Peer-reviewed publications

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Rosenbaek, L., Petrillo, F., Van Bemmelen, M., Staub, O., Murali, S. & Fenton, R. (2022). The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter (NCC) but is not required for a potassium-induced reduction of NCC expression. The FASEB Journal, 36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.0R831

Rosenbaek, L. L., Petrillo, F., van Bemmelen, M. X., Staub, O., Murali, S. K. & Fenton, R. A. (2022). The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression. Frontiers in Physiology, 13, Article 971251. https://doi.org/10.3389/fphys.2022.971251

Elmholt, S. B., Hede, K. C., Christensen, B. B., Thomsen, J. S. & Lind, M. (2022). The Effect of Bone Marrow Stimulation for Cartilage Repair on the Subchondral Bone Plate. Cartilage, 13(1). https://doi.org/10.1177/19476035221074011

Ahring, K. K., Dagnæs-Hansen, F., Brüel, A., Christensen, M., Jensen, E., Jensen, T. G., Johannsen, M., Johansen, K. S., Lund, A. M., Madsen, J. G., Brøndum-Nielsen, K., Pedersen, M., Sørensen, L. K., Kjolby, M. & Møller, L. B. (2022). The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model. PLoS One, 17(1), Article e0261150. https://doi.org/10.1371/journal.pone.0261150

Kristensen, L. S., Jakobsen, T., Hager, H. & Kjems, J. (2022). The emerging roles of circRNAs in cancer and oncology. Nature Reviews. Clinical Oncology, 19(3), 188-206. https://doi.org/10.1038/s41571-021-00585-y

Voss, L. F., Howarth, A. J., Wittenborn, T. R., Hummelgaard, S., Juul-Madsen, K., Kastberg, K. S., Pedersen, M. K., Jensen, L., Papanastasiou, A. D., Vorup-Jensen, T., Weyer, K. & Degn, S. E. (2022). The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus. Frontiers in Immunology, 13, Article 1021370. https://doi.org/10.3389/fimmu.2022.1021370

Wigdor, E. M., Weiner, D. J., Grove, J., Fu, J. M., Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M., Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022). The female protective effect against autism spectrum disorder. Cell Genomics, 2(6), Article 100134. https://doi.org/10.1016/j.xgen.2022.100134

Grimm, D., Schulz, H., Krüger, M., Cortés-Sánchez, J. L., Egli, M., Kraus, A., Sahana, J., Corydon, T. J., Hemmersbach, R., Wise, P. M., Infanger, M. & Wehland, M. (2022). The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model. International Journal of Molecular Sciences , 23(6), Article 3073. https://doi.org/10.3390/ijms23063073

Mahjani, B., Klei, L., Mattheisen, M., Halvorsen, M. W., Reichenberg, A., Roeder, K., Pedersen, N. L., Boberg, J., de Schipper, E., Bulik, C. M., Landén, M., Fundín, B., Mataix-Cols, D., Sandin, S., Hultman, C. M., Crowley, J. J., Buxbaum, J. D., Rück, C., Devlin, B. & Grice, D. E. (2022). The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum. American Journal of Psychiatry, 179(3), 216-225. https://doi.org/10.1176/appi.ajp.2021.21010101

Arjmand, S., Landau, A. M., Varastehmoradi, B., Andreatini, R., Joca, S. & Wegener, G. (2022). The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants. Molecular Psychiatry, 27(8), 3138–3149 . https://doi.org/10.1038/s41380-022-01598-4

Kriegenburg, F., Huiting, W., van Buuren-Broek, F., Zwilling, E., Hardenberg, R., Mari, M. C., Kraft, C. & Reggiori, F. M. (2022). The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy. Autophagy Reports, 1(1), 345-367. https://doi.org/10.1080/27694127.2022.2104781

Mogensen, E. H., Poulsen, E. T., Thøgersen, I. B., Yamamoto, K., Brüel, A. & Enghild, J. J. (2022). The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea. Experimental Eye Research, 219, Article 109081. https://doi.org/10.1016/j.exer.2022.109081

van Soldt, B. J., Wang, T., Filogonio, R. & Danielsen, C. C. (2022). The mechanical and morphological properties of systemic and pulmonary arteries differ in the Madagascar ground boa, a snake without ventricular pressure separation. Journal of Experimental Biology, 225(13), Article jeb244419. https://doi.org/10.1242/jeb.244419

