Skovdal, S. M., Christiansen, S. H., Johansen, K. S., Viborg, O., Bruun, N. H., Jensen-Fangel, S., Holm, I. E., Vorup-Jensen, T. & Petersen, E. (2019).
Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs.
PLoS One,
14(10), Artikel e0223647.
https://doi.org/10.1371/journal.pone.0223647
Zhou, Y., Jones, N. C., Pedersen, J. N., Perez, B.
, Hoffmann, S. V., Petersen, S. V., Pedersen, J. S., Perriman, A., Kristensen, P., Gao, R.
& Guo, Z. (2019).
Insight into the structure and activity of surface-engineered lipase biofluids.
ChemBioChem,
20(10), 1266-1272.
https://doi.org/10.1002/cbic.201800819
Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019).
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
Nature Communications,
10, Artikel 2548.
https://doi.org/10.1038/s41467-019-10461-0Zhang, W., Voloudakis, G.
, Rajagopal, V. M., Readhead, B., Dudley, J. T., Schadt, E. E., Björkegren, J. L. M., Kim, Y., Fullard, J. F., Hoffman, G. E. & Roussos, P. (2019).
Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.
Nature Communications,
10(1), 1-13. Artikel 3834.
https://doi.org/10.1038/s41467-019-11874-7Kaleviste, E., Saare, M., Leahy, T. R., Bondet, V., Duffy, D.
, Mogensen, T. H., Jørgensen, S. E., Nurm, H., Ip, W., Davies, E. G., Sauer, S., Syvänen, A. C., Milani, L., Peterson, P. & Kisand, K. (2019).
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
European Journal of Immunology,
49(5), 790-800.
https://doi.org/10.1002/eji.201847955Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M. ... Koenen, K. C. (2019).
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Nature Communications,
10(1), Artikel 4558.
https://doi.org/10.1038/s41467-019-12576-wNandakumar, R., Tschismarov, R., Meissner, F.
, Prabakaran, T., Krissanaprasit, A., Farahani, E., Zhang, B. C., Assil, S., Martin, A., Bertrams, W.
, Holm, C. K., Ablasser, A.
, Klause, T., Thomsen, M. K., Schmeck, B.
, Howard, K. A., Henry, T.
, Gothelf, K. V., Decker, T.
& Paludan, S. R. (2019).
Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling.
Nature Microbiology,
4, 701-713.
https://doi.org/10.1038/s41564-019-0367-z
Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019).
Investigating the association between body fat and depression via Mendelian randomization.
Translational Psychiatry,
9(1), Artikel 184.
https://doi.org/10.1038/s41398-019-0516-4
Alstrup, T., Eijken, M., Bohn, A. B., Møller, B. & Damsgaard, T. E. (2019).
Isolation of Adipose Tissue-Derived Stem Cells: Enzymatic Digestion in Combination with Mechanical Distortion to Increase Adipose Tissue-Derived Stem Cell Yield from Human Aspirated Fat.
Current Protocols in Stem Cell Biology,
48(1), Artikel e68.
https://doi.org/10.1002/cpsc.68
King, D., Glynn, M. D., Cindric, S., Kernan, D., O’Connell, T., Hakimjavadi, R., Kearney, S., Ackermann, T., Berbel, X. M., Llobera, A.
, Simonsen, U., Laursen, B. E., Redmond, E. M., Cahill, P. A. & Ducrée, J. (2019).
Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform.
Scientific Reports,
9, Artikel 4157.
https://doi.org/10.1038/s41598-019-40612-8Therkildsen, J. R., Christensen, M. G., Tingskov, S. J., Wehmöller, J., Nørregaard, R. & Praetorius, H. A. (2019).
Lack of P2X
7
Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin–Producing Escherichia coli.
American Journal of Pathology,
189(6), 1201-1211.
https://doi.org/10.1016/j.ajpath.2019.02.013
Larsen, J. B., Andersen, A. S.
, Hvas, C. L., Thiel, S., Lassen, M. R.
, Hvas, A.-M. & Hansen, A. T. (2019).
Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia.
American Journal of Reproductive Immunology Online,
81(4), e13092. Artikel e13092.
https://doi.org/10.1111/aji.13092
Xiang, X., Luo, L., Nodzyński, M., Li, C., Han, P., Dou, H.
, Petersen, T. S., Liang, X., Pan, X., Qu, K., Yang, L.
, Dang, Y., Liu, X.
, Bolund, L., Zhang, X., Tong, G., Xing, Y.
, Luo, Y. & Lin, L. (2019).
LION: a simple and rapid method to achieve CRISPR gene editing.
Cellular and Molecular Life Sciences,
76(13), 2633-2645.
https://doi.org/10.1007/s00018-019-03064-x
Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019).
Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model.
Molecular Therapy,
27(8), 1424-1435.
https://doi.org/10.1016/j.ymthe.2019.05.002
Andersen, M. A., Sotty, F.
