Peer-reviewed publications

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Brent, M. B., Thomsen, J. S. & Brüel, A. (2021). Short-term glucocorticoid excess blunts abaloparatide-induced increase in femoral bone mass and strength in mice. Scientific Reports, 11(1), Article 12258. https://doi.org/10.1038/s41598-021-91729-8

Nielsen, J. E., Honoré, B., Vestergård, K., Maltesen, R. G., Christiansen, G., Bøge, A. U., Kristensen, S. R. & Pedersen, S. (2021). Shotgun-based proteomics of extracellular vesicles in Alzheimer's disease reveals biomarkers involved in immunological and coagulation pathways. Scientific Reports, 11(1), Article 18518. https://doi.org/10.1038/s41598-021-97969-y

Andersen, T. L., Delaisse, J. M., Thomsen, J. S. & Andreasen, C. M. (2021). Significance of Reversal-Resorption Phase in Bone Loss. In Osteoporotic Fracture and Systemic Skeletal Disorders: Mechanism, Assessment, and Treatment (pp. 101-110). Springer Nature. https://doi.org/10.1007/978-981-16-5613-2_7

Petersen, K. V., Selas, A., Hymøller, K. M., Mizielinski, K., Thorsager, M., Stougaard, M., Alonso, C., Palacios, F., Pérez-Pertejo, Y., Reguera, R. M., Balaña-Fouce, R., Knudsen, B. R. & Tesauro, C. (2021). Simple and fast DNA based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1. Pharmaceutics, 13(8), Article 1255. https://doi.org/10.3390/pharmaceutics13081255

Kyvsgaard, N., Mikkelsen, T. S., Als, T. D., Christensen, A. E., Corydon, T. J. & Herlin, T. (2021). Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis. Pediatric Rheumatology , 19(1), Article 51. https://doi.org/10.1186/s12969-021-00539-9

Pettersson, S., Edin, F., Hjelte, C., Scheinost, D., Wagner, S., Ekblom, B., Jessen, N., Madsen, K. & Andersson-Hall, U. (2021). Six Weeks of Aerobic Exercise in Untrained Men With Overweight/Obesity Improved Training Adaptations, Performance and Body Composition Independent of Oat/Potato or Milk Based Protein-Carbohydrate Drink Supplementation. Frontiers in Nutrition, 8, Article 617344. https://doi.org/10.3389/fnut.2021.617344

Jensen, M. L. N., Troldborg, A. M., Pfeiffer-Jensen, M. & Deleuran, B. (2021). Sjögrens syndrom. Ugeskrift for Læger, 183(31), Article V04210309.

Jakobsgaard, J. E., Andresen, J., de Paoli, F. V. & Vissing, K. (2021). Skeletal muscle phenotype signaling with ex vivo endurance-type dynamic contractions in rat muscle. Journal of applied physiology (Bethesda, Md. : 1985), 131(1), 45-55. https://doi.org/10.1152/japplphysiol.00107.2021

Leffers, H. B., Troldborg, A., Voss, A., Kristensen, S., Lindhardsen, J., Kumar, P., Linauskas, A., Juul, L., Krogh, N. S., Deleuran, B. W., Dreyer, L. & Jacobsen, S. (2021). Smoking associates with distinct clinical phenotypes in patients with systemic lupus erythematosus: a nationwide Danish cross-sectional study. Lupus Science and Medicine, 8(1), Article e000474. https://doi.org/10.1136/lupus-2021-000474

Choi, I., Beedholm, K., Dam, V. S., Bae, S.-H., Noble, D. J., Garraway, S. M., Aalkjær, C. & Boedtkjer, E. (2021). Sodium bicarbonate cotransporter NBCn1/Slc4a7 affects locomotor activity and hearing in mice. Behavioural Brain Research, 401, Article 113065. https://doi.org/10.1016/j.bbr.2020.113065

