Marczenke, M., Sunaga-Franze, D. Y., Popp, O., Althaus, I. W., Sauer, S., Mertins, P., Christ, A., Allen, B. L.
& Willnow, T. E. (2021).
GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Development,
148(21).
https://doi.org/10.1242/dev.200080Grimm, E.
, Sardella, D., Bordoni, L., Willig, K., Bestvater, F.
, Schiessl, I. M. & Sandhoff, R. (2021).
Generation of a Clta-Reporter Mouse Model for in vivo imaging of Endocytosis.
The FASEB Journal,
35(S1).
https://doi.org/10.1096/fasebj.2021.35.s1.05385Cromer, M. K., Camarena, J., Martin, R. M., Lesch, B. J., Vakulskas, C. A., Bode, N. M., Kurgan, G., Collingwood, M. A., Rettig, G. R., Behlke, M. A., Lemgart, V. T., Zhang, Y., Goyal, A., Zhao, F., Ponce, E., Srifa, W.
, Bak, R. O., Uchida, N., Majeti, R. ... Porteus, M. H. (2021).
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells.
Nature Medicine,
27(4), 677-687.
https://doi.org/10.1038/s41591-021-01284-yPirastu, N., Cordioli, M., Nandakumar, P., Mignogna, G., Abdellaoui, A., Hollis, B., Kanai, M.
, Rajagopal, V. M., Parolo, P. D. B., Baya, N., Carey, C. E., Karjalainen, J.
, Als, T. D., Van der Zee, M. D., Day, F. R., Ong, K. K., Morisaki, T., de Geus, E., Bellocco, R. ... iPSYCH Consortium (2021).
Genetic analyses identify widespread sex-differential participation bias.
Nature Genetics,
53(5), 663-671.
https://doi.org/10.1038/s41588-021-00846-7Adewuyi, E. O., Mehta, D., Sapkota, Y., International Endogene Consortium (IEC), 23andMe Research Team, Auta, A., Yoshihara, K.
, Nyegaard, M., Griffiths, L. R., Montgomery, G. W., Chasman, D. I. & Nyholt, D. R. (2021).
Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality.
Human Genetics,
140(3), 529-552.
https://doi.org/10.1007/s00439-020-02223-6Brikell, I., Wimberley, T., Albiñana, C., Pedersen, E. M., Vilhjálmsson, B. J., Agerbo, E., Demontis, D., Børglum, A. D., Schork, A. J., LaBianca, S., Werge, T.
, Mors, O., Hougaard, D. M., Thapar, A.
, Mortensen, P. B. & Dalsgaard, S. (2021).
Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD.
American Journal of Psychiatry,
178(9), 854-864.
https://doi.org/10.1176/appi.ajp.2020.20121686
Havdahl, A., Niarchou, M.
, Starnawska, A., Uddin, M., Van Der Merwe, C. & Warrier, V. (2021).
Genetic contributions to autism spectrum disorder.
Psychological Medicine,
51(13), 2260-2273.
https://doi.org/10.1017/S0033291721000192Liu, X., Nudel, R., Thompson, W. K., Appadurai, V., Schork, A. J., Buil, A., Rasmussen, S., Allesøe, R. L., Werge, T.
, Mors, O., Børglum, A. D., Hougaard, D. M.
, Mortensen, P. B., Nordentoft, M. & Benros, M. E. (2021).
Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study.
Brain, Behavior, and Immunity,
91, 10-23.
https://doi.org/10.1016/j.bbi.2020.06.014Aarøe, L., Appadurai, V., Hansen, K. M., Schork, A. J., Werge, T.
, Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, M.
, Mortensen, P. B., Thompson, W. K., Buil, A.
, Agerbo, E. & Petersen, M. B. (2021).
Genetic predictors of educational attainment and intelligence test performance predict voter turnout.
Nature Human Behaviour,
5(2), 281-291.
https://doi.org/10.1038/s41562-020-00952-2
Thomsen, M. M., Tyrberg, T.
, Skaalum, K., Carter-Timofte, M., Freytag, M. R., Norberg, P., Helleberg, M.
, Storgaard, M., Nielsen, H., Bodilsen, J., Grahn, A.
& Mogensen, T. (2021).
Genetic variants and immune responses in a cohort of patients with varicella zoster virus encephalitis.
The Journal of Infectious Diseases,
224(12), 2122-2132.
https://doi.org/10.1093/infdis/jiab254
Wiebking, V., Lee, C. M., Mostrel, N., Lahiri, P.
, Bak, R., Bao, G., Roncarolo, M. G., Bertaina, A. & Porteus, M. H. (2021).
