Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Rowitch, D. H., Hurles, M. E., Geschwind, D. H.
, Børglum, A. D., Robinson, E. B.
, Grove, J., Martin, H. C., Bourgeron, T., Baron-Cohen, S., EU-AIMS LEAP ... Spectrum 10K and APEX Consortia (2022).
Genetic correlates of phenotypic heterogeneity in autism.
Nature Genetics,
54(9), 1293-1304.
https://doi.org/10.1038/s41588-022-01072-5
Petrillo, F., Chernyakov, D.
, Esteva Font, C., Poulsen, S. B., Edemir, B.
& Fenton, R. A. (2022).
Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus.
FASEB Journal,
36(11), Artikel e22583.
https://doi.org/10.1096/fj.202200856R
Eising, E., Mirza-Schreiber, N., de Zeeuw, E. L., Wang, C. A., Truong, D. T., Allegrini, A. G., Shapland, C. Y., Zhu, G., Wigg, K. G., Gerritse, M. L., Molz, B., Alagoz, G., Gialluisi, A., Abbondanza, F., Rimfeld, K., van Donkelaar, M., Liao, Z., Jansen, P. R., Andlauer, T. F. M. ... Fisher, S. E. (2022).
Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.
Proceedings of the National Academy of Sciences,
119(35), Artikel e2202764119.
https://doi.org/10.1073/pnas.2202764119
Karlsson, M., Sjöstedt, E., Oksvold, P., Sivertsson, Å.
, Huang, J., Álvez, M. B., Arif, M., Li, X.
, Lin, L., Yu, J., Ma, T., Xu, F., Han, P., Jiang, H., Mardinoglu, A., Zhang, C., von Feilitzen, K., Xu, X., Wang, J. ... Uhlen, M. (2022).
Genome-wide annotation of protein-coding genes in pig.
BMC Biology,
20, Artikel 25.
https://doi.org/10.1186/s12915-022-01229-y
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K.
, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F.
, Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V.
, Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022).
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes.
Brain : a journal of neurology,
145(2), 555–568.
https://doi.org/10.1093/brain/awab260
Suppli, N. P., Andersen, K. K.
, Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E.
, Als, T. D., Grove, J., Werge, T.
, Børglum, A. D., Hougaard, D. M.
... Musliner, K. L. (2022).
Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample.
Biological Psychiatry: Global Open Science,
2(4), 400-410.
https://doi.org/10.1016/j.bpsgos.2021.11.003
Vershkov, D., Yilmaz, A., Yanuka, O.
, Nielsen, A. L. & Benvenisty, N. (2022).
Genome-wide screening for genes involved in the epigenetic basis of fragile X syndrome.
Stem Cell Reports,
17(5), 1048-1058.
https://doi.org/10.1016/j.stemcr.2022.03.011
Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A.
, Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Mors, O. ... Bønnelykke, K. (2022).
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
Journal of Allergy and Clinical Immunology,
150(3), 622-630.
https://doi.org/10.1016/j.jaci.2022.03.019
Seeler, S., Moldovan, L.-I., Bertelsen, T., Hager, H., Iversen, L., Johansen, C., Kjems, J. & Sommer Kristensen, L. (2022).
Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment.
PLOS ONE,
17(9), Artikel e0275219.
https://doi.org/10.1371/journal.pone.0275219
Monti, G., Gomes Moreira, D.
, Richner, M., Mutsaers, H. A. M., Ferreira, N. & Jan, A. (2022).
GLP-1-Receptor Agonists in Neurodegeneration: Neurovascular Unit in the Spotlight.
Cells,
11(13), Artikel 2023.
https://doi.org/10.3390/cells11132023
Farzadfard, A., König, A.
, Petersen, S. V., Nielsen, J., Vasili, E., Dominguez-Meijide, A., Buell, A. K., Outeiro, T. F.
& Otzen, D. E. (2022).
Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition.
The Journal of Biological Chemistry,
298(5), Artikel 101848.
https://doi.org/10.1016/j.jbc.2022.101848
Skytthe, M. K., Sørensen, A. L., Hennig, D., Sandberg, M. B.
, Rasmussen, L. M., Højrup, P.
, Møller, H. J., Skjødt, K.
, Moestrup, S. K. & Graversen, J. H. (2022).
Haptoglobin-related protein in human plasma correlates to haptoglobin concentrations and phenotypes.
Scandinavian Journal of Clinical and Laboratory Investigation,
82(6), 461-466.
https://doi.org/10.1080/00365513.2022.2122076
Dall, L. B., Deleuran, B., Østergaard, L. J., Mardahl, M., Denton, P. W.