Nissen, S. K., Ferreira, S. A., Nielsen, M. C., Schulte, C., Shrivastava, K., Hennig, D., Etzerodt, A., Graversen, J. H., Berg, D., Maetzler, W., Panhelainen, A., Møller, H. J., Brockmann, K. & Romero-Ramos, M. (2021). Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease. Movement Disorders, 36(4), 963-976. https://doi.org/10.1002/mds.28424

Schmidt, V., Horváth, C., Dong, H., Blüher, M., Qvist, P., Wolfrum, C. & Willnow, T. E. (2021). SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat. The Journal of Cell Biology, 220(12), Article e202006058. https://doi.org/10.1083/jcb.202006058

Møller, P. L., Rohde, P. D., Winther, S., Breining, P., Nissen, L., Nykjær, A., Böttcher, M., Nyegaard, M. & Kjolby, M. (2021). Sortilin as a Biomarker for Cardiovascular Disease Revisited. Frontiers in Cardiovascular Medicine, 8, Article 652584. https://doi.org/10.3389/fcvm.2021.652584

Brent, M. B., Brüel, A. & Thomsen, J. S. (2021). Sparse dose-dependent difference in skeletal effects of short-term glucocorticoid excess in outbred Swiss mice. Endocrine and Metabolic Science, 5, Article 100144. https://doi.org/10.1016/j.endmts.2021.100114

Banki, E., Fisi, V., Moser, S., Wengi, A., Carrel, M., Loffing-Cueni, D., Penton, D., Kratschmar, D. V., Rizzo, L., Lienkamp, S., Odermatt, A., Rinschen, M. M. & Loffing, J. (2021). Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis. Kidney International, 100(4), 850-869. https://doi.org/10.1016/j.kint.2021.06.030

Brüner, M., Dige, A., Loft, A. G., Laurberg, T. B., Agnholt, J. S., Clemmensen, K., McInnes, I., Lories, R., Iversen, L., Hjuler, K. F. & Kragstrup, T. W. (2021). Spondylitis-psoriasis-enthesitis-enterocolitis-dactylitis-uveitis-peripheral synovitis (SPEED-UP) treatment. Autoimmunity Reviews, 20(2), Article 102731. https://doi.org/10.1016/j.autrev.2020.102731

Jørgensen, S. E., Al-Mousawi, A., Assing, K., Hartling, U., Grosen, D., Fisker, N., Nielsen, C., Jakobsen, M. A. & Mogensen, T. H. (2021). STK4 Deficiency Impairs Innate Immunity and Interferon Production Through Negative Regulation of TBK1-IRF3 Signaling. Journal of Clinical Immunology, 41(1), 109–124. https://doi.org/10.1007/s10875-020-00891-7

Silote, G. P., Gatto, M. C., Eskelund, A., Guimarães, F. S., Wegener, G. & Joca, S. R. L. (2021). Strain-, sex-, and time-dependent antidepressant-like effects of cannabidiol. Pharmaceuticals, 14(12), Article 1269. https://doi.org/10.3390/ph14121269

Mohamed, N. A., Hinge, M., Larsen, O. H., Sørensen, U. B. S., Uldbjerg, N. & Nejsum, L. N. (2021). Streptococcus agalactiae do not penetrate human chorioamniotic membranes in vitro but alter their biomechanical properties. Acta Obstetricia et Gynecologica Scandinavica, 100(10), 1814-1821. https://doi.org/10.1111/aogs.14232

Zhang, N., Kisiswa, L., Ramanujan, A., Li, Z., Sim, E. W., Tian, X., Yuan, W., Ibáñez, C. F. & Lin, Z. (2021). Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains. Journal of Biological Chemistry, 297(2), Article 100916. https://doi.org/10.1016/j.jbc.2021.100916

Lall, G. M., Larmuseau, M. H. D., Wetton, J. H., Batini, C., Hallast, P., Huszar, T. I., Zadik, D., Aase, S., Baker, T., Balaresque, P., Bodmer, W., Børglum, A. D., de Knijff, P., Dunn, H., Harding, S. E., Løvvik, H., Dupuy, B. M., Pamjav, H., Tillmar, A. O. ... Jobling, M. A. (2021). Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain. European Journal of Human Genetics, 29(3), 512-523. https://doi.org/10.1038/s41431-020-00747-z