, Jensen, P. H., Badolo, L., Jeggo, R., Smith, G. P. & Christensen, K. V. (2019).
Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications.
eNeuro ,
6(6), Artikel ENEURO.0453-18.2019.
https://doi.org/10.1523/ENEURO.0453-18.2019
Pedersen, J. N., Jiang, Z.
, Christiansen, G., Lee, J. C.
, Pedersen, J. S. & Otzen, D. E. (2019).
Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures.
Biochimica et Biophysica Acta - Proteins and Proteomics,
1867(5), 519-528.
https://doi.org/10.1016/j.bbapap.2018.11.007
Freese, N. H., Estrada, A. R., Blakley, I. C.
, Duan, J. & Loraine, A. E. (2019).
Many rice genes are differentially spliced between roots and shoots but cytokinin has minimal effect on splicing.
Plant Direct,
3(5), Artikel e00136.
https://doi.org/10.1002/pld3.136Scavenius, C., Poulsen, E. C., Thøgersen, I. B., Roebuck, M., Frostick, S., Bou-Gharios, G., Yamamoto, K.
, Deleuran, B. & Enghild, J. J. (2019).
Matrix-degrading protease ADAMTS-5 cleaves inter-αinhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients.
Journal of Biological Chemistry,
294(42), 15495-15504.
https://doi.org/10.1074/jbc.RA119.008844
Mohammad-Beigi, H., Hosseini, A., Adeli, M., Ejtehadi, M. R.
, Christiansen, G., Sahin, C., Tu, Z., Tavakol, M., Dilmaghani-Marand, A., Nabipour, I., Farzadfar, F.
, Otzen, D. E., Mahmoudi, M. & Hajipour, M. J. (2019).
Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein.
ACS Nano,
13(3), 3243-3256.
https://doi.org/10.1021/acsnano.8b08983
Goossens, P., Rodriguez-Vita, J.
, Etzerodt, A., Masse, M., Rastoin, O., Gouirand, V., Ulas, T., Papantonopoulou, O., Van Eck, M., Auphan-Anezin, N., Bebien, M., Verthuy, C., Vu Manh, T. P., Turner, M., Dalod, M., Schultze, J. L. & Lawrence, T. (2019).
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
Cell Metabolism,
29(6), 1376-1389.e4.
https://doi.org/10.1016/j.cmet.2019.02.016Gormsen, L. C., Søndergaard, E., Christensen, N. L., Brøsen, K.
, Jessen, N. & Nielsen, S. (2019).
Metformin increases endogenous glucose production in non-diabeticindividuals and individuals with recent-onset type 2 diabetes.
Diabetologia,
62, 1251–1256.
https://doi.org/10.1007/s00125-019-4872-7
Myhre, C. L., Thygesen, C., Villadsen, B., Vollerup, J., Ilkjaer, L., Krohn, K. T., Grebing, M., Zhao, S., Khan, A. M., Dissing-Olesen, L.
, Jensen, M. S., Babcock, A. A. & Finsen, B. (2019).
Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.
Frontiers in Cellular Neuroscience,
13, Artikel 308.
https://doi.org/10.3389/fncel.2019.00308Due, H.
, Schönherz, A. A., Ryø, L., Primo, M. N., Jespersen, D. S.
, Thomsen, E. A., Roug, A. S., Xiao, M., Tan, X., Pang, Y., Young, K. H.
, Bøgsted, M., Mikkelsen, J. G. & Dybkær, K. (2019).
MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma.
Blood Advances,
3(7), 1185-1196.
https://doi.org/10.1182/bloodadvances.2018029660Bouzinova, E., Lykke-Hartmann, K., Nyengaard, J. R., Beck, H. C.
, Matchkov, V. & Staehr, C. (2019).
Migraine-associated mutation in the a2 isoform Na,K-ATPase is associated with cardiomyopathy-like changes in the mouse heart.
Acta Physiologica (Print),
227(S721).
Kogelman, L. J. A., Esserlind, A.-L., Francke Christensen, A., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B.
, Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Folkmann Hansen, T. & DBDS Genomic Consortium, The International Headache Genetics Consortium (2019).
Migraine polygenic risk score associates with efficacy of migraine-specific drugs.
Neurology: Genetics,
5(6), Artikel e364.
https://doi.org/10.1212/NXG.0000000000000364Riis, S., Christensen, B., Sørensen, B., Møller, A. B., Husted, A. S.
, Pedersen, S. B., Schwartz, T. W.
, Jørgensen, J. O. L. & Jessen, N. (2019).
Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males.
Journal of applied physiology (Bethesda, Md. : 1985),
126(3), 569-577.
https://doi.org/10.1152/japplphysiol.00989.2018
Møller, A. B., Lønbro, S., Farup, J., Voss, T. S., Rittig, N., Wang, J., Højris, I., Mikkelsen, U. R. & Jessen, N. (2019).
Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy.
