Lobato-Moreno, S., Yildiz, U., Claringbould, A., Servaas, N. H., Vlachou, E. P., Arnold, C., Bauersachs, H. G., Campos-Fornés, V., Kim, M., Berest, I., Prummel, K. D.
, Noh, K. M., Marttinen, M. & Zaugg, J. B. (2025).
Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics.
Nature Methods,
22(6), 1213-1225. Article 5941.
https://doi.org/10.1038/s41592-025-02700-8
Nitulescu, A. M., Du, W., Glaser, V., Kath, J., Aird, E. J., Cullot, G., Greensmith, R.
, Mikkelsen, N. S., Stein, M.
, Bak, R. O., Kaminski, M., Corn, J. E. & Wagner, D. L. (2025).
Single-stranded HDR templates with truncated Cas12a-binding sequences improve knock-in efficiencies in primary human T cells.
Molecular Therapy Nucleic Acids,
36(2), Article 102568.
https://doi.org/10.1016/j.omtn.2025.102568
Farhat, L. C., Isomura, K., Fernández de la Cruz, L., Sidorchuk, A., Kuja-Halkola, R.
, Brikell, I., Chang, Z., D’Onofrio, B. M., Larsson, H., Lichtenstein, P. & Mataix-Cols, D. (2025).
Sociodemographic and clinical characteristics of 1,234 individuals diagnosed with trichotillomania in the Swedish National Patient Register.
Scientific Reports,
15(1), Article 10396.
https://doi.org/10.1038/s41598-025-95416-w
Lauridsen, K. M., Møller, H. J., Kristensen, M. W., Fristrup, N., Donskov, F., Hokland, M. & Andersen, M. N. (2025).
Soluble CD206 in metastatic renal cell carcinoma: Relation to clinical–biochemical parameters and patient outcome.
International Journal of Cancer,
156(4), 875-885.
https://doi.org/10.1002/ijc.35194
Fog, M. H., Hubert, V., Sanglar, C., Martin, M., Hristovska, I., Karpati, S., Lerouge, F., Parola, S., Pascual, O., Wiart, M., Lancelin, J.-M.
, Vorup-Jensen, T. & Guillière, F. (2025).
Solution-based studies on the contact between the complement receptor 3 ligand-binding domain and simvastatin.
Biochimica et Biophysica Acta - Proteins and Proteomics,
1873(6), Article 141096.
https://doi.org/10.1016/j.bbapap.2025.141096
Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E.
, Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C.
, Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R.
, Nykjær, A. & Matchkov, V. (2025).
SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling.
Acta Physiologica (Print),
241(6), Article e70052.
https://doi.org/10.1111/apha.70052
Sushentsev, N., Hamm, G., Manavaki, R., McLean, M. A., Birchall, J., Soloviev, D., Lewis, D. Y., Aloj, L., Flint, L., Zakirov, A.
, Mills, I. G., Gnanapragasam, V. J., Warren, A. Y., Barry, S. T., Goodwin, R. J. A., Gallagher, F. A. & Barrett, T. (2025).
Spatial metabolomics informs the use of clinical imaging for improved detection of cribriform prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America,
122(26), Article e2502423122.
https://doi.org/10.1073/pnas.2502423122
Lv, W., Zeng, Y., Li, C., Liang, Y., Tao, H., Zhu, Y., Sui, X., Li, Y., Jiang, S., Gao, Q., Rodriguez-Fos, E., Prasad, G., Wang, Y., Zhou, R., Xu, Z., Pan, X., Chen, L.
, Xiang, X., Teng, H. ... Han, P. (2025).
Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment.
Cancer Discovery,
15(6), 1225-1246.
https://doi.org/10.1158/2159-8290.CD-24-1532
Hansen, L. M. B., Dam, V. S., Guldbrandsen, H. Ø., Staehr, C., Pedersen, T. M., Kalucka, J. M., Beck, H. C.
, Postnov, D., Lin, L. & Matchkov, V. (2025).
Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations.
Stroke,
56(4), 1036-1047.
https://doi.org/10.1161/STROKEAHA.124.048085
Entezari, S., Thygesen, M. M., Staehr, C., Melnikova, E., Skov, M., Rajanathan, R., Rasmussen, M., Rasmussen, M. M. & Matchkov, V. V. (2025).
Spinal cord blood flow elevation with systemic vasopressor noradrenaline is partly mediated by vasodilation of spinal arteries due to reduced expression of alpha adrenoreceptors.
The spine journal : official journal of the North American Spine Society,
25(3), 609-619.
https://doi.org/10.1016/j.spinee.2024.11.010
Entezari, S., Thygesen, M., Staehr, C., Skov, M., Rajanathan, R., Melnikova, E., Rasmussen, M., Rasmussen, M. M. & Matchkov, V. (2025).