& Nejsum, P. (2022).
Helminth products modulate innate immune recognition of nucleic acids in systemic lupus erythematosus.
Lupus,
31(4), 415-423.
https://doi.org/10.1177/09612033221080548
Vohwinkel, C. U., Burns, N., Coit, E., Yuan, X., Vladar, E. K., Sul, C., Schmidt, E. P.
, Carmeliet, P., Stenmark, K., Nozik, E. S., Tuder, R. M. & Eltzschig, H. K. (2022).
HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury.
JCI Insight,
7(24), Artikel e157855.
https://doi.org/10.1172/jci.insight.157855
Brandt, C. B., Fonager, S. V., Haskó, J., Helmig, R. B., Degn, S., Bolund, L., Jessen, N., Lin, L. & Luo, Y. (2022).
HIF1A Knockout by Biallelic and Selection-Free CRISPR Gene Editing in Human Primary Endothelial Cells with Ribonucleoprotein Complexes.
Biomolecules,
13(1), Artikel 23.
https://doi.org/10.3390/biom13010023
Yiu, G.
, Rasmussen, T. K., Tsai, B. L., Diep, V. K., Haddon, D. J., Tsoi, J., Miller, G. D., Comin-Anduix, B.
, Deleuran, B., Crooks, G. M. & Utz, P. J. (2022).
High Interferon Signature Leads to Increased STAT1/3/5 Phosphorylation in PBMCs From SLE Patients by Single Cell Mass Cytometry.
Frontiers in Immunology,
13, Artikel 833636.
https://doi.org/10.3389/fimmu.2022.833636
Laursen, T. L., Bossen, L., Pihl, R., Troldborg, A., Sandahl, T. D., Hansen, A. G., Folserass, T., Vesterhus, M.
, Gronbaek, H. & Thiel, S. (2022).
Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4 (ITIH4) in Autoimmune Cholestatic Liver Diseases.
Journal of clinical and translational hepatology,
10(5), 796–802.
https://doi.org/10.14218/JCTH.2021.00515
Watson, H. R., Duong, V., Ly, S., Mandron, M., Siqueira, A. M. & Ribeiro, G. S. (2022).
Household clustering supports a novel chemoprophylaxis trial design for a mosquito-borne viral disease.
International Journal of Infectious Diseases,
122, 169-173.
https://doi.org/10.1016/j.ijid.2022.05.020
Cen, H. H., Hussein, B., Botezelli, J. D., Wang, S., Zhang, J. A., Noursadeghi, N.
, Jessen, N., Rodrigues, B., Timmons, J. A. & Johnson, J. D. (2022).
Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance.
The FASEB Journal,
36(1), Artikel e22088.
https://doi.org/10.1096/fj.202100497RR
Peng, R., Wang, C. K., Wang-Kan, X.
, Idorn, M., Kjær, M., Zhou, F. Y., Fiil, B. K., Timmermann, F., Orozco, S. L., McCarthy, J., Leung, C. S., Lu, X., Bagola, K., Rehwinkel, J., Oberst, A., Maelfait, J.
, Paludan, S. R. & Gyrd-Hansen, M. (2022).
Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.
EMBO Reports,
23(12), Artikel e55839.
https://doi.org/10.15252/embr.202255839
Brent, M. B., Emmanuel, T., Simonsen, U., Brüel, A. & Thomsen, J. S. (2022).
Hypobaric hypoxia deteriorates bone mass and strength in mice.
Bone,
154, Artikel 116203.
https://doi.org/10.1016/j.bone.2021.116203
Egstrand, S., Mace, M. L., Morevati, M., Nordholm, A., Engelholm, L. H.
, Thomsen, J. S., Brüel, A., Naveh-Many, T., Guo, Y., Olgaard, K. & Lewin, E. (2022).
Hypomorphic expression of parathyroid Bmal1 disrupts the internal parathyroid circadian clock and increases parathyroid cell proliferation in response to uremia.
Kidney International,
101(6), 1232-1250.
https://doi.org/10.1016/j.kint.2022.02.018
Maccio, U., Mihic, A., Lenggenhager, D., Kolm, I., Mittmann, C., Heikenwälder, M.
, Lorentzen, A. & Mihic-Probst, D. (2022).
Hypoxia and Ezrin Expression in Primary Melanoma Have High Prognostic Relevance.
International Journal of Molecular Sciences ,
23(18), Artikel 10745.
https://doi.org/10.3390/ijms231810745
Taha, Z., Arulanandam, R., Maznyi, G., Godbout, E.