Hansen, S., Askou, A. L., la Cour, M., Corydon, T. J. & Bek, T. (2021). Subretinal Saline Protects the Neuroretina From Thermic Damage During Laser Induction of Experimental Choroidal Neovascularization in Pigs. Translational vision science & technology, 10(7), Article 29. https://doi.org/10.1167/TVST.10.7.29

Matthiesen, C. L., Hu, L., Torslev, A. S., Poulsen, E. T., Larsen, U. G., Kjaer-Sorensen, K., Thomsen, J. S., Brüel, A., Enghild, J. J., Oxvig, C. & Petersen, S. V. (2021). Superoxide dismutase 3 is expressed in bone tissue and required for normal bone homeostasis and mineralization. Free Radical Biology and Medicine, 164, 399-409. https://doi.org/10.1016/j.freeradbiomed.2021.01.027

Monici, M., Cialdai, F., Bani, D., Bacci, S., Morbidelli, L., Norfini, A., Balsamo, M., van Loon, J., Grimm, D., Riwaldt, S., Coppola, G., Surdo, L., Ferranti, F. & Pantalone, D. (2021). Suture in Space: Preparation of an Experiment on the Healing of Sutured Wounds on Board the ISS. Proceedings of the International Astronautical Congress, IAC, A1.

Aalkjaer, C., Nilsson, H. & De Mey, J. G. R. (2021). Sympathetic and sensory-motor nerves in peripheral small arteries. Physiological Reviews, 101(2), 495-544. https://doi.org/10.1152/physrev.00007.2020

Zheng, T., Huang, J., Xiang, X., Li, S., Yu, J., Qu, K., Xu, Z., Han, P., Dong, Z., Liu, Y., Xu, F., Yang, H., Jäättelä, M., Luo, Y. & Liu, B. (2021). Systematical analysis reveals a strong cancer relevance of CREB1-regulated genes. Cancer Cell International, 21(1), Article 530. https://doi.org/10.1186/s12935-021-02224-z

Knudsen, S. S., Simard, J. F., Knudsen, J. S., Christensen, J., Laursen, T. M., Deleuran, B. W. & Bech, B. H. (2021). Systemic lupus erythematosus during pregnancy is not associated with school performance in offspring - A Danish population-based study. Lupus, 30(2), 228-237. https://doi.org/10.1177/0961203320973076

Holmgaard, A. B., Askou, A. L., Jensen, E. G., Alsing, S., Bak, R. O., Mikkelsen, J. G. & Corydon, T. J. (2021). Targeted Knockout of the Vegfa Gene in the Retina by Subretinal Injection of RNP Complexes Containing Cas9 Protein and Modified sgRNAs. Molecular Therapy, 29(1), 191-207. https://doi.org/10.1016/j.ymthe.2020.09.032

Jensen, T. I., Mikkelsen, N. S., Gao, Z., Foßelteder, J., Pabst, G., Axelgaard, E., Laustsen, A., König, S., Reinisch, A. & Bak, R. O. (2021). Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi. Genome Research, 31(11), 2120-2130. https://doi.org/10.1101/gr.275607.121

Silveira, K. M., Wegener, G. & Joca, S. R. L. (2021). Targeting 2-arachidonoylglycerol signalling in the neurobiology and treatment of depression. Basic & Clinical Pharmacology & Toxicology, 129(1), 3-14. https://doi.org/10.1111/bcpt.13595

Thomsen, M. K., Cai, H., Stoltze, I. C., Vendelbo, M., Wagner, E. F., Bakiri, L. & Thomsen, M. K. (2021). Targeting AP-1 transcription factors by CRISPR in the prostate. OncoTarget, 12(19), 1956-1961. https://doi.org/10.18632/oncotarget.27997

Yin, D., Ling, S., Wang, D., Dai, Y., Jiang, H., Zhou, X., Paludan, S. R., Hong, J. & Cai, Y. (2021). Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice. Nature Biotechnology, 39(5), 567-577. https://doi.org/10.1038/s41587-020-00781-8