Spinal cord blood flow elevation with systemic vasopressor noradrenaline is partly mediated by vasodilation of spinal arteries due to reduced expression of alpha adrenoreceptors. Abstract from European Neurotrauma Summit 2025, Lund, Sweden.
Jensen, T. S., Laursen, M. F., Schort, L., Banasik, A. J., Agger, R.
, Jakobsen, M. R. & Kofod-Olsen, E. (2025).
STING and Nonnecroptotic MLKL-Mediated Mechanisms Improve Dendritic Cell Maturation and Killing of Cancer Cells.
European Journal of Immunology,
55(9), Article e70044.
https://doi.org/10.1002/eji.70044
Zhang, B.-C., Pedersen, A., Reinert, L. S., Li, Y.
, Narita, R., Idorn, M., Hu, L., Skouboe, M. K., Li, S.
, Maimaitili, M., Ding, X., Cong, Y., Zhao, J., Frémond, M.-L.
, Mikkelsen, K., Gao, Z., Huang, J.-R.
, Thomsen, E. A., Mikkelsen, J. H. ... Paludan, S. R. (2025).
STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor.
Nature Immunology,
26(11), 1916-1930.
https://doi.org/10.1038/s41590-025-02283-8
Bjørndal, L. D., Chen, Y., Lu, D.
, Brikell, I., Kuja-Halkola, R., D'Onofrio, B. M., Lundin, A. H., Lichtenstein, P., Larsson, H., Daníelsdóttir, H. B., Fall, K., Valdimarsdóttir, U. A. & Fang, F. (2025).
Stress Resilience and Risk of Psychiatric Disorders After Childhood Bereavement.
JAMA network open,
8(7), Article e2519706.
https://doi.org/10.1001/jamanetworkopen.2025.19706
Holst Hansen, K., Golcuk, M., Byeon, C. H., Tunc, A., Buhl Plechinger, E., Dueholm, M. K. D., Conway, J. F.
, Andreasen, M., Gur, M. & Akbey, Ü. (2025).
Structural Basis of Pseudomonas Biofilm-Forming Functional Amyloid FapC Formation.
Science Advances,
11(39), eadx7829. Article eadx7829.
https://doi.org/10.1126/sciadv.adx7829
Rasmussen, D. K., Sun, Y. J., Franco, J. A., Kumar, A., Vu, J. T., Bassuk, A. G. & Mahajan, V. B. (2025).
Structure-function analysis of CNGA3-associated achromatopsia patient variants complements clinical genomics in pathogenicity determination.
Orphanet Journal of Rare Diseases,
20(1), Article 261.
https://doi.org/10.1186/s13023-025-03792-3
Faddy, E., Johansen, M. I., Gadeberg, C., Meyer, R. L., Østergaard, L., Bay-Richter, C., Jensen, L. K.
, Vendelbo, M. H. & Jørgensen, N. P. (2025).
[18F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute Staphylococcus aureus vascular graft infection in a rat model.
The Journal of Infectious Diseases, Article jiaf594. Advance online publication.
https://doi.org/10.1093/infdis/jiaf594
Shegefti, S., Alaei, M., Ghahari, N., Telittchenko, R., Hanafi, S. B., Isnard, S., Routy, J.-P.
, Olagnier, D. & van Grevenynghe, J. (2025).
Sustained inflammation during human T-lymphotropic virus type 1 infection: a wildfire contributing to disease progression.
Frontiers in medicine,
12, 1653384. Article 1653384.
https://doi.org/10.3389/fmed.2025.1653384
Ramiro, S., Poddubnyy, D., Mease, P. J., López-Medina, C., Kim, M., Massow, U., Taieb, V.
, Kragstrup, T. W. & McGonagle, D. (2025).
Sustained resolution of enthesitis and peripheral arthritis over 104 weeks with bimekizumab in axial spondyloarthritis.
RMD Open,
11(4), Article e005969.
https://doi.org/10.1136/rmdopen-2025-005969
Gultom, M.
, Lin, L., Brandt, C. B., Milusev, A., Despont, A., Shaw, J., Döring, Y.
, Luo, Y. & Rieben, R. (2025).
Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells.
Inflammation,
48(4), 2531–2547.
https://doi.org/10.1007/s10753-024-02208-x
Sebbag, E., Molina-Collada, J., Ndoye, R., Aletaha, D., Askling, J., Gente, K., Bertheussen, H., Bitoun, S., Bolek, E. C., Buch, M. H., Burmester, G. R., Canhão, H. M., Chatzidionysiou, K., Curtis, J. R., Danlos, F.-X., Guimarães, V., Hetland, M. L., Iannone, F., Kostine, M. ... Gottenberg, J.-E. (2025).
