Iervolino, A., Prosperi, F., De La Motte, L. R.
, Petrillo, F., Spagnuolo, M., D’Acierno, M., Siccardi, S., Perna, A. F.
, Christensen, B. M., Frische, S., Capasso, G. & Trepiccione, F. (2020).
Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway.
Scientific Reports,
10(1), Article 5708.
https://doi.org/10.1038/s41598-020-61882-7Legarth, C., Grimm, D., Krüger, M., Infanger, M.
& Wehland, M. (2020).
Potential Beneficial Effects of Vitamin D in Coronary Artery Disease.
Nutrients,
12(1), Article 99.
https://doi.org/10.3390/nu12010099
Holthof, L. C., van der Horst, H. J., van Hal-van Veen, S. E., Ruiter, R. W. J., Li, F., Buijze, M.
, Andersen, M. N., Yuan, H., de Bruijn, J., van de Donk, N. W. C. J., Lokhorst, H. M., Zweegman, S., Groen, R. W. J. & Mutis, T. (2020).
Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
Haematologica,
105(2), e80-e83.
https://doi.org/10.3324/haematol.2018.213314Andersen, C. U., Lassen, P. O., Usman, H. Q., Albertsen, N.
, Nielsen, L. P. & Andersen, S. (2020).
Prevalence of medication-related falls in 200 consecutive elderly patients with hip fractures: A cross-sectional study.
BMC Geriatrics,
20, Article 121.
https://doi.org/10.1186/s12877-020-01532-9
Lund, I. C. B., Becher, N., Christensen, R., Petersen, O. B., Steffensen, E. H., Vestergaard, E. M. & Vogel, I. (2020).
Prevalence of mosaicism in uncultured chorionic villus samples after chromosomal microarray and clinical outcome in pregnancies affected by confined placental mosaicism.
Prenatal Diagnosis,
40(2), 244-259.
https://doi.org/10.1002/pd.5584
Christensen, M. G., Johnsen, N., Skals, M., Hamilton, A. D. M., Rubak, P.
, Hvas, A. M. & Praetorius, H. (2020).
Prevention of P2 Receptor-Dependent Thrombocyte Activation by Pore-Forming Bacterial Toxins Improves Outcome in A Murine Model of Urosepsis.
International Journal of Molecular Sciences ,
21(16), 1-18. Article 5652.
https://doi.org/10.3390/ijms21165652
Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hansen, A. S., Krishnamurthy, A., Hørslev-Petersen, K., Hetland, M. L.
, Stengaard-Pedersen, K., Østergaard, M., Ørnbjerg, L. M., Junker, P., Sharpe, A. H., Freeman, G. J., Annamalai, L.
, Hvid, M., Moestrup, S. K., Hauge, E.-M., Catrina, A. I.
& Deleuran, B. (2020).
Programmed death ligand 2 - A link between inflammation and bone loss in rheumatoid arthritis.
Journal of Translational Autoimmunity,
3, Article 100028.
https://doi.org/10.1016/j.jtauto.2019.100028
Choi, K. W., Chen, C.-Y., Ursano, R. J., Sun, X., Jain, S., Kessler, R. C., Koenen, K. C., Wang, M.-J., Wynn, G. H., Campbell-Sills, L., Stein, M. B., Smoller, J. W. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2020).
Prospective study of polygenic risk, protective factors, and incident depression following combat deployment in US Army soldiers.
Psychological Medicine,
50(5), 737-745.
https://doi.org/10.1017/S0033291719000527Mogra, R., Saaid, R., Tooher, J.
, Pedersen, L., Kesby, G. & Hyett, J. (2020).
Prospective Validation of First-Trimester Ultrasound Characteristics as Predictive Tools for Twin-Twin Transfusion Syndrome and Selective Intrauterine Growth Restriction in Monochorionic Diamniotic Twin Pregnancies.
Fetal Diagnosis and Therapy,
47(4), 321-327.
https://doi.org/10.1159/000504049Poulsen, T. B. G., Karamehmedovic, A., Aboo, C., Jørgensen, M. M., Yu, X., Fang, X., Blackburn, J. M., Nielsen, C. H.
, Kragstrup, T. W. & Stensballe, A. (2020).
Protein array-based companion diagnostics in precision medicine.
Expert Review of Molecular Diagnostics,
20(12), 1183-1198.
https://doi.org/10.1080/14737159.2020.1857734Anker-Møller, T., Hvas, A.-M., Sunde, N., Thiel, S. & Troldborg, A. (2020).