M'kacher, R., Colicchio, B., Marquet, V., Borie, C., Najar, W., Hempel, W. M., Heidingsfelder, L., Oudrhiri, N., Al Jawhari, M., Wilhelm-Murer, N., Miguet, M., Dieterlen, A., Deschênes, G., Tabet, A.-C., Junker, S., Grynberg, M., Fenech, M., Bennaceur-Griscelli, A., Voisin, P. ... Yardin, C. (2021). Telomere aberrations, including telomere loss, doublets, and extreme shortening, are increased in patients with infertility. Fertility and Sterility, 115(1), 164-173. https://doi.org/10.1016/j.fertnstert.2020.07.005

Brent, M. B., Stoltenborg, F. E., Brüel, A. & Thomsen, J. S. (2021). Teriparatide and Abaloparatide Have a Similar Effect on Bone in Mice. Frontiers in Endocrinology, 12, Article 628994. https://doi.org/10.3389/fendo.2021.628994

Bayarri-Olmos, R., Johnsen, L. B., Idorn, M., Reinert, L. S., Rosbjerg, A., Vang, S., Hansen, C. B., Helgstrand, C., Bjelke, J. R., Bak-Thomsen, T., Paludan, S. R., Garred, P. & Skjoedt, M. O. (2021). The alpha/b.1.1.7 sars-cov-2 variant exhibits significantly higher affinity for ace-2 and requires lower inoculation doses to cause disease in k18-hace2 mice. eLife, 10, Article e70002. https://doi.org/10.7554/eLife.70002

Garvert, L., Baune, B. T., Berger, K., Boomsma, D. I., Breen, G., Greinacher, A., Hamilton, S. P., Levinson, D. F., Lewis, C. M., Lucae, S., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Mors, O., Müller-Myhsok, B., Penninx, B. W. J. H., Perlis, R. H., Pistis, G., Potash, J. B. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). The association between genetically determined ABO blood types and major depressive disorder. Psychiatry Research, 299, Article 113837. https://doi.org/10.1016/j.psychres.2021.113837

Jakobsen, M. M., Nygaard, R. H., Hojbjerg, J. A. & Larsen, J. B. (2021). The association between vitamin D status and overuse sport injuries: A systematic review and meta-analysis. Translational Sports Medicine, 4(5), 553-564. https://doi.org/10.1002/tsm2.269

Praetorius, H. (2021). The bacteria and the host: a story of purinergic signaling in urinary tract infections. American journal of physiology. Cell physiology, 321(1), C134-C146. https://doi.org/10.1152/ajpcell.00054.2021

Holmen Olofsson, G., Pedersen, S. R., Aehnlich, P., Svane, I. M., Idorn, M. & thor Straten, P. (2021). The capacity of CD4⁺ Vγ9Vδ2 T cells to kill cancer cells correlates with co-expression of CD56. Cytotherapy, 23(7), 582-589. https://doi.org/10.1016/j.jcyt.2021.02.003

Melnik, D., Krüger, M., Schulz, H., Kopp, S., Wehland, M., Bauer, J., Baselet, B., Vermeesen, R., Baatout, S., Corydon, T. J., Infanger, M. & Grimm, D. (2021). The cellbox-2 mission to the international space station: Thyroid cancer cells in space. International Journal of Molecular Sciences , 22(16), Article 8777. https://doi.org/10.3390/ijms22168777

Wu, A., Wolley, M. J., Wu, Q., Gordon, R. D., Fenton, R. A. & Stowasser, M. (2021). The Cl⁻/HCO₃⁻ exchanger pendrin is downregulated during oral co-administration of exogenous mineralocorticoid and KCl in patients with primary aldosteronism. Journal of Human Hypertension, 35(10), 837-848. https://doi.org/10.1038/s41371-020-00439-7