Reggiori, F. M., Boya, P., da Costa, D., Elazar, Z., Eskelinen, E.-L., Farrés, J., Guettler, S., Kraft, C., Jungbluth, H., Martinez, A., Morel, E., Pless, O., Proikas-Cezanne, T. & Simonsen, A. (2022). The mechanism of Macroautophagy: The movie. Autophagy Reports, 1(1), 414-417. https://doi.org/10.1080/27694127.2022.2096115

Rognant, S., Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjaer, C., Jepps, T. A. & Matchkov, V. V. (2022). The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells. Frontiers in Physiology, 13, 1007340. Article 1007340. https://doi.org/10.3389/fphys.2022.1007340

Fruergaard, M. U., Dach, I., Andersen, J. L., Ozol, M., Shasavar, A., Quistgaard, E. M. H., Poulsen, H., Fedosova, N. & Nissen, P. (2022). The Na,K-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. Journal of Biological Chemistry, 298(9), Article 102317. https://doi.org/10.1016/j.jbc.2022.102317

Laustsen, M. M., Nørgaard, M., Lam, M. Q., Koefoed-Nielsen, P. & Staunstrup, N. H. (2022). The novel HLA class I allele, HLA-B*14:110, identified by next-generation sequencing. HLA, 100(5), 520-522. https://doi.org/10.1111/tan.14721

Chernyakov, D., Fischer, A., Brandau, M., Petrillo, F., Fenton, R. A. & Edemir, B. (2022). The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression. Scientific Reports, 12(1), Article 20304. https://doi.org/10.1038/s41598-022-24237-y

Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022). The presence of interferon affects the progression of non-alcoholic fatty liver disease. Genes and Immunity, 23(5), 157–165. https://doi.org/10.1038/s41435-022-00176-6

Hennings, V., Thörn, K., Albinsson, S., Lingblom, C., Andersson, K., Andersson, C., Järbur, K., Pullerits, R., Idorn, M., Paludan, S. R., Eriksson, K. & Wennerås, C. (2022). The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from COVID-19. European Journal of Immunology, 52(5), 800-809. https://doi.org/10.1002/eji.202149655

Engbjerg, J. S., Costanzo, V., Sardella, D., Bordoni, L., Jakobsen, S., D'Apolito, L., Frøkiær, J., Trepiccione, F., Capasso, G. & Frische, S. (2022). The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo. Molecular Imaging, 2022, Article 7908357. https://doi.org/10.1155/2022/7908357

Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hørslev-Pedersen, K., Hetland, M. L., Stengaard-Pedersen, K., Østergaard, M., Ørnbjerg, L., Junker, P., Sharpe, A. H., Freeman, G. J., Hvid, M., Moestrup, S. K., Hauge, E. M. & Deleuran, B. (2022). The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings. Frontiers in Immunology, 13, Article 773946. https://doi.org/10.3389/fimmu.2022.773946

Paternoster, V., Cömert, C., Kirk, L. S., la Cour, S. H., Fryland, T., Fernandez-Guerra, P., Stougaard, M., Nyengaard, J. R., Qvist, P., Bross, P., Børglum, A. D. & Christensen, J. H. (2022). The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation. Translational Psychiatry, 12(1), Article 319. https://doi.org/10.1038/s41398-022-02053-2

Julander, J. G., Anderson, N., Haese, N., Andoh, T., Streblow, D. N., Cortez, P., Carter, K., Marniquet, X., Watson, H. & Mandron, M. (2022). Therapeutic and prophylactic treatment with a virus-specific antibody is highly effective in rodent models of Chikungunya infection and disease. Antiviral Research, 202, Article 105295. https://doi.org/10.1016/j.antiviral.2022.105295

Manry, J., Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., de Prost, N., Tandjaoui-Lambiotte, Y. ... CoV-Contact Cohort (2022). The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies. Proceedings of the National Academy of Sciences (PNAS), 119(21), Article e2200413119. https://doi.org/10.1073/pnas.2200413119