Proteins of the Lectin Pathway of complement activation at the site of injury in subarachnoid hemorrhage compared with peripheral blood.
Brain and Behavior,
10(8), e01728. Article 01728.
https://doi.org/10.1002/brb3.1728
Birkelund, S., Bennike, T. B., Kastaniegaard, K., Lausen, M., Poulsen, T. B. G.
, Kragstrup, T. W., Deleuran, B. W., Christiansen, G. & Stensballe, A. (2020).
Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients.
Clinical Proteomics,
17(1), Article 29.
https://doi.org/10.1186/s12014-020-09292-9Ludvigsen, M., Thorlacius-Ussing, L., Vorum, H., Moyer, M. P.
, Stender, M. T., Thorlacius-Ussing, O.
& Honoré, B. (2020).
Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer.
International Journal of Molecular Sciences ,
21(10), Article 3466.
https://doi.org/10.3390/ijms21103466
Chen, M., Maimaitili, M., Habekost, M., Gill, K. P., Mermet-Joret, N., Nabavi, S., Febbraro, F. & Denham, M. (2020).
Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells.
Stem Cell Research,
48, Article 101945.
https://doi.org/10.1016/j.scr.2020.101945
Thisted, D. L. A., Østergaard, M. V., Pedersen, A. A., Pedersen, P. J., Lindsay, R. T., Murray, A. J., Fink, L. N., Pedersen, T. X., Secher, T.
, Johansen, T. T., Thrane, S. T., Skarsfeldt, T., Jelsing, J., Thomsen, M. B. & Zois, N. E. (2020).
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Scientific Reports,
10(1), Article 16130.
https://doi.org/10.1038/s41598-020-73046-8Pedersen, D. V., Rösner, T.
, Hansen, A. G., Andersen, K. R., Thiel, S., Andersen, G. R., Valerius, T.
& Laursen, N. S. (2020).
Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement.
Molecular Immunology,
124, 200-210.
https://doi.org/10.1016/j.molimm.2020.06.005
Rajkumar, A. P., Qvist, P., Donskov, J. G., Lazarus, R.
, Pallesen, J., Nava, N., Winther, G., Liebenberg, N., Cour, S. H. L., Paternoster, V., Fryland, T., Palmfeldt, J., Fejgin, K., Mørk, A.
, Nyegaard, M., Pakkenberg, B., Didriksen, M.
, Nyengaard, J. R., Wegener, G. ... Børglum, A. D. (2020).
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice.
Translational Psychiatry,
10, Article 239.
https://doi.org/10.1038/s41398-020-00914-2
Frederiksen, K., Krag, A. E., Larsen, J. B., Kiil, B. J., Thiel, S. & Hvas, A.-M. (2020).
Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery.
PLoS One,
15(4), Article e0230411.
https://doi.org/10.1371/journal.pone.0230411
Rajeeve, K., Vollmuth, N., Janaki-Raman, S., Wulff, T. F., Baluapuri, A., Dejure, F. R., Huber, C., Fink, J., Schmalhofer, M., Schmitz, W., Sivadasan, R., Wolf, E., Eisenreich, W., Schulze, A., Seibel, J. & Rudel, T. (2020).
Reprogramming of host glutamine metabolism during Chlamydia trachomatis infection and its key role in peptidoglycan synthesis.
Nature Microbiology,
5(11), 1390-1402.
https://doi.org/10.1038/s41564-020-0762-5
Nielsen, M. A., Lomholt, S., Mellemkjær, A., Andersen, M. N., Buckley, C. D.
& Kragstrup, T. W. (2020).
Responses to Cytokine Inhibitors Associated with Cellular Composition in Models of Immune‐Mediated Inflammatory Arthritis.
ACR Open Rheumatology,
2(1), 3-10.
https://doi.org/10.1002/acr2.11094
Jensen, M. H., Ketharanathan, B., Debrabant, B.
, Schwartz, O. S., Mikkelsen, R., Fugleholm, K., Poulsen, F. R., Jensen, T. S. R., Thaarup, L. V.
& Bergholt, B. (2020).
Response to letter regarding: embolization of the middle meningeal artery in patients with chronic subdural hematoma - a review and meta-analysis.
Acta Neurochirurgica,
162(9), Article 2031.
https://doi.org/10.1007/s00701-020-04393-8
Ferguson, S., Major, A. S., Sullivan, J. T., Bourke, S. D.
, Kelly, S. J., Perry, B. J. & Ronson, C. W. (2020).
Rhizobium leguminosarum bv. trifolii NodD2 Enhances Competitive Nodule Colonization in the Clover-Rhizobium Symbiosis.