, Carter-Timofte, M. E., Kurmasheva, N., Reinert, L. S., Chen, A., Crupi, M. J. F., Boulton, S., Laroche, G., Phan, A., Rezaei, R., Alluqmani, N., Jirovec, A., Acal, A., Brown, E. E. F., Singaravelu, R., Petryk, J. ... Diallo, J.-S. (2022).
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Molecular Therapy,
30(9), 2998-3016.
https://doi.org/10.1016/j.ymthe.2022.04.025
Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G.
, Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A.
, Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Agerbo, E. ... Børglum, A. D. (2022).
Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.
Nature Genetics,
54(10), 1470-1478.
https://doi.org/10.1038/s41588-022-01171-3
Griffante, G., Hewelt-Belka, W., Albano, C., Gugliesi, F., Pasquero, S., Castillo Pacheco, S. F., Bajetto, G., Porporato, P. E., Mina, E., Vallino, M.
, Krapp, C., Jakobsen, M. R., Purdy, J., von Einem, J., Landolfo, S., Dell'Oste, V. & Biolatti, M. (2022).
IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection.
mBio,
13(3), e0043522.
https://doi.org/10.1128/mbio.00435-22
Hussmann, D., Starnawska, A., Kristensen, L.
, Daugaard, I., Thomsen, A.
, Kjeldsen, T., Hansen, C. S., Bybjerg-Grauholm, J.
, Dalsgaard Johansen, K., Ludvigsen, M., Kristensen, T., Larsen, T. S., Møller, M. B., Nyvold, C. G.
, Hansen, L. L. & Wojdacz, T. K. (2022).
IGHV-associated methylation signatures more accurately predict clinical outcomes of chronic lymphocytic leukemia patients than IGHV mutation load.
Haematologica,
107(4), 877-886.
https://doi.org/10.3324/haematol.2021.278477
Mikkelsen, R. R., Hundahl, M. P.
, Torp, C. K., Rodríguez-Carrio, J.
, Kjolby, M., Bruun, J. M. & Kragstrup, T. W. (2022).
Immunomodulatory and immunosuppressive therapies in cardiovascular disease and type 2 diabetes mellitus: A bedside-to-bench approach.
European Journal of Pharmacology,
925, Artikel 174998.
https://doi.org/10.1016/j.ejphar.2022.174998
Klæstrup, I. H., Pedersen, M. K. J., Holm, K. L.
, Alstrup, A. K. O., Romero-Ramos, M., Borghammer, P. & Van Den Berge, N. (2022).
Impact of aging on animal models of Parkinson´s disease.
Frontiers in Aging Neuroscience,
14, Artikel 909273.
https://doi.org/10.3389/fnagi.2022.909273
Schepelmann, M., Ranieri, M., Lopez-Fernandez, I., Webberley, T. S., Brennan, S. C., Yarova, P. L., Graca, J., Hanif, U.-K., Müller, C., Manhardt, T., Salzmann, M., Quasnichka, H., Price, S. A., Ward, D. T., Gilbert, T.
, Matchkov, V. V., Fenton, R. A., Herberger, A., Hwong, J. ... Riccardi, D. (2022).
Impaired Mineral Ion Metabolism in a Mouse Model of Targeted Calcium-Sensing Receptor (CaSR) Deletion from Vascular Smooth Muscle Cells.
Journal of the American Society of Nephrology : JASN,
33(7), 1323-1340.
https://doi.org/10.1681/ASN.2021040585
Jönsson, Å. L. M., Hernando, N., Knöpfel, T.
, Mogensen, S., Bendstrup, E., Hilberg, O., Christensen, J. H., Simonsen, U. & Wagner, C. A. (2022).
Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis.
Human Genomics,
16(1), Artikel 13.
https://doi.org/10.1186/s40246-022-00387-y
Gohr, M., Jakobsen, I. M., Helmig, R. B., Stengaard-Pedersen, K., Laurberg, T. B. & Troldborg, A. (2022).
Improved pregnancy outcomes in systemic lupus erythematosus: A retrospective study of pregnancies from a single centre in Denmark from 2010–2020 compared with the period 1990–2010.
Lupus,
31(10), 1202-1210.
https://doi.org/10.1177/09612033221107538
Moellgaard, M. H., Lund, I. C. B., Becher, N., Skytte, A.-B., Andreasen, L., Srebniak, M. I.
& Vogel, I. (2022).
Incidental finding of maternal malignancy in an unusual non-invasive prenatal test and a review of similar cases.
Clinical Case Reports,
10(10), Artikel e6280.
https://doi.org/10.1002/ccr3.6280
Jepsen, M. R., Østergaard, J. A., Conover, C. A.
