Peer-reviewed publikationer

Peer-reviewed publications

Yang, C., Gao, S., Dagnæs-Hansen, F., Jakobsen, M. & Kjems, J. (2017). Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo. A C S Applied Materials and Interfaces, 9(14), 12203-12216. https://doi.org/10.1021/acsami.6b16556

Nielsen, S. S. E., Siupka, P., Georgian, A., Preston, J. E., Tóth, A. E., Yusof, S. R., Abbott, N. J. & Nielsen, M. S. (2017). Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells. Journal of Visualized Experiments, 2017(127), Artikel e56277. https://doi.org/10.3791/56277

Hollensen, A. K., Thomsen, R., Bak, R. O., Petersen, C. C., Ermegaard, E. R., Aagaard, L., Damgaard, C. K. & Mikkelsen, J. G. (2017). Improved microRNA suppression by WPRE-linked Tough Decoy microRNA sponges. RNA, 23(8), 1247-1258. https://doi.org/10.1261/rna.061192.117

Niu, D., Wei, H.-J., Lin, L., George, H., Wang, T., Lee, I.-H., Zhao, H.-Y., Kan, Y., Shrock, E., Lesha, E., Wang, G., Luo, Y., Qing, Y., Jiao, D., Zhao, H., Zhou, X., Wang, S., Wei, H., Güell, M. ... Yang, L. (2017). Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9. Science, 357(6357), 1303-1307. https://doi.org/10.1126/science.aan4187

Ogunjimi, B., Zhang, S.-Y., Sørensen, K. B., Skipper, K. A., Carter-Timofte, M., Kerner, G., Luecke, S., Prabakaran, T., Cai, Y., Meester, J., Bartholomeus, E., Bolar, N. A., Vandeweyer, G., Claes, C., Sillis, Y., Lorenzo, L., Fiorenza, R. A., Boucherit, S., Dielman, C. ... Mogensen, T. H. (2017). Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections. Journal of Clinical Investigation, 127(9), 3543-3556. https://doi.org/10.1172/JCI92280

Jørgensen, L. K., Dalgaard, L. S., Østergaard, L. J., Nørgaard, M. & Mogensen, T. H. (2017). Incidence and Mortality of Herpes Simplex Encephalitis in Denmark: a nationwide registry-based cohort study. The Journal of infection, 74(1), 42-49. https://doi.org/10.1016/j.jinf.2016.09.004

Møller, P., Seppälä, T., Bernstein, I., Holinski-Feder, E., Sala, P., Evans, D. G., Lindblom, A., Macrae, F., Blanco, I., Sijmons, R., Jeffries, J., Vasen, H., Burn, J., Nakken, S., Hovig, E., Rødland, E. A., Tharmaratnam, K., de Vos Tot Nederveen Cappel, W. H., Hill, J. ... Mallorca Group (http://mallorca-group.org) (2017). Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database. Gut, 66(9), 1657-1664. https://doi.org/10.1136/gutjnl-2016-311403

Ostergaard, J. A., Thiel, S., Hoffmann-Petersen, I. T., Hovind, P., Parving, H.-H., Tarnow, L., Rossing, P. & Hansen, T. K. (2017). Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes. Diabetes/Metabolism Research and Reviews, 33(5), Artikel e2895 . https://doi.org/10.1002/dmrr.2895

Kragstrup, T. W., Andersen, M. N., Schiøttz-Christensen, B., Jurik, A. G., Hvid, M. & Deleuran, B. (2017). Increased IL-20 and IL-24 target osteoblasts and synovial monocytes in spondyloarthritis. Clinical and Experimental Immunology, 189(3), 342-351. https://doi.org/10.1111/cei.12973

Meier, S., Mattheisen, M., Mors, O., Mortensen, P. B., Munk, T. & Penninx, B. (2017). INCREASED MORTALITY AMONG PERSONS WITH ANXIETY DISORDERS AND DEPRESSION: A TOTAL POPULATION STUDY. European Neuropsychopharmacology, 27, S267-S267.

