Institut for Biomedicin - Medarbejderportal

Peer-reviewed publikationer

Peer-reviewed publications

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Fagö-Olsen, H., Dines, L. M., Hjort-Sørensen, C. & Jensen, A. (2019). The Adenoids but Not the Palatine Tonsils Serve as a Reservoir for Bacteria Associated with Secretory Otitis Media in Small Children. mSystems, 4(1), 1-17. Artikel e00169-18. https://doi.org/10.1128/mSystems.00169-18

Gebhardt, A., Bergant, V., Schnepf, D., Moser, M., Meiler, A., Togbe, D., Mackowiak, C., Reinert, L., Paludan, S. R., Ryffel, B., Stukalov, A., Staeheli, P. & Pichlmair, A. (2019). The alternative cap-binding complex is required for antiviral defense in vivo. PLoS Pathogens, 15(12), Artikel e1008155. https://doi.org/10.1371/journal.ppat.1008155

Jayaprakash, S., Drakulic, S., Zhao, Z., Sander, B. & Golas, M. M. (2019). The ATPase BRG1/SMARCA4 is a protein interaction platform that recruits BAF subunits and the transcriptional repressor REST/NRSF in neural progenitor cells. Molecular and Cellular Biochemistry, 461(1-2), 171-182. https://doi.org/10.1007/s11010-019-03600-0

Berg, P., Svendsen, S. L. S. C., Sørensen, M. V., Jensen-Fangel, S., Jeppesen, M., Kunzelmann, K. & Leipziger, J. G. (2019). The Cystic Fibrosis Urine Test. Abstract fra American Society of Nephrology - Kidney Week 2019, Washington DC, Washington, USA. https://www.asn-online.org/education/kidneyweek/2019/program-abstract.aspx?controlId=3234422

Murali, S. K., Aroankins, T. S., Moeller, H. B. & Fenton, R. A. (2019). The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance. Cells, 8(3). https://doi.org/10.3390/cells8030265

Phikulsod, P., Owattanapanich, W., Bill, M., Rotchanapanya, W., Hansen, M. C., Hokland, M. & Hokland, P. (2019). The Development of Personalized Medicine: Acute Myeloid Leukemia as a Model. Siriraj Medical Journal, 71(5), 414-425. https://doi.org/10.33192/Smj.2019.62

Engbjerg, J. S., Sardella, D., Bordoni, L., Trepiccione, F., Capasso, G., Østergaard, L., Rhodes, G. G., Sandoval, R., Ring, T., Molitoris, B. & Frische, S. (2019). The Distribution of Blood in Renal Glomerular Capillaries Is a New Physiological Parameter, Which Is Affected by Diabetes and ACE-inhibition. The FASEB Journal, 33(S1). https://doi.org/10.1096/fasebj.2019.33.1_supplement.748.11

Sørensen, U. B. S., Klaas, I. C., Boes, J. & Farre, M. (2019). The distribution of clones of Streptococcus agalactiae (group B streptococci) among herdspersons and dairy cows demonstrates lack of host specificity for some lineages. Veterinary Microbiology, 235, 71-79. https://doi.org/10.1016/j.vetmic.2019.06.008

Hu, L., Zachariae, E. D., Larsen, U. G., Vilhardt, F. & Petersen, S. V. (2019). The dynamic uptake and release of SOD3 from intracellular stores in macrophages modulates the inflammatory response. Redox Biology, 26, Artikel 101268. https://doi.org/10.1016/j.redox.2019.101268

Iena, F. M., Vegger, J. B., Thomsen, J. S., Brüel, A. & Lebeck, J. (2019). The Effect of High-Fat Diet on Adipose Tissue Glycerol Metabolism Is Influenced by Sex and GLP-1 Agonist Treatment. Poster-session præsenteret på American Diabetes Association 79th Scientific Sessions, San Francisco, California, USA.