Genome editing of donor-derived T-cells to generate allogenic chimeric antigen receptor-modified T cells: Optimizing αβ T cell-depleted haploidentical hematopoietic stem cell transplantation.
Haematologica,
106(3), 847-858.
https://doi.org/10.3324/haematol.2019.233882Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M.
, Børglum, A. D., Nordentoft, M., Werge, T., Christiansen, M., Schmiegelow, K.
, Juhler, M., Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J. (2021).
Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci.
Child's Nervous System,
37(3), 819–830.
https://doi.org/10.1007/s00381-020-04946-3Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z.
, Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G. ... HUNT All-In Psychiatry (2021).
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
Nature Genetics,
53(6), 817-829.
https://doi.org/10.1038/s41588-021-00857-4Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., McMahon, F. J., Moebus, S., Hess, T., Buerfent, B. C. ... Schumacher, J. (2021).
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.
Molecular Psychiatry,
26(8), 4179-4190.
https://doi.org/10.1038/s41380-019-0590-2Burton, C. L., Lemire, M., Xiao, B., Corfield, E. C., Erdman, L., Bralten, J., Poelmans, G., Yu, D., Shaheen, S. M., Goodale, T., Sinopoli, V. M., Soreni, N., Hanna, G. L., Fitzgerald, K., Rosenberg, D., Nestadt, G., Paterson, A. D., Strug, L. J., Schachar, R. ... OCD Working Group of the Psychiatric Genomics Consortium (2021).
Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder.
Translational Psychiatry,
11(1), Article 91.
https://doi.org/10.1038/s41398-020-01121-9Jakobsen, T., Dahl, M., Dimopoulos, K., Grønbæk, K.
, Kjems, J. & Kristensen, L. S. (2021).
Genome-wide circular RNA expression patterns reflect resistance to immunomodulatory drugs in multiple myeloma cells.
Cancers,
13(3), Article 365.
https://doi.org/10.3390/cancers13030365
Salar-Vidal, L., Achermann, Y., Aguilera-Correa, J. J., Poehlein, A., Esteban, J.
, Brüggemann, H. & ESCMID Study Group for Implant-Associated Infections (ESGIAI) (2021).
Genomic analysis of Cutibacterium acnes strains isolated from prosthetic joint infections.
Microorganisms,
9(7), Article 1500.
https://doi.org/10.3390/microorganisms9071500Aloi, E., Guo, J. H., Guzzi, R., Jiang, R. W.
, Ladefoged, L. K., Marsh, D.
, Esmann, M., Bartucci, R.
& Fedosova, N. U. (2021).
Geometry and water accessibility of the inhibitor binding site of Na+-pump: Pulse- and CW-EPR study.
Biophysical Journal,
120(13), 2679-2690.
https://doi.org/10.1016/j.bpj.2021.05.018Ernst, M., Rogers, S., Lausten-Thomsen, U., Bjorkbom, A., Laursen, S. S., Courraud, J.
, Borglum, A., Nordentoft, M., Werge, T.
, Mortensen, P. B., Hougaard, D. M. & Cohen, A. S. (2021).
Gestational age-dependent development of the neonatal metabolome.
Pediatric Research,
89(6), 1396-1404.
https://doi.org/10.1038/s41390-020-01149-zArendt, L. H., Pedersen, L. H., Pedersen, L., Ovesen, P. G., Henriksen, T. B., Lindhard, M. S., Olsen, J., Sørensen, H. T. & Ramlau-Hansen, C. H. (2021).
Glycemic control in pregnancies complicated by pre-existing diabetes mellitus and congenital malformations: A danish population-based study.
Clinical epidemiology,
13, 615-626.
https://doi.org/10.2147/CLEP.S298748
Andersen, S. U., Chakraborty, T., Chen, W., Chen, X.-M., Chen, Y., Hansen, M., Huang, K., Hubner, C. A., Jensen, T. E.
, Jessen, N., Kaufmann, S. H. E., Lee, J.-Y., Li, B., Li, J., Li, J., Li, Q., Li, Y.
, Lindner, P., Liu, W.
... Rogov, V. (2021).
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
1.
Autophagy,
17(1), 1-382.
https://doi.org/10.1080/15548627.2020.1797280
Abramavicius, S., Petersen, A. G., Renaltan, N. S., Prat-Duran, J., Torregrossa, R.
, Stankevicius, E., Whiteman, M.
& Simonsen, U. (2021).
GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries.
Frontiers in Pharmacology,
12, Article 613989.
https://doi.org/10.3389/fphar.2021.613989
Baier, J. M., Hansen, S. B., Straszek, S. P. V., Pedersen, S. B. & Nielsen, L. P. (2021).
