Peer-reviewed publications

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Rindom, E., Kristensen, A. M., Overgaard, K., Vissing, K. & de Paoli, F. V. (2019). Activation of mTORC1 signalling in rat skeletal muscle is independent of the EC-coupling sequence but dependent on tension per se in a dose-response relationship. Acta Physiologica, 227(3), Article e13336. https://doi.org/10.1111/apha.13336

Riis, S., Møller, A. B., Dollerup, O. L., Høffner, L., Jessen, N. & Madsen, K. (2019). Acute and sustained effects of a periodized carbohydrate intake using the sleep-low model in endurance-trained males. Scandinavian Journal of Medicine & Science in Sports, 29(12), 1866-1880. https://doi.org/10.1111/sms.13541

Graae, A.-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjolby, M., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A. ... Holst, B. (2019). ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations. Diabetes, 68(3), 502-514. https://doi.org/10.2337/db18-0418

Krabbe, S., Paradiso, E., d’Aquin, S., Bitterman, Y., Courtin, J., Xu, C., Yonehara, K., Markovic, M., Müller, C., Eichlisberger, T., Gründemann, J., Ferraguti, F. & Lüthi, A. (2019). Adaptive disinhibitory gating by VIP interneurons permits associative learning. Nature Neuroscience, 22, 1834-1843. https://doi.org/10.1038/s41593-019-0508-y

Fenton, R. A., Murali, S. K., Kaji, I., Akiba, Y., Kaunitz, J. D., Kristensen, T. B., Poulsen, S. B., Dominguez Rieg, J. A. & Rieg, T. (2019). Adenylyl cyclase 6 expression is essential for cholera toxin-induced diarrhea. The Journal of Infectious Diseases, 220(11), 1719-1728. https://doi.org/10.1093/infdis/jiz013

Comuth, W., de Maat, M. P. M., van de Kerkhof, D., Malczynski, J., Husted, S., Kristensen, S. D. & Münster, A.-M. B. (2019). Adherence to dabigatran etexilate in atrial fibrillation patients intended to undergo electrical cardioversion. European heart journal - Cardiovascular pharmacotherapy, 5(2), 91-99. https://doi.org/10.1093/ehjcvp/pvy047

Toxvig, A. K., Wehland, M., Grimm, D., Infanger, M. & Krüger, M. (2019). A Focus on Riociguat in the Treatment of Pulmonary Arterial Hypertension. Basic & Clinical Pharmacology & Toxicology, 125(3), 202-214. https://doi.org/10.1111/bcpt.13272

Lodberg, A., van der Eerden, B. C. J., Boers-Sijmons, B., Thomsen, J. S., Brüel, A., van Leeuwen, J. P. T. M. & Eijken, M. (2019). A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice. F A S E B Journal, 33(5), 6001-6010. https://doi.org/10.1096/fj.201801969RR

Gerring, Z. F., Gamazon, E. R., Derks, E. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression. PLoS Genetics, 15(7), e1008245. Article e1008245. https://doi.org/10.1371/journal.pgen.1008245

Christiansen, M. K., Winther, S., Nissen, L., Johansen, J. K., Westra, J., Holm, N. R., Frost, L., Bøtker, H. E., Christiansen, E. H., Böttcher, M. & Nyegaard, M. (2019). A genetic risk score improves discrimination of hemodynamically obstructive coronary artery disease (CAD) beyond the CAD Consortium scores in patients at low-to-intermediate risk of CAD. Abstract from European Society of Cardiology Congress 2019, Paris, France.

Christiansen, M. K., Nissen, L., Winther, S., Frost, L., Johansen, J. K., Jensen, H. K., Bøtker, H. E., Böttcher, M. & Nyegaard, M. (2019). A genetic risk score is associated with increased coronary plaque burden but not specific plaque features: a coronary computed tomography study. Abstract from European Society of Cardiology Congress 2019, Paris, France.

Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D. ... Werge, T. (2019). A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience, 22(3), 353-361. https://doi.org/10.1038/s41593-018-0320-0

Nielsen, A. W., Klose-Jensen, R., Hartlev, L. B., Boel, L. W. T., Thomsen, J. S., Keller, K. K. & Hauge, E. M. (2019). Age-related histological changes in calcified cartilage and subchondral bone in femoral heads from healthy humans. Bone, 129, Article 115037. https://doi.org/10.1016/j.bone.2019.115037

Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, T., Nordentoft, M., Thompson, W. K. & Benros, M. E. (2019). A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population. Translational Psychiatry, 9(1), Article 283. https://doi.org/10.1038/s41398-019-0622-3

Nissen, S. K., Shrivastava, K., Schulte, C., Otzen, D. E., Goldeck, D., Berg, D., Møller, H. J., Maetzler, W. & Romero-Ramos, M. (2019). Alterations in Blood Monocyte Functions in Parkinson's Disease. Movement Disorders, 34(11), 1711-1721. https://doi.org/10.1002/mds.27815

de Morree, A., Klein, J. D. D., Gan, Q., Farup, J., Urtasun, A., Kanugovi, A., Bilen, B., Van Velthoven, C. T. J., Quarta, M. & Rando, T. A. (2019). Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science, 366(6466), 734-738. https://doi.org/10.1126/science.aax1694

Ho, P. Y., Li, H., Cheng, L., Bhalla, V., Fenton, R. A. & Hallows, K. R. (2019). AMPK phosphorylation of the β₁Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells. American journal of physiology. Renal physiology, 317(6), F1513-F1525. https://doi.org/10.1152/ajprenal.00592.2018

Matchkov, V. V., Duy, N. T., Rajanathan, R., Jeppesen, P. B., Bouzinova, E. & Staehr, C. (2019). An abundance of the Na,K-ATPase modulates homeostasis of blood glucose.. 134-134. Abstract from The Annual Meeting of The Scandinavian Physiological Society 2019, Reykjavik, Iceland.

Schelde, K. K., Nicholls , K., Dagnæs-Hansen, F., Bunting , K., Rawsthorne, H., Andersen, B., Finnis, C., Williamson, M., Cameron, J. & Howard, K. (2019). A new class of recombinant human albumin with multiple surface thiols exhibit stable conjugation, and enhanced FcRn binding and blood circulation. Journal of Biological Chemistry, 294(10), 3735-3743. https://doi.org/10.1074/jbc.RA118.005870

Moeller, H. B. (2019). A new ‘tail’ of aquaporin-2. Journal of Physiology, 597(6), 1429-1430. https://doi.org/10.1113/JP277502

Vestergaard, N., Cehofski, L. J., Honoré, B., Aasbjerg, K. & Vorum, H. (2019). Animal Models Used to Simulate Retinal Artery Occlusion: A Comprehensive Review. Translational vision science & technology, 8(4), Article 23. https://doi.org/10.1167/tvst.8.4.23

Rud, C., Pedersen, A. K. N., Wilkens, T. L., Borre, M., Andersen, J. R., Moeller, H. B., Dahlerup, J. F. & Hvas, C. L. (2019). An iso-osmolar oral supplement increases natriuresis and does not increase stomal output in patients with an ileostomy: A randomised, double-blinded, active comparator, crossover intervention study. Clinical Nutrition, 38(5), 2079-2086. https://doi.org/10.1016/j.clnu.2018.10.014

Castiello, L., Zevini, A., Vulpis, E., Muscolini, M., Ferrari, M., Palermo, E., Peruzzi, G., Krapp, C., Jakobsen, M., Olagnier, D., Zingoni, A., Santoni, A. & Hiscott, J. (2019). An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation. Cancer Immunology, Immunotherapy, 68(9), 1479-1492. https://doi.org/10.1007/s00262-019-02380-2

Faergeman, S. L., Gregersen, P. A., Andersen, B. N., Becher, N. & Bojesen, A. B. (2019). A novel de novo frameshift variant identified in AHDC1 in two unrelated boys with Xia-Gibbs syndrome. Poster session presented at ESHG conference 2019, Gothenburg, Sweden.