Leduc-Galindo, D., Qvist, P., Tóth, A. E., Fryland, T., Nielsen, M. S., Børglum, A. D. & Christensen, J. H. (2019). The effect of hypoxia on ZEB1 expression in a mimetic system of the blood-brain barrier. Microvascular Research, 122, 131-135. https://doi.org/10.1016/j.mvr.2018.08.004

Hammer, R. E., Richner, M., Vægter, C. B., Karlsson, P. & Nyengaard, J. R. (2019). The effect of Recombinant Botulinum Neurotoxin A on neuropathic pain in Spared Nerve Injury mouse model. Poster-session præsenteret på 11th Congress of the European Pain Federation EFIC, Valencia, Spanien.

Toth, A. E., Nielsen, S. S. E., Tomaka, W., Abbott, N. J. & Nielsen, M. S. (2019). The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells. Fluids and Barriers of the CNS, 16(1), Artikel 14. https://doi.org/10.1186/s12987-019-0134-9

Christensen, T. & Muchardt, C. (2019). The epigenetics of multiple sclerosis. I O. Binda (red.), Chromatin Signaling and Neurological Disorders (s. 97-118). Academic Press.

Hollyer, T. R., Bordoni, L., Kousholt, B. S., van Luijk, J., Ritskes-Hoitinga, M. & Østergaard, L. (2019). The evidence for the physiological effects of lactate on the cerebral microcirculation: a systematic review. Journal of Neurochemistry, 148(6), 712-730. https://doi.org/10.1111/jnc.14633

Clarkson, A. N., Boothman-Burrell, L., Dósa, Z., Nagaraja, R. Y., Jin, L., Parker, K., van Nieuwenhuijzen, P. S., Neumann, S., Gowing, E. K., Gavande, N., Ahring, P. K., Holm, M. M., Hanrahan, J. R., Nicolazzo, J. A., Jensen, K. & Chebib, M. (2019). The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia. Journal of Cerebral Blood Flow and Metabolism, 39(7), 1266-1282. https://doi.org/10.1177/0271678X18755628

Jensen, I. S., Yuan, J., He, J., Lin, L., Sander, B. & Golas, M. M. (2019). The FlpTRAP system for purification of specific, endogenous chromatin regions. Analytical Biochemistry, 587, Artikel 113418. https://doi.org/10.1016/j.ab.2019.113418

Stempel, M., Chan, B., Juranić Lisnić, V., Krmpotić, A., Hartung, J., Paludan, S. R., Füllbrunn, N., Lemmermann, N. A. W. & Brinkmann, M. M. (2019). The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. EMBO Journal, 38(5), Artikel e100983. https://doi.org/10.15252/embj.2018100983

Klastrup, L. K., Bak, S. T. & Nielsen, A. L. (2019). The influence of paternal diet on sncRNA-mediated epigenetic inheritance. Molecular Genetics and Genomics, 294(1), 1-11. https://doi.org/10.1007/s00438-018-1492-8

Nyegaard, M. & Overgaard, M. T. (2019). The International Calmodulinopathy Registry: recording the diverse phenotypic spectrum of un-CALM hearts. European Heart Journal, 40(35), 2976-2978. https://doi.org/10.1093/eurheartj/ehz463

Nielsen, M. C., Andersen, M. N., Rittig, N., Rødgaard-Hansen, S., Grønbaek, H., Moestrup, S. K., Møller, H. J. & Etzerodt, A. (2019). The macrophage-related biomarkers sCD163 and sCD206 are released by different shedding mechanisms. Journal of Leukocyte Biology, 106(5), 1129-1138. https://doi.org/10.1002/JLB.3A1218-500R

Falkenberg, K. D., Rohlenova, K., Luo, Y. & Carmeliet, P. (2019). The metabolic engine of endothelial cells. Nature Metabolism, 1(10), 937-946. https://doi.org/10.1038/s42255-019-0117-9

Amoushahi, M., Sunde, L. & Lykke-Hartmann, K. (2019). The pivotal roles of the NOD-like receptors with a PYD domain, NLRPs, in oocytes and early embryo development. Biology of Reproduction, 101(2), 284-296. https://doi.org/10.1093/biolre/ioz098

Chapeton-Montes, D., Plourde, L., Bouchier, C., Ma, L., Diancourt, L., Criscuolo, A., Popoff, M. R. & Brüggemann, H. (2019). The population structure of Clostridium tetani deduced from its pan-genome. Scientific Reports, 9(1), Artikel 11220. https://doi.org/10.1038/s41598-019-47551-4

