Biomedicine Seminar

Abstract:
Glioblastoma remains the most aggressive and lethal primary brain tumor, with limited advances in long-term survival despite decades of research. Recent breakthroughs in cancer neuroscience have improved our understanding of glioblastoma biology by revealing how tumor cells actively interact with and hijack neural circuits. Pioneering work has shown that glioma cells form functional synaptic connections with neurons, leveraging neural activity to drive tumor growth, invasion, and treatment resistance. These discoveries have positioned the neural microenvironment as a key malignancy driver and a promising therapeutic target. This talk will present the basic concepts of glioblastoma cancer neuroscience, highlight recent advances in therapeutic strategies, and discuss how integrating neuroscience into cancer research can open new avenues for glioblastoma interventions.