Yilmaz, Z., Larsen, J. T., Nissen, J. B., Crowley, J. J., Mattheisen, M., Bulik, C. M. & Petersen, L. V. (2022). The role of early-life family composition and parental socio-economic status as risk factors for obsessive-compulsive disorder in a Danish national cohort. Journal of Psychiatric Research, 149, 18-27. https://doi.org/10.1016/j.jpsychires.2022.02.004

Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A., Lassen, T. R., Jørgensen, M., Bæk, R., Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M. ... Drasbek, K. R. (2022). The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance. International Journal of Molecular Sciences , 23(6), Article 3334. https://doi.org/10.3390/ijms23063334

Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F. ... Nyegaard, M. (2022). The sequences of 150,119 genomes in the UK Biobank. Nature, 607, 732-740. https://doi.org/10.1038/s41586-022-04965-x

Li, C., Zhang, Y., Leng, L., Pan, X., Zhao, D., Li, X., Huang, J., Bolund, L., Lin, G., Luo, Y. & Xu, F. (2022). The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic development. Frontiers in Cell and Developmental Biology, 10, Article 1020490. https://doi.org/10.3389/fcell.2022.1020490

Boedtkjer, E. & Aalkjær, C. (2022). The solution to bicarbonate. American Journal of Physiology: Heart and Circulatory Physiology, 322(4), H685-H686. https://doi.org/10.1152/ajpheart.00057.2022

Casares, L., Moreno, R., Ali, K. X., Higgins, M., Dayalan Naidu, S., Neill, G., Cassin, L., Kiib, A. E., Svenningsen, E. B., Minassi, A., Honda, T., Poulsen, T. B., Wiel, C., Sayin, V. I., Dinkova-Kostova, A. T., Olagnier, D. & de la Vega, L. (2022). The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity. Redox Biology, 51, Article 102291. https://doi.org/10.1016/j.redox.2022.102291

Tabula Sapiens Consortium* (2022). The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science (New York, N.Y.), 376(6594), eabl4896. Article abl4896. https://doi.org/10.1126/science.abl4896

Bendl, J., Hauberg, M. E., Girdhar, K., Im, E., Vicari, J. M., Rahman, S., Fernando, M. B., Townsley, K. G., Dong, P., Misir, R., Kleopoulos, S. P., Reach, S. M., Apontes, P., Zeng, B., Zhang, W., Voloudakis, G., Brennand, K. J., Nixon, R. A., Haroutunian, V. ... Roussos, P. (2022). The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease. Nature Neuroscience, 25(10), 1366-1378. https://doi.org/10.1038/s41593-022-01166-7

Hansen, E. K. B., Fredsøe, J. H., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S. & Sørensen, K. D. (2022). The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. Genome Medicine, 14(1), Article 8. https://doi.org/10.1186/s13073-021-01009-3

Valsecchi, W. M., Faraj, S. E., Cerf, N. T., Fedosova, N. U. & Montes, M. R. (2022). The transported cations impose differences in the thermostability of the gastric H,K-ATPase. A kinetic analysis. Biochimica et biophysica acta - Biomembranes, 1864(11), Article 184006. https://doi.org/10.1016/j.bbamem.2022.184006

Dietrichs, D., Grimm, D., Sahana, J., Melnik, D., Corydon, T. J., Wehland, M., Krüger, M., Vermeesen, R., Baselet, B., Baatout, S., Hybel, T. E., Kahlert, S., Schulz, H., Infanger, M. & Kopp, S. (2022). Three-Dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity. Frontiers in Cell and Developmental Biology, 10, Article 841017. https://doi.org/10.3389/fcell.2022.841017

Lauritzen, E. S., Kampmann, U., Pedersen, M. G. B., Christensen, L.-L., Jessen, N., Møller, N. & Støy, J. (2022). Three months of melatonin treatment reduces insulin sensitivity in patients with type 2 diabetes - a randomized placebo-controlled crossover trial. Journal of Pineal Research, 73(1), Article e12809. https://doi.org/10.1111/jpi.12809

Troldborg, A., Thomsen, M. K., Bartels, L. E., Andersen, J. B., Vils, S. R., Mistegaard, C. E., Johannsen, A. D., Hermansen, M.-L. F., Mikkelsen, S., Erikstrup, C., Hauge, E.-M. & Ammitzbøll, C. (2022). Time since rituximab treatment is essential for developing a humoral response to COVID-19 mRNA vaccines in patients with rheumatic diseases. The Journal of Rheumatology, 49(6), 644-649. https://doi.org/10.3899/jrheum.211152

