon, T. J., Ränkel, L., Nielsen, K. M., Füchtbauer, E.-M. & Knudsen, C. R. (2014). An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus. Cancer Cell International, 14(17), 1-11. https://doi.org/10.1186/1475-2867-14-17

Cecchi, C. R., Dagnæs-Hansen, F., Aagaard, L., Jakobsen, M. V., Gissel, H., Gothelf, A. B. V., Hansen, B. H., Frystyk, J., Higuti, E., Oliveira, N. A. J., Lima, E. R., Bartolini, P., Jensen, T. G. & Peroni, C. N. (2014). An homologous model of gene therapy by in vivoadministration of a plasmid containing the mouse growth hormone gene in immunocompetentdwarf mice. Poster-session præsenteret på Annual Congress of the European Society of Gene and Cell Therapy, Versailles, Frankrig.

Laska, M. J., Hansen, B., Troldborg, A., Lorenzen, T., Stengaard-Pedersen, K., Junker, P., Nexø, B. A. & Lindegaard, H. M. (2014). A non-synonymous single-nucleotide polymorphism in the gene encoding Toll-like Receptor 3 (TLR3) is associated with sero-negative Rheumatoid Arthritis (RA) in a Danish population. BMC Research Notes, 7(1), 716. https://doi.org/10.1186/1756-0500-7-716

Scholz, C. F. P., Jensen, A., Lomholt, H. B., Brüggemann, H. & Kilian, M. (2014). A Novel High-Resolution Single Locus Sequence Typing Scheme for Mixed Populations of Propionibacterium acnes In Vivo. PLOS ONE, 9(8), e104199. https://doi.org/10.1371/journal.pone.0104199

Cecchi, C. R., Higuti, E., Oliveira, N. A. J., Lima, E. R., Jakobsen, M., Dagnaes-Hansen, F., Gissel, H., Aagaard, L., Jensen, T. G., Jorge, A. A. L., Bartolini, P. & Peroni, C. N. (2014). A novel homologous model for gene therapy of dwarfism by non-viral transfer of the mouse growth hormone gene into immunocompetent dwarf mice. Current Gene Therapy, 14(1), 44-51.

Nielsen, O. H., Grimm, D., Wehland, M., Bauer, J. & Magnusson, N. E. (2014). Anti-Angiogenic Drugs in the Treatment of Metastatic Renal Cell Carcinoma:Advances in Clinical Application. Current Vascular Pharmacology, 13(3), 381-391.

Kristensen, T. B., Knutsson, M. L. T., Wehland, M., Laursen, B. E., Grimm, D. G., Warnke, E. & Magnusson, N. E. (2014). Anti-Vascular Endothelial Growth Factor Therapy in Breast Cancer. International Journal of Molecular Sciences (Online), 15(12), 23024-23041. https://doi.org/10.3390/ijms151223024

Assentoft, M., Larsen, B. R., Olesen, E. T. B., Fenton, R. A. & MacAulay, N. (2014). AQP4 plasma membrane trafficking or channel gating is not significantly modulated by phosphorylation at C-terminal serine residues. A J P: Cell Physiology (Online), ajpcell.00182.2014. https://doi.org/10.1152/ajpcell.00182.2014

Hansen, M. R., Lander, F., Skjold, T., Kolstad, H. A., Hoffmann, H. J. & Schlünssen, V. (2014). Arbejdsbetinget astma udløst af maleinsyreanhydrid. Ugeskrift for Læger, 176(37). https://ugeskriftet.dk/videnskab/arbejdsbetinget-astma-udlost-af-maleinsyreanhydrid

Kjær, T. R. & Thiel, S. (2014). Assay for estimation of the functional activity of the mannan-binding lectin pathway of the complement system. I M. Gadjeva (red.), The Complement System : Methods and Protocols (s. 131-139). Springer. https://doi.org/10.1007/978-1-62703-724-2_11

Pujolar, J. M., Jacobsen, L. M. W., Als, T. D., Frydenberg, J., Magnussen, E., Jonsson, B., Jiang, X., Cheng, L., Bekkevold, D., Maes, G. E., Bernatchez, L. & Hansen, M. M. (2014). Assessing patterns of hybridization between North Atlantic eels using diagnostic single nucleotide polymorphisms. Heredity, 112, 627-637. https://doi.org/10.1038/hdy.2013.145

Holt, C. B., Thiel, S., Munk, K., Østergaard, J. A., Bøtker, H. E. & Hansen, T. K. (2014). Association between endogenous complement inhibitor and myocardial salvage in patients with myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 3(1), 3-9. https://doi.org/10.1177/2048872613507004

Bouzinova, E., Bødtkjer, D. M. B., Kudryavtseva, O., Wiborg, O., Aalkjær, C. & Matchkov, V. (2014). Association between endothelial dysfunction and depression-like symptoms in chronic mild stress model of depression. Psychosomatic Medicine, 76(4), 268-76.

Østergaard, J. A., Thiel, S., Hovind, P., Holt, C. B., Parving, H.-H., Flyvbjerg, A., Rossing, P. & Hansen, T. K. (2014). Association of the pattern recognition molecule H-ficolin with incident microalbuminuria in an inception cohort of newly diagnosed type 1 diabetic patients: an 18 year follow-up study. Diabetologia, 57(10), 2201-7. https://doi.org/10.1007/s00125-014-3332-7

Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. S., van der Most, P. J., Pasko, D., Zgaga, L. ... LifeLines Cohort Study investigators (2014). Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The Lancet Diabetes & Endocrinology, 2(9), 719-29. https://doi.org/10.1016/S2213-8587(14)70113-5

Bank, S., Andersen, P. S., Burisch, J., Pedersen, N., Roug, S., Galsgaard, J., Turino, S. Y., Brodersen, J. B., Rashid, S., Rasmussen, B. K., Avlund, S., Olesen, T. B., Hoffmann, H. J., Thomsen, M. K., Thomsen, V. Ø., Frydenberg, M., Nexø, B. A., Sode, J., Vogel, U. & Andersen, V. (2014). Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. Pharmacogenomics Journal, 526–534. https://doi.org/10.1038/tpj.2014.19

Jensen, M. G., Rungby, J., Brock, B. & Gjedde, A. (2014). At the centennial of Michaelis and Menten, competing Michaelis-Menten steps explain effect of GLP-1 on blood-brain transfer and metabolism of glucose. Basic & Clinical Pharmacology & Toxicology, 115(2), 162-171. https://doi.org/10.1111/bcpt.12240

Bech, A. Z. & Herlin, T. (2014). Autoinflammatoriske knoglesygdomme hos børn. Ugeskrift for Læger, 176(31).

Skals, M., Bjaelde, R. G., Reinholdt, J., Poulsen, K., Vad, B. S., Otzen, D., Leipziger, J. & Praetorius, H. A. (2014). Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore. Journal of Biological Chemistry, 289, 19098-19109. https://doi.org/10.1074/jbc.M114.571414

Licht, R. W. & Straszek, S. P. V. (2014). Behandling af mani hos voksne (Treatment of mania in adults). Ugeskrift for Læger, 176(7).

McDonald, M.-L. N., Mattheisen, M., Cho, M. H., Liu, Y.-Y., Harshfield, B., Hersh, C. P., Bakke, P., Gulsvik, A., Lange, C., Beaty, T. H. & Silverman, E. K. (2014). Beyond GWAS in COPD: Probing the Landscape between Gene-Set Associations, Genome-Wide Associations and Protein-Protein Interaction Networks. Human Heredity, 78(3), 131-139. https://doi.org/10.1159/000365589

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Revideret 14.09.2020