Systematic literature review and meta-analysis informing the EULAR points to consider on the initiation of targeted therapies in patients with inflammatory arthritis and a history of cancer.
Annals of the Rheumatic Diseases,
84(4), 643-652. Article ard-2024-225981.
https://doi.org/10.1136/ard-2024-225981
Vinken, M.
, Grimm, D., Baatout, S., Baselet, B., Beheshti, A., Braun, M., Carstens, A. C., Casaletto, J. A., Cools, B., Costes, S. V., De Meulemeester, P., Doruk, B., Eyal, S., Ferreira, M. J. S., Miranda, S., Hahn, C., Akyüz, S. H., Herbert, S., Krepkiy, D. ... Tagle, D. A. (2025).
Taking the 3Rs to a higher level: Replacement and reduction of animal testing in life sciences in space research.
Biotechnology Advances,
81, Article 108574.
https://doi.org/10.1016/j.biotechadv.2025.108574
Wolff, J. H., Skov, T. W., Haslund, D., Dorset, S. R., Revenfeld, A. L. S., Aussel, C.
, Jørgensen, S. E., Holm, M., Thomsen, M. K., Ammann, S., Cathomen, T.
, Mogensen, T. H., Møller, B. K., Bak, R. O. & Mikkelsen, J. G. (2025).
Targeted gene editing and near-universal cDNA insertion of CYBA and CYBB as a treatment for chronic granulomatous disease.
Nature Communications,
16(1), Article 7475.
https://doi.org/10.1038/s41467-025-62738-2
Staehr, C., Guldbrandsen, H. Ø., Homilius, C., Johnsen, L. Ø., Postnov, D., Pedersen, T. M., Pierre, S., Sandow, S. L.
& Matchkov, V. V. (2025).
Targeting Na,K-ATPase-Src signaling to normalize cerebral blood flow in a murine model of familial hemiplegic migraine.
Journal of Cerebral Blood Flow and Metabolism,
45(5), 842-854.
https://doi.org/10.1177/0271678X241305562
Sundvall, L., Rossen, L. S., Schack, V. R., Bundgaard, B., Rasmussen, P. V., Petersen, T.
& Höllsberg, P. (2025).
T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation.
Clinical & Experimental Neuroimmunology,
16(3), 214-226.
https://doi.org/10.1111/cen3.12818
Ding, X., Lai, X., Klaestrup, I. H., Jensen, S. R. N., Nielsen, M. M., Thorsen, K., Romero-Ramos, M., Luo, Y., Lin, L., Reinert, L. S. & Paludan, S. R. (2025).
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection.
Journal of Neuroinflammation,
22(1), Article 146.
https://doi.org/10.1186/s12974-025-03471-x
Marchal, S., Dittrich, A., Becker, N., Vogel, K., Fickenscher, L., Cortés Sánchez, J. L., Kahlert, S., Murkar, R.
, Grimm, D. & Krüger, M. (2025).
Temporary effects of random positioning on the function and plasticity of proliferating monocytes.
Scientific Reports,
15(1), Article 39360.
https://doi.org/10.1038/s41598-025-26941-x
Li, L., Ye, Y., Galimard, J. E., Labopin, M., Wu, D., Chen, J., Kröger, N., Passweg, J., Salmenniemi, U., Itäla-Remes, M., Poiré, X., Eder, M., Maertens, J., Burns, D., Sengeloev, H.
, Olesen, G., Blaise, D., Finke, J., Gadisseur, A. ... Claude Gorin, N. (2025).
TET2 mutation does not impact the prognosis of adult acute myeloid leukemia patients receiving a hematopoietic stem cell transplantation in first remission: similar outcome following matched sibling and unrelated versus haploidentical donor transplants in a multi-center retrospective analysis from the Global Committee and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.
Haematologica,
110(12), 3088-3093.
https://doi.org/10.3324/haematol.2025.287326
Omoniyi, A. A., Hammer, R. E., Josefsen, S.
, Richner, M., Lezmi, S.
, Vægter, C. B., Kalinichev, M.
, Karlsson, P. & Nyengaard, J. R. (2025).
The Activities of Recombinant Botulinum Toxin A on Spared Nerve Injury-Induced Neuropathic Pain in a Diabetic Mice Model.
Toxins,
17(11), Article 545.
https://doi.org/10.3390/toxins17110545
Prat-Duran, J., Merrild, C., Juste, N., Pinilla, E., Simonsen, U., Nørregaard, R. & Buus, N. H. (2025).
The antifibrotic potential of transglutaminase 2 inhibition beyond TGFβ1 release in human kidney tissue and isolated cell cultures.