Santos, L., Colman, L., Contreras, P., Chini, C. C., Carlomagno, A., Leyva, A., Bresque, M., Marmisolle, I., Quijano, C., Durán, R., Irigoín, F., Prieto-Echagüe, V., Vendelbo, M. H., Sotelo-Silveira, J. R., Chini, E. N., Badano, J. L., Calliari, A. J. & Escande, C. (2019). A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo. Scientific Reports, 9(1), Article 14381. https://doi.org/10.1038/s41598-019-50789-7

Tafvizizavareh, S., Shariati, P., Sharifirad, A., Maleki, B., Aliakbari, F., Christiansen, G. & Morshedi, D. (2019). Antibiotic hypersensitivity in MRSA induced by special protein aggregates. International Journal of Biological Macromolecules, 137, 528-536. https://doi.org/10.1016/j.ijbiomac.2019.07.001

Lindahl, L. M., Willerslev-Olsen, A., Gjerdrum, L. M. R., Nielsen, P. R., Blümel, E., Rittig, A. H., Celis, P., Herpers, B., Becker, J. C., Stausbøl-Grøn, B., Wasik, M. A., Gluud, M., Fredholm, S., Buus, T. B., Johansen, C., Nastasi, C., Peiffer, L., Kubat, L., Bzorek, M. ... Odum, N. (2019). Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma. Blood, 134(13), 1072-1083. https://doi.org/10.1182/blood.2018888107

Jensen, J. M. B., Møller, B. K., Thiel, S. & Hansen, A. T. (2019). Antibody Dependent Enhancement of Infections after High Dose Chemotherapy. Blood, 134(Supplement 1), 1047. https://doi.org/10.1182/blood-2019-122236

Brix, F. H., Møller, C. & Deleuran, B. (2019). Anti-interleukin 17 is a new possible treatment of patients with psoriatic arthritis. Ugeskrift for Læger, 181(4).

Andersen, T., Østgård, R. D., Aspari, M. P., Kragstrup, T. W., Glerup, H., Jurik, A. G., Johansen, C., Hvid, M. & Deleuran, B. W. (2019). Anti-tumor necrosis factor treatment increases both the Th17 and Th22 T helper subsets in spondyloarthritis. APMIS, 127(12), 789-796. https://doi.org/10.1111/apm.12994

Carlsen, R. K., Winther, S., Peters, C. D., Laugesen, E., Khatir, D. S., Bøtker, H. E., Bøttcher, M., Ivarsen, P., Svensson, M. & Buus, N. H. (2019). Aortic Calcification Affects Noninvasive Estimates of Central Blood Pressure in Patients with Severe Chronic Kidney Disease. Kidney and Blood Pressure Research, 44(4), 704-714. https://doi.org/10.1159/000501226

Tachibana, M., Holm, M.-L., Liu, C.-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. & Kanekiyo, T. (2019). APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1. Journal of Clinical Investigation, 129(3), 1272-1277. https://doi.org/10.1172/JCI124853

Mohammad-Beigi, H., Kjær, L., Eskandari, H., Aliakbari, F., Christiansen, G., Ruvo, G., L. Ward, J. & Otzen, D. (2019). A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants. Frontiers in Plant Science, 10(148), Article 148. https://doi.org/10.3389/fpls.2019.00148

Capoor, M. N., Birkenmaier, C., Wang, J. C., McDowell, A., Ahmed, F. S., Brüggemann, H., Coscia, E., Davies, D. G., Ohrt-Nissen, S., Raz, A., Ruzicka, F., Schmitz, J. E., Fischetti, V. A. & Slaby, O. (2019). A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue. European Spine Journal, 28(12), 2951-2971. https://doi.org/10.1007/s00586-019-06086-y

Berenji Ardestani, S., Matchkov, V., Eftedal, I. & Pedersen, M. (2019). A Single Simulated Heliox Dive Modifies Endothelial Function in the Vascular Wall of ApoE Knockout Male Rats More Than Females. Frontiers in Physiology, 10, Article 1342. https://doi.org/10.3389/fphys.2019.01342

Mikkelsen, S. A., Mogensen, L. S., Vilsen, B., Molday, R. S., Vestergaard, A. L. & Andersen, J. P. (2019). Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. Journal of Biological Chemistry, 294(15), 5970-5979. https://doi.org/10.1074/jbc.RA118.007240

Choi, K. W., Chen, C.-Y., Stein, M. B., Klimentidis, Y. C., Wang, M.-J., Koenen, K. C., Smoller, J. W. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study. JAMA Psychiatry, 76(4), 399-408. https://doi.org/10.1001/jamapsychiatry.2018.4175