, Wogensen, L., Birn, H., Krag, S. P., Fenton, R. A. & Oxvig, C. (2022).
Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy.
Metabolism: Clinical and Experimental,
132, Artikel 155218.
https://doi.org/10.1016/j.metabol.2022.155218
Fonager, S. V., Winther, G., Wittenborn, T. R., Jensen, L., Fahlquist-Hagert, C., Hansen, L. A., Füchtbauer, E.-M., Romero-Ramos, M. & Degn, S. E. (2022).
Increased maternofoetal transfer of antibodies in a murine model of systemic lupus erythematosus, but no immune activation and neuroimmune sequelae in offspring.
Journal of Neuroimmunology,
370, Artikel 577927.
https://doi.org/10.1016/j.jneuroim.2022.577927
Pedersen, J. G., Sokac, M., Sørensen, B. S., Luczak, A. A.
, Aggerholm-Pedersen, N., Birkbak, N. J., Øllegaard, T. H. & Jakobsen, M. R. (2022).
Increased Soluble PD-1 Predicts Response to Nivolumab plus Ipilimumab in Melanoma.
Cancers,
14(14), Artikel 3342.
https://doi.org/10.3390/cancers14143342
Kilian, M., Husby, S.
, Andersen, J., Moldoveanu, Z.
, Skov Sørensen, U. B., Reinholdt, J. & Tettelin, H. (2022).
Induction of Susceptibility to Disseminated Infection with IgA1 Protease-Producing Encapsulated Pathogens Streptococcus pneumoniae, Haemophilus influenzae Type b, and Neisseria meningitidis.
mBio,
13(3).
https://doi.org/10.1128/mbio.00550-22
Winzig, F., Gandhi, S., Lee, A., Würstle, S., Stanley, G. L., Capuano, I., Neuringer, I., Koff, J. L., Turner, P. E. & Chan, B. K. (2022).
Inhaled Bacteriophage Therapy for Multi-Drug Resistant Achromobacter.
Yale Journal of Biology and Medicine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765334/
Zevini, A., Palermo, E., Di Carlo, D., Alexandridi, M., Rinaldo, S., Paone, A., Cutruzzola, F., Etna, M. P., Coccia, E. M.
, Olagnier, D. & Hiscott, J. (2022).
Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I-Mediated Antiviral Responses in Primary Human Dendritic Cells.
Frontiers in cellular and infection microbiology,
12, Artikel 910864.
https://doi.org/10.3389/fcimb.2022.910864
Wu, A., Wolley, M. J., Matthews, A., Cowley, D., Welling, P. A.
, Fenton, R. A. & Stowasser, M. (2022).
In Primary Aldosteronism Acute Potassium Chloride Supplementation Suppresses Abundance and Phosphorylation of the Sodium-Chloride Cotransporter.
Kidney360,
3(11), 1909-1923.
https://doi.org/10.34067/KID.0003632022
Schulz, H., Dietrichs, D.
, Wehland, M., Corydon, T. J., Hemmersbach, R., Liemersdorf, C., Melnik, D., Hübner, N., Saar, K., Infanger, M.
& Grimm, D. (2022).
In Prostate Cancer Cells Cytokines Are Early Responders to Gravitational Changes Occurring in Parabolic Flights.
International Journal of Molecular Sciences ,
23(14), Artikel 7876.
https://doi.org/10.3390/ijms23147876
Hazrati, H., Kudsk, P., Ding, L., Uthe, H.
& Fomsgaard, I. S. (2022).
Integrated LC-MS and GC-MS-Based Metabolomics Reveal the Effects of Plant Competition on the Rye Metabolome.
Journal of Agricultural and Food Chemistry,
70(9), 3056–3066.
https://doi.org/10.1021/acs.jafc.1c06306
Wang, S., Ding, P., Yuan, J., Wang, H., Zhang, X., Chen, D., Ma, D., Zhang, X.
& Wang, F. (2022).
Integrative cross-species analysis of GABAergic neuron cell types and their functions in Alzheimer’s disease.
Scientific Reports,
12(1), Artikel 19358.
https://doi.org/10.1038/s41598-022-21496-7
Ahle, C. M.
, Stødkilde, K., Poehlein, A., Bömeke, M., Streit, W. R., Wenck, H., Reuter, J. H., Hüpeden, J.
& Brüggemann, H. (2022).
Interference and co-existence of staphylococci and Cutibacterium acnes within the healthy human skin microbiome.
Communications Biology,
5(1), Artikel 923.
https://doi.org/10.1038/s42003-022-03897-6