Journal of Cancer Research and Clinical Oncology,
145(6), 1449-1460.
https://doi.org/10.1007/s00432-019-02911-5
Buken, C., Sahana, J., Corydon, T. J., Melnik, D., Bauer, J.
, Wehland, M., Krüger, M., Balk, S., Abuagela, N., Infanger, M.
& Grimm, D. (2019).
Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity.
Scientific Reports,
9(1), Artikel 11882.
https://doi.org/10.1038/s41598-019-48378-9
Mohanakumar, S., Telinius, N., Kelly, B., Lauridsen, H., Bødtkjer, D. M. B., Pedersen, M., de Leval, M.
& Hjortdal, V. E. (2019).
Morphology and Function of the Lymphatic Vasculature in Patients With a Fontan Circulation.
Circulation: Cardiovascular Imaging,
12(4), e008074. Artikel e008074.
https://doi.org/10.1161/CIRCIMAGING.118.008074
Zhang, P., Gu, L., Cong, J., Zhang, J.
, Thomsen, J. S., Andreasen, A., Chang, S.-J., Deng, S.-Q., Xing, J. & Zhai, X.-Y. (2019).
Morphology of the initial nephron-collecting duct connection in mice using computerized 3D tracing and electron microscopy.
Biochemical and Biophysical Research Communications,
509(1), 114-118.
https://doi.org/10.1016/j.bbrc.2018.12.079DellaValle, B., Hasseldam, H., Johansen, F. F., Iversen, H. K.
, Rungby, J. & Hempel, C. (2019).
Multiple Soluble Components of the Glycocalyx Are Increased in Patient Plasma After Ischemic Stroke.
Stroke,
50(10), 2948-2951.
https://doi.org/10.1161/STROKEAHA.119.025953Blondelle, J., Marrocco, V.
, Clark, M., Desmond, P., Myers, S., Nguyen, J., Wright, M., Bremner, S., Pierantozzi, E., Ward, S., Estève, E., Sorrentino, V., Ghassemian, M.
& Lange, S. (2019).
Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.
Communications Biology,
2(1), Artikel 178.
https://doi.org/10.1038/s42003-019-0405-7Witt, A. H., Søgaard Kristensen, R., Fuglsang-Frederiksen, A., Pedersen, T. H., Finnerup, N. B., Kasch, H. & Tankisi, H. (2019).
Muscle velocity recovery cycles in neurogenic muscles.
Clinical Neurophysiology,
130(9), 1520-1527.
https://doi.org/10.1016/j.clinph.2019.05.030
Migliorini, L. B.
, Brüggemann, H., de Sales, R. O., Koga, P. C. M., de Souza, A. V., Martino, M. D. V., Galhardo, R. S. & Severino, P. (2019).
Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin: Genotypic and Phenotypic Differences Between the Pseudomonas aeruginosa Strain PA14 and Clinical Isolates.
Frontiers in Microbiology,
10, Artikel 1553.
https://doi.org/10.3389/fmicb.2019.01553Carter-Timofte, M. E., Hansen, A. F., Christiansen, M., Paludan, S. R. & Mogensen, T. H. (2019).
Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection.
Genes and Immunity,
20(3), 214-223.
https://doi.org/10.1038/s41435-018-0027-y
Olawi, N., Krüger, M.
, Grimm, D., Infanger, M.
& Wehland, M. (2019).
Nebivolol in the Treatment of Arterial Hypertension.
Basic & Clinical Pharmacology & Toxicology,
125(3), 189-201.
https://doi.org/10.1111/bcpt.13248
Bijkerk, R., Aleksinskaya, M. A., Duijs, J. M. G. J., Veth, J., Husen, B., Reiche, D., Prehn, C., Adamski, J., Rabelink, T. J.
, De Mey, J. G. R. & van Zonneveld, A. J. (2019).
Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation.
Clinical Science,
133(2), 239-252.
https://doi.org/10.1042/CS20180882Dembic, M., Andersen, H. S., Bastin, J., Doktor, T. K.
, Corydon, T. J., Sass, J. O., Costa, A. L., Djouadi, F. & Andresen, B. S. (2019).
Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease.
Molecular Genetics and Metabolism,
126(1), 64-76.
https://doi.org/10.1016/j.ymgme.2018.10.004Mey, L., Jung, M., Roos, F., Blaheta, R., Hegele, A., Kinscherf, R.
& Urbschat, A. (2019).
NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells.
Journal of Cancer Research and Clinical Oncology,
145(6), 1405-1416.
https://doi.org/10.1007/s00432-019-02901-7Frich, C. K., Krüger, F.
, Walther, R., Domar, C., Andersen, A. H. F., Tvilum, A., Dagnæs-Hansen, F., Denton, P. W., Tolstrup, M., Paludan, S. R., Münch, JJ.
& Zelikin, A. N. (2019).
Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs.
Journal of Controlled Release,
294, 298-310.
https://doi.org/10.1016/j.jconrel.2018.12.016