Ng, F. L., Boedtkjer, E., Witkowska, K., Ren, M., Zhang, R., Tucker, A., Aalkjær, C., Caulfield, M. J. & Ye, S. (2017). Increased NBCn1 expression, Na⁺/HCO₃^– co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension. Human Molecular Genetics, 26(5), 989-1002. Artikel ddx015. https://doi.org/10.1093/hmg/ddx015

Demuth, C., Andersen, M. N., Jakobsen, K. R., Madsen, A. T. & Sørensen, B. S. (2017). Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment. OncoTarget, 8(40), 68221-68229. https://doi.org/10.18632/oncotarget.19920

Toustrup, L. B., Zhou, Y., Kvistgaard, H., Gregersen, N., Rittig, S., Aagaard, L., Corydon, T. J., Luo, Y. & Christensen, J. H. (2017). Induced pluripotent stem cells derived from a patient with autosomal dominant familial neurohypophyseal diabetes insipidus caused by a variant in the AVP gene. Stem Cell Research, 19, 37-42. https://doi.org/10.1016/j.scr.2016.12.021

Rasmussen, M., Sunde, L., Andersen, R. F., Petersen, O. B., Olsen, M. S. & Danish Fetal Medicine Research Group (2017). Infants with prenatally diagnosed kidney anomalies have an increased risk of urinary tract infections. Acta paediatrica (Oslo, Norway : 1992), 106(11), 1875-1881. https://doi.org/10.1111/apa.14014

Frøling, M., Mikkelsen, C., Eggertsen, P. P., Stern, M., van de Looij, A. & Deleuran, B. (2017). Inhibition of the Janus kinase-signal transducer and activator of transcription is a new treatment modality of rheumatoid arthritis. Ugeskrift for Læger, 179(44).

Sehgal, P., Szalai, P., Olesen, C., Praetorius, H. A., Nissen, P., Christensen, S. B., Engedal, N. & Møller, J. V. (2017). Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response. Journal of Biological Chemistry, 292(48), 19656-19673. https://doi.org/10.1074/jbc.M117.796920

Rasmussen, D. K., Glerup Lauridsen, K., Staerk, M., Mygind-Klausen, T. & Loefgren, B. (2017). In-Hospital Basic Life Support: Major Differences in Duration, Retraining Intervals, and Training Methods - A Danish Nationwide Study. Circulation, 136(Suppl 1), A20392. http://circ.ahajournals.org/content/136/Suppl_1/A20392.abstract

Halling Folkmar Andersen, A. (2017). Injectable albumin conjugated polymers: a novel drug delivery platform with long blood residence time and retained pharmacological activity. Abstract fra GSK-CRS Long-acting injectable and implantables conference, Philadelphia, Pennsylvania, USA.

Wolley, M. J., Wu, A., Xu, S., Gordon, R. D., Fenton, R. A. & Stowasser, M. (2017). In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance. Journal of the American Society of Nephrology, 28(1), 56-63. https://doi.org/10.1681/ASN.2015111221

Pakula, M. M., Maier, T. J. & Vorup-Jensen, T. (2017). Insight on the impacts of free amino acids and their metabolites on the immune system from a perspective of inborn errors of amino acid metabolism. Expert Opinion On Therapeutic Targets, 21(6), 611-626. https://doi.org/10.1080/14728222.2017.1323879

Larsen, C. K., Praetorius, H. A., Leipziger, J. & Sorensen, M. V. (2017). Intact colonic KCa1.1 channel activity in KCNMB2 knockout mice. Physiological Reports, 5(5), Artikel e13179. https://doi.org/10.14814/phy2.13179

Suppli, N. P., Agerbo, E., Andersen, K. K., Rajagopal, V. M., Benros, M., Thompson, W. K., Mors, O., Munk-Olsen, T., Nordentoft, M., Mortensen, P. B. & Musliner, K. (2017). Interaction of genetic risk and early life stress on risk for depression investigated in a nationwide, Danish case-cohort study. Abstract fra World Congress of Psychiatric Genetics , Orlando, Florida, USA.

Nyvad, J., Mazur, A., Postnov, D. D., Straarup, M. S., Soendergaard, A. M., Staehr, C., Brøndum, E., Aalkjaer, C. & Matchkov, V. V. (2017). Intravital investigation of rat mesenteric small artery tone and blood flow. The Journal of Physiology, 595(15), 5037-5053. https://doi.org/10.1113/JP274604

Damgaard, C., Reinholdt, J., Palarasah, Y., Enevold, C., Nielsen, C., Brimnes, M. K., Holmstrup, P. & Nielsen, C. H. (2017). In vitro complement activation, adherence to red blood cells and induction of mononuclear cell cytokine production by four strains of Aggregatibacter actinomycetemcomitans with different fimbriation and expression of leukotoxin. Journal of Periodontal Research, 52(3), 485-496. https://doi.org/10.1111/jre.12414

Holmgaard, A., Askou, A. L., Benckendorff, J. N. E., Thomsen, E. A., Cai, Y., Bek, T., Mikkelsen, J. G. & Corydon, T. J. (2017). In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells. Molecular Therapy - Nucleic Acids, 9, 89-99. https://doi.org/10.1016/j.omtn.2017.08.016