Håndtering af metaboliske bivirkninger af antipsykotika.
Ugeskrift for Læger, (183), Article V04210333.
Najarzadeh, Z., Zaman, M., Sereikaite, V., Strømgaard, K.
, Andreasen, M. & Otzen, D. E. (2021).
Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus.
The Journal of Biological Chemistry,
297(2), 100953. Article 100953.
https://doi.org/10.1016/j.jbc.2021.100953
Boldt, A. B. W., Oliveira-Toré, C. D. F., Kretzschmar, G. C., Weinschutz Mendes, H., Stinghen, S. T., Andrade, F. A., Bumiller-Bini, V., Gonçalves, L. B., Braga, A. C. D. M., Stahlke, E. V. R. S., Velavan, T. P.
, Thiel, S. & de Messias-Reason, I. J. T. (2021).
Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors.
Frontiers in Immunology,
11, Article 574457.
https://doi.org/10.3389/fimmu.2020.574457Bergström, P., Trybala, E., Eriksson, C. E., Johansson, M., Satir, T. M., Widéhn, S., Fruhwürth, S., Michno, W., Nazir, F. H., Hanrieder, J.
, Paludan, S. R., Agholme, L., Zetterberg, H. & Bergström, T. (2021).
Herpes simplex virus 1 and 2 infections during differentiation of human cortical neurons.
Viruses,
13(10), Article 2072.
https://doi.org/10.3390/v13102072Kortenoeven, M. L. A., Esteva-Font, C., Dimke, H.
, Poulsen, S. B., Murali, S. K. & Fenton, R. A. (2021).
High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter.
The Journal of Biological Chemistry,
297(2), Article 100915.
https://doi.org/10.1016/j.jbc.2021.100915
Mana, M. D., Hussey, A. M., Tzouanas, C. N., Imada, S., Barrera Millan, Y., Bahceci, D., Saiz, D. R., Webb, A. T., Lewis, C. A.
, Carmeliet, P., Mihaylova, M. M., Shalek, A. K. & Yilmaz, Ö. H. (2021).
High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity.
Cell Reports,
35(10), Article 109212.
https://doi.org/10.1016/j.celrep.2021.109212Schmidt, N. H., Svendsen, P., Albarrán-Juárez, J., Moestrup, S. K. & Bentzon, J. F. (2021).
High-fructose feeding does not induce steatosis or non-alcoholic fatty liver disease in pigs.
Scientific Reports,
11, Article 2807.
https://doi.org/10.1038/s41598-021-82208-1
Bengtsen, M. B., Knudsen, J. S., Bengtsen, M. B., Møller, N. & Thomsen, RW. (2021).
Hospitalization for hypoglycaemia in people with diabetes in Denmark, 1997-2017: Time trends in incidence and HbA1c and glucose-lowering drug use before and after hypoglycaemia.
Endocrinology, Diabetes & Metabolism,
4(3), Article e00227.
https://doi.org/10.1002/edm2.227
Ronit, A.
, Jørgensen, S. E., Roed, C., Eriksson, R., Iepsen, U. W., Plovsing, R. R.
, Storgaard, M., Gustafsson, F., Hansen, A. B. E.
& Mogensen, T. H. (2021).
Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome.
Frontiers in Immunology,
12, Article 718744.
https://doi.org/10.3389/fimmu.2021.718744Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G.
, Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H.
... Jessen, N. (2021).
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients.
Cell Metabolism,
33(11), 2201-2214.e10.
https://doi.org/10.1016/j.cmet.2021.10.001
Egedal, J. H., Xie, G., Packard, T. A.
, Laustsen, A., Neidleman, J., Georgiou, K., Pillai, S. K., Greene, W. C.
, Jakobsen, M. R. & Roan, N. R. (2021).
Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection.
Mucosal Immunology,
14(5), 1203-1213.
https://doi.org/10.1038/s41385-021-00409-3
Sunde, L., Singh, R., Ravn, K., Schelde, P.
, Hansen, E. S., Uldbjerg, N., Niemann, I. & Hatt, L. (2021).
Hydatidiform mole diagnostics using circulating gestational trophoblasts isolated from maternal blood.
Molecular Genetics & Genomic Medicine,
9(1), Article e1565.
https://doi.org/10.1002/mgg3.1565
Hudek, R., Brobeil, A.
, Brüggemann, H., Sommer, F., Gattenlöhner, S. & Gohlke, F. (2021).
Cutibacterium acnes is an intracellular and intra-articular commensal of the human shoulder joint.