Bak, R. O. (2019). The Potential of CRISPR/Cas9 in Hematotherapy. Stem Cells and Development, 28(11), 710-711. https://doi.org/10.1089/scd.2019.0079

Olesen, M. S., Hauge, B., Ohrt, L., Olesen, T. N., Roskær, J., Bæk, V., Elbæk, H. O., Nøhr, B., Nyegaard, M., Overgaard, M. T., Humaidan, P., Forman, A. & Agerholm, I. (2019). Therapeutic endometrial scratching and implantation after in vitro fertilization: a multicenter randomized controlled trial. Fertility and Sterility, 112(6), 1015-1021. https://doi.org/10.1016/j.fertnstert.2019.08.010

Axelgaard, E., Jensen, T. I. & Bak, R. O. (2019). Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British Journal of Haematology, 185(5), 821-835. https://doi.org/10.1111/bjh.15851

Gonçalves, O. S. L., Christiansen, G., Holm, A., Herrmann, B., Klintstedt, M., Petersen, S. B. & Birkelund, S. (2019). The repeated 36 amino acid motif of Chlamydia trachomatis Hc2 protein binds to the major groove of DNA. Research in Microbiology, 170(6-7), 256-262. https://doi.org/10.1016/j.resmic.2019.08.002

Bjerre, H. L., Christensen, J. B., Buus, N. H., Simonsen, U. & Su, J. (2019). The role of aliskiren in the management of hypertension and major cardiovascular outcomes: a systematic review and meta-analysis. Journal of Human Hypertension, 33(11), 795-806. https://doi.org/10.1038/s41371-018-0149-8

Cedzynski, M., Thielens, N. M., Mollnes, T. E. & Vorup-Jensen, T. (red.) (2019). The role of complement in health and disease. Frontiers Media S.A. Frontiers in Immunology https://doi.org/10.3389/978-2-88963-159-9

Poulsen, E. T., Nielsen, N. S., Scavenius, C., Mogensen, E. H., Risør, M. W., Runager, K., Lukassen, M. V., Rasmussen, C. B., Christiansen, G., Richner, M., Vorum, H. & Enghild, J. J. (2019). The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation. Journal of Biological Chemistry, 294(31), 11817-11828. https://doi.org/10.1074/jbc.RA119.009050

Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi-Hemami, H., Teilum, K. & Ellgaard, L. (2019). The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework. Journal of Biological Chemistry, 294(22), 8745-8759. https://doi.org/10.1074/jbc.RA119.007491

Li, K., Neumann, K., Duhan, V., Namineni, S., Hansen, A. L., Wartewig, T., Kurgyis, Z., Holm, C. K., Heikenwalder, M., Lang, K. S. & Ruland, J. (2019). The uric acid crystal receptor Clec12A potentiates type I interferon responses. Proceedings of the National Academy of Sciences (PNAS), 116(37), 18544-18549. https://doi.org/10.1073/pnas.1821351116

Jensen, P. S., Aalkjaer, C. & Bek, T. (2019). The vasodilating effect of glucose differs among vessels at different branching level in the porcine retina ex vivo. Experimental Eye Research, 179, 150-156. https://doi.org/10.1016/j.exer.2018.11.006

Matrone, C., Iannuzzi, F. & Annunziato, L. (2019). The Y ₆₈₂ ENPTY ₆₈₇ motif of APP: Progress and insights toward a targeted therapy for Alzheimer's disease patients. Ageing Research Reviews, 52, 120-128. https://doi.org/10.1016/j.arr.2019.04.003

Maxel, T., Smidt, K., Petersen, C. C., Honoré, B., Christensen, A. K., Jeppesen, P. B., Brock, B., Rungby, J., Palmfeldt, J. & Larsen, A. (2019). The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells. Scientific Reports, 9(1), Artikel 8589. https://doi.org/10.1038/s41598-019-44954-1

Hanifa, M. A., Skott, M., Maltesen, R. G., Rasmussen, B. S., Nielsen, S., Frøkiær, J., Ring, T. & Wimmer, R. (2019). Tissue, urine and blood metabolite signatures of chronic kidney disease in the 5/6 nephrectomy rat model. Metabolomics, 15(8), Artikel 112. https://doi.org/10.1007/s11306-019-1569-3