Applied and Environmental Microbiology,
86(18), Article e01268.
https://doi.org/10.1128/AEM.01268-20
Lam, M., Awasthi, S., Watson, H. J., Goldstein, J., Panagiotaropoulou, G., Trubetskoy, V., Karlsson, R., Frei, O., Fan, C. C., De Witte, W., Mota, N. R., Mullins, N., Brügger, K., Lee, S. H., Wray, N. R., Skarabis, N., Huang, H., Neale, B., Daly, M. J. ... Ripke, S. (2020).
RICOPILI: Rapid Imputation for COnsortias PIpeLIne.
Bioinformatics (Oxford, England),
36(3), 930-933.
https://doi.org/10.1093/bioinformatics/btz633Vestergaard, S. V., Heide-Jørgensen, U., Haalen, H. V., James, G., Hedman, K.
, Birn, H., Thomsen, R. W. & Christiansen, C. F. (2020).
Risk of anemia in patients with newly identified chronic kidney disease – a population-based cohort study.
Clinical epidemiology,
12, 953-962.
https://doi.org/10.2147/CLEP.S259648
Wium-Andersen, I. K.
, Rungby, J., Jørgensen, M. B.
, Sandbæk, A., Osler, M. & Wium-Andersen, M. K. (2020).
Risk of dementia and cognitive dysfunction in individuals with diabetes or elevated blood glucose.
Epidemiology and Psychiatric Sciences,
29, Article e43.
https://doi.org/10.1017/S2045796019000374Jensen, M. H.
, Kjolby, M., Hejlesen, O., Jakobsen, P. E. & Vestergaard, P. (2020).
Risk of Major Adverse Cardiovascular Events, Severe Hypoglycemia, and All-Cause Mortality for Widely Used Antihyperglycemic Dual and Triple Therapies for Type 2 Diabetes Management: A Cohort Study of All Danish Users. Diabetes Care,
43(6), 1209-1218.
https://doi.org/10.2337/dc19-2535Veys, K., Fan, Z., Ghobrial, M., Bouché, A., García-Caballero, M., Vriens, K., Conchinha, N. V., Seuwen, A., Schlegel, F., Gorski, T., Crabbé, M., Gilardoni, P., Ardicoglu, R., Schaffenrath, J., Casteels, C., De Smet, G., Smolders, I., Van Laere, K., Abel, E. D. ... De Bock, K. (2020).
Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity.
Circulation Research,
127(4), 466-482.
https://doi.org/10.1161/CIRCRESAHA.119.316463Dalskov, L., Møhlenberg, M., Thyrsted, J., Blay-Cadanet, J., Poulsen, E. T., Folkersen, B. H., Skaarup, S. H., Olagnier, D., Reinert, L., Enghild, J. J., Hoffmann, H. J., Holm, C. K. & Hartmann, R. (2020).
SARS-CoV-2 evades immune detection in alveolar macrophages.
EMBO Reports,
21(12), Article e51252.
https://doi.org/10.15252/embr.202051252
Olagnier, D., Farahani, E., Thyrsted, J., Blay-Cadanet, J., Herengt, A., Idorn, M., Hait, A., Hernaez, B.
, Knudsen, A., Iversen, M. B., Schilling, M.
, Jørgensen, S. E., Thomsen, M., Reinert, L. S., Lappe, M., Hoang, H.-D., Gilchrist, V. H.
, Hansen, A. L., Ottosen, R. ... Holm, C. K. (2020).
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Nature Communications,
11(1), Article 4938.
https://doi.org/10.1038/s41467-020-18764-3
Sokołowska, A., Świerzko, A. S., Szala-Poździej, A., Augustynowicz-Kopeć, E., Kozińska, M., Niemiec, T., Błachnio, M., Borkowska-Tatar, D.
, Jensenius, J. C., Thiel, S., Dziadek, J. & Cedzyński, M. (2020).
Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis.
Immunobiology,
225(3), 151905. Article 151905.
https://doi.org/10.1016/j.imbio.2020.151905Sørensen, C. A., Olesen, C., Lisby, M., Enemark, U. & de Thurah, A. (2020).
Self-administration of medication during hospitalization – a randomized pilot study.
Pilot and Feasibility Studies,
6, Article 116.
https://doi.org/10.1186/s40814-020-00665-3
Marques de Menezes, E. G., Jang, K., George, A. F.
, Nyegaard, M., Neidleman, J., Inglis, H. C., Danesh, A., Deng, X., Afshari, A., Kim, Y. H., Billaud, J.-N., Marson, K., Pilcher, C. D., Pillai, S. K., Norris, P. J. & Roan, N. R. (2020).
Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract.
Journal of Virology,
94(16), Article e00525-20.
https://doi.org/10.1128/JVI.00525-20George, A. F., Jang, K. S.
, Nyegaard, M., Neidleman, J., Spitzer, T. L., Xie, G., Chen, J. C., Herzig, E.
, Laustsen, A., Marques de Menezes, E. G., Houshdaran, S., Pilcher, C. D., Norris, P. J.
, Jakobsen, M. R., Greene, W. C.
, Giudice, L. C. & Roan, N. R. (2020).
Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.
Human Reproduction,
35(3), 617-640.
https://doi.org/10.1093/humrep/deaa015Iena, F. M., Jul, J. B., Vegger, J. B., Lodberg, A., Thomsen, J. S., Brüel, A. & Lebeck, J. (2020).
Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver.
Frontiers in Endocrinology,
11, Article 577650.
https://doi.org/10.3389/fendo.2020.577650
Rovira, P.
, Demontis, D., Sánchez-Mora, C., Zayats, T., Klein, M., Mota, N. R., Weber, H., Garcia-Martínez, I., Pagerols, M., Vilar-Ribó, L., Arribas, L., Richarte, V., Corrales, M., Fadeuilhe, C., Bosch, R., Martin, G. E., Almos, P., Doyle, A. E., Grevet, E. H. ... 23andMe Research Team (2020).
Shared genetic background between children and adults with attention deficit/hyperactivity disorder.
Neuropsychopharmacology,
45(10), 1617-1626.
https://doi.org/10.1038/s41386-020-0664-5Adewuyi, E. O., Sapkota, Y., International Endogene Consortium (IEC), 23andMe Research Team, International Headache Genetics Consortium (IHGC), Auta, A., Yoshihara, K.
, Nyegaard, M., Griffiths, L. R., Montgomery, G. W., Chasman, D. I. & Nyholt, D. R. (2020).
Shared molecular genetic mechanisms underlie endometriosis and migraine comorbidity.
Genes,
11(3), Article 268.
https://doi.org/10.3390/genes11030268Hybel, T. E., Dietrichs, D.
, Sahana, J., Corydon, T. J., Nassef, M. Z.
, Wehland, M., Krüger, M.
, Magnusson, N. E., Bauer, J., Utpatel, K., Infanger, M.
, Grimm, D. & Kopp, S. (2020).
Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells.
International Journal of Molecular Sciences ,
21(4), Article E1263.
https://doi.org/10.3390/ijms21041263
Rohlenova, K., Goveia, J., García-Caballero, M., Subramanian, A.
, Kalucka, J., Treps, L., Falkenberg, K. D., de Rooij, L. P. M. H., Zheng, Y.
, Lin, L., Sokol, L., Teuwen, L.-A., Geldhof, V., Taverna, F., Pircher, A., Conradi, L.-C., Khan, S., Stegen, S., Panovska, D.
... Carmeliet, P. (2020).
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Cell Metabolism,
31(4), 862-877.e14.
https://doi.org/10.1016/j.cmet.2020.03.009Dumas, S. J., Meta, E., Borri, M., Goveia, J., Rohlenova, K., Conchinha, N. V., Falkenberg, K., Teuwen, L.-A., de Rooij, L.
, Kalucka, J., Chen, R., Khan, S., Taverna, F., Lu, W., Parys, M., De Legher, C., Vinckier, S., Karakach, T. K., Schoonjans, L.
... Carmeliet, P. (2020).
Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation.
Journal of the American Society of Nephrology : JASN,
31(1), 118-138.
https://doi.org/10.1681/ASN.2019080832Kalucka, J., de Rooij, L. P. M. H., Goveia, J., Rohlenova, K., Dumas, S. J., Meta, E., Conchinha, N. V., Taverna, F., Teuwen, L.-A., Veys, K., García-Caballero, M., Khan, S., Geldhof, V., Sokol, L., Chen, R., Treps, L., Borri, M., de Zeeuw, P., Dubois, C.
... Carmeliet, P. (2020).
Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
Cell,
180(4), 764-779.e20.
https://doi.org/10.1016/j.cell.2020.01.015
Juul-Madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, A. E., Vestergaard, B.
, Howard, K., Dehesa-Etxebeste, M.
, Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-Ramos, M. & Vorup-Jensen, T. (2020).
Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4.
Journal of Immunology,
204(5), 1345-1361.
https://doi.org/10.4049/jimmunol.1900494