Journal of Shoulder and Elbow Surgery,
30(1), 16-26.
https://doi.org/10.1016/j.jse.2020.04.020Jørgensen, C. S., Horsdal, H. T., Rajagopal, V. M., Grove, J., Als, T. D., Kamperis, K., Nyegaard, M., Walters, G. B., Eðvarðsson, V. Ö., Stefánsson, H., Nordentoft, M., Hougaard, D. M., Werge, T.
, Mors, O., Mortensen, P. B., Agerbo, E., Rittig, S., Stefánsson, K.
, Børglum, A. D. ... Christensen, J. H. (2021).
Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study.
The Lancet Child and Adolescent Health,
5(3), 201-209.
https://doi.org/10.1016/S2352-4642(20)30350-3
Vestergaard, S. V., Christiansen, C. F., Thomsen, R. W., Birn, H. & Heide-Jørgensen, U. (2021).
Identification of Patients with CKD in Medical Databases: A Comparison of Different Algorithms.
Clinical Journal of American Society of Nephrology. ,
16(4), 543-551.
https://doi.org/10.2215/CJN.15691020
Christensen, M. W., Keefe, D. L., Wang, F., Hansen, C. S., Chamani, I. J., Sommer, C.
, Nyegaard, M., Rohde, P. D.
, Nielsen, A. L., Bybjerg-Grauholm, J., Kesmodel, U. S.
, Knudsen, U. B., Kirkegaard, K. & Ingerslev, H. J. (2021).
Idiopathic early ovarian aging: is there a relation with premenopausal accelerated biological aging in young women with diminished response to ART? Journal of Assisted Reproduction and Genetics,
38(11), 3027–3038.
https://doi.org/10.1007/s10815-021-02326-7
Andersen, S. M., Fage, S., Rubak, S. L., Holm, M., Jensen, J. M. B., Mogensen, T. & Deleuran, M. (2021).
Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome Manifesting as Lymphocytic Interstitial Pneumonia and Treatment-Resistant Bullous Pemphigoid.
Pediatric, Allergy, Immunology, and Pulmonology,
34(2), 76-79.
https://doi.org/10.1089/ped.2020.1307
Bryniarski, M. A., Zhao, B., Chaves, L. D.
, Mikkelsen, J. H., Yee, B. M., Yacoub, R., Shen, S.
, Madsen, M. & Morris, M. E. (2021).
Immunoglobulin G Is a Novel Substrate for the Endocytic Protein Megalin.
The AAPS Journal,
23(2), Article 40.
https://doi.org/10.1208/s12248-021-00557-1Ammitzbøll, C., Bartels, L. E., Bøgh Andersen, J.
, Risbøl Vils, S., Elbaek Mistegård, C., Dahl Johannsen, A., Hermansen, M.-L. F.
, Kragh Thomsen, M., Erikstrup, C., Hauge, E.-M. & Troldborg, A. (2021).
Impaired Antibody Response to the BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine in Patients With Systemic Lupus Erythematosus and Rheumatoid Arthritis.
ACR Open Rheumatology,
3(9), 622-628.
https://doi.org/10.1002/acr2.11299
Berg, P., Svendsen, S. L., Hoang, T. T. L., Praetorius, H. A., Sørensen, M. V. & Leipziger, J. (2021).
Impaired renal HCO3- secretion in CFTR deficient mice causes metabolic alkalosis during chronic base-loading.
Acta Physiologica,
231(3), Article e13591.
https://doi.org/10.1111/apha.13591
Paternoster, V., Edhager, A. V., Qvist, P., Donskov, J. G., Shliaha, P., Jensen, O. N.
, Mors, O., Nielsen, A. L., Børglum, A. D., Palmfeldt, J. & Christensen, J. H. (2021).
Inactivation of the Schizophrenia-associated BRD1 gene in Brain Causes Failure-to-thrive, Seizure Susceptibility and Abnormal Histone H3 Acetylation and N-tail Clipping.
Molecular Neurobiology,
58(9), 4495-4505.
https://doi.org/10.1007/s12035-021-02432-8
Basse, A. L., Agerholm, M.
, Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M.
, Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S. ... Treebak, J. T. (2021).
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity.
Molecular Metabolism,
53, Article 101271.
https://doi.org/10.1016/j.molmet.2021.101271Media, A. S., Christensen, T. D., Katballe, N., Pilegaard, H. K. & de Paoli, F. V. (2021).
Incidence and severity of surgical complications after pectus excavatum bar removal.
Interactive Cardiovascular and Thoracic Surgery,
33(2), 237-241.
https://doi.org/10.1093/icvts/ivab077