Chen, F., Liu, P., Gu, Y., Zhu, Z., Nanisetti, A., Lan, Z., Huang, Z., Liu, J. S., Kang, X., Deng, Y., Luo, L., Jiang, D., Qiu, Y., Pan, J., Xia, J., Xiong, K., Liu, C., Xie, L., Shi, Q. ... Xu, X. (2017). Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non-invasive prenatal testing. Prenatal Diagnosis, 37(13), 1311-1321. https://doi.org/10.1002/pd.5186

Dann, G. P., Liszczak, G. P., Bagert, J. D., Müller, M. M., Nguyen, U. T. T., Wojcik, F., Brown, Z. Z., Bos, J., Panchenko, T., Pihl, R., Pollock, S. B., Diehl, K. L., Allis, C. D. & Muir, T. W. (2017). ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature, 548(7669), 607-611. https://doi.org/10.1038/nature23671

Thorup, L., Simonsen, U., Grimm, D. & Hedegaard, E. R. (2017). Ivabradine: Current and Future Treatment of Heart Failure. Basic & Clinical Pharmacology & Toxicology, 121(2), 89-97. https://doi.org/10.1111/bcpt.12784

Gormsen, L. C., Svart, M., Thomsen, H. H., Søndergaard, E., Vendelbo, M., Christensen, N. L., Tolbod, L. P., Harms, H. J., Nielsen, R., Wiggers, H., Jessen, N., Hansen, J., Bøtker, H. E. & Møller, N. (2017). Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study. Journal of the American Heart Association, 6(3), 1-11. Artikel e005066. https://doi.org/10.1161/JAHA.116.005066

Andrukhova, O., Bayer, J., Schüler, C., Zeitz, U., Murali, S. K., Ada, S., Alvarez-Pez, J. M., Smorodchenko, A. & Erben, R. G. (2017). Klotho Lacks an FGF23-Independent Role in Mineral Homeostasis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 32(10), 2049-2061. https://doi.org/10.1002/jbmr.3195

Raaby, L., Rosada, C., Langkilde, A., Lauridsen, K. L., Vinter, H., Andersen, P. O., Kjellerup, R. B., Johansen, C. & Iversen, L. (2017). Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment. Experimental Dermatology, 804-810. Artikel 26(9). https://doi.org/10.1111/exd.13304

Hauberg, M. E., Zhang, W., Giambartolomei, C., Franzen, O., Morris, D. L., Vyse, T. J., Ruusalepp, A., Sklar, P., Schadt, E. E., Bjorkegren, J. L. M., Roussos, P. & CommonMind Consortium (2017). Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression. American Journal of Human Genetics, 100(6), 885-894. https://doi.org/10.1016/j.ajhg.2017.04.016

Jendroszek, A., Sønnichsen, M., Chana Munoz, A., Leyman, K., Christensen, A., Petersen, S. V., Bendixen, C., Panitz, F., Andreasen, P. & Jensen, J. K. (2017). Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved. Thrombosis and Haemostasis, 117(9), 1688-1699. https://doi.org/10.1160/TH17-02-0102

Medjeral-Thomas, N. R., Troldborg, A., Lomax-Browne, H., Willicombe, M., Cook, H. T., Thiel, S. & Pickering, M. C. (2017). Lectin Complement Pathway Plasma Levels in IgA Nephropathy. Molecular Immunology SI: EMCHD2017 Vol 89 2017..

Troldborg, A., Hansen, A. G., Hansen, S. W. K., Jensenius, J. C., Stengaard-Pedersen, K. & Thiel, S. (2017). Lectin Complement Pathway Proteins in Healthy Individuals. Clinical and Experimental Immunology, 188(1), 138–147 . https://doi.org/10.1111/cei.12909

Troldborg, A., Thiel, S., Trendelenburg, M., Friebus-Kardash, J., Nehring, J., Steffensen, R., Hansen, S. W. K., Laska, M. J., Deleuran, B. W., Jensenius, J. C., Voss, A. & Stengaard-Pedersen, K. (2017). Lectin Pathway Proteins and association to Systemic Lupus Erythematosus.Troldborg. Molecular Immunology SI: EMCHD2017 Vol 89 2017..

Stjernholm, T., Andersen, P. O., Nielsen, A. L.-L., Johansen, C., Iversen, L., Kjeldsen, C. R. & Stenderup, K. (2017). Leptin-deficiency in ob/ob mice counteracts imiquimod (IMQ)-induced psoriasis-like skin inflammation while leptin induces a psoriatic phenotype in human keratinocytes. Experimental Dermatology, 338-345. Artikel 26(4).