Duarte-Silva, E., Oriá, A. C., Mendonça, I. P., de Melo, M. G., Paiva, I. H. R., Maes, M., Joca, S. R. L. & Peixoto, C. A. (2022). Tiny in size, big in impact: Extracellular vesicles as modulators of mood, anxiety and neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews, 135, Article 104582. https://doi.org/10.1016/j.neubiorev.2022.104582

Guan, X., Zhang, B. & Sun, L. (2022). TNFR2 is a regulatory target of pol-miR-194a and promotes the antibacterial immunity of Japanese flounder Paralichthys olivaceus. Developmental and Comparative Immunology, 135, Article 104477. https://doi.org/10.1016/j.dci.2022.104477

Kostanjšek, R., Diderichsen, B., Recknagel, H., Gunde-Cimerman, N., Gostinčar, C., Fan, G., Kordiš, D., Trontelj, P., Jiang, H., Bolund, L. & Luo, Y. (2022). Toward the massive genome of Proteus anguinus-illuminating longevity, regeneration, convergent evolution, and metabolic disorders. Annals of the New York Academy of Sciences, 1507(1), 5-11. https://doi.org/10.1111/nyas.14686

Grimm, D. & Hemmersbach, R. (2022). Translation from Microgravity Research to Earth Application. International Journal of Molecular Sciences , 23(19), Article 10995. https://doi.org/10.3390/ijms231910995

Christensen, D. S., Ahrenfeldt, J., Sokač, M., Kisistók, J., Thomsen, M. K., Maretty, L., McGranahan, N. & Birkbak, N. J. (2022). Treatment Represents a Key Driver of Metastatic Cancer Evolution. Cancer Research, 82(16), 2918-2927. https://doi.org/10.1158/0008-5472.CAN-22-0562

Petersen, A., Lind, P. C., Mogensen, S., Jensen, A.-S. B., Granfeldt, A. & Simonsen, U. (2022). Treatment with senicapoc, a K _Ca3.1 channel blocker, alleviates hypoxaemia in a mouse model of acute respiratory distress syndrome. British Journal of Pharmacology, 179(10), 2175-2192. https://doi.org/10.1111/bph.15704

Pose, E., Solà, E., Lozano, J. J., Juanola, A., Sidorova, J., Zaccherini, G., de Wit, K., Uschner, F., Tonon, M., Kazankov, K., Jiménez, C., Campion, D., Napoleone, L., Ma, A. T., Carol, M., Morales-Ruiz, M., Alessandria, C., Beuers, U., Caraceni, P. ... investigators of the LIVERHOPE Consortium (2022). Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis. Hepatology Communications, 6(5), 1100-1112. https://doi.org/10.1002/hep4.1881

Sørensen, A. S., Andersen, M. N., Juul-Madsen, K., Broksø, A. D., Skejø, C., Schmidt, H., Vorup-Jensen, T. & Kragstrup, T. W. (2022). Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis. Arthritis Research and Therapy, 24(1), Article 43. https://doi.org/10.1186/s13075-022-02737-6

Enemark, M. B., Hybel, T. E., Madsen, C., Lauridsen, K. L., Honoré, B., Plesner, T. L., Hamilton-Dutoit, S., D’amore, F. & Ludvigsen, M. (2022). Tumor-Tissue Expression of the Hyaluronic Acid Receptor RHAMM Predicts Histological Transformation in Follicular Lymphoma Patients. Cancers, 14(5), Article 1316. https://doi.org/10.3390/cancers14051316

Cuypers, A., Truong, A. C. K., Becker, L. M., Saavedra-García, P. & Carmeliet, P. (2022). Tumor vessel co-option: The past & the future. Frontiers in Oncology, 12, Article 965277. https://doi.org/10.3389/fonc.2022.965277

Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A., Otzen, D., Klenerman, D., Matthews, S., Linse, S., Andreasen, M. & Knowles, T. P. J. (2022). Uncovering the universality of self-replication in protein aggregation and its link to disease. Science Advances, 8(32), Article eabn6831. https://doi.org/10.1126/sciadv.abn6831

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