Berthelsen, M. F., Riedel, M., Cai, H., Skaarup, S. H., Alstrup, A. K. O., Dagnæs-Hansen, F., Luo, Y., Jensen, U. B., Hager, H., Liu, Y., Callesen, H., Vendelbo, M. H., Jakobsen, J. E. & Thomsen, M. K. (2021). The CRISPR/Cas9 Minipig—A Transgenic Minipig to Produce Specific Mutations in Designated Tissues. Cancers, 13(12), Article 3024. https://doi.org/10.3390/cancers13123024

Zhang, C., Li, C., Yang, L., Leng, L., Jovic, D., Wang, J., Fang, F., Li, G., Zhao, D., Li, X., Lin, L., Luo, Y., Bolund, L., Huang, J., Lin, G. & Xu, F. (2021). The Dynamic Changes of Transcription Factors During the Development Processes of Human Biparental and Uniparental Embryos. Frontiers in Cell and Developmental Biology, 9, Article 709498. https://doi.org/10.3389/fcell.2021.709498

Bulik, C. M., Thornton, L. M., Parker, R., Kennedy, H., Baker, J. H., MacDermod, C., Guintivano, J., Cleland, L., Miller, A. L., Harper, L., Larsen, J. T., Yilmaz, Z., Grove, J., Sullivan, P. F., Petersen, L. V., Jordan, J., Kennedy, M. A. & Martin, N. G. (2021). The Eating Disorders Genetics Initiative (EDGI): study protocol. BMC Psychiatry, 21(1), Article 234. https://doi.org/10.1186/s12888-021-03212-3

Hansen, J. S., Hansen, R. M., Petersen, T., Gustavsen, S., Oturai, A. B., Sellebjerg, F., Sædder, E. A., Kasch, H., Rasmussen, P. V., Finnerup, N. B. & Svendsen, K. B. (2021). The effect of cannabis-based medicine on neuropathic pain and spasticity in patients with multiple sclerosis and spinal cord injury: Study protocol of a national multicenter double-blinded, placebo-controlled trial. Brain sciences, 11(9), Article 1212. https://doi.org/10.3390/brainsci11091212

Baran, R., Grimm, D. G., Infanger, M. & Wehland, M. (2021). The Effect of Continuous Positive Airway Pressure Therapy on Obstructive Sleep Apnea-Related Hypertension. International Journal of Molecular Sciences (Online), 22(5), 1-14. Article 2300. https://doi.org/10.3390/ijms22052300

Bromer, F. D., Brent, M. B., Pedersen, M., Thomsen, J. S., Brüel, A. & Foldager, C. B. (2021). The Effect of Normobaric Intermittent Hypoxia Therapy on Bone in Normal and Disuse Osteopenic Mice. High Altitude Medicine and Biology, 22(2), 225-234. https://doi.org/10.1089/ham.2020.0164

Giannakopoulou, O., Lin, K., Meng, X., Su, M.-H., Kuo, P.-H., Peterson, R. E., Awasthi, S., Moscati, A., Coleman, J. R. I., Bass, N., Millwood, I. Y., Chen, Y., Chen, Z., Chen, H.-C., Lu, M.-L., Huang, M.-C., Chen, C.-H., Stahl, E. A., Loos, R. J. F. ... 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. JAMA Psychiatry, 78(11), 1258-1269. https://doi.org/10.1001/jamapsychiatry.2021.2099

Hansen, R. S., Thuesen, K. K., Bregnhøj, A., Moldovan, L. I., Kristensen, L. S., Grek, C. L., Ghatnekar, G. S., Iversen, L. & Johansen, C. (2021). The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes. Experimental Dermatology, 30(6), 773-781. https://doi.org/10.1111/exd.14302

Bernth Jensen, J. M., Skeldal, S., Petersen, M. S., Møller, B. K., Hoffmann, S., Jensenius, J. C., Sørensen, U. B. S. & Thiel, S. (2021). The human natural anti-αGal antibody targets common pathogens by broad-spectrum polyreactivity. Immunology, 162(4), 434-451. https://doi.org/10.1111/imm.13297

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Revised 21.08.2025