Bordoni, L., Gutiérrez-Jiménez, E., Østergaard, L. & Frische, S. (2019). Association between Mild-Hyponatremia with Sustained Increased Intracranial Pressure in a New Animal Model and Assessment of the Effect of dDVAP during Severe Water Intoxication. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(1_supplement), Article 528.1. https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.528.1

Bauer, M., Glenn, T., Alda, M., Andreassen, O. A., Angelopoulos, E., Ardau, R., Ayhan, Y., Baethge, C., Bauer, R., Baune, B. T., Becerra-Palars, C., Bellivier, F., Belmaker, R. H., Berk, M., Bersudsky, Y., Bicakci, Ş., Birabwa-Oketcho, H., Bjella, T. D., Cabrera, J. ... Whybrow, P. C. (2019). Association between solar insolation and a history of suicide attempts in bipolar I disorder. Journal of Psychiatric Research, 113(June), 1-9. https://doi.org/10.1016/j.jpsychires.2019.03.001

Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T., Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Mors, O. ... Pedersen, C. B. (2019). Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia. JAMA network open, 2(11), Article e1914401. https://doi.org/10.1001/jamanetworkopen.2019.14401

Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, M., Børglum, A. D., Werge, T., Agerbo, E. & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium (2019). Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population. JAMA Psychiatry, 76(5), 516-525. https://doi.org/10.1001/jamapsychiatry.2018.4166

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T.-K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research Team, McIntosh, A. M. & Whalley, H. C. (2019). Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(1), 91-100. https://doi.org/10.1016/j.bpsc.2018.07.006

Fanouriakis, A., Kostopoulou, M., Aringer, M., Bajema, I. M., Boletis, J. N., Cervera, R., Doria, A. S., Gordon, C., Govoni, M., Houssiau, F., Jayne, D., Kouloumas, M., Kuhn, A., Larsen, J. L., Lerstrøm, K., Moroni, G., Mosca, M., Schneider, M., Smolen, J. ... Boumpas, D. (2019). A SYSTEMATIC LITERATURE REVIEW TO INFORM THE 2019 UPDATE OF THE EULAR RECOMMENDATIONS FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS. Abstract from EULAR 2019, Madrid, Spain.

Ljubas, J., Ovesen, T. & Rusan, M. (2019). A systematic review of phase II targeted therapy clinical trials in anaplastic thyroid cancer. Cancers, 11(7), Article 943. https://doi.org/10.3390/cancers11070943

Gudbergsson, J. M., Kostrikov, S., Johnsen, K. B., Fliedner, F. P., Stolberg, C. B., Humle, N., Hansen, A. E., Kristensen, B. W., Christiansen, G., Kjær, A., Andresen, T. L. & Duroux, M. (2019). A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response. Experimental Cell Research, 379(1), 73-82. https://doi.org/10.1016/j.yexcr.2019.03.031

Bauer, T. J., Gombocz, E., Krüger, M., Sahana, J., Corydon, T. J., Bauer, J., Infanger, M. & Grimm, D. (2019). Augmenting cancer cell proteomics with cellular images - a semantic approach to understand focal adhesion. Journal of Biomedical Informatics, 100, Article 103320. https://doi.org/10.1016/j.jbi.2019.103320

Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., Demontis, D., Kosmicki, J. A., Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., iPSYCH-Broad Consortium, Nordentoft, M., Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M. ... Daly, M. J. (2019). Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants. Nature Neuroscience, 22(12), 1961-1965. https://doi.org/10.1038/s41593-019-0527-8

Larsen, C. S., Christiansen, M. & Mogensen, T. H. (2019). Autosomal Dominant Hyper-IgE Syndrome Without Significantly Elevated IgE. Journal of Clinical Immunology, 39(8), 827-831. https://doi.org/10.1007/s10875-019-00683-8

Generation Scotland, & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). A validation of the diathesis-stress model for depression in Generation Scotland. Translational Psychiatry, 9(1), Article 25. https://doi.org/10.1038/s41398-018-0356-7

Najarzadeh, Z., Pedersen, J. N., Christiansen, G., Shojaosadati, S. A., Pedersen, J. S. & Otzen, D. E. (2019). Bacterial amphiphiles as amyloid inducers: Effect of Rhamnolipid and Lipopolysaccharide on FapC fibrillation. Biochimica et Biophysica Acta - Proteins and Proteomics, 1867(11), Article 140263. https://doi.org/10.1016/j.bbapap.2019.140263

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