Life Sciences,
366-367, Article 123503.
https://doi.org/10.1016/j.lfs.2025.123503
Car, J., Ong, Q. C., Erlikh Fox, T., Leightley, D., Kemp, S. J., Švab, I., Tsoi, K. K. F., Sam, A. H., Kent, F. M., Hertelendy, A. J., Longhurst, C. A., Powell, J., Hamdy, H., Nguyen, H. V. Q., Aoun Bahous, S., Wang, M., Baumgartner, M., Mahendradhata, Y., Popovic, N. ... Digital Health Systems Collaborative (2025).
The Digital Health Competencies in Medical Education Framework: An International Consensus Statement Based on a Delphi Study.
JAMA network open,
8(1), Article e2453131.
https://doi.org/10.1001/jamanetworkopen.2024.53131
Berthold, N., MacDermod, C. M., Thornton, L. M., Parker, R., Morales, S. A. C., Hog, L., Kennedy, H. L., Guintivano, J., Sullivan, P. F., Crowley, J. J., Johnson, J. S., Birgegård, A., Fundín, B. T., Frans, E., Xu, J., Ngāti Pūkenga, M. P., Miller, A. L., Aguilar, M. V., Barakat, S. ... Bulik, C. M. (2025).
The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol.
BMC Psychiatry,
25(1), Article 532.
https://doi.org/10.1186/s12888-025-06777-5
Bromer, F. D., Lodberg, A., Eijken, M., Andersen, C. B. F., Poulsen, M. F., Thomsen, J. S. & Brüel, A. (2025).
The Effect of Anti-Activin Receptor Type IIA and Type IIB Antibody on Muscle, Bone and Blood in Healthy and Osteosarcopenic Mice.
Journal of Cachexia, Sarcopenia and Muscle,
16(1), Article e13718.
https://doi.org/10.1002/jcsm.13718
Våben, C. S., Nielsen, A. W., Nielsen, M. K.
, Moll, L. T., Mørk, C.
, Dalgaard, E. B., Rasmussen, T. K., Østgård, R. D., Hansen, I. T., Nielsen, B. D., Sørensen, C. M., Blegvad-Nissen, J., Kjær, S. G., Hauge, E.-M. & Keller, K. K. (2025).
The effect of prednisolone initiation and short-term discontinuation on the clinical assessment of polymyalgia rheumatica.
Rheumatology,
64(8), 4756-4760.
https://doi.org/10.1093/rheumatology/keaf170
E. Hammer, R., A. Omoniyi, A., Richner, M., Lezmi, S.
, B. Vaegter, C., Kalinichev, M.
, Karlsson, P. & R. Nyengaard, J. (2025).
The effect of recombinant botulinum neurotoxin A on neuropathic pain in the spared nerve injury mouse model.
Journal of Neural Transmission,
132, 1779–1795.
https://doi.org/10.1007/s00702-025-02978-0
Pedersen, L., Eriksen, L. L., Brix, F. H., Vilstrup, H., Deleuran, B., Sandahl, T. D. & Støy, S. (2025).
The FGL-1/LAG-3 Axis is Associated With Disease Course in Alcohol-associated Hepatitis: A Preliminary Report.
Journal of Clinical and Experimental Hepatology,
15(1), Article 102424.
https://doi.org/10.1016/j.jceh.2024.102424
Hørsdal, O. K., Frederiksen, P. H.
, Helgestad, O. K. L., Ravn, H. B., Møller, J. E.
, Wiggers, H., Nielsen, R. R., Gopalasingam, N. & Berg-Hansen, K. (2025).
The Immediate Cardiovascular and Mitochondrial Response in Ischemic Cardiogenic Shock.
Journal of Cardiovascular Translational Research,
18(5), 1204-1217.
https://doi.org/10.1007/s12265-025-10647-6
Kipp, J. O., Petersen, E. T., Thillemann, T. M., de Raedt, S., Borgen, L., Lindgren, L., Brüel, A., Falstie-Jensen, T. & Stilling, M. (2025).
The Latarjet Procedure May Induce Pathokinematics with Posterior Humeral Head Subluxation: An Experimental Dynamic Radiostereometric Study.
Journal of Bone and Joint Surgery,
107(23), 2661-2670.
https://doi.org/10.2106/JBJS.25.00120
Chamma, H., Guha, S., Eloiflin, R. J., Augereau, A., Le Hars, P., Schüssler, M., Messaoud-Nacer, Y., Salma, M., McKellar, J., Re, J., Chemarin, M., Carrier, A., Disyak, M. A., Taffoni, C., Charpentier, R., Husson, Z., Valjent, E., Andrieu-Soler, C., Soler, E. ... Laguette, N. (2025).
The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling.
Nature Communications,
16(1), Article 9827.
https://doi.org/10.1038/s41467-025-65713-z