Pedersen, L. H. (2019). To treat or not to treat: Do not let fear decide whether to use medication during pregnancy. Acta Obstetricia et Gynecologica Scandinavica, 98(7), 821-822. https://doi.org/10.1111/aogs.13643

Ørstrup, L. H., Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, J. & Glud, A. N. (2019). Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method. Heliyon, 5(11), Artikel e02892. https://doi.org/10.1016/j.heliyon.2019.e02892, https://doi.org/10.1016/j.heliyon.2019.e02892

Musliner, K., Vilhjálmsson, B. J., Albiñana Climent, C., Krebs, M. D., Zandi, P. P., Agerbo, E., Mortensen, P. B., Werge, T., Børglum, A. & Østergaard, S. D. (2019). Towards precision medicine in psychiatric care: Using polygenic risk scores to predict outcomes in hospital-treated depression patients . S88-S88. Abstract fra World Congress of Psychiatric Genetics , Anaheim , California, USA.

Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, K. J., Pers, T. H., Khodosevich, K., Simons, B. D. & Jensen, K. B. (2019). Tracing the origin of adult intestinal stem cells. Nature, 570(7759), 107-111. https://doi.org/10.1038/s41586-019-1212-5

Lin, L. & Luo, Y. (2019). Tracking CRISPR's Footprints. I Y. Luo (red.), Methods in Molecular Biology: Methods and Protocols (s. 13-28). Springer Science+Business Media. https://doi.org/10.1007/978-1-4939-9170-9_2

Habekost, M., Jørgensen, A. L., Qvist, P. & Denham, M. (2019). Transcriptomic profiling of porcine pluripotency identifies species-specific reprogramming requirements for culturing iPSCs. Stem Cell Research, 41, Artikel 101645. https://doi.org/10.1016/j.scr.2019.101645

Delaidelli, A., Jan, A., Herms, J. & Sorensen, P. H. (2019). Translational control in brain pathologies: biological significance and therapeutic opportunities. Acta Neuropathologica, 137(4), 535-555. https://doi.org/10.1007/s00401-019-01971-8

Rasmussen, C. K., Hansen, E. S., Ernst, E. & Dueholm, M. (2019). Two- and three-dimensional transvaginal ultrasonography for diagnosis of adenomyosis of the inner myometrium. Reproductive BioMedicine Online, 38(5), 750-760. https://doi.org/10.1016/j.rbmo.2018.12.033

van Diggelen, F., Hrle, D., Apetri, M., Christiansen, G., Rammes, G., Tepper, A. & Otzen, D. E. (2019). Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation. PLoS One, 14(3), Artikel 0213663. https://doi.org/10.1371/journal.pone.0213663

Budolfsen, C., Faber, J., Grimm, D., Krüger, M., Bauer, J., Wehland, M., Infanger, M. & Magnusson, N. E. (2019). Tyrosine Kinase Inhibitor-Induced Hypertension: Role of Hypertension as a Biomarker in Cancer Treatment. Current Vascular Pharmacology, 17(6), 618-634. https://doi.org/10.2174/1570161117666190130165810

Rodríguez-Rodríguez, R., Ackermann, T. N., Plaza, J. A., Simonsen, U., Matchkov, V., Llobera, A. & Munoz-Berbel, X. (2019). Ultrasensitive photonic microsystem enabling sub-micrometric monitoring of arterial oscillations for advanced cardiovascular studies. Frontiers in Physiology, 10, Artikel 940. https://doi.org/10.3389/fphys.2019.00940

Vestergaard, E. T., Jessen, N., Møller, N. & Jørgensen, J. O. L. (2019). Unacylated Ghrelin does not Acutely Affect Substrate Metabolism or Insulin Sensitivity in Men with Type 2 Diabetes. Journal of Clinical Endocrinology and Metabolism, 104(6), 2435-2442. https://doi.org/10.1210/jc.2018-02601

Ferreira, N., Saraiva, M. J. & Almeida, M. R. (2019). Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis. International Journal of Molecular Sciences , 20(6), Artikel 1287. https://doi.org/10.3390/ijms20061287

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Revideret 21.08.2025